clinical trials in the elderly
Báo cáo khoa học: " Hemodynamic goals in randomized clinical trials in patients with sepsis: a systematic review of the literature" pptx
Ngày tải lên :
13/08/2014, 03:21
... hemodynamic goals in clinical trials and whether this variation is associated with patient outcomes To better understand the hemodynamic goals in clinical trials in the sepsis research, and to inform future ... [23] In this trial there was no difference in mortality rates between the study groups The differing results in the these two trials may have been caused by differing sample sizes of the trials, ... in the field of sepsis Key messages • Most sepsis clinical trials reviewed did not include hemodynamic goals of therapy Of note, the four largest clinical trials evaluating novel therapies in...
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Tài liệu Clinical trials in gynecological cancer ppt
Ngày tải lên :
13/02/2014, 07:20
... are being designed In addition to possible benefits for relapsed disease, these trials could provide valuable information for first-line therapy Infrastructure for clinical trials In the remainder ... conducted at the NIH Clinical Center, are routinely summarized in PDQ In addition, cancer trials sponsored by the US Department of Defense, the National Institute of Cancer Clinical Trials Group, the ... regulations Financial support for clinical trials The effective conduct of clinical trials requires a major commitment of time and other resources An ongoing commitment to clinical trials in gynecological...
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Tài liệu Vaccines for preventing influenza in the elderly (Review) docx
Ngày tải lên :
13/02/2014, 18:20
... Trevino SC, Ybarra D The effect of a multivitamin on the immunologic response to the in uenza vaccine in the elderly Infectious Diseases in Clinical Practice Vol 10, Lippincott Williams & Wilkins, ... Efficacy of in uenza vaccine in the elderly: reduction in risks of mortality and morbidity during an in uenza A (H3N2) epidemic for the elderly in nursing homes International Journal of Clinical & ... good coverage in those who most need it or the diluting effect on vaccines for in uenza of other agents circulating in the community (causing ILI, clinically indistinguishable from in uenza), might...
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Tài liệu Cognitive Impairment in the Elderly – Recognition, Diagnosis and Management docx
Ngày tải lên :
13/02/2014, 18:20
... an initial open-ended approach, e.g asking: “What you think the change in your memory and thinking is due to?” b In setting up the visit for disclosure, consider patient privacy and ask whether ... driving and to instruct these patients to stop driving If the physician learns that the patient continues to drive despite this instruction, the physician is required to notify the Superintendent ... Drug Interactions Major drug interactions associated with memantine include drugs which increase the pH in urine (e.g carbonic anhydrase inhibitors) Exercise caution when prescribing memantine...
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Tài liệu Manifestations of Pulmonary Tuberculosis in the Elderly: A Prospective Observational Study from North India pptx
Ngày tải lên :
15/02/2014, 13:20
... the groups DISCUSSION Tuberculosis is becoming increasingly common in the elderly and burden of the disease in them is likely to continue to increase substantially.3,4 Moreover, with increasing ... symptoms in elderly patients with TB This results in a delay in the presentation of the elderly to health care facilities, thereby resulting in a delay in the commencement of ATT The delay in presentation ... hence must be kept in mind during the diagnostic evaluation of elderly patients.11 Several findings of the current study are in accordance with the results of this meta-analysis In the present study,...
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PROSTHETIC REHABILITATION OF MISSING TEETH AND ORAL HEALTH IN THE ELDERLY pptx
Ngày tải lên :
05/03/2014, 18:20
... albicans Rinsing the dentures in the evening and keeping them overnight in the open air can indeed be the easiest way to carry out "disinfection" (Stafford et al., 1986) However, 10 minute soaking in ... been the most fundamental etiological factor for the dramatic increase in caries among the Finnish children in the beginning of the 1950's (Rytömaa et al., 1980) Not surprisingly, increase in the ... habits in the home-living elderly J Oral Rehabil 1997;May;24(5):332-7 V Nevalainen MJ, Närhi TO, Ainamo A Five-year follow-up study on the prosthetic rehabilitation of the elderly in Helsinki, Finland...
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Healthy Lifestyle in the Elderly’s View in Romania and Latvia docx
Ngày tải lên :
05/03/2014, 21:20
... (39%), the rest of them – in households of several individuals In Timisoara the majority of the elderly live in couples, the size of other households is about the same, but the proportion of the single ... Healthy Lifestyle in the Elderly s View in Romania and Latvia Figure Number of individuals in the households of the elderly in Latvia and Romania Figure Size of the homes of the elderly in Jelgava and ... with their community residents, than it is in Latvia Both the elderly in Dumbravita and those in Jelgava feel well in their homes, and they like their apartments or houses In Jelgava 73% of the elderly...
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Preventing Disability in the Elderly With Chronic Disease doc
Ngày tải lên :
05/03/2014, 21:20
... understanding of the dynamics of family caregiving to low-income and frail elderly individuals living in the community It is examining how community and home care services diminish the effect ... Impact in a community setting continues Further evidence of the effectiveness of the CDSMP can be found in a study funded by Kaiser Permanente One year after completing the CDSMP, participants in the ... AHRQ Pub No 01-0009 eating, or using the toilet.8 Many elderly people can maintain or improve their functional ability by attending the CDSMP and practicing its principles CDSMP improved health...
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Tuberculosis in the elderly doc
Ngày tải lên :
06/03/2014, 04:20
... from 6025 cases in 1992 to 3534 cases in 2000 [1] Despite these declines in absolute numbers, the proportion of cases among the elderly has remained stable, with the elderly accounting for 23% of ... malignancies The differences in the presentation of pulmonary TB among the elderly can therefore be explained by the already known physiologic changes that occur with aging, and they must be kept in mind ... age The elimination of routine laboratory monitoring is based on some recent studies demonstrating the efficacy of clinical monitoring For example, a public health TB clinic that used clinical...
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Access to unapproved therapeutic goods Clinical trials in Australia pdf
Ngày tải lên :
07/03/2014, 08:20
... unapproved therapeutic goods - clinical trials in Australia October 2004 Page 10 of 104 Therapeutic Goods Administration Classification of Clinical Trials Clinical Trials of Medicines Clinical trials ... the clinical trial is raised by the TGA within certain agreed timeframes (see below) The scheme mirrors the scheme in place for the regulation of clinical trials of medicines in the UK More information ... unapproved therapeutic goods Clinical trials - an overview Classification of clinical trials Clinical trials of medicines Medical device trials Regulation of medicine and medical device clinical trials...
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Prevention of falls in the elderly living at home pdf
Ngày tải lên :
14/03/2014, 17:20
... important factor in the decline of autonomy Indeed, the fear of falling can result in changes in motor function in the elderly, for example in walking behavior (Maki, 1997) The elderly frequently ... Multiple factors are involved in the risk of falling These factors may be intrinsic to the person and the aging process, behavioral, or found in the person’s immediate environment The main risk factors ... improvement in the health of the elderly, thus extending the period of physical autonomy, and retarding the onset of the effects of aging The fact that the majority of elderly people are currently living...
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HEALTH CARE MAINTENANCE IN THE ELDERLY pdf
Ngày tải lên :
14/03/2014, 20:20
... 1995;92)suppl):1672 12.Byrington RP, Jukema JW, Salonen JT et al Reduction in cardiovascular events during pravastatin threapy: Pooled analysis of clinical events of Pravastatin Atherosclerosis Intervention ... 13.Grundy SM, Cleeman JI, Rifkind BM, Kuller LH Cholesterol lowering in the elderly population: Coordinating committee of the National Cholesterol Education Program Arch Intern Med 1999;159:1670-8 ... physical examination and testing Ann Intern Med 2002 May 136:652-9 4.Goldberg TH, Chavin SI, Preventive Medicine and Screening in Older Adults, JAGS March 1997, vol 45, no 27 Data from Mayo Clinic,...
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Inappropriate Medication Use and Health Outcomes in the Elderly docx
Ngày tải lên :
14/03/2014, 20:20
... toward the null, indicating the strong confounding effect of the total number of prescriptions taken Adding predisposing and enabling variables in Model C, the coefficient remained virtually the ... control for the underlying confounding problem and therefore help minimize the endogeneity The full Model F adds in the prior health-status and health-condition variables The coefficient of inappropriate ... across the different model specifications, suggesting the relative robustness and reliability of the full Model F In specifying the full model, there was a concern about multicollinearity within the...
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Anticoagulation in the Elderly pot
Ngày tải lên :
14/03/2014, 20:20
... on the quality of anticoagulation, frequently assessed by the percentage of INR values in the therapeutic interval and expressed as the “time in the therapeutic range” (TTR) Even in clinical trials, ... associated with the likelihood of not receiving VKAs in the multivariate analysis was increasing age No other single factor, including the presence of contraindications to oral anticoagulation influenced ... is therefore recommended For anticoagulation in the therapeutic range, dabigatran etexilate was compared to warfarin in the RE-LY study including AF patients and in the RE-COVER study including...
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Health Council of the Netherlands Undernutrition in the elderly pdf
Ngày tải lên :
22/03/2014, 13:20
... in the elaboration of the criterion for unintentional weight loss and in the fact that reduced food intake is indeed included in the LPZ as criterion, but not in the LASA study Further, in the ... differences in the numbers of elderly people in the different care settings, the LPZ results that concern data from all participating elderly people are dominated by the findings in nursing and care ... in the elderly The prevalence estimates are presented in Table A3 To gain insight into the effect of the differences in the criteria between the LPZ and LASA on the prevalence data, both definitions...
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Stroke in the Elderly ppt
Ngày tải lên :
22/03/2014, 13:20
... Defining the elderly population 1.5 Summary 1.6 References Acute stroke care 2.1 Intravenous alteplase therapy 2.2 Very elderly in clinical trials 2.3 Outcomes of thrombolytic therapy in the ... success in the elderly (Figure 4) include use of physiotherapy and motor training to improve mobility, constraint-induced movement therapy (14), swallowing therapy for dysphagia, speech therapy ... Learning objectives ●● ●● ●● ●● Gain insight into the prevalence, incidence and economic impact of stroke in the elderly Learn about the role of age in stroke outcomes and burden Be aware of the...
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Sleep disorders in the elderly pot
Ngày tải lên :
22/03/2014, 14:20
... insomnia include sleep onset insomnia (difficulty initiating sleep), sleep maintenance insomnia (difficulty maintaining sleep throughout the night), early morning insomnia (early morning awakenings ... up later in the evening, despite begin sleepy and despite continuing to wake up too early in the morning This can result in restricted sleep and daytime sleepiness similar to that in insomnia ... usually begins with conducting a complete sleep history focusing on EDS, unintentional napping, snoring, and other sleep disorder symptoms If possible, obtaining information from the patient’s...
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Weight loss and malnutrition in the elderly pptx
Ngày tải lên :
22/03/2014, 14:20
... more common for institutionalised elderly than independently living elderly – with more than 50% of people living in hospitals or nursing homes affected.15 Obtaining adequate vitamin D can be a ... malnutrition in the elderly – the shared role of GPs and APDs • noting that a BMI
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Falls in the Elderly potx
Ngày tải lên :
22/03/2014, 14:20
... surfaces, are involved in falls among the elderly Many of these factors can be modified Figure shows how intrinsic and extrinsic factors can combine to change the likelihood of falling in the elderly ... programs can reduce the rate of falls in the elderly In one study,34 the interactive group had a relative risk of falling of 0.39 compared with the control group Interventions included the modification ... multifactorial intervention to reduce the risk of falling among elderly people living in the community N Engl J Med 1994;331:821-7 In watching patients perform the "Up & Go" test or the "Get-Up...
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Compression of morbidity in the elderly pot
Ngày tải lên :
22/03/2014, 14:20
... Similar declines occur in other organ systems What would be the full range of eects if declines in the immune and in ammatory systems were prevented or reversed in the setting of declines in other ... towards intrinsic factors The formally assigned ``cause of death'' becomes increasingly irrelevant compared with the underlying frailty, the inability of the aging organism to withstand even a minor ... one-half the amount of disability in 1587 the last one or two years of life The same results obtained in males and in females, and in those without disability in 1962 and 1986 This 100% decrease in...
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