chronic lymphocytic leukaemia early stage disease

báo cáo hóa học:" Population preference values for treatment outcomes in chronic lymphocytic leukaemia: a cross-sectional utility study" pdf

Ngày tải lên : 20/06/2014, 16:20

... diagnosed chronic myeloid leukaemia J Med Econ 2008, 11(4):571-84 Levy V, Porcher R, Delabarre F, Leporrier M, Cazin B, Chevret S: Evaluating treatment strategies in chronic lymphocytic leukaemia: ... outcomes associated with four leukaemias: AML, ALL, CLL and CML Expert Review of Anticancer Therapy 2003, 3(3):311-329 Kermani IA, Dehdilani M, Dolatkhah R: Chronic lymphocytic leukaemia in the recent ... chronic lymphocytic leukaemia: Results of a longitudinal investigation over yr European Journal of Haematology 2004, 72(6):381-389 Else M, Smith AG, Cocks K, et al.: Patients' experience of chronic...

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Báo cáo y học: "Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer"

Ngày tải lên : 25/10/2012, 11:48

... and methods In the period from January 2003 through December 2009, a total of 20 women with early- stage invasive uterine cancer underwent vaginal RT with lymphadenectomy in Sapporo Medical University ... cervix Table Clinical characteristics of patients Patient 35 P0(0) histology and clinical stage SCC stage Ib1 gestation at delivery 24 weeks + day birth weight and Apgar 588g score 1(1min.)/1(5min.) ... T, Umemura K, Saito T Pregnancy-related complications after vaginal radical trachelectomy for early- stage invasive uterine cervical cancer Int J Clin Oncol 2007; 12:350-355 Nishio H, Fujii T, Kameyama...

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Báo cáo y học: "Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits"

Ngày tải lên : 26/10/2012, 09:39

... connections The present study aimed to detect the expression of Cx40 and Cx43 in the artery at early stage of high fat diet induced atherosclerosis and to investigate the effects of AT1 antagonist ... endothelium and resulted in the formation of atherosclerosis (9) Javid et al also found that in the early stage of atherosclerosis, the number of Cx43 gap junction plaques increased and the diameter ... large gap junction structures exist between the proliferating vascular smooth muscle cells in the early atherosclerosis of rabbits with elevated expression of Cx43 and Cx40 mRNAs and proteins Losartan,...

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Báo cáo khoa học: A novel gene, fad49, plays a crucial role in the immediate early stage of adipocyte differentiation via involvement in mitotic clonal expansion docx

Ngày tải lên : 16/03/2014, 04:20

... results imply that fad49 is crucial in the immediate early stage of adipocyte differentiation As fad49 appears to play an important role in the early stages of adipocyte differentiation, we focused ... events in the middle and late stage of adipocyte differentiation have been studied relatively thoroughly In contrast, the overall mechanisms of events in the early stage of the differentiation ... imply that fad49, encoding a novel scaffolding protein, plays an important role in the immediate early stage of adipocyte differentiation Results Cloning of full-length mouse fad49 cDNA Using the...

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Treatment Choices for Men With Early-Stage Prostate Cancer doc

Ngày tải lên : 28/03/2014, 23:20

... with early- stage prostate cancer can expect to have many healthy years ahead of them The average age for men to learn they have early- stage prostate cancer is 65 years For all treatments: • Nearly ... in prostate cancer cells Hormone therapy can play a role in treating early- stage prostate cancer For men with high-risk early- stage prostate cancer, it may be used along with radiation therapy ... lubricated finger into your rectum Stages of Early Prostate Cancer The clinical stage of your cancer is important in choosing a treatment The clinical stage tells how much the cancer may have grown...

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báo cáo hóa học:" Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer" pdf

Ngày tải lên : 18/06/2014, 15:20

... advanced clinical stages, yet none of them was routinely used for early diagnostics of breast cancer [55-60] The plasma levels of these biomarkers were quantified in a group of early stage breast ... multi-component classifiers (Fig 3), which clearly showed similar serum proteome patterns identified by MALDI-ToF analyses in different sub-groups of the early stage breast cancer group This finding ... behavior, stress, disease and medical treatment) Identifying and understanding changes in the proteome related to disease development and therapy progression is the subject of clinical /disease proteomics...

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báo cáo hóa học:" Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance" docx

Ngày tải lên : 18/06/2014, 15:20

... B-cell chronic lymphocytic leukaemia: evidence for a pathogenic role of NPAT, CUL5, and PPP2R1B Eur J Cancer 2007, 43:1328-1335 Seiler T, Dohner H, Stilgenbauer S: Risk stratification in chronic lymphocytic ... SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia J Clin Oncol 2008, 26:2252-2257 Dighiero G, Hamblin TJ: Chronic lymphocytic leukaemia Lancet 2008, 371:1017-1029 Grever ... with chronic lymphocytic leukaemia Leukemia 2004, 18:756-762 Messmer BT, Albesiano E, Messmer D, Chiorazzi N: The pattern and distribution of immunoglobulin VH gene mutations in chronic lymphocytic...

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Báo cáo hóa học: " Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells" pot

Ngày tải lên : 18/06/2014, 16:20

... Gattei V, Gaidano G: CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia Haematologica 2008, 93:1575-1579 Hamblin TJ, Davis Z, Gardiner ... Kipps TJ: Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working ... survival in chronic lymphocytic leukemia and immunocytoma Leuk Lymphoma 1996, 22:439-447 Rai KR, Sawitsky A, Cronkite EP, Chanana AD, Levy RN, Pasternack BS: Clinical staging of chronic lymphocytic...

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Báo cáo hóa học: " Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer" pot

Ngày tải lên : 18/06/2014, 16:20

... Therapy of Early Breast Cancer 2009 Ann Oncol 2009, 20:1319-1329 Hanash S: Disease proteomics Nature 2003, 422:226-232 Wulfkuhle JD, Liotta LA, Petricoin EF: Proteomic applications for the early detection ... for early- stage cancer: a review of its progress to a clinically relevant tool Mol Diagn 2004, 8:77-85 Posadas EM, Simpkins F, Liotta LA, MacDonald C, Kohn EC: Proteomic analysis for the early ... patterns that were related to therapy of early breast cancer patients Methods Characteristics of patient groups Seventy patients diagnosed with clinical stage I or II breast cancer were included...

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Báo cáo hóa học: "Quantification of newly produced B and T lymphocytes in untreated chronic lymphocytic leukemia patients" ppt

Ngày tải lên : 18/06/2014, 16:20

... series of newly diagnosed patients with chronic lymphocytic leukaemia Br J Haematol 2008, 141:607-614 Dearden C: Disease- specific complications of chronic lymphocytic leukemia Hematology Am Soc ... very early disease stage the decreased number of Treg observed by Beyer et al [20] This discrepancy may be due to the fact that these authors preferentially analyzed patients at later disease stage ... Characterization of CLL patients All patients enrolled in this study were in a very early stage of disease (Rai stage 0, Binet stage A) and had not been previously treated Their demographic and laboratory...

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Báo cáo sinh học: " Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection" ppt

Ngày tải lên : 18/06/2014, 18:20

... of COX inhibitors early, but not late in the infection cycle [15] In conclusion, our results clearly show that COX activity is required for efficient virus replication in vitro early during MHV ... the cells were placed at 37°C This result demonstrates that COX activity plays an important role early in the virus infection cycle, at a postbinding step Thus, COX activity might either be required ... positive-stranded RNA viruses They are known pathogens in the veterinary field, causing severe diseases in several domestic species [21] Recently, their relevance has increased considerably with...

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Báo cáo hóa học: " Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection" pptx

Ngày tải lên : 20/06/2014, 01:20

... of COX inhibitors early, but not late in the infection cycle [15] In conclusion, our results clearly show that COX activity is required for efficient virus replication in vitro early during MHV ... the cells were placed at 37°C This result demonstrates that COX activity plays an important role early in the virus infection cycle, at a postbinding step Thus, COX activity might either be required ... positive-stranded RNA viruses They are known pathogens in the veterinary field, causing severe diseases in several domestic species [21] Recently, their relevance has increased considerably with...

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báo cáo hóa học:" A Rat Model of Early Stage Osteonecrosis Induced by Glucocorticoids" potx

Ngày tải lên : 20/06/2014, 07:20

... apoptosis in early stages of the disease process Although several other investigations have reported ON in rats following the administration of GCs, our rat model has shown early stage disease regardless ... was observed particularly in Wistar Kyoto and Wister Furth strains This was observed in early stages of the disease- before radiographic change was evident Other studies using blood supply interruption ... a genetic predisposition On the other hand, studying the clinical pathology of ON in the early disease stage (before radiographic findings) is extremely difficult in human subjects Thus, animal...

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CHRONIC LYMPHOCYTIC LEUKEMIA ppt

Ngày tải lên : 27/06/2014, 13:20

... in Chronic Lymphocytic Leukaemia 153 John C Allen and Joseph R Slupsky Chapter The Role of Polymorphisms in Co-Signalling Molecules’ Genes in Susceptibility to B-Cell Chronic Lymphocytic Leukaemia ... and progressive disease prognosticator in chronic lymphocytic leukemia Blood 111 (2), 865-873 [26] Caligaris-Cappio, F (2003) Role of the microenvironment in chronic lymphocytic leukaemia Br J ... advanced stages of the disease and among patients displaying unmutated VH genes, whereas the 13q deletion or a normal karyotype are associated with good prognosis, early Selected Topics in Chronic Lymphocytic...

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Báo cáo khoa học: "Intraoperative radiation therapy in the treatment of early-stage breast cancer utilizing xoft axxent electronic brachytherapy" ppt

Ngày tải lên : 09/08/2014, 04:21

... which utilize radioisotope sources The early results of a clinical trial to evaluate the performance and safety of XB in the outpatient treatment of early- stage breast cancer patients were recently ... irradiation in early- stage breast cancer Am J Surg 2007, 194:456-462 Mehta VK, Dooley W, Griem KL, Dickler A, Haile K, Wazer DE, Kurtzman S, Chadha M, Steven RE, Modin SD, Elliott K: Early expe- ... well as, improved quality of life and decreased medical costs for patients with a diagnosis of early- stage breast cancer Conclusion IORT utilizing XB is feasible and can be accomplished in a total...

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Báo cáo khoa học: " Accelerated partial breast irradiation using multicatheter brachytherapy for select early-stage breast cancer: local control and toxicity" potx

Ngày tải lên : 09/08/2014, 09:20

... feasibility and efficacy of APBI and produced evidences supporting the use of APBI for select early- stage breast cancer patients [810] We pioneered APBI in our country, and this is the first report ... safety of APBI using high-dose-rate (HDR) multicatheter interstitial brachytherapy for select early- stage breast cancer patients and the endpoints were the local control rate, treatment toxicity, ... poor cosmesis Discussion Long-term results of the phase II multicenter APBI trials for select early- stage breast cancer were recently reported [8-10,15] In the RTOG phase II trial [9], 66 patients...

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Báo cáo khoa học: "An investigation of intensity-modulated radiation therapy versus conventional two-dimensional and 3D-conformal radiation therapy for early stage larynx cancer" ppt

Ngày tải lên : 09/08/2014, 09:20

... together the conclusion of these two studies is that IMRT can spare normal tissues in early stage laryngeal disease without a decrease in tumor dose, both compared to conventional techniques and ... relationships that are present in the treatment volumes for early- stage glottic laryngeal cancer We also understand that the utility of IMRT in this disease, and any recommendations that can be drawn ... vocal cords, to include any gross disease that can be delineated by the treating radiation oncologist (though it is often difficult to determine the region of gross disease on imaging except in the...

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Báo cáo khoa học: "Clinical Analysis of stereotactic body radiation therapy using extracranial gamma knife for patients with mainly bulky inoperable early stage non-small cell lung carcinoma" pot

Ngày tải lên : 09/08/2014, 09:20

... with mainly bulky early stage NSCLC who had accepted the SBRT in our institution Methods Patient population and characteristics Forty-three patients with mainly bulky early stage NSCLC pathologically ... repeated every weeks) In these 13 patients, patient was staged T1b (≤ cm), patients staged T2a (3~5 cm), patients staged T2b (5~7 cm) and patients staged T3 (> cm) The mean age of the patients was ... overall survival rates in patients with Stage I disease were 100%, 94%, 81%, 58%, respectively, and 82%, 55%, 37%, 24%, respectively, in patients with Stage II disease (Figure 3, p = 0.005) Overall,...

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$Báo cáo khoa học: " Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer" pot$

Báo cáo khoa học: " Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer" pot

Ngày tải lên : 09/08/2014, 10:21

... of being patients with co-morbid diseases Co-morbid conditions have been shown to affect prognosis in early stage NSCLC [8] Unfortunately, the typical early stage NSCLC patients referred for ... hypofractionated radiation therapy alone in early stage NSCLC, dose of 48 Gy in 12 fractions, using 2D and 3DHRT in 33 patients The largest series of early stage NSCLC patients treated with accelerated ... of pulmonary function, serious cardiovascular disease [9], are often imprecisely staged [10], and up to 43% of the patients die from intercurrent diseases [11] In our present cohort of patients...

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Báo cáo y học: "Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection" docx

Ngày tải lên : 09/08/2014, 10:22

... accurate than ELISA [11], and demonstrated a higher value of serum keratan sulfate in patients with early- stage damage of the articular cartilage undetectable by X-ray imaging [12] These results indicate ... Intraarticular injection of hyaluronan has been wildly utilized clinically as pain relief for the early stage of knee osteoarthritis [15,16] Several studies have reported that hyaluronan has beneficial ... serum keratan sulfate increased after exercise in healthy athletes [25] and in patients with early- stage osteoarthritis [12] Furthermore, keratan sulfate was specifically distributed in the cartilage,...

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