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chemistry and antioxidant activity of carotenoids

Báo cáo khoa học

Báo cáo khoa học " Structure elucidation and antioxidant activity of a novel polysaccharide isolated from Tricholoma matsutake " ppt

Báo cáo khoa học

... absorbance in the presence of the sample and H2 O2 , A0 is the absorbance of the control in the absence of the sample and H2 O2 , and A is the absorbance only in the presence of the H2 O2 2.6 Nuclear ... authors thank Dr Pu Su (Department of Chemistry of Medicinal Natural Products and Key Laboratory of Drug Targeting of Education Ministry PRC, West China College of Pharmacy, Sichuan University) ... important for the protection of living systems Fig shows the percentage hydroxyl radical scavenging effects of TMP-A at the dose of 0.5, 1, 2, 3, 4, and 10 mg/mL and IC50 value of TMP-A was about 7.1...
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Báo cáo y học:

Báo cáo y học: "Behavioral and antioxidant activity of a tosylbenz[g]indolamine derivative. A proposed better profile for a potential antipsychotic agent" pptx

Báo cáo khoa học

... doses of 40 and 80 µmol/kg reduces the activity by 39 and 82% respectively (Number of experimental animals: 3–6) ii In apomorphine pretreated rats, TPBIA (80 µmol/kg) reverses the hyperactivity and ... effects of TPBIA with specific focus on neuroleptic effects, 3) to test its antioxidant activity Figure The Ugo-Basile activity cage (type 7401) The Ugo-Basile activity cage (type 7401) Materials and ... (Number of experimental animals: 4) b) modifies the motor behavior of the experimental animals, c) shows antioxidant activity a) The Polar Surface Area (PSA) of a molecule is defined as the area of...
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Báo cáo vật lý:

Báo cáo vật lý: "Evaluation of In Vitro Antioxidant Activity of 5H-dibenz[b,f]azepine and Its Analogues" ppt

Báo cáo khoa học

... percentage inhibition of LDL oxidation for the standards like BHA and AA was also determined and compared with those of the synthesised compounds (Fig 3) The antioxidant activity of BHA and AA was still ... SD (n = 3) Evaluation of In Vitro Antioxidant Activity 90 antioxidant activity of 5H-dibenz[b,f]azepine and its derivatives on human LDL oxidation and lipid peroxidation activity in the liposome ... mass spectroscopy and elemental analysis The IR spectra of compounds (e) and (f) showed the absent of the N–H absorption band at 3400 cm–1 and the presence of the C=O stretching band at 1600 cm–1,...
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Evaluation of the antioxidant activity of scutellaria baicalensis and its constituents in diabetic rats

Evaluation of the antioxidant activity of scutellaria baicalensis and its constituents in diabetic rats

Tổng hợp

... hepatic (A) CAT activity; (B) SOD activity; (C) GPx activity; (D) protein expression of CAT, SOD and GPx; (E) representative Western Blot images of the protein expressions of CAT, SOD and GPx in STZ-diabetic ... Effects of metformin, baicalin and metformin + baicalin on the hepatic (A) SOD activity; (B) CAT activity; (C) GPx activity; (D) quantifications of the protein expressions of CAT, SOD and GPx ... (GPx) and catalase (CAT) are other antioxidant enzymes that catalyze the conversion of hydrogen peroxide to water Decreases in expression, and in some instances the inactivity of each of these antioxidant...
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Tài liệu Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes docx

Tài liệu Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes docx

Sức khỏe giới tính

... Water-solubility, antioxidant activity and cytochrome C binding of four families of exohedral adducts of C60 and C70 Org Biomol Chem 5:3599–3613 Xiao L, Takada H, Maeda K, Haramoto M, Miwa N (2005) Antioxidant ... Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes CARBON MATERIALS: CHEMISTRY AND PHYSICS A comprehensive book series which encompasses the complete coverage of carbon ... with diameters in the range of 0.5–1.5 nm and 2–100 nm and lengths in the range of 20–1,000 nm, and 1–50 μm for SWNTs and MWNTs, respectively 2 Biomedical Applications of Functionalised Carbon...
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Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt

Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt

Báo cáo khoa học

... bonds between NH of Thr5 and CO of Arg2, as well as NH of Arg2 and CO of Thr5 Structure of cyclic hexapeptides – cYT peptide The NMR data of the cYT peptide were indicative of its flexible nature ... intensity of ROE cross-peaks, and were assigned as strong, medium and weak ˚ represent the family Based on ROE violation > 0.2 A and allowed values of /, w in the Ramachandran map, only one family of ... percentage inhibition of peptide-treated cells and expressed as the mean of three independent experiments activity of 40% at 100 lM concentration Both linear and cyclic ER peptides (lER and cER) showed...
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Tài liệu Báo cáo khoa học: Molecular characterization and allergenic activity of Lyc e 2 (b-fructofuranosidase), a glycosylated allergen of tomato pdf

Tài liệu Báo cáo khoa học: Molecular characterization and allergenic activity of Lyc e 2 (b-fructofuranosidase), a glycosylated allergen of tomato pdf

Báo cáo khoa học

... specific 5¢ -and 3¢ primers selected on the basis of the published sequences for tomato b-fructofuranosidase (GenBank accession no D11350 and S70040) Primers for the short isoform of b-fructofuranosidase ... of 50 kDa would suggest that we had purified the truncated isoform Cloning of the cDNA of two isoforms of tomato b-fructofuranosidase and recombinant expression in E coli For protein expression ... reactivity of some sera to a 9- and a 15-kDa band We could show that the 9-kDa band in the tomato extracts reacts with a specific antibody against the LTP from cherry, Pru av and the 15-kDa band...
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Tài liệu Báo cáo khoa học: Physicochemical characterization and biological activity of a glycoglycerolipid from Mycoplasma fermentans ppt

Tài liệu Báo cáo khoa học: Physicochemical characterization and biological activity of a glycoglycerolipid from Mycoplasma fermentans ppt

Báo cáo khoa học

... presence of minute amounts of endotoxins The comparison of LPS and MfGl-II in the LAL assay shows, as expected, activity of LPS in the range of down to 10 pgÆmL)1, whereas MfGl-II has only activity ... respectively [23,30], and the bands at Fig Infrared spectrum in the spectral range 1800–900 cm)1 (A) and – in the range of the negatively charged phosphate band mas (PO2 ) 1300– )1 1190 cm (B) of hydrated ... water-binding capacity of lecithin headgroups [30] Finally, MfGl-II exhibits a main band at 1245 cm)1 and further weak bands at 1220 and 1260 cm)1 Thus, the phosphate groups of this glycolipid are...
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Báo cáo khoa học: Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design pdf

Báo cáo khoa học: Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design pdf

Báo cáo khoa học

... head domain of up to 4.3 A, and of exposed parts of the Rossmann domain of up to 2.7 A, are observed For the rest of the homotetrameric assembly, only smaller backbone displacements of up to ... 42.3 mm)1ặcm)1) One unit of P2Ox activity was dened as the amount of enzyme necessary for oxidation of lmolặmin)1 of ABTS (which equals the consumption of lmolặmin)1 of O2) under assay conditions ... Data processing and evaluation were performed using the origin 7.5 software Crystallization, data collection and renement of the E542K and L537G mutants Crystals of the E542K, L537G and E542K L537W...
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Báo cáo khoa học: Construction and biological activity of a full-length molecular clone of human Torque teno virus (TTV) genotype 6 pptx

Báo cáo khoa học: Construction and biological activity of a full-length molecular clone of human Torque teno virus (TTV) genotype 6 pptx

Báo cáo khoa học

... SalI double-digestions of the input linear construct yielded three restriction fragments of approximately 2100, 740 and 890 bp with the first enzyme pair, and of 2200, 630 and 890 bp with the latter ... when cloned as tandem repeats [29] and CAV requires either tandem-repeat cloning or excision of the viral genome from the plasmid before transfection [30] The rescue and replication of the viral ... Helsinki, Finland), Eiji Morita and Kazuo Sugamura (Tohoku University School of Medicine, Sendai, Japan), and Eiji Miyagawa (Fujirebio Inc., Tokyo, Japan) for cell lines, and Paivi Norja ¨ ´ and Heidi...
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Báo cáo khoa học: Coiled–coil interactions modulate multimerization, mitochondrial binding and kinase activity of myotonic dystrophy protein kinase splice isoforms pptx

Báo cáo khoa học: Coiled–coil interactions modulate multimerization, mitochondrial binding and kinase activity of myotonic dystrophy protein kinase splice isoforms pptx

Báo cáo khoa học

... protein kinase (DMPK) isoforms and truncation mutants Structural domain organization of DMPK splice isoforms A, C, E and F, and N-terminal and C-terminal truncation mutants of DMPK E used in this ... sequence and (b) the DMPK C terminus [15] In vitro study of one of the six major DMPK splice isoforms has revealed that a relationship must exist between kinase activity and the state of multimerization ... the kinase activity of Rho-kinase and MRCKa is also partly dependent on the presence of a coiled-coil domain [14,18,20] and others have shown that multimerization of the human DMPK A isoform is...
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Báo cáo khoa học: nNOS inhibition, antimicrobial and anticancer activity of the amphibian skin peptide, citropin 1.1 and synthetic modifications pot

Báo cáo khoa học: nNOS inhibition, antimicrobial and anticancer activity of the amphibian skin peptide, citropin 1.1 and synthetic modifications pot

Báo cáo khoa học

... anticancer and antibacterial activity of membrane active peptides, suggests that the anticancer activity is also due to penetration and disruption of the membranes of the cancer cells The selectivity of ... that of a well defined a-helical and amphipathic peptide [9] A number of synthetically modified citropin peptides have significantly greater anticancer and antibacterial activity (and also nNOS activity) ... Replacement of the following residues with Ala show (a) little change in activity for Asp4 and Ser11, and (b) significant reduction in the activity for Phe3, Lys7, Lys8 and Leu16; replacement of the...
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Báo cáo khoa học: Enhancement of intracellular concentration and biological activity of PNA after conjugation with a cell-penetrating synthetic model peptide docx

Báo cáo khoa học: Enhancement of intracellular concentration and biological activity of PNA after conjugation with a cell-penetrating synthetic model peptide docx

Báo cáo khoa học

... influence of nociception on the beating rate of CM measured on day of culture without and with pretreatment with either 0.2 lM of I or II on day and after seeding The basal beating rate of the CM ... FACS and CLSM by providing absolute quantitation of internalized PNA CLSM revealed extensive fluorescence in the cytosol and nucleus of CM and CHO cells after exposure to both the naked PNA I and ... involvement of nonendocytic mechanisms (Fig 3) On the other hand, energy-dependent and -independent mechanisms contributed differently to the cellular uptake of the naked PNA and of the conjugate...
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Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot

Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot

Báo cáo khoa học

... analysis of the calculated structures revealed a short distances between NH of Leu7 and the side chain carboxyl group of the Asp6 residue (< 0.28 nm), and NH of Leu7 residue and C¼O of Leu5 (< ... of a potent endozepine antagonist (Eur J Biochem 268) 6049 Fig RP-HPLC monitoring of N- and C-terminal deprotections and on-resin cyclization of the linear precursor of cyclo128 OP Aliquots of ... medicinal chemistry for increasing the receptor affinity and selectivity of peptide ligands [13,14,27] The Ala-scan of OP has revealed that the side chain of each residue is required for the full activity...
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Báo cáo khoa học: Physical properties and surface activity of surfactant-like membranes containing the cationic and hydrophobic peptide KL4 potx

Báo cáo khoa học: Physical properties and surface activity of surfactant-like membranes containing the cationic and hydrophobic peptide KL4 potx

Báo cáo khoa học

... of the structural and functional properties of the native proteins and thus may offer a useful basis for the design of agents for therapeutic intervention [7] Studies of different fragments and ... Therefore, the objectives of this study were to analyze (a) the effect of KL4 on the physical properties of membranes, in the absence and presence of Ca2+, using fluorescence anisotropy of 1,6-diphenyl-1,3,5-hexatriene ... (DSC) and fluorescence confocal microscopy of giant unilamellar vesicles (GUVs), (b) the effect of the lipid composition on KL4 structure, in the absence and presence of Ca2+, using CD and (c)...
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Báo cáo khoa học: Expression, purification and catalytic activity of Lupinus luteus asparagine b-amidohydrolase and its Escherichia coli homolog potx

Báo cáo khoa học: Expression, purification and catalytic activity of Lupinus luteus asparagine b-amidohydrolase and its Escherichia coli homolog potx

Báo cáo khoa học

... wish to thank Prof Michal Dadlez, Jacek Oledzki, and Jacek Sikora (Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw) for their help and discussion of the mass spectrometry ... activity of the LlA and EcAIII proteins With some of the substrates, no enzymatic activity could be detected, indicating lack or possibly very low level of the corresponding activity Enzyme activity ... According to Parry and Clark [37], expression of the ybiK gene responded to the presence of cysteine and to defects in the cysB gene, and the ybiK knockout mutation impaired the use of glutathione...
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Báo cáo khoa học: Residues near the N-terminus of protein B control autocatalytic proteolysis and the activity of soluble methane mono-oxygenase doc

Báo cáo khoa học: Residues near the N-terminus of protein B control autocatalytic proteolysis and the activity of soluble methane mono-oxygenase doc

Báo cáo khoa học

... characterization of the mechanism of cleavage, the roles of specific amino acids near to the N-terminus in catalytic activity, and the significance of the cleavage reaction in vivo MATERIALS AND METHODS ... degradation offers a mechanism by which their activity, and hence the activity of the whole enzyme complex, could be controlled It also offers an explanation for the persistence of the regulatory ... using BamHI and EcoRI The plasmids for expression of the C-terminally 6-Histagged G13Q mutant of protein B and N-terminal truncations thereof were constructed by PCR amplification of the appropriate...
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Báo cáo khoa học: Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4 doc

Báo cáo khoa học: Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4 doc

Báo cáo khoa học

... Fig Fluorescence quenching and blue shift Fluorescence emission spectra of NATA (a and b) and D16W-D24)37 GGN4 (c and d) in water (a and c) and in 10 mM SDS micelles (b and d) were measured with ... activity of the peptide However, a remarkable increase of the hemolytic activity was observed concomitantly Conformational preferences of the GGN4 analogues Figure summarizes the CD results of ... the CD spectra of the GGN4 analogues, including the native GGN4, showed a strong negative band near 200 nm and a weak and broad band around 222 nm, indicating a predominantly random-coil conformation...
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Báo cáo Y học: A critical motif for oligomerization and chaperone activity of bacterial a-heat shock proteins pot

Báo cáo Y học: A critical motif for oligomerization and chaperone activity of bacterial a-heat shock proteins pot

Báo cáo khoa học

... region on chaperone activity of HspH and HspF Thermally induced aggregation of citrate synthase at 43 °C is depicted as a function of time in the presence of various amounts of a-Hsp proteins (A–D), ... chaperone activity of HspH and HspF Chaperone activity of purified a-Hsp proteins was determined by the CS aggregation assay as outlined in the legend of Fig (A–C) C-Terminally truncated variants of ... in detail, the contribution of their subregions to chaperone activity and oligomerization Tight coupling of chaperone activity and complex assembly B japonicum HspH and HspF oligomers contain...
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Báo cáo sinh học:

Báo cáo sinh học: " Relationship between the loss of neutralizing antibody binding and fusion activity of the F protein of human respiratory syncytial virus" doc

Hóa học - Dầu khí

... to better understand the mechanism of action of HRSV neutralizing antibodies and the impact of resistance to these antibodies upon the fusion activity of the F protein A summary of these results ... sitedirected mutagenesis of the HRSV F protein AD and RS participated in the design, oversight of the conduct of the experiments, and interpretation of the results All authors have read and approved the ... between subgroup A and B, as well as with bovine RSV Given this high degree of conservation, it was somewhat surprising that the functional analysis of the fusion activity of the panel of mutations...
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