common diseases in humans ppt
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 27) ppt
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... Springer-Verlag Berlin Heidelberg 2005
II.3.1 Phenothiazines
by Akira Ishii and Yoshinao Katsumata
Introduction
Phenothiazine drugs, including chlorpromazine and levomepromazine, have been being ... Poisoning due to psychotropic agents. Adverse Drug React Acute Poisoning Rev
4:83–126
3) Geraut A, Kintz P, Traqui A et al. (1994) Toxicological findings in a fatality involving chlorpromazine. ... distinct peaks.
However, peaks of perazine, prochlorperazine, thiethylperazine and perphenazine were small
and also interfered with by impurity peaks; low concentrations of these compounds in...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 28) pptx
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... Igarashi
Introduction
Butyrophenone drugs including haloperidol are being widely used in the eld of psychiatry.
e acute butyrophenone poisoning incidents sometimes take place; in such cases, ... solution, because it increases extraction e ciency due
to its salting-out e ect.
c) ere is a report using a haloperidol analog as IS, in which chlorine is substituted for the
uorine; but this ... temperature: 100 °C (1 min) → 30 °C/min →
270 °C (30 s) → 5 °C/min → 290 °C (5 min); injection temperature: 260 °C; separator tempera-
ture: 280 °C; carrier gas: He; its ow rate: 1.5 mL/min; MS ionization...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 29) ppt
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... carbamazepine obtained by GC/MS. A:
amitriptyline, B: mianserin, C: nortriptyline, D: imipramine, E: desipramine, F: promethazine (IS),
G: setiptiline, H: carbamazepine, I: maprotiline, J: clomipramine, ... also in-
cluded in this chapter.
GC/MS analysis
Reagents and their preparation
• Amitriptyline, carbamazepine, clomipramine, desipramine, imipramine, maprotiline, mi-
anserin, nortriptyline ... solvent can
be chosen according to the kind of a target drug.
e) Imipramine and amitriptyline are metabolized into desipramine and nortriptyline, respec-
tively, in a human body. Both metabolites...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 31) ppt
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... 5.1) contained in Wutt appears at 5.07 min under
the present HPLC conditions and thus can be an indicator of ingestion of Wutt.
In some analgesic-antipyretics, bromisovalum is also contained together ... hypnotics being sold as
over-the-counter drugs. Because of the easiness of getting it, bromisovalum is one of the most
important drugs in poisoning in Japan.
e analysis of bromisovalum is being made ... dissolved in 100 µL of the mobile phase, and a 10-µL aliquot is injected into
HPLC.
3.53.5
© Springer-Verlag Berlin Heidelberg 2005
II.3.5 Bromisovalum
by Keiko Kudo and Noriaki Ikeda
Introduction
Bromisovalum...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 32) ppt
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... of Vegetamin (a combined drug containing, phenobarbital, promethazine and
3.63.6
© Springer-Verlag Berlin Heidelberg 2005
II.3.6 Barbiturates
by Masaru Terada and Ritsuko Watanabe
Introduction
Barbiturates ...
are presented.
Incidence of fatal barbiturate poisoning cases. Since fatal cases due to Vegetamin® tablets
containing phenobarbital are many, its incidence rate is also shown in this figure.
⊡ ... female was found dead in her room; she had committed suicide
by injecting an alate needle into a vein of the right dorsum pedis for drop infusion of thiopen-
tal (its amount infused not clear)....
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 37) pptx
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... and antihistaminic drugs were administered intravenously. All drugs
for oral intake except phenytoin were discontinued on day 3 a er admission. e administra-
tion of phenytoin was also stopped ... phenytoin, and
theophylline. Wien Klin Wochenschr Suppl 191:27–31
5) Maya MT, Farinha AR, Lucas AM et al. (1992) Sensitive method for the determination of phenytoin in plasma,
and phenytoin and ... beta-blocking
drugs. Farmaco 55:136–145
Poisoning cases
4.54.5
© Springer-Verlag Berlin Heidelberg 2005
II.4.5 Antiepileptics
by Einosuke Tanaka
Introduction
As antiepileptics, phenytoin, mephenytoin,...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 38) pptx
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... relaxants in urine, serum and tissue homogenate can be extracted,
but especially suxamethonium (succinylcholine) is rapidly hydrolyzed in blood by the action of
cholinesterase; since it is ... dissolved in methanol just before use
a
.
• Synthesis of succinylmonocholine iodide [2]: 2.3 g choline iodide and 5 g succinic anhy-
dride are mixed and fused for reaction by heating the mixture ... for 1–2 h in an oil
bath. A er cooling to room temperature, the excessive (not reacted) succinic anhydride is
washed with 100 mL acetone, succinyl monocholine iodide is crystallized in the mixture...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 39) ppt
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... vessels; in the eye, they decrease
intraocular pressure by suppressing the production of aqueous humor. Since the drugs are also
e ective in suppressing muscle quivering and in suppressing overreaction ... GC/MS in the EI mode, intense fragment peaks can be de-
tected at m/z 284 and 129 for the isopropylamino drugs and at m/z 86 for the tertiary
butylamino drugs in common (
> Table 7.1). By using ... chromatograms for β-blockers extracted from urine of subjects, who had ingested each of
them. The results were obtained after single oral intake of each drug. In the analysis of atenolol,
double peaks...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 43) pptx
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... report describing the
di culty for detecting hypochlorite from blood of a victim, who committed suicide by ingest-
ing a bleaching agent [3].
Notes
a) Hypochlorite is very unstable in acidic aqueous ... alkaline or weakly acidic conditions to produce chloride ion together
with oxygen in the activated state, resulting in its bleaching action.
References
1) Yokogawa Analytical Systems (1999) Instruction ...
chlorate ions are contained. During preparation of the solutions and also during analysis, there
is a possibility of decomposition of the hypochlorite ion. As shown in
> Figure 1.1, the...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 46) pptx
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... Springer-Verlag Berlin Heidelberg 2005
II.5.4 Permethrin
by Naoto Matsumoto
Introduction
Pyrethroids are the general term for insecticide pyrethrins and their analogs ( cinerins and
jasmolins) ... present time.
Products containing pyrethroid insecticides are numerous; their toxicities for humans
are generally low. However, since phenotrin, permethrin and empenthrin are ubiquitous as
powders, ... ey are not only being used for household insecti-
cides, but also being used in agriculture worldwide. ey count about 1/3 of the total insecti-
cides, and are even increasing at the present...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 47) ppt
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... acid poisoning symptoms, nausea, vomiting, diarrhea and abdominal pain
is most common as observed in the above case; headache, scarlet fever-like exanthemas and
desquamation of the skin are sometimes ... (in Japanese)
2) Fukui S (1983) A method for determination of boric acid in foods using chelating extraction with 2-ethyl-1,3-
hexanediol and protonated curcumin. Eisei Kagaku 29:323–328 (in ... spectrophotometric analysis of boric acid in a urine specimen, the value
obtained may be slightly greater than the true value. is is probably due to interference by a
certain urinary element, which also...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 2) pptx
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... are being extended to
ultra-sensitive analysis of toxins in hair, nails, saliva and sweat; these specimens are proving to
be useful for toxin analysis, because many toxins are excreted into ... hair cells. e cells are keratinized during their growth.
rough this procedure, drugs and poisons are incorporated into hair, resulting in their stable
storage in it. e growth rate of hair ... secretion.
However, it should be kept in mind that during the change in the secretion rate, the amount of
a drug excreted into saliva may change according to changes in its pH [17].
A close relationship...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 6) ppt
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... matrices in which poisons were mixed, viz, drink in a
glass bottle, drink in a can, drink in a paper package, drink in a plastic bottle, drink in an un-
known container, tea in a pot, tea in a water ... Yoshioka
Introduction
In addition to the well known Tokyo Sarin Incident in 1995, the arsenic-adulteration incident
in Wakayama and the cyanide-adulteration incident in Nagano both in 1998 seem to ...
and melting point, are used as keywords for narrowing down toxins.
Database according to poisoning symptoms( assisting system for diagnosis of a causative toxin)
of subjects of studies being conducted...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 7) pptx
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... communication quality is being maintained to be able
to cope with the sudden outburst of a poisoning incident or accident; the complementary talks
are being refrained as possible. e mailing list is convenient ... point of August, 2001. A password is
given to each registrant to enable looking into the poisoning information part of HP of the
poison-net.
Analysis mailing list ( ml-anal)
In 1998, the Ministry ... made in the mailing lists
(ml-poison plus ml-anal)
e contents of talks made in both ml-poison and ml-anal were rearranged according to causa-
tive toxins, and shown in the “poisoning-talking...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 48) pptx
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... headspace vapor is withdrawn into the heated
syringe, and carefully injected into GC/MS not to in uence the vacuum degree of the MS
instrument.
iii. Detection is made using ions at m/z 128 for ...
volume vial a er heating at 80 °C for 30 min.
In this method, in spite of the use of a medium-bore capillary column in the splitless mode,
as much as 1 mL gas is injected into GC/MS. Usually, ... kept in mind that naphthalene is contained in gasoline, kerosene and heavy oil
[1] and also in tobacco smoke [2].
441Naphthalene
g) It is possible to make quantitation analysis without IS using...
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- some common diseases in humans
- common diseases in humans
- common diseases in humans list
- common diseases in humans caused by bacteria
- common eye diseases in humans ppt
- common bacterial diseases in humans ppt
- common viral diseases in humans ppt
- list of most common diseases in humans
- viral diseases in humans ppt
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