communications signaling systems data systems fire protective signaling systems and systems less than 120 volts nominal
Báo cáo y học: "Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages" pot
Ngày tải lên :
14/08/2014, 07:21
... 1eup) binding site Two androstenedione molecules (Andro1 and Andro2 colored in blue and purple, respectively) are bound to the protein The binding site (in spacefill) for the androstenedione is divided ... of one androstenedion (Andro2) induces conformational changes in the active site and increases its hydrophobicity, resulting in increased binding affinity to the other androstenedion (Andro1) ... protein modularity and tables with the data sets used for the analyses Click here examples for the analyses file Additionalfor file of protein modularity and the datasets used analyses data This project...
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Báo cáo khoa học: Cotton GhMPK2 is involved in multiple signaling pathways and mediates defense responses to pathogen infection and oxidative stress doc
Ngày tải lên :
14/03/2014, 23:20
... as hormone signaling, biotic and abiotic stress responses, and development [15,16], whereas high concentrations of ROS can result in oxidative stress and cause irreversible damage and hypersensitive ... involved in various signaling processes and have unique biological functions Cotton (Gossypium hirsutum) is one of the oldest and most important fiber and oil crops Its growth and yield are severely ... healthy and fully expanded tobacco leaves of wild-type and transgenic plants at the same age The disks were floated in solutions of various concentrations of MV (0, and 10 lm) for 72 h, and then...
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Báo cáo khoa học: Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase pptx
Ngày tải lên :
28/03/2014, 23:20
... cartilage [12], and other peripheral tissues, and plays a variety of local regulatory roles The physiological and pathophysiological roles of natriuretic peptides and receptor systems are reviewed ... Receptor guanylate cyclase structure and signaling A Fig (A, B) Crystal structures of the apoECD dimer (Protein Data Bank: 1DP4) and the ANP–ECD complex (Protein Data Bank: 1T34) [17,34] ANP is shown ... state-stabilizing arginine, and triphosphate-binding arginine and lysines [79] The guanine base-recognition residues glutamic acid and cysteine in Cyg12 [79] and glutamic acid and glycine in Cya2 [80]...
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Báo cáo khoa học: Signaling pathways and preimplantation development of mammalian embryos potx
Ngày tải lên :
30/03/2014, 03:20
... activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling Cell 94, 109–118 72 Habas R, Dawid IB & He X (2003) Coactivation of Rac and Rho by Wnt ⁄ Frizzled signaling ... kinase)-1, -2, -5, and MAPK ⁄ ERK1 are detected in unfertilized eggs and blastocysts Transcripts and the protein localization of p38-regulated and -activated kinase, p38 MAPK, MK2 and hsp25 have ... detected in blastocysts, and Wnt1 and -4, Sfrp1 and Dkk1 are highly expressed at this stage [37] Receptors (Fz2, frizzled-2 and Fz4, frizzled-4), intracellular signal transducers and modifiers [Dishevelled...
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cancer cell signaling methods and protocols
Ngày tải lên :
10/04/2014, 11:11
... vol 218: Cancer Cell Signaling: Methods and Protocols Edited by: D M Terrian © Humana Press Inc., Totowa, NJ Knudsen and Angus has been identified based on linkage analysis and subsequent epidemiological ... Transfection Use µg of CMV-vector or CMV-RB and 0.5 µg of CMV-H2B-GFP (see Note 5) Use 0.25 mL CaCl2 and 0.25 mL 2X BBS 10 Knudsen and Angus 3.3.3 Cell Harvesting and Fixation 36–48 h after adding fresh ... wish to thank Dr George Babcock and Sandy Schwemberger (Shriners Hospital for Children, Cincinnati, OH) for expert flow cytometric analysis References Knudson, A G (1993) Antioncogenes and human...
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g protein signaling, methods and protocols
Ngày tải lên :
10/04/2014, 22:24
... subunits and effectors Biochemistry 39, 11,340–11,347 26 Posner, B A., Gilman, A G., and Harris, B A (1999) Regulators of G protein signaling and Purification of complexes with Gβ5 and assessment ... µL each of digested and cleaned insert and vector and load onto a 1.0% agarose gel, without ethidium bromide, and run at 50 V for 2–3 h to obtain maximum separation of DNA bands Stain gel in 50 ... Efforts to solubilize and/ or refold Gα associated with the particulate fraction have not been successful Wild-type and mutant forms of Gsα, Giα1, Giα2, Giα3, and Goα are soluble and easily purified...
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Cancer Cell Signaling Methods and Protocols potx
Ngày tải lên :
29/06/2014, 06:20
... Pathogens: Methods and Protocols, edited by Konrad Sachse and Joachim Frey, 2003 215 Cytokines and Colony Stimulating Factors: Methods and Protocols, edited by Dieter Körholz and Wieland Kiess, 2003 ... Methods and Protocols, edited by Tanja Zigova, Juan R Sanchez-Ramos, and Paul R Sanberg, 2002 197 Mitochondrial DNA: Methods and Protocols, edited by William C Copeland, 2002 196 Oxidants and Antioxidants: ... Bing-Yuan Chen and Harry W Janes, 2002 191 Telomeres and Telomerase: Methods and Protocols, edited by John A Double and Michael J Thompson, 2002 190 High Throughput Screening: Methods and Protocols,...
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Báo cáo sinh học: "Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists." pps
Ngày tải lên :
06/08/2014, 18:20
... by the labs of Andrew McMahon and Matthew Scott We thank James Chen and Phillip Beachy for providing us with KAAD-cyclopamine and for sharing their observations that cyclopamine and its derivatives ... of these compounds Data points represent the averages (n = 2) with standard deviations less than 15% (e) Structures of Hh-agonist derivatives; 1.2 is a methylated analog, and 1.3 a methylated ... as potent in signaling assays (EC50 M) as its Ki (96 nM) might predict This suggests an uncoupling of binding and signaling for certain agonists Although binding affinities and signaling efficacy...
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Báo cáo y học: " The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages" doc
Ngày tải lên :
11/08/2014, 08:22
... pro-inflammatory cytokines and inhibit iNOS expression and NO release in LPS-stimulated RAW264.7 macrophages by targeting the NFB activation pathway Materials And Methods Cell Culture and Sample Treatment ... anti-IKBa and anti-actin Bar graphs represent the quantitative densitometric value of the expressed protein vs actin: pIKBaser32/36 h (B) and h (E), IKBa- h (C) and h (F) *p < 0.05 vs LPS Data shown ... curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages Biochem Pharmacol 2000, 60:1665-76 Kabe Y, Ando K, Hirao S, Yoshida M, Handa...
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Báo cáo y học: "Protein degradation, signaling, microRNAs and cancer" ppsx
Ngày tải lên :
14/08/2014, 14:21
... Scylla and Charybdis These two function in the insulin pathway downstream of PI 3-kinase and the protein kinase (and certified proto-oncogene) Akt/PKB and upstream of the tumor suppressors TSC1 and ... protein family appears to lie at the intersection of two important and evolutionarily conserved signaling pathways, the hypoxia-induced and the insulin pathway Turning from the control of size to the ... identified components Legless/Bcl-9 (Lgs) and Pygopus (Pygo) not exclusively serve to localize the transcription factor β-catenin/Armadillo to the nucleus in response to Wnt signaling, but also themselves...
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Báo cáo y học: "The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like β-grasp domains" pps
Ngày tải lên :
14/08/2014, 16:21
... the GTP precursor (MoaA and MoaC); the MoeB, MoaD and MoaE products, which are downstream of the former and involved in molybdopterin biosynthesis; and MoeE, MogA, MobD, and the MOSC domain proteins, ... prokaryotic systems with components related to eukaryotic to ubiquitinsignaling network sions involved in thiamine and MoCo/WCo biosynthesis and majority of other predicted operons (Table and Figure ... ubiquitin-like signaling system, and we suggest that these systems were the precursors to the eukaryotic Ubsignaling system We hope this report may stimulate experimental analysis of these bacterial systems...
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lte signaling troubaleshooting and optimization
Ngày tải lên :
27/10/2014, 00:56
... Troubleshooting and Optimization Structure of IMEISV (according to 3GPP 23.303) Reproduced with permission from © 3GPP™ Table 1.2
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characterization of signaling pathways and significance of the axon guidance molecule plexin b3 in glioma progression
Ngày tải lên :
11/09/2015, 09:11
... scientifically and personally, for which I am very grateful Finally, I want to thank my family, my parents, my sisters, my husband and my son for all of their love and support Their daily encouragement and ... and neuropilins 1.1.3 Mechanism of semaphorin and plexin activation 1.1.4 Co-receptors: c-Met and Ron, ErbB2, Integrin and L1 11 1.2 Signaling pathways mediated by semaphorins and ... plexin-B3 and fascin-1 in human glioma cells161 5.6 Sema5A and plexin-B3 regulate fascin-1 distribution and actin cytoskeleton reorganization and induce cellular collapse in U-87 MG 163 5.7 Sema5A and...
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NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity
Ngày tải lên :
12/10/2015, 17:35
... 2003) ATM and ATR are at the central of DNA damage signaling pathways About 25 substrates of ATM and ATR have been identified, and many of them have been revealed as candidates in DNA damage signaling ... ATM- and ATR-mediated signaling pathways are highly interconnected ATM and ATR communicate with each other to coordinate and modulate the cellular outputs in respond to DNA strand breaks and stalled ... lab two and a half years ago, which I feel extremely lucky and fortunate Dr Wang’s enthusiasm to research and science infects me and motivates me all the time Her encouragement, patience and advices...
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NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity
Ngày tải lên :
26/11/2015, 22:49
... 2003) ATM and ATR are at the central of DNA damage signaling pathways About 25 substrates of ATM and ATR have been identified, and many of them have been revealed as candidates in DNA damage signaling ... ATM- and ATR-mediated signaling pathways are highly interconnected ATM and ATR communicate with each other to coordinate and modulate the cellular outputs in respond to DNA strand breaks and stalled ... lab two and a half years ago, which I feel extremely lucky and fortunate Dr Wang’s enthusiasm to research and science infects me and motivates me all the time Her encouragement, patience and advices...
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Changes of temperature data for energy studies over time and their impact on energy consumption and CO2 emissions. The case of Athens and Thessaloniki – Greece
Ngày tải lên :
05/09/2013, 16:10
... energy systems analysis, thermal and physical processes and equipment, internal combustion engines, utilization of renewable energy sources and de-pollution systems and technology for industrial and ... cooling demands is 28.5% and for Thessaloniki 13.2% Obviously, directly proportional to the energy demand for heating and cooling is the fuel (diesel oil) and electricity consumption and hence ... demand [1] or for estimating bin data and heating and cooling degree-days at any base [2, 10, 11] Table shows the monthly and yearly average ambient dry-bulb temperatures for the two cities and...
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Tài liệu Multiple Vulnerabilities qualitave data for the stydy of orpharns and vulnerable children in South Africa ppt
Ngày tải lên :
19/02/2014, 00:20
... violence (Standing, 2003; Anderson and Mhatre, 2003) Gender and domestic violence constitute a particular problem as the impact of this is felt directly in the homes and is witnessed and experienced ... unemployment and limited knowledge, due mainly to low standards of education and limited access to media Support systems for OVC The support systems for OVC include current government-based and NGO/CBO ... AIDS, and give handouts, you see So that when they came at home, they must re-touch on it What it’s done, you had to be honest, and that’s all The clinic talked about that, to give them handouts and...
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Tài liệu Báo cáo khoa học: "Learning with Unlabeled Data for Text Categorization Using Bootstrapping and Feature Projection Techniques" doc
Ngày tải lên :
20/02/2014, 16:20
... Using a Feature Projection Technique for Handling Noisy Data of Machine-labeled Data We finally obtained labeled data of a documents unit, machine-labeled data Now we can learn text classifiers ... related works, we presented two approaches using unlabeled data in text categorization; one approach combines unlabeled data and labeled data, and the other approach uses the clustering technique for ... training data Since our method depends on title words and keywords, we need additional studies about the characteristics of candidate words for title words and keywords according to each data set...
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Protective Equipment Studies and Research Projects pdf
Ngày tải lên :
09/03/2014, 00:20
... of their right hand and for left-handed persons to base their selection on the size of their left hand Hand measurements Shape: The shape of a hand corresponds to the dimensions and relative positions ... of the hand This affects the comfort and dexterity of the glove Dexterity: Dexterity is related to the skill, motion speed and control of the fingers and hands while handling objects Hand dexterity ... punctures and needle punctures When on duty and wearing his gloves, Claude must also be able to control and search a suspect, handle a can of pepper spray or handcuffs and, if necessary, use his firearm...
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Data Mining Association Analysis: Basic Concepts and Algorithms Lecture Notes for Chapter 6 Introduction to Data Mining pdf
Ngày tải lên :
15/03/2014, 09:20
... possible candidate itemsets Frequent Itemset Generation Brute-force approach: – Each itemset in the lattice is a candidate frequent itemset – Count the support of each candidate by scanning the database ... Used by DHP and vertical-based mining algorithms Reduce the number of comparisons (NM) – Use efficient data structures to store the candidates or transactions – No need to match every candidate ... Eliminate candidates that are infrequent, leaving only those that are frequent © Tan,Steinbach, Kumar Introduction to Data Mining 15 Reducing Number of Comparisons Candidate counting: – Scan the database...
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