concentrations of smoke toxicants in cigarettes and in human smokers

Báo cáo khoa học: "Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients" doc

Ngày tải lên : 09/08/2014, 09:21

... activates other MSPs and MMPs [8,9] TATI is a trypsin inhibitor that balances concentrations of trypsin and also functions as a weak inhibitor of other serine proteinases [10,11] In addition, TATI ... concentrations and s-creatinine, this could in part be explained by an impaired renal function in elderly patients, which is in line with previous findings demonstrating an association between increased ... concentrations in tumour tissue, normal mucosa, and serum in relation to radiotherapy In line with previous findings [1], TATI expression in tumour cells was variable and less abundant than in...

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Báo cáo khoa học: "Concentrations of cardiac Troponin I before and after ovariohysterectomy in 46 female dogs with pyometra" pdf

Ngày tải lên : 12/08/2014, 18:22

... increases in cTnI appears to be common in dogs with pyometra before and after surgery, but the clinical importance of this finding is uncertain None of the studied clinical variables (including ... release endotoxin during growth or when they die [26] Endotoxins bind to receptors on cell-membranes and induce inflammation and cytokine production [26] Depending on the extent of endotoxin release, ... Bacterial toxins in the veterinary clinic [Bakterielle toksiner i den veterinaere klinik] Dansk veterinaertidskrift 1992, 75:809-815 (In Danish) Fransson BA: Systemic inflammatory response in Canine Pyometra...

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Báo cáo y học: "Serum concentrations of cortisol, interleukin 6, leptin and adiponectin predict stress induced insulin resistance in acute inflammatory reaction" pot

Ngày tải lên : 13/08/2014, 11:23

... al interleukin (IL)6 activate signalling cascades including nuclear factor B (NF-B) and C-Jun N-terminal kinases (JNK), which inhibit insulin signalling by serine phosphorylation of insulin ... of different mediators of insulin resistance we have performed kinetic studies in an acute inflammatory setting in humans Inflammation caused by cardiac surgery increased insulin resistance in ... mononuclear cells in humans and stimulated in an inflammation dependent manner [36] This prompted the hypothesis of resistin being a prominent mediator of inflammatory insulin resistance in humans, which...

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Effect of poverty on the relationship between personal exposures and ambient concentrations of air pollutants in ho chi minh city

Ngày tải lên : 13/09/2015, 17:48

... field and lab staff carried out routine quality assurance checks, including the collection of blank 155 and duplicate samples, balance stability testing in the laboratory, and use of blanks and ... participants reported current smoking, 60 reported spending time 208 in the presence of smokers and among those the average time of secondhand smoke exposure was 48 209 minutes per day There were few ... during the sampling campaign with mean and standard deviation (sd) of ppb (sd= 1.4 ppb) and 0.74 ppb 222 (sd =0.7 ppb) leading to a limit of detection (LOD) of 5.2 and 2.8 ppb for personal and...

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Tài liệu Báo cáo Y học: Regulated expression and intracellular localization of cystatin F in human U937 cells pptx

Ngày tải lên : 21/02/2014, 01:21

... cystatin F, through analysis of the expression, distribution and properties of the native human inhibitor in U937 cells MATERIALS AND METHODS In silico cloning and sequencing of the human cystatin ... in the ER staining where cystatin F stains Regulation of cystatin F expression To shed light on the regulation of the cystatin F gene, we examined the sequence of the human gene, CST7 At an initial ... characterization and use of monoclonal antibodies against the major extracellular human cysteine proteinase inhibitors cystatin C and kininogen Scand J Clin Laboratory Invest 48, 573–582 Bjarnadottir,...

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Báo cáo khóa học: O-acetylation and de-O-acetylation of sialic acids in human colorectal carcinoma docx

Ngày tải lên : 07/03/2014, 14:20

... found in porcine and bovine submandibular glands [9,21], is regulated by the relative activity of cytosolic OAE Materials and methods Patient samples Tissue was obtained from patients undergoing ... described in Shen et al [11] Brieﬂy, OAT activity measured using endogenous substrates was performed by incubating 50 lg of protein in 30 lL of 50 mM potassium phosphate buffer, pH 7.0, containing ... observed in studies utilizing a series of human colorectal carcinoma cell lines [7] and tissue obtained from colorectal cancer patients [3,7] The level of mono-Oacetylated Neu5Ac (Neu5,9Ac2 and Neu5,7Ac2)...

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Báo cáo khoa học: Identiﬁcation and characterization of multiple species of tenascin-X in human serum doc

Ngày tải lên : 23/03/2014, 09:21

... previously mapped binding of these proteins to the FNIII29 of TNX in a study of C-terminal TNX domains [20] The recombinant TNX domains in our previous study were produced in prokaryotic cells ... and Physiology of the Washington University School of Medicine are acknowledged for performing N-terminal sequencing and providing recombinant tropoelastin Claire Lethias of the Institut de Biologie ... significant binding to human collagen type I, III and V; binding to human fibronectin, laminin or irrelevant protein (BSA) was also absent (data not shown) Similarly, we did not find any effect of serum...

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Báo cáo khoa học: Characterization of sequence variations in human histone H1.2 and H1.4 subtypes pptx

Ngày tải lên : 30/03/2014, 20:20

... tail and the binding of H1.4 to chromatin, as arginine offers additional hydrogen-bonding abilities to DNA as compared to lysine Lysine 173 in H1.4 is situated in an SPKK motif, one of the known ... believed to be involved in positioning of the globular domain on the nucleosome [32] The N- and C-terminal tails of histone H1 adopt a random coil in solution [33] On binding of histone H1° to DNA, ... the binding of H1.2 to chromatin, may be affected A further nonsynonymous substitution prompted the replacement of lysine with arginine in the C-terminal tail (position 173) of histone H1.4 in...

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Báo cáo y học: " CD39+ Regulatory T cells suppress generation and differentiation of Th17 cells in human malignant pleural effusion via a LAP-dependent mechanism" pps

Ngày tải lên : 12/08/2014, 13:22

... Servant, R Zollinger, SI Bogiatzi, P Hupé, E Barillot, V Soumelis, A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 ... Cells in MPE We determined some cytokines that reported be involved in generation and differentiation of Tregs or Th17 cells, and observed that high levels of IL-1b, IL-6, and TGF-b1, but not of ... http://respiratory-research.com/content/12/1/77 Page of 10 Figure Proinflammatory cytokines increased in malignant pleural effusion (MPE) Comparisons of concentrations of IL-1b (A), IL-6 (B), IL23 (C), and TGF-b1 (D) in both MPE and sera...

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Báo cáo y học: "Systematic analysis of gene expression in human brains before and after death" docx

Ngày tải lên : 14/08/2014, 16:20

... expression patterns in postmortem human brains Study of expression levels of 14 genes in human brain autopsy and biopsy samples found significant change in one of the genes, indicating that a substantial ... organization and biogenesis' and 'intracellular protein transport' (Table 2) The expression of genes involved in the ubiquitin cycle and protein ubiquitination is significantly increased after ... translated to functional proteins, up-regulation of genes involved in ubiquitin-dependent protein catabolism may lead to increased degradation of proteins in human brain samples after death This...

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Actual situation study, some factors has risk to infect larva of toxocara canis in human and effect of treatment by albendazole at 2 commune of an nhon district, binh dinh province (2011 2012)

Ngày tải lên : 29/10/2014, 22:17

... roundworm larvae in human; in dogs, in surroundings (soil) 2.2.6 Use definitions and concepts in research: The infection ratio of dog roundworm larvae in human; in dogs, in surroundings (soil); ... prior to interviewing, investigating and interviewing cadres must be trained and a trial interview will be made in the locality 2.2.8 Parameter handling: collected parameters will be handled by ... (36.0%) and having habit of eating fresh vegetable (26.0%) [30] According to P.A.M Overgaauw and et at (1997), no increase of morbidity rate of larvae of Toxocara canis in those working in veterinary...

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the role of raft domains in human red blood cell transmembrane signaling and membrane cholesterol transport

Ngày tải lên : 13/11/2014, 10:36

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Development of a robotic nanny for children and a case study of emotion recognition in human robotic interaction

Ngày tải lên : 09/09/2015, 10:18

... Corporation It has 38 DOFs, standing 58cm, and can fulﬁll motion and communication entertainment There are two main entertainment abilities in SDR-4X, which are dancing and singing When singing a song, ... during singing a song 63 3.18 The ﬂowchart of playing music video function 64 3.19 The sub-interface of chatting with a child 65 3.20 The sub-interface of video calling ... pioneering work was Darwin in 1872 [51] who referred to the universality and continuity of facial expressions in man and animals, and stated the relationships between some inborn emotions and serviceable...

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Experimentation, modeling and control of calcium dynamics in human vascular endothelial cells

Ngày tải lên : 09/09/2015, 18:48

... identifying the structure of the mechano-sensor in VECs membrane, ﬁnding signaling pathway given certain type of mechanical stimulus and investigating the interplay of gene expression and cell ... biological/physiological and engineering perspectives Proﬁcient skills in handling cells and chip In our case, we need to integrate cell culture, ATP release measurement and Ca2+ imaging into the one system The main ... concentration of ATP on cell surface, in uencing calcium mobilization in an indirect fashion In the meanwhile, there were several other groups providing their results supporting Ando’s point of view...

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Exploration of the functional significance of mig 2 in human cancer cell susceptibility to cytotoxic agents and cell growth control a pilot study

Ngày tải lên : 05/10/2015, 22:15

... proteins ECM binding initiates clustering of integrins in the plane of the membrane and reorganization of the actin cytoskeleton, which further stimulates the organization of integrins and associated ... domain and FERM domain Interestingly, the sequence analysis revealed the similar filopodin and erin/radixin/moesin (FERM) domain and pleckstrin homology (PH) domain structures in mig-2 gene and ... regulated in patients with Kindler syndrome, an autosomal recessive skin disorder They therefore defined a family of kindlin-related proteins namely Kindlin-1, Kindlin-2 (mig-2) and Kindlin-3 (Siegel...

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Effects of Electrical Current in Human Body

Ngày tải lên : 31/08/2012, 16:33

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Introduction of Who Believes in Human Rights

Ngày tải lên : 01/11/2013, 10:20

... would not have been alone in this view Douzinas writes of the bureaucratization of human rights: ‘Official thinking and action on human rights has been entrusted in the hands of triumphalist column ... equalisation of rights (the building blocks of every positivism) and human rights, which are the promises of a future and the critique of all positive law and system of rights’: Douzinas, End of Human ... diplomats and rich international lawyers in New York and Geneva, people whose experience of human rights violations is confined to being served a bad bottle of wine In the process, human rights...

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Báo cáo khoa học: Internalization of cystatin C in human cell lines docx

Ngày tải lên : 16/03/2014, 06:20

... protease, legumain, because of removal of the key amino acid in the legumain-binding site of cystatin C [22] The amino acid substitutions reside in opposing parts of the cystatin C molecule, which ... of the endogenous cysteine proteinases, the cysteine protease inhibitory capacity of the cell lysate was determined by measuring the inhibition of (A) papain and (B) cathepsin B As positive and ... Papain and cathepsin B inhibition The cysteine protease inhibitory capacity in cell lysates was determined by measuring the inhibition of papain as well as cathepsin B To measure the capacity of...

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Báo cáo khoa học: Identiﬁcation of a novel alternative splicing variant of RGS5 mRNA in human ocular tissues ppt

Ngày tải lên : 23/03/2014, 13:20

... proteins T, total protein; M, membrane protein; C, cytosolic protein Arrows indicate a 26 kDa protein of RGS5 and a 13 kDa protein of RGS5s 794 -10 Fig Effects of RGS5 and RGS5s on Ca2+ signaling ... alternative splicing occurred at both 5¢ and 3¢ regions generating four alternative isoforms encoding four distinct N-terminal domains and three distinct C-terminal domains [23] These intramolecular ... deletion of RGS8 resulted in a remarkable decrease in the inhibitory effects of RGS8 on Gaq-coupled responses The nine amino acids in the N-termini of RGS8 were determined to be important for the inhibition...

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Expression pattern of matrix metalloproteinases in human gynecological cancer cell lines ppt

Ngày tải lên : 28/03/2014, 14:20

... as mRNA and protein Further, mRNAs and proteins of MMP-2, -9, -15 and -23 were moderately expressed in this cell line According to this finding we also detected gelatinolytic activity of secreted ... carcinomas corresponds to our finding of strong mRNA expression in Caski and SiHa cell lines [13] Further, we found a strong expression of MMP-15 mRNA in those cell lines These results are in line ... expression of MMP-2 and -9 and progression of endometrial carcinoma was detected by Di Nezza et al using in situ hybridization and in situ zymography MMP-2, -9 and -14 were mainly localized in epithelial...

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