... inducible nitricoxide synthase gene expression in vascular smooth muscle cells Gen Pharmacol 32, 9–16 19 Kim, S.-J., Bang, O.-S., Lee, Y.-S & Kang, S.-S (1998) Production of inducible nitricoxide ... be caused by differences in the response, delivery and distribution of TS in each cell line Recently, we found that TS-induced apoptosis of VSMC was caused by the stimulation of superoxide production ... antineoplastic role Redox Report 6, 143–151 17 Jeremy, J.Y., Rowe, D., Emsley, A.M & Newby, A.C (1999) Nitricoxide and the proliferation of vascular smooth muscle cells Cardiovasc Res 43, 580–594...
... (2002) Hydrogen peroxide induces a rapid production of nitricoxide in mung bean (Phaseolus aureus) NitricOxide 6, 205–213 41 Neill SJ, Desikan R, Clarke A & Hancock JT (2002) Nitricoxide is a novel ... of nitricoxide from plants and some other organisms by mass spectrometry Plant J 38, 1015–1022 25 Kaiser WM, Planchet E & Sonoda M (2004) NO emission by plants, and sources for NO NitricOxide ... synthesis of nitricoxideby plant tissues Plant Cell 16, 332–341 35 Bethke PC, Gubler F, Jacobsen JV & Jones RL (2004) Dormancy of Arabidopsis seeds and barley grains can be broken bynitric oxide...
... suppression of the expression and activity of inducible nitricoxide synthase (iNOS) by zinc [32,33], released from MT under the influence of nitricoxide (NO), and the scavenging of NO through covalent ... Inhibition of nitricoxide synthase activity by Zn2+ ion Biochemistry 34, 15091–15095 33 Abou-Mohamed, G., Papapetropoulos, A., Catravas, J.D & Caldwell, R.W (1998) Zn2+ inhibits nitricoxide formation ... Discussion The presented results show clearly that the metal release from MT2 bynitricoxide and peroxynitrite is suppressed by reduced but not oxidized glutathione Due to different requirements of...
... neuronal nitric- oxide synthase by a dual mechanism Activation of intra- and interdomain electron transfer J Biol Chem 269, 1179–1190 Chen PF, Tsai AL, Berka V & Wu KK (1996) Endothelial nitric- oxide ... nitric- oxide synthase isozymes by calmodulintroponin C chimeras J Biol Chem 279, 33547–33557 14 Persechini A, McMillan K & Leakey P (1994) Activation of myosin light chain kinase and nitricoxide ... electron transfer by inducible nitricoxide synthase Biochemistry 44, 7593–7601 29 Newton DC, Montgomery HJ & Guillemette JG (1998) The reductase domain of the human inducible nitricoxide synthase...
... macrophages by blocking mTOR activity G-CSF functions as an anti-inflammatory cytokine by activating antibacterial defense by neutrophils and by reducing the release of proinflammatory mediators, thereby ... on nitricoxide production J Immunol 161, 6947–6954 Jin HK, Ahn SH, Yoon JW, Park JW, Lee EK, Yoo JS, Lee JC, Choi WS & Han JW (2009) Rapamycin down-regulates inducible nitricoxide synthase by ... effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitricoxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production Inflamm Res 49, 20–26 Lu SC, Chang SF,...
... proteasome in activation of endothelial nitricoxide synthase Life Sci 73, 2225–2236 Musial A & Eissa T (2001) Inducible nitric- oxide synthase is regulated by the proteasome degradation pathway ... NOS isozymes by calpain 44 Araujo IM, Ambrosio AF, Leal EC, Santos PF, Carvalho AP & Carvalho CM (2003) Neuronal nitricoxide synthase proteolysis limits the involvement of nitricoxide in kinate-induced ... Regulation of endothelial nitricoxide synthase by the FEBS Journal 274 (2007) 6116–6127 ª 2007 The Authors Journal compilation ª 2007 FEBS 6125 Degradation of NOS isozymes by calpain 10 11 12 13...
... of NO by neuronal nitricoxide synthase (nNOS) [10] These particular amphibian peptides (e.g the caerins and splendipherin [11]), are basic and hinged, and inhibit the operation of nNOS by complexing ... within Ca2+-CaM [25]: this type of structure is also adopted by Ca2+-CaM when it binds to the CaM-binding domain of endothelial nitricoxide synthase (eNOS) [33] The second example is when the C-terminal ... conducted by the Australian Institute of Marine Science (Townsville, Australia) Inhibition was measured and analyzed by monitoring the conversion of [3H]arginine to [3H]citrulline by nNOS, using...
... with nitricoxide synthases: controlling the right time, the right place, and the right amount of nitricoxide Am J Physiol Renal Physiol 285, 178–190 In vivo degradation of NOS and HSP90 by calpain ... of inducible nitricoxide synthase is required for its degradation Proc Natl Acad Sci USA 99, 12315–12320 15 Musial A & Eissa T (2001) Inducible nitric- oxide synthase is regulated by the proteasome ... cleavage of inducible nitricoxide synthase (iNOS) by calpain I Biochim Biophys Acta 1568, 216– 224 23 Su Y & Block ER (2000) Role of calpain in hypoxic inhibition of nitricoxide synthase activity...
... iNOS, inducible nitricoxide synthase; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor kappa B; NGF, nerve growth factor; NO, nitric oxide; nNOS, neuronal nitricoxide synthase; ... Regulation by cytokines of the inducible nitricoxide synthase promoter in insulin-producing cells Diabetologia 1998, 41:1101-8 Kong GY, Peng ZC, Costanzo C, Kristensson K, Bentivoglio M: Inducible nitric ... Acknowledgements This work was supported in part by a research development grant by the UTMB Sealy Endowed Fund for Biomedical Research Michael Thomas is supported by an NIEHS training grant pre-doctoral...
... University and in part by the Korea Research Foundation Grant funded by the Korean Government (KRF-2008- 521-E00146) References Albina JE, Cui S, Mateo RB, Reichner JS Nitric oxidemediated apoptosis ... through the up-regulation of nitricoxide and tumor necrosis factor-alpha from peritoneal macrophages J Ethnopharmacol 2004, 95, 69-76 Kim YM, Bombeck CA, Billiar TR Nitricoxide as a bifunctional ... Lowenstein CJ, Dinerman JL, Snyder SH Nitric oxide: a physiologic messenger Ann Intern Med 1994, 120, 227-237 14 Moncada S, Palmer RMJ, Higgs EA Nitric oxide: physiology, pathophysiology, and...
... mice by the inhibition of TGF-beta signaling in lung fibroblasts Respir Res 2006, 7:16-29 13 Tayler BS, Geller DA: Regulation of the inducible nitricoxide synthase (iNOS) gene In Nitricoxide ... Immunol 2002, 110:349-356 23 Cuzzocre S: Role of nitricoxide and reactive oxygen species in arthritis In Nitricoxide and inflammation Edited by: Salvemini D, Billiar TR, Vodovotz Y Basel, Birkhauser ... Ebrahimkhani M, Kiani S, Dehpour A: Nitric oxide: a new concept in chronic sinusitis pathogenesis Am J Otolaryngol 2007, 28:334-337 27 Francoeur C, Denis M: Nitricoxide and interleukin-8 as inflammatory...
... mice by the inhibition of TGF-beta signaling in lung fibroblasts Respir Res 2006, 7:16-29 13 Tayler BS, Geller DA: Regulation of the inducible nitricoxide synthase (iNOS) gene In Nitricoxide ... Immunol 2002, 110:349-356 23 Cuzzocre S: Role of nitricoxide and reactive oxygen species in arthritis In Nitricoxide and inflammation Edited by: Salvemini D, Billiar TR, Vodovotz Y Basel, Birkhauser ... Ebrahimkhani M, Kiani S, Dehpour A: Nitric oxide: a new concept in chronic sinusitis pathogenesis Am J Otolaryngol 2007, 28:334-337 27 Francoeur C, Denis M: Nitricoxide and interleukin-8 as inflammatory...
... respond to inhaled nitricoxide Am J Perinatol 2001, 13:185-194 Gow AJ: The biological chemistry of nitricoxide as it pertains to the extrapulmonary effects of inhaled nitricoxide Proc Am Thorac ... influence of inhaled nitricoxide on cerebral blood flow and metabolism in a child with traumatic brain injury Anesth Analg 2001, 93:351-353 Griffiths MJD, Evans TW: Inhaled nitricoxide therapy in ... nitric oxide: mechanism(s) and physiologic versus pathological relevance Am J Respir Cell Mol Biol 2005, 32:257-261 Kosaka H, Watanabe M, Yoshihara H, Harada N, Shiga T: Detection of nitric oxide...
... functions by several ways (17) NO is synthesized from arginine bynitricoxide synthase (NOS; EC 1.14.13.39), and the citrulline generated as a by- product can be recycled to arginine by successive ... modulation by NMDA receptors and nitricoxide Neurochem Int 2003; 43: 493-499 33 Rose C, Felipo V Limited capacity for ammonia removal by brain in chronic liver failure: potential role of nitricoxide ... hypoxia on the nitricoxide system of the rat cerebral cortex: Protective role of nitricoxide inhibitors Neuroscience 2006; 142: 799-808 44 Nomura EA, Kitamura Y Inducible nitricoxide synthase...
... could involve stimulation of nitricoxide synthesis and thereby reversal of endothelial dysfunction [23, 24] Alternative possibilities, also possibly related to nitric oxide, include improvements ... its influence on nitricoxide synthesis had implications for disease pathogenesis, as has been suggested [26] We could explain this extraordinary difference in the risk of death by proposing either ... beverages consumed by Kuna Amerinds of Panama J Food Compos & Analysis 2001; 14:553-563 23 Fisher ND, Hughes M, Gerhard-Herman M, et al Flavanol-rich cocoa induces nitric- oxide- dependent vasodilation...
... factor and the chemical reactivity of nitricoxide J Exp Med 169, 1011–1020 Abu-Soud HM & Stuehr DJ (1993) Electron transfer in the nitric- oxide synthases Nitricoxide synthases reveal FEBS Journal ... (1997) A tutorial on the diffusibility and reactivity of free nitricoxideNitricOxide 1, 18–30 Salerno JC (2008) Neuronal nitricoxide synthase: prototype for pulsed enzymology FEBS Lett 582, ... properties of nitric- oxide synthase oxygenase ⁄ FMN domain constructs J Biol Chem 281, 14173–14183 43 Roman LJ & Masters BSS (2006) Electron transfer by neuronal nitric- oxide synthase is regulated by concerted...