crohn s disease may affect the gastrointestinal gi tract from the pharynx to the anus what are the most common clinical patterns of gi involvement
Báo cáo Y học: Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn’s disease ppt
Ngày tải lên :
31/03/2014, 23:20
... assigned using DQF-COSY and TOCSY, and the data are summarized in Table Two sets of sugar signals were observed The coupling constants of the signals revealed a glucopyranosyl configuration As ... and the corresponding sugars were designated as a and b in order of 1H chemical shift The 1H signals were assigned using DQF-COSY, TOCSY and ROESY spectra, and the 13C signals were assigned using ... OPS The spectra were measured at 303 K in D2O The chemical shifts are expressed as d values (p.p.m.) The coupling constants are in parentheses nd, Not determined; a¢ is estimated to be the nonsubstituted...
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Báo cáo y học: "Association of the T allele of an intronic single nucleotide polymorphism in the colony stimulating factor 1 receptor with Crohn''''s disease: a case-control study" ppt
Ngày tải lên :
11/08/2014, 10:23
... patients with Crohn' s disease We also show, using immunohistochemistry, that the CSF1R protein is expressed in the superficial epithelium of the ileum and colon *This SNP occurs 2033 base pairs from ... case-control study, we have shown that a SNP in an intron of this gene is associated with Crohn' s disease Whether this SNP is in close proximity to another disease- causing SNP in the same (or a ... binding sites in several introns [35], complete sequencing of each of these sites will be performed to investigate the hypothesis that defective RUNX1 binding is related to Crohn' s disease susceptibility...
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Is Lactobacillus GG Helpful in Children With Crohn’s Disease? Results of a Preliminary, Open-Label Study docx
Ngày tải lên :
05/03/2014, 12:20
... immunomodulatory drugs for at least months before screening and stable doses of prednisone for at least weeks before the screening visit Patients were allowed to decrease the steroid dose during the study ... weeks of LGG therapy The PCDAI was calculated at each visit Stools were cultured at each follow-up visit to assess colonization by LGG Intestinal permeability was assessed by a cellobiosemannitol ... patients had relapse of Crohn s disease within to 12 weeks of discontinuation of LGG One patient subsequently needed colectomy and one patient had ileocecal resection DISCUSSION Although the cause of...
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Infliximab therapy in pediatric Crohn’s disease: a review docx
Ngày tải lên :
22/03/2014, 10:20
... 15 had serious infection (2 fatal sepsis, pneumonia, severe viral gastroenteritis, abdominal abscess, arm cellulitis, histoplasmosis).53 Other studies also suggest the occurrence of Listeria ... patients achieved disease remission on mesalamine, less than 50% of patients were able to sustain disease remission after one year of maintenance therapy.9 Although studies have shown that corticosteroids ... medication Seventy-seven percent of patients in the REACH had inconclusive HACA results HACA causes infusion reactions (acute and delayed), shortened response and also loss of response Risk factors for...
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INTENSIVE LIFESTYLE CHANGES MAY AFFECT THE PROGRESSION OF PROSTATE CANCER docx
Ngày tải lên :
29/03/2014, 01:20
... FBS served as a control for each assay and results are expressed as percent FBS Cell growth was assessed by MTS Assay (Promega, Madison, Wisconsin) For apoptosis cells were plated at a density of ... measures was done while blinded to group assignment Baseline equivalence of the groups was analyzed using the independent sample t test in the case of continuous variables and the chi-square test ... analysis, we correlated the degree of lifestyle change with changes in serum PSA, LNCaP cell growth, LNCaP apoptosis, serum testosterone and CRP across the groups regardless of group assignment...
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CROHN''''S DISEASE pdf
Ngày tải lên :
27/06/2014, 16:20
... molecule expression occur in the intestinal mucosa of patients with inflammatory bowel diseases The fact that these alterations appear to be mainly confined to the crypts in these diseases, as summarized ... 10 Crohn' s Disease mucosa being apoptosis-resistant (Francoeur et al 2009) Distinct intrinsic properties of myofibroblasts isolated from inflammatory bowel disease vs non-inflammatory bowel disease ... counterparts We thus investigated the possibility that a loss of pericryptal myofibroblasts occurs in the inflamed regions of CD mucosa by testing myofibroblast susceptibility to the same panel of proinflammatory...
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Báo cáo sinh học: "Mycobacterium avium subsp. paratuberculosis linked to Crohn''''s Disease and Paratuberculosis" pot
Ngày tải lên :
08/08/2014, 19:20
... antibiotic regimens against MAP In conclusion, these results might represent a good starting point to consider different drugs for treatment of the disease forms where involvement of MAP is suspected, ... independently of the isolation source, which is in contrast with previous reports [9-11] A number of antimicrobial agents have been used to combat flare ups in Crohn' s Disease These have included Ciprofloxacin ... ciprofloxacin are widely used antibiotics, strains resistant to these drugs can be very common Up to now, there is a urgent need of new information on the activity of available antibiotic regimens...
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Báo cáo y học: "ncreased serum HO-1 in hemophagocytic syndrome and adult-onset Still''''s disease: use in the differential diagnosis of hyperferritinemia" docx
Ngày tải lên :
09/08/2014, 06:22
... hemophagocytosis [20-22] The disease is subdivided into two categories, familial lymphohistiocytosis and secondary HPS, the latter of which is associated with rheumatic diseases such as systemic-onset ... resembling these signs in HPS Lack of specific disease markers often delays diagnosis of HPS and ASD, with potentially lethal consequences [21] The present study shows that serum HO-1 levels are ... whereas it is sometimes hard to diagnose secondary HPS, especially in adults Although the diagnosis requires the histological identification of hemophagocytosis in organs, the findings are often...
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Báo cáo y học: "Adalimumab - an effective and promising treatment for patients with fistulizing Crohn’s disease: a case series" pdf
Ngày tải lên :
11/08/2014, 00:23
... of ECF includes controlling sepsis, optimization of the nutritional state, wound care, assessment of the fistula anatomy, and the timing of surgery and surgical strategy (the SOWATS guideline), ... achieved a remission of the disease and a complete spontaneous closure of the postoperative ECF in both cases Conclusions The results from a meta-analysis by Peyrin-Biroulet et al demonstrate that ... anti-TNF therapy is safe and effective for both luminal and FCD, in patients who are Page of refractory to standard medical therapy Due to the small sample size of these drugs, it was not possible to...
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Báo cáo y học: "Perforated Meckel’s diverticulum presenting with combined bowel and urinary obstruction and mimicking Crohn’s disease: a case report" pps
Ngày tải lên :
11/08/2014, 03:21
... reports of patients with Meckel s diverticulum masquerading as Crohn s disease are rare [12], but cases of patients with Meckel s diverticulum associated with confirmed Crohn s disease are not uncommon ... of the case Due to the lack of ectopic gastric mucosa in the resected specimen, the scan would not have assisted in diagnosis even if performed Laparoscopy did not lead to the diagnosis due to ... no other obvious abnormalities were seen to support a diagnosis of Crohn s disease or malignancy Fecal diversion was deemed unnecessary because the perforated Meckel s diverticulum was felt to...
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Báo cáo y học: "Perforated Meckel’s diverticulum presenting with combined bowel and urinary obstruction and mimicking Crohn’s disease: a case report" doc
Ngày tải lên :
11/08/2014, 07:20
... reports of patients with Meckel s diverticulum masquerading as Crohn s disease are rare [12], but cases of patients with Meckel s diverticulum associated with confirmed Crohn s disease are not uncommon ... of the case Due to the lack of ectopic gastric mucosa in the resected specimen, the scan would not have assisted in diagnosis even if performed Laparoscopy did not lead to the diagnosis due to ... no other obvious abnormalities were seen to support a diagnosis of Crohn s disease or malignancy Fecal diversion was deemed unnecessary because the perforated Meckel s diverticulum was felt to...
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Báo cáo y học: "Acute panuveitis with hypopyon in Crohn''''s disease secondary to medical therapy: a case report." pptx
Ngày tải lên :
11/08/2014, 10:22
... uveitis occurs in approximately 4% of patients with Crohn' s disease Presentation with hypopyon is unusual and raises suspicion of either alternative systemic inflammatory disorders such as Behỗet 's ... increase frequency of uveitis, this could explain the acute onset of uveitis in our case[10] Conclusion The use of rifabutin to treat Crohn' s disease is controversial and is currently used on ... Ocular manifestations of inflammatory bowel disease Inflammatory bowel diseases 2004, 10(2):135-139 Duker JS, Brown GC, Brooks L: Retinal vasculitis in Crohn' s disease American journal of ophthalmology...
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Báo cáo y học: "Granulomatous cheilitis associated with exacerbations of Crohn''''s disease: a case report" potx
Ngày tải lên :
11/08/2014, 11:20
... granulomatus cheilitis should be carefully asked about the presence of gastrointestinal symptoms Those with suspicious symptoms should have a careful gastrointestinal evaluation, including enteroclysis ... involvement of the terminal ileum in a total length of 50 cm Administration of meth- Figure disease Crohn' s picture of the patient 's lip before the diagnosis of Histological Histological picture of the ... patient 's lip before the diagnosis of Crohn' s disease Multilayer squamous epithelium covering the tissue specimen, scattered clusters of lymphocytes and histiocytes resembling non-caseating granulomas,...
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Báo cáo y học: "Colonic adenocarcinoma revealing Crohn''''s disease: a case report Case report" pdf
Ngày tải lên :
11/08/2014, 12:20
... abdominal scan showing the sigmoid process ation or the prevalence of Crohn' s disease in Morocco However, a north -to- south gradient could be observed The association between Crohn' s disease and ... conditions has been suggested by the clinicopathological data obtained from over 150 case reports [6] The extent of this association has been assessed by incidence studies comparing the risk of colon ... evaluated the surveillance for colorectal cancer in Crohn' s disease This study, which was undertaken in 356 patients using rectal biopsies, showed that dysplasia Figure Photograph of the surgical specimen...
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báo cáo khoa học: " Musings on genome medicine: Crohn’s disease" potx
Ngày tải lên :
11/08/2014, 12:20
... antigens responsible for CD and UC are currently unknown, both illnesses are considered ‘auto immune’ diseases, as are multiple sclerosis, psoriasis, rheumatoid arthritis, juvenile diabetes mellitus ... risk factor gene Clearly, delineation of the genetic basis of CD requires considerably more study As emphasized above, it also remains possible that most of the risk is not inherited but is instead ... morphisms of the genes that control autophagy, phago some assembly, the so-called inflammasome, interleukin 23 receptors, epithelial barriers, Paneth cells of the gut, the NFkB/IRF system, and other...
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Báo cáo y học: "A 47-year-old man with neuro-Sweet syndrome in association with Crohn’s disease: a case report" ppsx
Ngày tải lên :
11/08/2014, 14:20
... cyclosporine and dapsone Conclusion This is a case of aseptic meningitis secondary to neuroSweet disease in a patient with Crohn s disease The association of Crohn s disease with Sweet s syndrome ... was previously described in the literature This is the first case, to our knowledge, of the association of neuro-Sweet disease with Crohn s disease Because of its multisystem nature, Sweet s syndrome ... findings supported the clinical diagnosis of acute neutrophilic dermatosis (Sweet s disease. ) On days 4-6 of admission, his symptoms started to improve He was still having headaches and spiking...
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Báo cáo y học: "Sweet''''s syndrome in a patient with Crohn''''s disease: a case report" pot
Ngày tải lên :
11/08/2014, 21:22
... colitis and Crohn' s disease is well established Sweet 's syndrome can be distinguished from pyoderma gangrenosum by the absence of vasculitis and lack of dermal necrosis, but histological features may ... malignancies [7] Other causes of Sweet 's syndrome are listed in table Only a few cases of Sweet 's syndrome associated with Crohn' s disease have been reported in the literature [1] There is a higher ... inflammatory diseases that accompany Crohn' s disease, like erythema nodusum, pyoderma gangrenosum and leukocytoclastic vasculitis Awareness of this association may guide appropriate diagnostic procedures...
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Báo cáo y học: " Takayasu''''s arteritis associated with Crohn''''s disease: a case report" pot
Ngày tải lên :
11/08/2014, 23:21
... Granulomas and granulomatous vasculitis are seen in both CD and TA Granulomatous vasculitis shows a common pathophysiology in both diseases [6] Location of the lesion and sometimes the age of the ... clinical course of patients with IBD [6] Conclusion Takayasu 's arteritis affects the aorta and its vasculature and may compromise intestinal vessels Therefore, it may present with gastrointestinal ... and its vasculature, TA may present with gastrointestinal bleeding [6] Since most of these features may also be present in CD, there might be a diagnostic dilemma when there is presentation of both...
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Báo cáo y học: "Chronic cough associated with Crohn’s disease" pdf
Ngày tải lên :
13/08/2014, 10:20
... significant respiratory manifestations of IBD are uncommon [2,3] Any part of the lung and its vasculature may be involved in association with IBD Large airways disease is the commonest site of lung involvement ... Interestingly flare up of bronchiectasis has been observed within a year following colectomy [4,5] This transfer of the inflammatory process from the gastro intestinal tract to the lungs has been suggested ... review these accounted for 39% of the cases of which two thirds comprise bronchiectasis Bronchiectasis is most commonly observed in UC, predominates in women and more common in non-smokers Interestingly...
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báo cáo hóa học: " Serum antibodies from Parkinson''''s disease patients react with neuronal membrane proteins from a mouse " ppt
Ngày tải lên :
19/06/2014, 22:20
... scoreWestern analysis (Fig 2) Correlation analysis of clinical score (UPDRS – total) with the sum of the peak areas from the Western analysis (Fig 2) The r2 value was assessed by linear regression ... analysis of the viability of these cells revealed that the observed reductions in DA levels within these co-cultures were not due to the viability of these cells (data not shown) Analysis of the ... binding of antibodies to certain MN9D antigens, which are less expressed in the non-treated MN9D cells since they were not affected by the IPD sera in the absence of N9 cells This positive signal may...
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