... Svend, Erik Olsen. Psychology interaction and
pragmatic linguistics. - In: Pragmalingui-
stics, The Hague, 1979.
276
THE ~ OF OOM~K/NICATIVE CONYEXrOFDIALOGUEINTERACTION
A.S. Narin'yani, ... about the
world. State of M at moment z (i.e. M ) is a
consistent subset of propositions from {~}, each
of which being characterized by index of certainty.
The machinery ofinteraction between ... considered as system of three auto-
mata representing the partners of the dialogue and
enviror~ent.
The o~l,nunicative cc~tence of the partners is de-
fined by
- the set M of all propositions...
... Drug Application
ORA Office of Regulatory Affairs
ORO Office of Regional Operations
OSD Office of the Secretary of Defense
PB pyridostigmine bromide
PEO Program Executive Officer
PHSA Public Health ... recognized in the official United States Pharmacopoeia, official Home-
opathic Pharmacopoeia of the United States, or official National Formulary, or any
supplement to any of them; and (B) articles ... Matter of Perspective 3
Background 4
Organization of the Report 7
Research Methods 8
Chapter Two
THE CHALLENGES OF ACQUISITION 11
Licensing 12
The Department of Defense’s Organization for
FDA Interaction...
... cycles of steepest descent
followed by 50 cycles of conjugate gradients and 50 cycles
of steepest descent). No clashes were detected at the dimer
interface of the models or in the surroundings of ... carboxylates of residues
Asp38 and Glu111. In RNase-AA-GG the ‘basic sur-
face’ is more similar to that of BS-RNase because of
the removal of the four carboxylates. The ‘basic sur-
face’ of the mutant ... shows the shape of the electrostatic
field of BS-RNase seen from different directions.
Figure S3 compares the electrostatic field of different
Fig. 5. Plot of the EIE values as function of rotation...
... downstream of the first 88
amino acids of PPI1 may participate in the interaction
with the H
+
-ATPase and makes PPI1
588
His
6
a suitable
tool to study the mechanism of action of PPI1.
The analysis of ... novel interaction partner for the C-termi-
nus of Arabidopsis thaliana plasma membrane H
+
-ATP-
ase (AHA1 isoform): site and mechanism of action on
H
+
-ATPase activity differ from those of 14-3-3 ... that the site ofinteraction with
the PM H
+
-ATPase was localized in the N-terminus
of PPI1. To further characterize the biological activity
Fig. 4. pH dependence of the activation of A. thaliana...
... and gathering of information in
e.g. social dialogue. In the latter category of dia-
logue systems, a high level of naturalness of interac-
tion and the occurrence of longer periods of satisfac-
tory ... Example dialogue.
3.1 Dialogue state/action management
The dialogue state is unique at every stage of
the conversation and is represented as a vector of
feature-values. We use only a limited set of ... inclusion of a personal questionnaire for re-
lation building at the beginning of the dialogue and
a commitment question at the end of the dialogue.
Another difference was the more restricted use of
the...
... between COMM UN ICATOR dialogue actions
and in-car dialo gue actions, for each sub-task type of
the in-car system.
121
An ISU Dialogue System Exhibiting Reinforcement Learning of Dialogue
Policies: ... Henderson
School of Informatics
University of Edinburgh
olemon@inf.ed.ac.uk
Matthew Stuttle
Dept. of Engineering
University of Cambridge
mns25@cam.ac.uk
Abstract
We demonstrate a multimodal dialogue ... (ISU) dialogue system to exhibit rein-
forcement learning ofdialogue strategies, and
also has a fragmentary clarification feature.
This paper describes the main components and
functionality of the...
... nature of the interactionof zinc with GDH, we
have thoroughly investigated the effect that variation
of the amino acid substrate concentration has on the
ability of zinc to inhibit the activity of ... observed.
Effects of zinc on the stability of the enzyme
The thermal stability of the enzyme was determined
using differential scanning calorimetry in the presence
and absence of zinc under a variety of conditions. ... maximal
activity of the enzyme, thus resulting in a potent inhi-
bition of the overall maximum rate of the oxidative
deamination of
L-glutamate. This further emphasizes
the vital role that subunit–subunit interactions...
... greater detail below.
Instability of the mutant enzyme
Further analysis of the kinetic parameters of the G167E
mutant was hindered by rapid inhibition of the activity of
the bc
1
complex during the ... concentrations of > 40 l
M
(Fig. 4A) may be a
result of the weakly chaotropic nature of the substrate
and the inherent partioning of quinol into the Q
o
site. The
Fig. 3. Steady-state level of the ... mitochondria. Studies of the mechanism of assembly
of the bc
1
complex suggest that the ISP is one of the last
subunits to be integrated within the membrane-bound
subcomplex [2]. The integration of the ISP...
... parts
of the N-terminal fragment and ⁄ or the second cassette;
AB
DC
EF
Fig. 5. Effects of point mutation of the
WalkerA and B motifs of the AAA-cassettes
of Pex6p on the morphological appearance
of ... point
mutations in WalkerB of D2 in both AAA-peroxins
AB
DC
EF
Fig. 4. Effects of point mutation of the
WalkerA and B motifs of the AAA-cassettes
of Pex1p on the morphological appearance of
peroxisomes. ... binding sites and elucidated the
importance of ATP-binding and -hydrolysis of Pex1p and Pex6p for their
interaction. We show that the interactionof Pex1p and Pex6p involves
their first AAA-cassettes...
... date, mapping of the interaction site of CP12
had not studied but our results give some clues with
regard to the binding of CP12 to GAPDH. The impact
of CP12 binding on the activity of GAPDH is ... dissociation
was observed with the A
8
B
8
isoform of GAPDH lead-
ing to the A
2
B
2
isoform with a higher NADPH-
dependent activity [39].
By analogy with the CTE of the isoform of GAPDH
[15,37], we hypothesize ... occurs.
The interaction site might thus be present at the
level of this fragment of molecular mass of 2347 Da
(residues 26–48), corresponding to the central part of
CP12. Moreover, fragments of high...
... RW, Seidel JC & Gergely J (1971) The stochio-
metry of the reaction of the spin labeling of F-actin and
the effect of orientation of spin-labelled F-actin fila-
ments. Arch Biochem Biophys ... This geometry
minimized distortion of the signal due to incomplete alignment of
F-actin filaments. (B) shows the spectra of filaments of F-actin with
three sorts of cross-links: (a) interstrand cross-links ... Morales MF (1971) Interactionof globular
actin with myosin subfragments. J Mol Biol 60, 249–
261.
17 Pope D, Lednev VV & Jahn W (1987) Methods of pre-
paring well-oriented sols of F-actin containing...
... necrosis factor-a production (Fig. 10).
The comparison of the results of the interactionof LPS
with HDL to those published for the interactionof the
former with another serum protein, albumin, ... cm
)1
(Fig. 2). These
values are indicative of acyl chains with a large amount of
gauche conformers. Importantly, the interactionof HDL
with LPS leads to a reduction of the wavenumber by more
than one ... sugar
units, lipid A two of each) which may be connected with
different conformations of the molecules.
Differential scanning calorimetry measurements of the
interaction of LPS with HDL (Fig. 3)...
... intensities of the NOE
connectivities are indicated by the widths of the stripes.
Ó FEBS 2002 Mode ofinteractionof lytic peptides (Eur. J. Biochem. 269) 3873
Structures and mode of membrane interaction ... Jelinek
2
1
Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel;
2
Department of Chemistry, Ben Gurion
University of the Negev, Beersheva, Israel
The interactionof many lytic ... Mode ofinteractionof lytic peptides (Eur. J. Biochem. 269) 3875
The results of the FTIR study in PtdCho/cholesterol and
PtdEtn/PtdGro membranes [19] have revealed that the
majoramideIbandofK
4
L
3
l
4
Wislocatedat%...
... task and dialogue initiatives,
and present a model for tracking shifts in both
types of initiatives in dialogue interactions.
Our model predicts the initiative holders in the
next dialogue ... agent may take over the dialogue
initiative but not the task initiative, as in (3b) above.
2.2 An Analysis of the TRAINS91 Dialogues
To analyze the distribution of task /dialogue initiatives
in ... dialogues, we annotated the
TRAINS91 dialogues (Gross, Allen, and Traum, 1993)
as follows: each dialogue turn is given two labels, task
initiative (TI) and dialogue initiative (DI), each of...