collagens structurally and functionally diverse proteins with common features

Báo cáo y học: "The AAA+ superfamily of functionally diverse proteins" ppsx

Ngày tải lên : 14/08/2014, 08:21

... fifth β-strand and contains an arginine finger that interacts with nucleotide bound by a neighboring subunit and is believed to play a role in ATP hydrolysis and intersubunit communication; and Boxes ... serve to define their lineage within the ASCE group as a whole, as well as within the AAA+ superfamily itself The defining features of the AAA+ proteins can all be found within a region of 200-250 ... serine, T is threonine, and x is any residue), lies between the first strand of the core β-sheet and the following helix, and plays an important role in nucleotide binding and metal-ion coordination...

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Báo cáo y học: "What makes species unique? The contribution of proteins with obscure features" pot

Ngày tải lên : 14/08/2014, 16:21

... R57.5 example, proline and serine), glutamine, and arginine and a lower content of aliphatic (for example, isoleucine and valine) and aromatic (tyrosine) amino acids, and aspartic acid (Table ... protein families with putative function [5,6] The distinction made in this paper between proteins with defined motifs or domains (PDFs), and those with undefined or obscure features (POFs) (Figure ... date, however, is an analysis of the origins and functions of genes encoding proteins that currently lack defined motifs or domains (proteins with obscure features (POFs)) [7,8] Expression profiling...

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Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulﬁde isomerase family proteins with nonclassic active center motifs pdf

Ngày tải lên : 18/02/2014, 11:20

... unfolded proteins in the ER GmPDIS-1 and GmPDIM associate with proglycinin (glycinin precursor prior to proteolytic processing), and GmPDIL-1 and GmPDIL-2 associate with proglycinin and b-conglycinin ... (B) Microsomes were treated without (lanes and 2) or with (lanes and 4) proteinase K, in the absence (lanes and 3) or presence (lanes and 4) of Triton X-100 Microsomal proteins (10 lg) were analyzed ... reacted exclusively with recombinant GmPDIL-3b (Fig 3A, lanes and 5) Anti-GmPDIL-3a serum reacted with both a 55 kDa and a 59 kDa band in western blot analysis of cotyledon proteins (Fig 3A, lane...

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Tài liệu Báo cáo Y học: Interaction of decorin with CNBr peptides from collagens I and II Evidence for multiple binding sites and essential lysyl residues in collagen pot

Ngày tải lên : 21/02/2014, 15:20

... decorins and decorin cores, respectively Left lane: standard protein markers and their molecular masses (in kDa) The core protein is present as two bands with apparent molecular masses of 47 and 42 ... these bands, whereas keratan sulfate PG are present at a and c bands [23,24] However, not all collagen peptides that contain regions of the collagen molecule falling within the d band interact with ... (white column) and for derivatives with SNHSAc (black) and HCHO/NaBH3CN (gray) are reported The results obtained with samples treated with acetic anhydride (not shown) overlap those with SNHSAc...

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Báo cáo khoa học: Surface-enhanced vibrational spectroscopy for probing transient interactions of proteins with biomimetic interfaces: electric field effects on structure, dynamics and function of cytochromec doc

Ngày tải lên : 22/03/2014, 16:20

... obtained with both electrochemical methods such as cyclic voltammetry, which probe the electron ﬂow between the immobilized cytochrome c and the electrode, and SERR spectroscopy with Soret band excitation, ... demands are imposed on the sensitivity and selectivity of the methodology, which should provide molecular structure and dynamics information In this article, we present the potential of Raman and ... a strong impact on proteins transiently bound at membrane interfaces or to integral membrane proteins Such high electric ﬁelds may perturb acid–base equilibrium, and induce and align molecular...

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Báo cáo khoa học: " Protection of chickens from Newcastle disease with a recombinant baculovirus subunit vaccine expressing the fusion and hemagglutinin- neuraminidase proteins" pdf

Ngày tải lên : 07/08/2014, 20:24

... excised by digestion with Xho I and BamH I, and the HN gene of the La Sota strain was excised by digestion with Not I and BamH I The excised fragments were repaired with T4 polymerase and inserted into ... antibodies and protective efficacy compared with the chickens immunized with the individual glycoproteins In this study, a synergistic effect of the combined inoculation of the F and HN glycoproteins ... or rNDHN(L) Two groups were immunized with a half dose (0.5 × 10 cells) of rNDF(V) and rNDHN(V), and the last group was immunized with the combined rNDF(V) and rNDHN(V)-infected cells The remaining...

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Báo cáo y học: "Serum proteins and paraproteins in women with silicone implants and connective tissue disease: a case–control study" pot

Ngày tải lên : 09/08/2014, 10:21

... women with and those women without paraproteins within the group of women with CTD but no silicone implant (Groups and 5) (data not shown) The paraprotein isotypes were similar in women with and without ... implants); CTD+ and S+, Group (74 women with CTD and with silicone implants); CTD- and S-, Group (14 women with no disease and no silicone implants); CTD- and S+, Group (14 women with no disease ... group without silicone implants In this latter group, one woman with dermatomyositis had two IgG(κ) bands and one IgG(λ) band, and a woman with polymyositis had both IgG(κ) and IgM(λ) bands The...

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Báo cáo y học: "erum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis" doc

Ngày tải lên : 09/08/2014, 13:22

... sRAGE and S100 proteins were associated with RA inflammatory factors and autoantibody production, and with the recruitment of classical vascular risk factors to end-organ damage Consistent with ... 82Ser, and serum levels of CRP and S100A8 (Table 5, P < 0.05) MLR analysis of sRAGE levels confirmed the negative associations with RAGE 82Ser, history of vasculitis, and with serum levels of CRP and ... of sRAGE and S100 proteins with clinical inflammatory factors, complications, and CV risk factors in established RA patients S100 A8, A9 and A12 were all elevated in serum from patients with established...

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Báo cáo y học: " Kaposi''''s sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-κB pathway and functionally cooperates with Tat" pptx

Ngày tải lên : 13/08/2014, 13:20

... subunits, IKK1/IKKα and IKK2/IKKβ, and a regulatory subunit, NEMO/IKKγ [7] The IKK complex leads to the inducible phosphorylation of IκB proteins at two conserved serine residues located within their ... FLICE), caspase 10 and cellular FLICE Inhibitory Protein (cFLIP, also known as MRIT) [17] Proteins with two DEDs have been discovered in other viruses as well, including MC159L and MC160 from the ... the classical and the alternate NF-κB pathways [21-24] Several recent studies suggest that binding of NF-κB to HIV-1 LTR may not be sufficient and interaction with additional viral and cellular...

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Báo cáo y học: " The reticulons: a family of proteins with diverse function" pptx

Ngày tải lên : 14/08/2014, 08:20

... channels at axonal paranodes The human RTN1 and RTN3 66-loops share 71% and 63% identity with the RTN4 loop; mouse RTN1 and RTN3 identity with human RTN4 is 67% and 59% Despite this high degree of identity, ... NP_176592 reticulons and their splice isoforms can be variable, even within the same organism [9-11] This divergence in sequence and expression is consistent with evolution of species- and cell-type-specific ... conditions In silico analysis and measurements by CD and NMR of the human isoforms RTN4A and RTN4B reveal a high degree of disorganization, with only short alpha helices and beta sheets that exist...

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Interaction of scribble with zonula occludens and intermediate filament proteins

Ngày tải lên : 14/09/2015, 08:24

... Interact with Scrib 66 2.1.2 ZO-2 and ZO-3 Co-localize and Interact with Scrib in COS-1 71 2.1.3 The Scrib PDZ Domains Interact Directly with ZO-2 and ZO-3 75 2.1.4 ZO-2 and ZO-3 Co-localize with ... domain is composed of six  strands (A-F) and two  helices (A and B) The ligand binding groove is structurally formed by a connecting loop between A and B, B strand and B helix The connecting ... catenins, afadin and actin-binding proteins vinculin and -actinin The TJ is apical of AJ and consists of CAMs claudins, occludin and JAMs These associate intracellularly with the three ZO proteins which...

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Identification and characterization of proteins that interact with zonula occludens proteins

Ngày tải lên : 16/09/2015, 08:31

... (Balda and Anderson, 1993) A B Fig 5: Proposed protein and lipid models of TJs The protein model (A) involves integral membrane proteins that polymerize within the lipid bilayers and interacts with ... acids) and form a globular fold with the Nand C-termini in close proximity in the folded structure It comprises of six β-strands (βA-βF) and two α-helices (αA and αB), which fold into a six-stranded ... acts as a barrier and fence to prevent paracellular diffusion and intermixing of proteins and lipids between the apical and basolateral plasma membrane domains, respectively AJs and desmosomes are...

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Understanding and using english grammar (with answer key)

Ngày tải lên : 19/08/2013, 13:41

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Control of Cell Proliferation and Growth byMyc Proteins

Ngày tải lên : 25/10/2013, 21:20

... and Myc may repress a common set of target genes (Phan et al 2005) Mechanistically, many questions remain open Myc proteins interact with a number of potential co-activator and co-repressor proteins ... adhesion to the basal lamina and Myc disrupts this adhesion; therefore, keratinocytes respond to Myc with premature differentiation and arrest of proliferation (Gandarillas and Watt 1997) The frequent ... in cell proliferation and their proposed functions Control of Cell Proliferation and Growth by Myc Proteins 333 2003) There is clear evidence that this effect is direct and not mediated by activation...

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Public attitudes, stigma and discrimination against people with mental illness

Ngày tải lên : 01/11/2013, 09:20

... intentions, and found that ex-convicts were seen to be more acceptable than people with mental illness, and the only group less favoured by employers were those with tuberculosis (Brand, Jr and Clairborn, ... distance expressed towards people with schizophrenia, and even higher 181 Public attitudes, stigma and discrimination levels to those with alcohol dependence (Angermeyer and Matschinger, 1997) A revealing ... where we are and where we want to go 184 G Thornicroft and A Kassam The three core problems Stigma theories have not been enough to understand the feelings and experiences of people with mental...

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Tài liệu unit 10 and 11 modal verds with key

Ngày tải lên : 29/11/2013, 13:11

... walked past me without saying a word She me a can't have seen b can't see c can't have been seen d can be seen 39 I think the match Everybody's gone into the stadium and you can hear ... be typed c need to type d needn't typing 34 The museum is open to everybody It between 9am and 5pm a visits b visited c can visit d can be visited 35 The train by bad weather I am not ... completely ripe a can be picked b can pick c needn't pick d should be picking 53 This letter , not handwritten a should be typing b should be typed c needn't type d needn't be typed ...

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Tài liệu Reading and Writing Binary Data with SQL Server doc

Ngày tải lên : 14/12/2013, 18:16

... SqlDataAdapter(selectCommand, ConfigurationSettings.AppSettings["Sql_ConnectString"]); da.UpdateCommand = new SqlCommand(updateCommand, da.SelectCommand.Connection); da.UpdateCommand.CommandType = CommandType.Text; ... new DataSet( ); // Define select and update commands for the DataAdapter String selectCommand = "SELECT Id, Description FROM " + TABLENAME; String updateCommand = "UPDATE " + TABLENAME + " " ... // Create the connection and command SqlConnection conn = new SqlConnection( ConfigurationSettings.AppSettings["Sql_ConnectString"]); SqlCommand cmdWrite = new SqlCommand(sqlWrite, conn); // Create...

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Tài liệu Reading and Writing Binary Data with Oracle pdf

Ngày tải lên : 14/12/2013, 18:16

... Create the connection and command OracleConnection conn = new OracleConnection( ConfigurationSettings.AppSettings["Oracle_ConnectString"]); OracleCommand cmd = new OracleCommand(sqlText, conn); ... da.FillSchema(table, SchemaType.Source); OracleCommandBuilder cb = new OracleCommandBuilder(da); // Create a row containing the new BLOB, CLOB, and NCLOB data DataRow row = table.NewRow( ); row[ID_FIELD] ... based on the national character set of the server with a maximum size of GB This data type maps to a String The Oracle NET data provider handles CLOB and NCLOB data as Unicode Each character is therefore...

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Tài liệu Security Agreement and Pledge For Use with Letter of Credit pptx

Ngày tải lên : 20/12/2013, 17:15

... Tax Board, at any time, and disclose information given Bank to the Applicant All owners / authorized signers must sign and include their titles The Applicant understands and agrees that his application ... Security Agreement and Pledge For Use with Letter of Credit The signer(s) certifies that he/she is authorized to execute this Credit Application on behalf of the Applicant named below, and that all ... AGREEMENT, ALL IF YOU HOLD TITLES IN BOTH A AND B YOU MUST CHECK TITLES AND SIGN FOR BOTH TRUSTEES A President Chairman of the Board Vice President PRINT NAME AND TITLE NEXT TO AUTHORIZED SIGNATURE...

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