... of both starch and pullulan as a substrate Structural comparison of the catalytic site between TVAI and other a- amylases Since pullulan with regular repeats of a- (1,6), a- (1,4), and a- (1,4) glycosidic ... Structure of a- amylase with pullulan model ligand A Abe et al Fig Chemical structures of the repeat units of pullulan, P2 and P5 A solid arrow indicates the main hydrolysing site, anda dashed arrow ... Shimura Y, Ibuka A, Sakai H, Matsuzawa H, Sakano Y & Ohta T (1995) Comparison of primary structures and substrate specificities of two pullulan-hydrolyzing a- amylases, TVA I and TVA II, from Thermoactinomyces...
... contributions All authors designed the study Hideaki Takata carried out the analyses and drafted several versions of the manuscript Hiroki Nogawa and Hiroshi Nagata supervised the data analysis Hiroshi Nagata ... Hiroshi Nagata and Hiroshi Tanaka supervised several versions of the manuscript All authors read and approved the final manuscript Page of 19 Sawada A: The nurse shortage problem in Japan Nurs Ethics ... graduate; therefore, the number of graduates taking the national examination every year is approximately equal to the medical student quota that was in place six years earlier Takata et al Human Resources...
... repeated measures For each gait parameter, a separate model was applied The dependent variable was the gait parameter andthe independent variables were the group (patients or controls), the walking ... quantify gait variability and evaluate gait dynamics of each walk [9,27,28] Briefly, to measure the gait rhythm andthe timing of the gait cycle (i.e., the stride timeandthe swing time) , a ... fear of falling that appears to be related to this increased stride variability, and have an increased risk of falls [8,9] Further, the extrapyramidal, limbic systems, andthe frontal lobe apparently...
... radiograph was obtained after a median of year, the second after a median of years andthe third after a median of 14 years after disease onset The total Ratingen score refers to the last radiograph ... modification of the Larsen score It evaluates 38 joints separately (all proximal interphalangeal and metacarpophalangeal joints, four sites in the wrists, interphalangeal joints of the great toes, and ... in the serum and synovial fluid of patients with RA and other inflammatory joint diseases [10–13] Serum MMP3 levels are correlated with markers of inflammation [10] andwiththe radiographic damage...
... years at thetime of analysis The patient expressed elevated titers of anti-52 kDa Ro(SS -A) and anti-52 kDa La(SS-B) antibodies, had marked hypergammaglobulinemia, and was rheumatoid factor (RF) ... plasma and memory B cells accumulate in the parotid gland but cannot clarify the origin of these cells Whatever the primary aberration in the induction of the salivary inflammation, one abnormality ... Vλ1C–Jλ3, and they shared an almost identical CDR3 (11 amino acids) (Fig 2) However, the rearrangements from the blood were unmutated whereas the rearrangements from the parotid gland B cells had 18 and...
... Anorectal melanoma A rare and highly malignant tumor entity of the anal canal Pathologe 2004, 25:171-7 Ishizone S, Koide N, Karasawa F, Akita N, Muranaka F, Uhara H, Miyagawa S: Surgical treatment ... other anal canal tumors there is often a delay in diagnosis that results in advanced stage disease at thetime of presentation Because anorectal melanomas are rare, staging of the disease has ... comparable to dacarbazine in a randomized trial of cutaneous melanoma, a combination of temozolomide, cisplatin, and liposomal doxorubicin in one patient with metastatic anal melanoma was used with...
... the radial head; the second most common is fracture of the proximal third of the ulna, lateral angulation of the fracture and lateral dislocation of the radial head; proximal ulna fracture with ... Monteggia injury with ipsilateral distal radius and ulna fractures [2]; olecranon fracture and distal radial epiphysis [3]; type II Monteggia fracture with fracture separation of the distal radial ... post-dislocation of the radial head; fracture of the proximal radius and ulna with dislocation of the radial head Three Monteggia equivalent fractures have been described: isolated radial head dislocation;...
... after days of therapy with doxycycline As clinical symptoms were actually more intense on the 3rd day of therapy, therapy was changed to ciprofloxacin, anda rapid response was then observed ... probable As is the case with most common rickettsioses, African tick bite fever usually manifests with acute non-specific flulike symptoms which include fever, nausea, myalgias and headache Thetime ... information Many centres also increasingly perform polymerase chain reaction (PCR) tests as a very sensitive and specific tool to detect R conorii and R africae in a variety of clinical samples, particularly...
... in the study JPM participated in the study design and coordination BB supervised the study, and participated in its design and coordination All authors read and approved the final manuscript Acknowledgments ... (see the text) was passaged onto × 106 fresh MT-2 T cells in the presence or absence of 0.3 mM BME and virus spread was measured for 10 days the rate of appearance of syncytia and CA-p24 antigen ... replicated witha delay of approximately days compared to the wt virus Replication of the Q591L mutant was significantly better, witha delay of only one day compared to the wt virus Of note is that...
... acknowledged Authors’ contributions FJ planned the analysis strategy, analyzed the data and drafted the article in collaboration at all stages with JW Both authors read and approved the final manuscript ... BMI, and duration of programme use were included as covariates Age was not included as a covariate as it was not associated with percentage weight loss in univariate analyses First, separate analyses ... and last recorded weight Separate analyses for each engagement variable Covariates as above and all engagement variables included in the model forum use remained non-significant in men All other...
... andthe grid box faces as half levels with Nhl = Nml + levels The model variables are staggered on an Arakawa-C-grid (Arakawa and Lamb, 1981; Arakawa and Lamb, 1977) where all scalar variables ... models as well as chemical reanalysis which aim at the local emission and immission scale Due to these applications the regional enhancement of the available global reanalysis data has become an ... domain with all available observations assimilated in the model Most reanalyses are available for a global domain such as ERA40 (Uppala et al., 2005) and ERA-Interim (Dee et al., 2011) by the...
... parameters and gives the user a message stating the CHAPTER ■ DATEANDTIME MANIPULATION same If thecurrent day and hour values not lie within the given range, a different message is output and ... performance as follows, although it reduces readability Instead of performing adate call to set each timeanddate variable, you could make one date call that outputs space-delimited values, then ... the parameters to variables with more meaningful names, such as DAY_BEGIN and DAY_END instead of and Making this change helps the readability and it is easier to see what is happening DAY_BEGIN=$1...
... that, the value of action is further evaluated If action has a value of "ff", an onEnterFrame event handler is attached to the messages_mc instance This event handler advances the messages_mc timeline ... set up the buttons on the main timeline that the user can employ to navigate this timeline forward and backward Return to the main timeline Withthe Actions panel open, select Frame of the Actions ... andthe functionality for carrying out either the fast-forwarding or rewinding of the messages_mc timeline is accomplished via an onEnterFrame that gets attached to the messages_mc instance With...
... (India, Pakistan and Bangladesh), Africa andthe Caribbean At thetime of the 2001 Census, Indians were the largest minority group, followed by Pakistanis, Black Caribbeans, Black Africans and ... (Landale, Oropesa and Bradatan 2006) and ethnic enclaves (Wilson and Portes 1980) suggests that some of the immigrant advantage may be due to these parents’ greater access to instrumental and ... Pakistan and Bangladesh have lower education and occupational qualifications than whites, on average, those from India, Africa and China have higher average qualifications (Modood 2003) Although...
... disequilibria and debt accumulation in the periphery This imbalance became unsustainable, and this unsustainability was a causal factor in the global financial crisis of 2007– 08 The paper also maintains ... Greece, Italy, Malta, Portugal, Finland, Estonia, Spain, Cyprus, the Netherlands, and Slovenia Among these, Austria, Belgium, France, Germany, andthe Netherlands are referred to as core countries ... combined withthe financial crisis, implied a collapse of output anda fiscal crisis The inability 9 to depreciate the nominal exchange rate, andthe absence of a supra-national fiscal authority...
... to the action of thea Na-ScTx Lqq5 than the cardiac isoform rNaV1.5 [67]) However, when the overall charge of both the toxins andthe channels are considered together, a plausible explanation ... rectangle the slower the exchange Arrows indicate b-strands and zig-zag lines indicate the a- helix (B) Ribbon diagram of Cn12 showing an a- helix at residues 24–32, three strands of antiparallel b-sheet ... obtain the inactivation time constants pClamp (Axon Instruments) and Origin 4.1 (Microcal Inc, Studio City, CA, USA) software were routinely used during data acquisition and analysis Preparation...
... Kanbayashi and Toyoshi Hosokawa Preface Understanding the rapid changes in the evaluation and management of peripheral neuropa‐ thies, as well as the complexity of their mechanism, is a mandatory ... mPFC and amygdale while acute thermal pain and allodynia associated with PHN illicit larger responses in the thalamus and insula [53] Similar activity patterns are observed in thermal and mechan‐ ... attack are often overlooked without a complex and careful examination A case in point is the anti-diabetic drug Avandia for which the market approval has been a center of dispute Avandia’s active...
... Library Cataloguing in Publication Data Data available Library of Congress Cataloging in Publication Data Data available Typeset by Laserwords Private Limited, Chennai, India Printed in Great ... to have a philosophical stance at all It is clear that van Fraassen has synoptic ideas about the virtues of empiricism andthe nature of philosophy, but it is not always clear what van Fraassen’s ... Chakravartty maintains that almost all inquiry is metaphysical to a degree, including van Fraassen’s stance empiricism Chakravartty also argues that van Fraassen does / Introduction not make a...
... maneuver, anda second transition to come back to uniform motion When the target is far enough from the radar, a pure radial approach to the radar leads to the worst case for transversal and heading ... he has been there as an Assistant Professor of automata theory and programming language translation His main research topics are evolutionary computation applications and network optimization ... trajectory with respect to the radar (radial and tangential projection of velocity heading), magnitude of the transversal acceleration, and magnitude of the groundspeed change There are four quality parameters...