ctgf ccn2 in oral squamous cell carcinoma induced bone destruction

Báo cáo khoa học: Truncated P-cadherin is produced in oral squamous cell carcinoma docx

Ngày tải lên : 30/03/2014, 04:20

... activation of the E-cadherin– Truncated P-cadherin in oral squamous cell carcinoma 17 18 19 20 21 22 23 24 25 26 27 28 catenin adhesion system in a dispersed carcinoma line J Cell Biol 127, 247–256 ... role in the progression of OSSC is still elusive Truncated P-cadherin in oral squamous cell carcinoma Aberrantly expressed P-cadherin in vivo An aberrantly expressed P-cadherin was detected in ... layer in normal oral mucosa In contrast, OSCC exhibits strong overall staining in the cytoplasmic and extracellular regions of malignant cells, whereas there is an increasing loss of P-cadherin in...

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báo cáo khoa học: " Analysis of expression profiles of MAGE-A antigens in oral squamous cell carcinoma cell lines" ppsx

Ngày tải lên : 11/08/2014, 20:20

... all tumour cell lines examined Although doxorubicin is not a first-line antineoplastic agent for head and neck squamous cell carcinomas, these findings might be worthy of further investigations, ... blot of MAGE-A4 expression in cell lines examined RT-PCR3 RT-PCR blot of MAGE-A4 expression in cell lines examined Cell line PCI 52 has a splice variant Besides this finding, there is a homogenous ... hematoxylin counterstaining (400× magnification) Most cells are stained by the MAGE-A antibody Some of the cells show a strong cytosolic staining Figure cell magnification) staining line PCI 52...

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Báo cáo khoa học: " Role of p53 mutation in the effect of boron neutron capture therapy on oral squamous cell carcinoma" ppsx

Ngày tải lên : 09/08/2014, 10:20

... staining Cells were dissociated and fixed in PBS containing 1% glutaraldehyde for h After washing in PBS, cells were stained with 200 μM Hoechst 33342, mounted on slides, and visualized using ... Ohnishi T, Hosoi H: Transfection with mutant p53 gene inhibits heatinduced apoptosis in a head and neck cell line of human squamous cell carcinoma Int J Radiat Oncol Biol Phys 2000, 47:495-501 Coderre ... after BNCT in SAS/neo cells Thereafter, BNCT induced G2 arrest in both SAS/neo and SAS/mp53 cells This indicates that BNCT induces cell Figure expression and/or phosphorylation of G1 checkpoint-related...

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Báo cáo y học: "Comparative study between the Hybrid Capture II test and PCR based assay for the detection of human papillomavirus DNA in oral submucous fibrosis and oral squamous cell carcinoma" pdf

Ngày tải lên : 12/08/2014, 01:22

... (PCR): Polymerase chain reaction; (OSMF): Oral submucous fibrosis; (HNSCC): head and neck squamous cell carcinoma; (HCII): Hybrid Capture; (OSCC): Oral squamous cell carcinoma Acknowledgements ... infection in oral sub mucous fibrosis (OSMF): a potentially malignant oral lesionsa Table Concordance of results of HC-II assay and PCR test for detection of HPV infection in oral squamous cell carcinoma ... association between HR-HPV and oral lesions and might be guided future cancer prevention programs involving vaccination to oral HPV infection or screening in North Indian population Conclusion...

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Báo cáo hóa học: " Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma" doc

Ngày tải lên : 18/06/2014, 16:20

... Cytologic detection of esophageal squamous cell carcinoma and its precursor lesions using balloon samplers and liquid based cytology in asymptomatic adults in Linxian, China Acta Cytol 2008, 52:14-23 ... in esophageal squamous cell carcinoma J Cancer Res Clin Oncol 2004, 130:37-44 12 Mathew R, Khanna R, Kumar R, Mathur M, Shukla NK, Ralhan R: Stromelysin-2 overexpression in human esophageal squamous ... metalloproteinase-2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma Cancer 2004, 101:1994-2000 11 Samantaray S, Sharma S, Chattopadhyaya TK: Increased...

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Báo cáo hóa học: " Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma''''" doc

Ngày tải lên : 18/06/2014, 16:20

... Immunohistochemical staining for Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma Brown grains represent a positive signal (3, 3-diaminobenzidine staining) The positive expression ... patients with hypopharyngeal squamous cell carcinoma, suggesting that Oct4 expression may be a useful indicator for predicting the prognosis of hypopharyngeal squamous cell carcinoma Acknowledgements ... Huang CY, Lin SC, Liu CJ, Tsai TH, Chou SH, Chien CS, Ku HH, Lo JF: Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma Clin Cancer...

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Báo cáo sinh học: "MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells" pptx

Ngày tải lên : 18/06/2014, 19:20

... Although Barrett’s adenocarcinoma is the most rapidly increasing cancer in Western countries [2], esophageal squamous cell carcinoma (ESCC) is still dominant in East Asia, including Japan [3] ESCC ... adenocarcinoma cell lines (Bic-1 and Seg-1), human gastric adenocarcinoma cell lines (AGS, AZ521 and KATOIII), colorectal adenocarcinoma cell lines (Caco-2 and DLD1), a human cervix epithelioid carcinoma ... carcinoma cell line (HeLa), a human lung adenocarcinoma cell line (A549), and human hematological malignant cell lines (acute promyelotic leukemia, HL60; human T cell lymphoblast-like cell line,...

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Báo cáo sinh học: "High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

Ngày tải lên : 18/06/2014, 19:20

... Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese Carcinogenesis 2001, 22:1497-1503 Adelstein DJ, Li Y, Adams ... prognostic role of osteopontin expression in oral squamous cell carcinoma Oral Oncol 2009, 45:798-802 Department of Health EY, R.O.C.: Cancer Registry Annual Report in Taiwan Area Taipei Department ... cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis Clin Cancer Res 2000, 6:2166-2174 36 Nyati MK, Morgan MA, Feng FY, Lawrence TS: Integration of EGFR inhibitors...

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báo cáo hóa học:" High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

Ngày tải lên : 20/06/2014, 03:20

... Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese Carcinogenesis 2001, 22:1497-1503 Adelstein DJ, Li Y, Adams ... prognostic role of osteopontin expression in oral squamous cell carcinoma Oral Oncol 2009, 45:798-802 Department of Health EY, R.O.C.: Cancer Registry Annual Report in Taiwan Area Taipei Department ... cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis Clin Cancer Res 2000, 6:2166-2174 36 Nyati MK, Morgan MA, Feng FY, Lawrence TS: Integration of EGFR inhibitors...

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Báo cáo khoa học: "Delayed diagnosis of oral squamous cell carcinoma: a case series" pdf

Ngày tải lên : 10/08/2014, 23:21

... SO: Oral squamous cell carcinoma: an analysis of 1,564 cases showing advances in early detection J Oral Sci 2010, 52:267-273 Gao W, Guo CB: Factors related to delay in diagnosis of oral squamous ... SL, Aleksejūniene J, Zed C, Dharamsi S, Thinh DH, Hong NT, Cuc TT, Thao NT: The oral squamous cell carcinoma and cultural oral risk habits in Vietnam Int J Dent Hyg 2010, 8:159-168 Marocchio LS, ... squamous cell carcinoma J Oral Maxillofac Surg 2009, 67:1015-1020 Hendrikx AWF, Maal T, Dieleman F, Van Cann EM, Merkx MAW: Cone-beam CT in the assessment of mandibular invasion by oral squamous cell...

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The expression of CD44s in squamous cell carcinoma of the oral tongue and association with clinicopathological factors and survival outcomes

Ngày tải lên : 02/10/2015, 17:14

... population of cells with cancer stem cell characteristics in head and neck squamous cell carcinoma (HNSCC) The aim of this study is to investigate the expression of CD44s in squamous cell carcinoma (SCC) ... cancer on the decline in the developed world, a rising incidence suggests a continuing increase in the absolute numbers of cases to be treated in the coming decades.3 In India, incidence rates ... Cancer stem cells in Head and Neck Squamous Cell Carcinoma In head and neck squamous cell carcinoma (HNSCC), Prince et al first isolated a highly tumourigenic subpopulation of cancer cells that...

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Báo cáo y học: "Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/ cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma"

Ngày tải lên : 26/10/2012, 09:53

... nephrotoxicity and gastrointestinal toxicity than CDDP [14] In phase II clinical studies, NDP was found to be highly effective against solid tumors, including non-small cell lung cancer, small cell lung cancer, ... esophageal cancer, and treatments include surgical procedures, radiation, chemotherapy, and combinations thereof [10] In patients with localized squamous cell carcinoma, a definitive 5-FU/CDDP-based CRT ... radical surgery in patients with T(2-3) N(any) M(0) squamous cell carcinoma of the esophagus Int J Radiat Oncol Biol Phys 2003; 57: 425-33 Tobinai K, Kohno A, Shimada Y, et al Toxicity grading criteria...

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Báo cáo hóa học: "Anti-CDC25B autoantibody predicts poor prognosis in patients with advanced esophageal squamous cell carcinoma" pptx

Ngày tải lên : 18/06/2014, 16:20

... humidified incubator containing 5% CO2 at 37°C The immortalized esophageal cell line NE-3 was obtained from Dr Jin (the University of Hong Kong, P R China)[26] and cultured in KeratinocyteSFM (Invitrogen, ... Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma Surgery 2003, 133:486-494 Sobin LH, Fleming ID: TNM Classification of ... protein in esophageal squamous cell carcinomas and premalignant lesions in subjects from a high-risk population in China Cancer Epidemiol Biomarkers Prev 2008, 17:1424-1435 26 Zhang H, Jin Y,...

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Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot

Ngày tải lên : 18/06/2014, 22:20

... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... staining was restricted in cytoplasm in laryngeal carcinoma[ 12] The discrepancies may be partially explained by the difference of antibodies used for staining or method of assessment for determination ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non-specific staining, the section was incubated with protein block (DakoCytomation)...

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báo cáo hóa học:" Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" doc

Ngày tải lên : 20/06/2014, 04:20

... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... staining was restricted in cytoplasm in laryngeal carcinoma[ 12] The discrepancies may be partially explained by the difference of antibodies used for staining or method of assessment for determination ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non-specific staining, the section was incubated with protein block (DakoCytomation)...

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báo cáo hóa học:" Squamous cell carcinoma in situ arising in mature cystic teratoma of the ovary: a case report" ppt

Ngày tải lên : 20/06/2014, 07:20

... V, Mittal S: Squamous cell carcinoma in situ arising in mature cystic teratoma Indian J Pathol Microbiol 2002, 45(3):345-6 Chen Ruey-Jien, Chen Ko-Yang, Chang Ting-Chen, Sheu Bor-Ching, Chow Song-Nan, ... Treatment of Squamous Cell Carcinoma from a Mature Cystic Teratoma of the Ovary J Formos Med Assoc 2008, 107(11) Dos Santos L, Mok E, Iasonos A: Squamous cell carcinoma arising in mature cystic ... prognostic factors [10] Due to the relative rarity of the squamous cell carcinoma in situ arising in MCT, there is no uniform consensus regarding treatment However, the treatment for many authors...

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Báo cáo khoa học: "Intradural squamous cell carcinoma in the sacrum" potx

Ngày tải lên : 09/08/2014, 04:21

... of squamous cell carcinoma with intradural spinal metastasis in which the initial symptoms appeared in the spinal cord and cauda equina, but not in the brain Author Age Gender Primary tumor Involved ... indicate that cases of primary intradural squamous cell carcinoma in the spine are very rare In our patient, there were no apparent primary lesions of squamous cell carcinoma in any organ and no cranial ... even in the lungs, thus the origin of the squamous cell carcinoma remained unknown We found the case of a 56-year-old patient with primary (but not metastatic) intradural squamous cell carcinoma...

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báo cáo khoa học: "Antisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude mice" docx

Ngày tải lên : 10/08/2014, 10:21

... China) Cell lines and mice Hep-2 cell line was obtained from the laboratory of Head and Neck at Sichuan University The cells were maintained in RPMI-1640 medium, supplemented with 10% heat-inactivated ... radio -induced apoptosis in vitro and in vivo Here we show that transgenic expression of ATM ASODNs into hep-2 cells on its own induced the inhibitory expression of ATM at mRNA and protein level in ... strengthening radio -induced apoptosis of hep-2 cell line grown in nude mice In conclusion, radiotherapy combined with AS-ODNs could specifically reduce the ATM expression and increase radio-induced...

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báo cáo khoa học: "Different patterns of NF-B and Notch1 signaling contribute to tumor-induced lymphangiogenesis of esophageal squamous cell carcinoma" ppt

Ngày tải lên : 10/08/2014, 10:21

... conserved proteins regulate “decisions” involved in cell- fate determination, including those involved in mammalian vascular development [15] The finding that genes of the Notch signaling cascade ... immunohistochemical staining Nuclear staining of NF-B and cytoplasmic staining of Notch1 and VEGF-C were scored in this study The intensity of NF-B, Notch1, podoplanin, and/or VEGFC staining was score ... role of Notch signaling during tumorigenesis, the finding that Notch signaling is diminished in epithelial squamous cell carcinoma of the skin would seem to suggest that Notch might serve as a...

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