0

cruciferous vegetables and their components in the prevention of breast cancer

the role of ikkalpha, ikkbeta and nf-kappab in the progression of breast cancer

the role of ikkalpha, ikkbeta and nf-kappab in the progression of breast cancer

Tổng hợp

... 16% of familial breast cancers not being linked to either of these genes [23] Mutations in both BRCA1 and BRCA2 also increase the risk of ovarian cancer In families with a history of breast and ... phosphorylated and processed into p52 The processing of p100 to p52 results in the loss of the ankyrin repeats in the C-terminus and allows translocation of the RelB/p52 dimers into the nucleus ... been added with the division of the luminal subtype into luminal A and B, and the inclusion of the claudin-low subtype [50-51] Both the luminal A and B subtypes show expression of ER, PgR or ER...
  • 233
  • 425
  • 0
Báo cáo y học:

Báo cáo y học: "Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis" pdf

Báo cáo khoa học

... in substrate specificities, and the MMPs appear to be involved in degradation of abundant ECM components, including laminins, collagens and fibronectin, but also in the release and turnover of ... this review The gelatinases cleave a number of substrates, including native forms of collagens I, IV, V, VII, X and XI, elastin, laminin, fibronectin, myelin and the core protein of proteoglycans ... diseases of the glomerulus, the results of studies of the involvement of MMP activity in other renal pathologies should provide valuable guidance in elucidating the role of these enzymes in lupus...
  • 8
  • 493
  • 0
The chemical components of detergents and their roles in the washing process

The chemical components of detergents and their roles in the washing process

Hóa học - Dầu khí

... fabrics and on the washing machine’s heating elements - stabilise alkalinity at the correct level throughout the washing process thus giving good soil removal and enabling the other components of the ... necessarily involves the inclusion of a number of complex, new chemicals and a complete restructuring on the detergent's formula, often with significant increase in other existing ingredients For each of ... break up large particles of dirt into smaller ones, which can be washed out, and they help prevent fine dirt particles from combining and thus keep them in suspension in the wash water Phosphates...
  • 5
  • 482
  • 0
Characteristics of Leachate from Citrus Groves and their Changes in the Collecting Reservoirs in Matsuyama, Japan

Characteristics of Leachate from Citrus Groves and their Changes in the Collecting Reservoirs in Matsuyama, Japan

Môi trường

... the middle parts of the grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the other stream The two streams flow together to be one stream and ... and periphery of the Seto Inland Sea The location of the research area and the distribution of the citrus groves in Matsuyama region are shown in Fig Matsuyama is situated in Shikoku Island in ... kind of citrus called Iyokan is mainly cultivated There are two small streams on the upper part of the hill and the streams flow together from 47 m above sea level The water in the stream is the...
  • 10
  • 717
  • 0
TALENT AGENTS, PERSONAL MANAGERS, AND THEIR CONFLICTS IN THE NEW HOLLYWOOD docx

TALENT AGENTS, PERSONAL MANAGERS, AND THEIR CONFLICTS IN THE NEW HOLLYWOOD docx

Sân khấu điện ảnh

... traditional agents Notwithstanding the TAA, they often procure employment for their upand-coming clients, and with Tobin under their belts, they often legally procure employment for their more established ... advantage: They retain managers in their early years to procure employment, and then they get the Labor Commissioner to rescind their contracts once they establish their reputations 112 In addition ... strong stake in maintain ing extended agreements in order to protect their ability to receive returns on the time and money they have invested in their clients during earlier, less profitable years.97...
  • 24
  • 713
  • 0
báo cáo hóa học:

báo cáo hóa học:" Current status of medication adherence and infant follow up in the prevention of mother to child HIV transmission programme in Addis Ababa: a cohort study" potx

Hóa học - Dầu khí

... data, interpreted the findings and wrote the manuscript OM was involved in developing the study proposal, supervising the data collection and reviewing the manuscript SGH was involved in developing ... developing the study proposal and reviewing the manuscript MMS was involved in supervising the data collection and reviewing the manuscript KMM was involved in developing the study proposal and reviewing ... group where mothers and infants initiated the intrapartum and postpartum prophylaxis doses, whereas it was 14.2% in the group where mothers, but not their infants, initiated the intrapartum dose...
  • 10
  • 712
  • 0
Báo cáo hóa học:

Báo cáo hóa học: " Some new nonlinear integral inequalities and their applications in the qualitative analysis of differential equations" potx

Hóa học - Dầu khí

... prove the global existence of the solutions of a delay differential equation, while in the second example, we will obtain the bound of the solutions of an integral equation For the sake of proving ... general theorems and establish some new integral inequalities Also we will give some examples so as to illustrate the validity of the present integral inequalities Main results In the rest of the ... denote the set of real numbers as R, and R+ = [0, ∞) is a subset of R Dom(f) and Im(f) denote the definition domain and the image of f, respectively Theorem 2.1: Assume that x, a Î C(R+, R+) and...
  • 15
  • 430
  • 0
Báo cáo hóa học:

Báo cáo hóa học: " Research Article New Trace Bounds for the Product of Two Matrices and Their Applications in the Algebraic Riccati Equation" potx

Hóa học - Dầu khí

... 3.1 In this section, we obtain the application in the algebraic Riccati equation of our results including 3.1 Some of our results and 3.1 cannot contain each other Theorem 3.1 If 1/p and K is the ... Majorization and Its Applications, vol 143 of Mathematics in Science and Engineering, Academic Press, New York, NY, USA, 1979 17 C.-L Wang, “On development of inverses of the Cauchy and Holder inequalities,” ... 2 Journal of Inequalities and Applications where x0 ∈ Rn is the initial state of the systems 1.1 and 1.2 , K is the positive definite solution of the following algebraic Riccati equation...
  • 18
  • 456
  • 0
elements and their compounds in the environment occurence analysis and biological relevance

elements and their compounds in the environment occurence analysis and biological relevance

Kinh tế vĩ mô

... Contamination of the Environment 1117 Inorganic Tin 1117 Organic Tin 1118 Contamination of Food and Living organisms 1119 Uptake, Absorption and Elimination in Plants, Animals and Humans 1120 Tin and ... KGaA, Weinheim ISBN: 3-527-30459-2 VI Preface tent of the book In the course of the preliminary planning phase, including the six members of the Editorial Advisory Board (three former and three ... Products and Recycling 601 Sources 601 Production and Uses 601 Important Compounds and their Uses 601 Waste Products and Recycling 604 Distribution in the Environment, in Foods and in Living Organisms...
  • 1,795
  • 1,497
  • 1
Báo cáo y học:

Báo cáo y học: "Practical and theoretical barriers to the prevention of accelerated atherosclerosis in systemic lupus erythematosus" docx

Báo cáo khoa học

... and medications Progress will only be made as basic science brings an understanding of the mechanisms of accelerated atherosclerosis in SLE and as clinical studies address both the efficacy and ... little reinforcement from their providers In recruiting patients with SLE and hyperlipidemia for a statin dosing study, our experience has been that the patients who are the most willing to participate ... normal individuals is simple and neat, but might be wrong or incomplete 10 11 12 Several questions remain unanswered in our search for a successful approach to the prevention of ASVD in SLE The...
  • 2
  • 366
  • 0
Báo cáo khoa học:

Báo cáo khoa học: " A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients" pdf

Báo cáo khoa học

... to the affected area with the bare hand Application of the cream was accomplished with the ventral surface of the fingers using a rotary motion of the fingers with light pressure to the skin The ... administered in the same manner and on the skin of the same patient, we removed the individual effects by analyzing the difference of the two scores (i.e., gel score – cream score) rather than the ... at reducing the drying effect of radiation on the skin and involves instructing patients to avoid irritating the irradiated region Dryness due to RT leads to desquamation and loss of the superficial...
  • 8
  • 562
  • 0
Báo cáo y học:

Báo cáo y học: " Change in quality of life and their predictors in the long-term follow-up after group cognitive behavioral therapy for social anxiety disorder: a prospective cohort study" pptx

Báo cáo khoa học

... conceived of the study, performed the clinical investigation (diagnosis, treatment and assessment), and drafted the manuscript TAF participated in the design of the study and performed the clinical investigation ... statistically significant changes in the domains of the SF-36 or to detect potential baseline predictors of the SF-36 at the follow-ups Nevertheless, the changes of each of the SAD symptomatology scores ... any of the QoL domains throughout follow-up for up to 12 months The most striking finding of the current study may be that the social functioning domain, which is significantly impaired in patients...
  • 10
  • 388
  • 0
Báo cáo y học:

Báo cáo y học: " Recently published papers: A review of novel strategies in the prevention of hospital-acquired infections, the ability of intensivists to perform echocardiography, and the benefit of polymyxin B haemoperfusion in abdominal sepsis" pot

Báo cáo khoa học

... using transthoracic ultrasound [11] They trained a group of intensivists with hours of didactic teaching and hours of practical teaching, and provided a range of pre-recorded examinations for the ... occupational therapy) In their group of 104 patients, early physical and occupational therapy significantly increased the number of patients who had returned to independent functional status by the point ... evaluated the degree of certainty that the intensivists held over their findings, it would help to illustrate whether inappropriate changes of management might have resulted from their transthoracic...
  • 3
  • 471
  • 0
Báo cáo y học:

Báo cáo y học: "Emergency Department Triage Scales and Their Components: A Systematic Review of the Scientific Evidence" pptx

Báo cáo khoa học

... Since the study recorded the risk of dying during the in- hospital stay, mortality was higher than in the studies on ATS and CTAS In using the need of hospitalization as a measure of safety, the ... Development of triage scales in some countries has been influenced largely by the seminal work of FitzGerald [11], resulting in most of the triage scales developed in the 1990s and 2000s being designed ... that in the construction of triage scales, much of the information was deduced from studies performed in settings other than EDs Strengths and limitations The strength of this review of the scientific...
  • 13
  • 488
  • 0
Tài liệu Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study pdf

Tài liệu Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study pdf

Sức khỏe giới tính

... positive, two were in the placebo of invasive breast cancer in the placebo group and three in the group and one was in the tamoxifen group The rate of invasive breast cancer among women in the tamoxifen ... design of the study included formal interim monitoring for early stopping based on the primary end point of the trial, i.e., the incidence of invasive breast cancer The stopping rule of Fleming ... on the heart One of the original aims of the P-1 study was to determine whether tamoxifen reduced the risk of fractures of the hip, radius (Colles’), and spine The current findings indicating...
  • 18
  • 645
  • 0
Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx

Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx

Báo cáo khoa học

... partitioning of the protein into an aggregated state The effect of copper binding on the secondary structure was determined using CD in the far UV To prepare proteins without Cu2+, part of each protein ... copper binding could still allow domain swapping to occur It is of interest that a N-terminally truncated prion protein, lacking the copper binding domain is capable of domain swapping and forms ... understanding what causes the loss of appropriate metal binding might be crucial for the understanding of the role of amyloidogenic proteins in a number of neurodegenerative disorders Copper binds...
  • 14
  • 586
  • 0
Báo cáo khoa học: Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions pptx

Báo cáo khoa học: Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions pptx

Báo cáo khoa học

... application of SH2 domain binding peptides, which results in blocking of the binding of the SH2 domain to the substrate and thereby preventing interaction of the substrate with the kinase domain For ... C-terminus Kinase domain and C-terminus SH3 domain and C-terminus SH2 domain and C-terminus SH3, SH2 domain and C-terminus N-terminal, SH3, SH2 domain and C-terminus N-terminal, SH3, SH2, kinase ... tyrosine kinase, the SH2 and SH3 domains are redistributed from their auto-inhibitory positions at the back site of the kinase domain, adopting an extended conformation and stimulating the catalytic...
  • 11
  • 597
  • 0
AN ACCOUNT OF TIMBUCTOO AND HOUSA, TERRITORIES IN THE INTERIOR OF Africa docx

AN ACCOUNT OF TIMBUCTOO AND HOUSA, TERRITORIES IN THE INTERIOR OF Africa docx

Du lịch

... and if no person of the royal line be the object of their choice, they may elect one of their own body The members of the council are appointed by the king; he chooses them for their wisdom and ... goods brought in by the gate of the Nile, (which is the gate of the Negroes,) pay a tax: another part of the revenue is two per cent, in kind on the produce of the land; but the people of Barbary ... buried in a winding-sheet and a coffin: the relations mourn over their graves, and pronounce a panegyric on the dead The men and women mix in society, and visit together with the same freedom as in...
  • 387
  • 381
  • 0
Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

Báo cáo khoa học

... [21–25], and DGD° values in the presence of these osmolytes are given in Table However, DGD° values of RNase-A in the presence of alanine, serine, lysine, b-alanine, taurine and dimethylglycine have ... efficiency in the presence of this group of osmolytes Interestingly, there is a linear relationship between DDGD° and Dlog(kcat ⁄ Km) in the presence of methylamines and sugar However, the slopes of the ... (a) the main driving force for the folding is the unfavourable interaction between the osmolyte and the peptide backbone, and (b) the total contribution of side chains to the stability of the...
  • 9
  • 547
  • 0
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

Báo cáo khoa học

... ATP into contact in the absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e inhibiting ... concentrations of curcumin (25 mM ) the Km for the catalytic site is also possibly increased In order to further assess the possibility of curcumin affecting the interaction of ATP binding to the ATPase, ... about mM Reversing the order of addition to the ATPase (i.e curcumin then ATP) had a similar effect on the extent of ATP binding, i.e in both cases, the amount of ATP binding to the ATPase was...
  • 10
  • 594
  • 0

Xem thêm