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clinical and pathologic issues in patients with amyloidosis practical comments regarding diagnosis therapy and solid organ transplantation

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Báo cáo y học: "Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study" doc

Báo cáo khoa học

... determinations and clinical laboratory tests OP-S participated in the clinical study of patients and contributed to drafting the manuscript DP-P contributed to immunological determinations and clinical ... the same sample were stained with annexin V labeled with FITC and propidium iodide and analyzed in a FACSCalibur flow cytometer In addition, annexin V staining was combined with mAbs specific for ... Rituximab therapy induced improvements in different clinical parameters of most SLE patients included in this study Disease activity (MEX-SLEDAI index) significantly diminished in 90% of patients...
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Báo cáo y học: " Resource utilization in patients with schizophrenia who initiated risperidone longacting therapy: results from the Schizophrenia Outcomes Utilization Relapse and Clinical Evaluation (SOURCE)" pdf

Báo cáo khoa học

... RLAT initiation from 250 patients with schizophrenia The mean number of days spent in the hospital per patient increased from 31 in year -3 to 44 in year -2, to 90 in year -1, and to 141 in year ... WM was involved in the interpretation of data, and critical drafting and revising of the manuscript for important intellectual content All authors (CC, CD, CMK, RDD, LM, and WM) read and approved ... days In a retrospective study at four sites in Germany using a mirror-image design [19], hospitalization rates and duration of inpatient treatment were assessed in patients with schizophrenia and...
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Báo cáo y học: " Assessment of effectiveness measures in patients with schizophrenia initiated on risperidone longacting therapy: the SOURCE study results" ppt

Báo cáo khoa học

... one documented RLAT injection recorded in the injection log and were included in the exposure and discontinuation analysis RLAT status could not be determined for the remaining patients Table presents ... is lifelong and requires family, social, and therapeutic interventions, including antipsychotic therapy, to stabilize and support patients In the SOURCE study, initiation and continuation of ... summarized using frequencies and percentages Continuous measures were summarized with mean, standard deviation, minimum, maximum, and median Clinical effectiveness data were analyzed in patients...
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Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"

Y học thưởng thức

... endoscopy in outpatients with iron deficiency anemia The aim of our study was to investigate the incidence of GI pathological findings in symptomatic and asymptomatic patients with IDA and to identify ... the diagnostic yield of endoscopy in patients with IDA and to define predictive factors of gastrointestinal (GI) lesions causing IDA and identify clinical and biochemical variables that predict ... (1.5) Helicobacter, Inflammatory intestinal disease A list of the upper and lower GI pathological conditions associated with IDA is included in Table The patients were interviewed and responded to...
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Báo cáo hóa học:

Báo cáo hóa học: " Vaccination with a plasmid DNA encoding HER-2/ neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial" pptx

Hóa học - Dầu khí

... I clinical study with only six patients completing all three cycles of vaccine and cytokine administration, this precludes any conclusion regarding the clinical efficacy Further complicating interpretations ... survival for patients in a randomized study failing first line trastuzumab therapy was 25.5 months for patients receiving continuous trastuzumab combined with capecitabine [54] In another randomized ... clinical responses and/ or improved time to relapse when administered in the adjuvant setting in women with Her2-expressing breast cancer as a single agent or in combination with chemotherapy [3-7]...
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Báo cáo sinh học:

Báo cáo sinh học: "Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety" ppt

Hóa học - Dầu khí

... rh-HGF administration (day 14) and the observation period (day 28) to evaluate renal involvement, including serum creatinine and histological findings A phase I/II clinical trial for patients with ... decrease in BP during rh-HGF infusion and renal toxicity induced by repeated rh-HGF dosing, including an increase in urinary excretion of albumin, were potential adverse events in a human study In ... and urinary excretion of albumin and protein was measured before (day 1), during (days and 14), and and 14 days after HGF administration Repeated doses of rh-HGF induced an increase in urinary...
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báo cáo hóa học:

báo cáo hóa học: " Evaluation of the reliability and validity of the Medical Outcomes Study sleep scale in patients with painful diabetic peripheral neuropathy during an international clinical trial" pot

Hóa học - Dầu khí

... study examines perceptions of sleep in an international clinical trial aimed at evaluating the efficacy and safety of the pregabalin, a treatment for pain relief in patients with painful DPN ... interpretation of findings and reviewed the manuscript Acknowledgements We would like to thank all patients and clinical investigators who participated in this clinical trial We also thank Christine de la ... 12 years) in Poland to 63 (STD = 10 years) in Australia Patients in Poland, South Africa and the United Kingdom were slightly younger than in Australia, Germany and Hungary Mean sleep interference...
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báo cáo hóa học:

báo cáo hóa học:" Mapping of the EQ-5D index from clinical outcome measures and demographic variables in patients with coronary heart disease" pptx

Hóa học - Dầu khí

... angina, where a model mapping clinical measures on to the EQ-5D index explained 37% of the variability in the EQ-5D index and also performed poorly in individuals with EQ-5D index values of about ... to derive mapping models for the EQ-5D index in cardiac patients with different levels of disease severity by incorporating into these models multiple demographic factors and clinical cardiac ... studies used in our previous study [14] A main dataset was created using data measured at multiple time points on patients participating in randomised clinical trials [5,6,8,16], and cohort study...
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Báo cáo y học: "Predicting hospital admission and discharge with symptom or function scores in patients with schizophrenia: pooled analysis of a clinical trial extension" doc

Báo cáo khoa học

... or a DSM-IV diagnosis of substance abuse within months before screening (not including nicotine and caffeine addiction) Additional inclusion and exclusion criteria are presented in the previous ... results The combined open-label, intent-to-treat sample included 1,077 patients from the 1,665 patients who enrolled in the double-blind randomized portion of the clinical trials The intent to treat ... in the inpatient setting, they may help to identify which patients are ready for discharge As experience is gained using symptom and functioning instruments, their use in remission criteria and...
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Báo cáo khoa học:

Báo cáo khoa học: "Incidence of synchronous appendiceal neoplasm in patients with colorectal cancer and its clinical significance" docx

Báo cáo khoa học

... evaluate the incidence of synchronous appendiceal neoplasm in patients with resectable CRC in a university hospital, and to determine the clinical significance of these findings Methods Pathological ... demonstrate the clinical significance of these findings The study was approved by the Institutional Ethics Committee Results Two hundred and ninety-three patients were included in this study The patients ... Cystadenocarcinoma of the appendix: an incidental imaging finding in a patient with adenocarcinomas of the ascending and the sigmoid colon BMC Gastroenterol 2003, 3:30 Lyda MH, Noffsinger A, Belli...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot

Báo cáo khoa học

... statistically between the clinical parameters (sex, age, smoking and diabetes history, induction chemotherapy, concurrent chemotherapy regimens and PS) of patients with and without SARP Several reports ... radiochemotherapy with vinorelbine plus cisplatin or carboplatin in patients with locally advanced non-small-cell lung cancer (NSCLC) and an increased risk of treatment complications: Preliminary ... cancer in 2005, and we evaluated clinical and dosimetric factors associated with severe acute radiation pneumonitis (SARP) in 94 patients with a diagnosis of locally advanced NSCLC treated with...
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Báo cáo y học: "A new clinical rating scale for work absence and productivity: validation in patients with major depressive disorder" pot

Báo cáo khoa học

... functioning may prove useful as a clinical tool for monitoring progress during treatment and/ or as an outcome measure in clinical trials for MDD This study seeks to validate a new clinical rating ... In addition, further studies are required to investigate the performance of the LEAPS in non -clinical samples of workers and in other clinical populations in specialist and primary care settings ... functioning and productivity in patients with MDD Methods Scale Development The Lam Employment Absence and Productivity Scale (LEAPS) was designed to assess work functioning and impairment in a clinically...
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Báo cáo y học: " Hemodynamic and clinical onset in patients with hereditary pulmonary arterial hypertension and BMPR2 mutations" pot

Báo cáo khoa học

... Since occurrence of BMPR2 mutations obviously influences the clinical phenotype genetic testing may become of increasing clinical relevance Patients with BMPR2 mutation tend to a more severe clinical ... distinct mutation types with clinical presentation Austin et al [17] showed that PAH patients carrying a truncating mutation in the BMPR2 gene developed a more severe disease than patients without ... gene (promoter and coding regions including flanking intronic regions) and the coding regions of the ACVRL1, ENDOGLIN, and the SMAD8 genes did not reveal any defect Especially, no point mutations...
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Báo cáo khoa học:

Báo cáo khoa học: "Clinical review: Influence of vasoactive and other therapies on intestinal and hepatic circulations in patients with septic shock" ppsx

Báo cáo khoa học

... flow with epinephrine and norepinephrine + dobutamine, as compared with norepinephrine alone NA Epinephrine, norepinephrine in random order to achieve MAP 70–80 mmHg [46] 11 11 Epinephrine 0.3 ... the combination of norepinephrine and dobutamine in patients with septic shock on gastric mucosal flow, as assessed using a laser Doppler technique Epinephrine and dobutamine–nor- epinephrine led ... norepinephrine + dobutamine 0.9 ± 0.4 and LD epinephrine ↑ mucosal blood flow NA [45] Epinephrine 0.48 ± 0.33 versus norepinephrine + dobutamine 0.37 ± 0.2 and 13.6 ± HSBF ↓ with epinephrine pHi...
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Báo cáo y học: "Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer" pdf

Báo cáo khoa học

... detect minimal changes in protein levels [15] Three large independent sample sets with adequate clinical and outcome information were used for training and testing Bioinformaticians were closely involved ... protein synthesis machinery including phosphorylated S6 ribosomal protein and 4EBP1, a group with overexpression of stromal markers including collagen VI, CD31 and caveolin1, and a group defined ... anthracycline and taxane-based therapy Further, in three independent sets, the 10-protein signature had a higher predictive value than clinical variables including tumor size, nodal status and grade in...
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Báo cáo y học:

Báo cáo y học: "Routine versus needs-based MRI in patients with prolonged low back pain: a comparison of duration of treatment, number of clinical contacts and referrals to surgery" pdf

Báo cáo khoa học

... 2007), including both baseline and outcome data “Needs-based MRI” group Up until June 2006, patients at the clinic received an MRI purely on the basis of clinical indications as determined during ... obtained from the standard baseline questionnaire which was included in the patient file: sex, age, severity of low back pain (11point Numeric Rating Scale), leg pain (11-point Numeric Rating ... been introduced into our specialised, outpatient public clinic All patients with LBP referred to the clinic, who fulfil certain inclusion criteria, have since June 2006 received an up-front routine...
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Báo cáo y học:

Báo cáo y học: " Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study" ppt

Báo cáo khoa học

... this in a clinical context in which fluid infusion is unavoidable (that is, in patients with septic shock and in patients immediately after cardiac surgery) Instead of selecting patients with ... decreased in none of the fluid challenges resulting in increased SV, and in 44% of those in which SV did not increase (P = 0.0003) EDV increased in 28% of fluid challenges resulting in increased SV and ... pulse-pressure variation in cardiac surgery patients Solid line, all fluid challenges; dotted line, fluid challenges with concomitant increase in central venous pressure; thin solid line, line of identity...
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Báo cáo y học:

Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"

Y học thưởng thức

... vitamins A (retinol), D (cholecalciferol) and E (α-tocopherol) in patients with CAD MATERIALS AND METHODS The study population included 30 patients having angiographically demonstrated CAD and ... vitamins (retinol, tocopherol and cholecalciferol), and trace elements and heavy metals (Zn, Cu, Fe, Cd, Pb and Mn) in patients with CAD and the control group are shown in Table Compared with the ... increase in urine Cu levels in patients suffering from myocardial infarction (MI) (15) Reunanen et al (1996) found increased levels of serum Cu in patients with CAD (14) In contrast, in our study,...
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Báo cáo y học:

Báo cáo y học: "Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction"

Y học thưởng thức

... CABG In the 11 patients with vessel disease a stenosis > 50% was found in the circumflex artery in patients and in the right coronary artery in patients Complete revascularization in the patients ... Int J Med Sci 2011, ability by the deformation indices two-dimensional strain (2DS) and strain rate (SR), might be an alternative approach in clinical routine Tissue Doppler Imaging (TDI) and ... 24-29 In principle, our findings are confirming previously published studies about infarct detection and size, who described significant differences of the radial and circumferential strain and...
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