... rest or during exercise or the exercise-related increase in EDVI and the corresponding LDT values were found in both IDCM subgroups Results Systolic and diastolic time intervals The clinical characteristics ... heterogeneous termination LV isovolumic 338 time intervals were found to be increased at the expense of LV diastolic time inheartfailure patients (17,18) Since our findings and other previous ... lack of increase in LV dyssynchrony during dobutamine stress in patients with wide QRS duration (20) In contrast, Kurita et al reported on an increased mechanical dyssynchrony during pacing–induced...
... LXRα is expressed predominantly in tissues involved in lipid homeostasis in the liver, intestine, adipose tissue, and macrophages LXRα and LXRβ are equally effective in promoting reverse cholesterol ... increased despite the fact that all patients, according to the study design, were receiving inhibitors of the renin–angiotensin system and the majority were receiving beta-blockers and aspirin ... exemption Ad hoc interpreters, including family members, friends, untrained members of the support staff, and strangers found in waiting rooms or on the street, are commonly used inclinical encounters...
... detection of inflammatory and destructive changesin finger and toe joints, tendons, and entheses in patients with PsA by comparison with MRI, x-ray, andclinical findings Materials and methods ... al Ratingen scoring system [11] by an experienced musculoskeletal radiologist (AV) blinded to clinicaland other imaging findings Clinical examination All 25 persons underwent clinical examination ... observed US and MRI were more sensitive to inflammatory and destructive changes than x-ray andclinical examination, and US showed a high interobserver agreement for bone changesand a lower interobserver...
... hepatic injury in some dogs and may be subclinical in more cases The changes occurred both early (within 24 hours) and later at the third and fourth re-examination In most cases the increase ... creatinine values at examination and However, creatinine decreased from examination to examination in 82% of the sampled dogs (p < 0,05 Sign test) Discussion At the first examination within a ... glutamate dehydrogenase (GLDH), creatine kinase (CK) and creatinine were determined using an auto analyzer Konelab 30 (Thermo Clinical Labsystems Oy, Vantaa, Finland) Commercial reagents from Termo...
... grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the other stream The two streams flow together to be one stream and the sampling point St.4 is ... and periphery of the Seto Inland Sea The location of the research area and the distribution of the citrus groves in Matsuyama region are shown in Fig Matsuyama is situated in Shikoku Island in ... under dark condition, and the temperature was maintained constant between 10°C and 30°C RESULTS AND DISCUSSION Materials runoff characteristics and variation in the reservoir Fig indicates time courses...
... important topics and improve both your skills and confidence in problem-solving Since the information is placed in a realistic setting, your recall of key facts and concepts inphysiologyand pharmacology ... medication; • continue to develop your problem-solving skills Using This Book ClinicalPhysiologyand Pharmacology is written primarily for undergraduate students studying modules inphysiologyand pharmacology ... understanding of many types of biological andclinical factors They are intended to help you prepare for problems associated with clinicalphysiologyand pharmacology that you may meet both in formal...
... important topics and improve both your skills and confidence in problem-solving Since the information is placed in a realistic setting, your recall of key facts and concepts inphysiologyand pharmacology ... medication; • continue to develop your problem-solving skills Using This Book ClinicalPhysiologyand Pharmacology is written primarily for undergraduate students studying modules inphysiologyand pharmacology ... understanding of many types of biological andclinical factors They are intended to help you prepare for problems associated with clinicalphysiologyand pharmacology that you may meet both in formal...
... motifs in domains and ( 70% identical residues), particularly in the DNA-binding region 732 (domain 1) which contains an HTH motif [21] and the metal-binding and dimerization domains (domain 2) ... regarding ferritin regulation in Streptomyces species In addition to the 11 proteins listed in Tables and 2, minor changesin other proteins were observed These proteins may be involved in other reactions ... increase P5 Medium increase DNA-binding protein of the ferritin family sco0596 P2 Medium increase Phosphatidylethanolaminebinding protein sco4018 Name P1 Large increase Proteins GenBank accession...
... (2001) Postprandial responses of individual fatty acids in subjects homozygous for threonine or alanine encoding allele in codon 54 of the intestinal fatty acid binding protein gene Am J Clin Nutr ... assuming 1-random, 2-random and 3-random distribution [27] The molecular associations give the exact pairs of fatty acids in individual diacylglycerol and the exact triplets of fatty acids in individual ... sn-1,2- and sn-2,3diacylglycerol species (Table 3) In nontreated rats there was less 16:0–16:1 and 16:1–16:1 in both sn-1,2- and sn-2,3diacylglycerols and less 18:0–18:1 and 18:1–18:2 in the sn-1,2-diacylglycerols...
... either bind directly to TNF-a receptors on the infected cell and induce apoptosis of the target cell or initiate TNF-related apoptosis-inducing ligand (TRAIL) on NK cells thus activating caspase and ... correlated with decreases in perforin and granzyme production [6] andchangesin granzyme gene (GZMA) expression [8] These deficiencies in NK activity may increase viral load in CFS, incidentally a recent ... cytokine and chemokine expression in CFS patients Neutrophil apoptosis in relation to respiratory burst, cytotoxic activity in CD8 T cells, perforin and granzyme production and CD4+T cell cytokine...
... A, Gauldie J: Adenoviral vectors expressing lymphotactin and interleukin or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models Hum Gene Ther ... FL: Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12 Hum ... lymphocytes from peripheral blood, indicating IL-10 can influence cells in the tumor microenvironment and immune response [15] Another prominent inhibitory cytokine, transforming growth factor-beta (TGF-b)...
... methodology and contributed with the design in collaboration with SB FK, AC and EM contributed in preparing the documents and the protocol for implementing the study CP, GCC, SB and EM prepared and completed ... rates by specific preoperative morbidity in this group of CS patients are presented in Table 10, indicating that eclampsia andclinical signs of uterine rupture had the highest rates at around ... (100.0%) Table 3: Institution where the clinical officers did their internship against the Institution of intership District Hospital CHAM Hospital Central Hospital Outside Malawi Not indicated Total...
... September 2000 and July 2001 The two-stage stratified cluster sampling design was planned by Statistics Finland The sampling frame comprised adults aged 30 years and over living in mainland Finland This ... community-dwelling older adults and those living in long-term care settings Conclusion The self-report of seasonal changesin mood and behavior and of poor illumination indoors seem to be relevant indicators ... mental well-being They may therefore stimulate further research aiming at designing optimal working and living environments in terms of lighting conditions Current indoor lighting standards are...
... capacity and permanent wilting point), and clay content Data have been pooled from all the study sites and from all the trees within the sites Horizontal bars indicate standard errors indicating that ... capacity (pF 2.5) and water content at wilting point (pF 4.2), taking into account the percentage of gravels Finally, predawn and midday water potentials were measured in Q ilex trees during the summer ... values (PET) Predawn and midday water potential were measured in current year shoots Vertical bars indicate standard errors transpiration, resulting in a diminution of length and intensity of water...
... Quercus petraea and an increasing length growth of these branches with increasing Response of beech and oak to shading 167 Figure Growth components measured on seedlings of oak and beech exposed ... nets even in the first part of the growing period (table II, figure 3b and 3c) The significant interaction between the variables Z1 and Z2 for RHG and RGDS in the second part of the growing period ... DISCUSSION Shading affected significantly growth and biomass partitioning of oak and beech seedlings Because previous year growth has after effects on initial twig and leaf expansion of oak and beech,...
... one, two and seven days of stimulation in 15 and osteoprotegerin in different cell lines In opposite to RAGE, NFκB and the proinflammatory cytokines TNF-α and IL-6, the mRNA levels of RANKL and osteoprotegerin ... or to βactin/vinculin (monoclonal mouse) The membrane was then washed four times for five minutes in Tris buffer containing 0.1% Tween-20, and incubated with the corresponding HRPlinked secondary ... degradation into the synovium and the activation of FLS through AGE-RAGE interaction may initiate inflammatory responses In RA, activated NFκB in FLS is involved in the regulation of inflammatory cytokines,...
... who have heartfailure worldwide Heartfailure is primarily a disease of the elderly, and the prevalence of chronic heartfailure increases with advancing age Currently, chronic heartfailure ... chronic shortage of donor hearts Currently, the mainstay of heartfailure treatment is pharmacologic and includes angiotensin converting enzyme inhibitors, angiotensin receptor blockers, b-adrenergic ... 30% and 50% of all patients presenting with heartfailure have diastolic heartfailure (left ventricle [LV] ejection fractionR50%) Diastolic heartfailure was initially believed to be a rare and...
... understanding of the anatomy and pathophysiology of heartfailure The failing heart beats at more than 120,000 beats per day, pumping more than 6,000 L of blood against an increased systemic and ... of Fallot and surgically induced complete heart block [2] This procedure was the landmark beginning of cardiac pacing (Fig 1) For the past 50 years cardiac surgery has been in a continuous state ... a tiny minority of patients who have heart failure, other surgical options may soon provide symptomatic relief for the majority The demand for treatment emerges from an increasingly elderly heart...
... unit with borderline cardiac index and a blood pressure of 110/70 mm Hg Over the next hours the blood pressure remains acceptable on inotropic support but the urine output dwindles and the ankles ... transvalvular gradient [4] Intraoperative myocardial injury remains prevalent in the increasingly elderly surgical population because tolerance to ischemia is reduced in aged myocardium [5] Patients ... had coronary bypass and unstable angina to a glycoprotein IIb/IIIa inhibitor or placebo, the 7-day mortality or myocardial infarction rate was 22.3% in almost 700 patients in the control arm [2]...