... 7:182 Anie KA: Psychological complications in sicklecelldisease Br J Haematol 2005, 129:723-729 Barakat L, Lash LA, Lutz MJ, Nicolaou DC: Psychosocial Adaptation of Children and Adolescents with ... Haematologica 2007, 92:865-871 Van den Tweel X, Hatzmann J, Ensink E, van der Lee JH, Peters M, Fijnvandraat K, et al: Quality of life of female caregivers of children withsicklecell disease: ... social, and behavioral functioning of children withsicklecelldisease and comparison peers Journal of Pediatric Hematology/Oncology 2004, 26:642-648 11 Panepinto JA: Health-related quality of...
... of the study, acquisition of data, analysis and interpretation of data, and revision of the manuscript He has given final approval of this version for publication, LCD participated in the analysis ... Increased understanding of the association of pain with health-related quality of life (HRQOL) is necessary for improved management of pain and other health outcomes among youth withsicklecelldisease ... Ready J, Workman E, Sedway J, Anthony KK: Pain in children and adolescents withsicklecell disease: An analysis of daily pain diaries Child Health Care 2000, 29(4):225-241 Eaton ML, Haye JS, Armstrong...
... validity of the PedsQL™ Family Impact Module in our population of children withsicklecell disease, we collected data on the disease status of the children withsicklecelldiseaseDisease status was ... coefficient lated (Table 5) The correlations were moderate for parents of children withsicklecelldisease and moderate to high for parents of children without sicklecelldisease Factor Analysis Table ... mean summary and subscale scores for the parents of children with and without sicklecelldisease are reported as medians and interquartile ranges (IQR) Comparisons of summary and subscale scores...
... pulmonary infiltrates or arterial hypoxemia The study excluded children with an exacerbation of reactive airways disease If patients withsicklecelldisease are at increased risk of airway inflammation ... American population, there is paucity of research investigating patients with concomitant asthma and sicklecelldisease Table 2: Results in children withsicklecelldiseasewith and without asthma ... hypoxemia, and a new infiltrate on chest x-ray that required hospitalization and a transfusion of packed red blood cells A cerebral vascular accident diagnosis was based on the new onset of an acute...
... the participants as par prevention ofsicklecelldisease and attitude towards their children withsicklecelldisease Table 4: Participants’ knowledge about causes ofsicklecelldisease and attitudes ... their attitude towards children withsicklecelldisease 37 PARENTAL ATTITUDE TO CHILDREN WITHSICKLECELLDISEASE RESULTS Table 1: Personal data of the participants The data were collated and ... children withsicklecelldisease Calculated value of 19.41 was higher that table value of 12.3 hence knowledge of impact ofsicklecelldisease made significant difference in the attitude of parents...
... carried out as part of standard management of these patients to arrive at a diagnosis by the authors The diagnosis of AVN was made using plain x-rays as the institution at the time of study had ... years [25] Poor life expectancy among SCA patients in sub-saharan Africa may be related to factors like the absence of hydroxyurea therapy that may improve survival [26] or low educational attainment, ... seen in all groups and this calls for a detailed assessment of SCA patients by health care professionals in order to avoid cases of missed diagnosis Additional file 1: Additional radiograph figures...
... children with homozygous sicklecell (SS) disease, 178 withsickle cell- haemoglobin C (SC) disease, 33 withsickle cell- beta + thalassaemia (S beta+ thal) and 14 withsickle cellbeta0 thalassaemias ... Table 6) Discussion The primary aim of this study was to examine the prevalence of depression and loneliness in adult patients withSickleCellDisease in Jamaica and compare it to an age-matched ... Psychometric analyses including confirmatory factor analyses have confirmed that this is a reliable and valid measure of loneliness across a variety of populations [28-30] Hays and DiMatteo [12] have...
... addition to being a potential target for oxidative damage, the vascular endothelium may play a primary role in the generation of oxidants Sultana et al [6] demonstrated that coincubation ofsickle ... at baseline In addition, we observed a ninefold increase in the plasma levels of F2 isoprostanes, a stable marker of lipid peroxidation, in the plasma of ACS patients as compared with that of ... C, Manci EA: Causes and outcomes of the acute chest syndrome in sicklecelldisease N Engl J Med 2000, 342:18551865 Dhalla NS, Elmoselhi AB, Hata T, Makino N: Status of myocardial antioxidants...
... complications of breast cancer at the age of twelve Sicklecelldisease (SCD) is found prevalent in black race, Arabians and the Caribbean [1] It is a hereditary and chronic medical condition that encompasses ... working diagnosis made on initial assessment was that of paranoid schizophrenia (F-20) and co-morbid sicklecelldisease (SCD) (D-57) and malaria (B-50) based on World Health Organization (W.H.O) ... social activities and to share his experience and "pains" with other SCD patients and their parents He was referred to a Hematologist and advised on regular hematinics and prophylactic anti-malaria...
... (SC) disease, sicklecell bz thalassaemia (S bz thalassaemia) and sicklecell b0 thalassaemia (S b0 thalassaemia).7 The internationally accepted definition of SCD, two b-globin gene variants at ... after years of age Children with Hb SS and S b0 thalassaemia were consistently smaller and less sexually mature than those with SC disease and S bz thalassaemia Sexual maturation followed the pattern ... children withsicklecell anaemia, while docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), total polyunsaturated fatty acids (PUFA)72 and cholesterol73,74 were decreased With an imbalance...
... nephropathy (SCN) is an important cause of mortality and morbidity in patients with SCD Sicklecell anemia (SCA) and the related hemoglobinopathies are associated witha large spectrum of renal abnormalities ... rheumatoid factor; SCA: sicklecell anemia; SCD: sicklecell disease; SCN: sicklecell nephropathy; VDRL: Venereal Disease Research Laboratory Author details Department of Internal Medicine, Howard ... hemodynamics with elevations in both effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) These parameters decrease with age as well as with administration of prostaglandin...
... (warm touch) General anaesthesia with endotracheal intubation was performed as total intravenous anaesthesia using Propofol and Fentanyl Cisatracurium was used as a muscle relaxant Surgery was ... anaesthesia for these atrisk patients Case presentation We report the case ofa 10-year-old Angolan boy with homozygous sicklecell anaemia An international aid organization sponsored the medical treatment ... Intermediate Care Unit Pain was managed using Paracetamol and Piritramid intravenously as needed After the surgery, the boy complained ofa relapsing upper abdominal pain Laboratory parameters...
... hospital She was advised instead to visit the antenatal day unit twice a week for regular assessments The woman remained stable until she presented again at 31+4 weeks with lower abdominal pain and ... slight vaginal bleeding It was found that her cervix was dilating and that the baby' s presentation was breech An emergency caesarean section was thus performed under spinal anaesthetic She made a good ... erythromycin, aspirin and LMWH At 24+4 weeks gestation, the woman self-referred witha history of unprovoked vaginal bleeding She was given dexamethasone and was transferred to a centre with Level neonatal...
... effects of the severe anemia that may improve with advances in clinical care” (p 500) It is imperative that growth failure and delayed maturation are recognized as treatable effects and not as “symptoms.” ... References Al-Saqladi, A. , Cipolotti, R., Fijnvandraat, K., & Brabin, B J (2008) Growth and nutritional status of children with homozygous sicklecelldisease Annals of Tropical Paediatrics, 28, ... children withsicklecelldisease Journal of Pediatrics, 145, 622-627 Center for Disease Control (2010) SickleCell Disease: Data and Statistics Retrieved from http://www.cdc.gov/ncbddd/sicklecell/data.html...
... frequency ofsicklecell anemia in African Americans with renal cell carcinoma Acta Haematol 1994;92:119-22 Black WD, Hatch FE, Acchiardo S Aminocaproic acid in prolonged hematuria of patients with sicklemia ... Abbreviation βs βs Sicklecell disease- SS SCD-SS βs / βc Sicklecell disease- SC SCD-SC βs / / βo thalassemia βs / β+ thalassemia thalassemia SCD-S βo thal Sicklecell disease- S β+ thalassemia ... care of children and adults withsicklecell disease, describes the current approach to counseling and also to management of many of the medical complications ofsicklecelldisease Each chapter...
... change after the publication ofa clinical study Specifically, investigators have found that a lack of familiarity, lack of agreement witha treatment modality, and lack of outcome expectancy affect ... Jonas for their assistance with literature searching, database management, and project organization, and Brenda Zacharko for her assistance with budget matters and final preparations of the report ... (median age, years; range, – 22 years), and approximately half were male The majority of patients in both studies were African or African American and had sicklecell anemia The β-globin haplotype...
... L SickleCellDisease Pediatr Clin N Am 2002; 49: 1193-1210 Marchant WA, Walker I Anaesthetic Management of the child withsicklecelldisease Paediatric Anesthesia 2003 13: 473-489 Approval: ... physician or paediatrician is arranged Outpatient Management: Outpatient management ofsicklecell patients with fever is an area that is still being evaluated The Child Health Network recommends an ... procedural sedation and analgesia requires anaesthesia consultation History • Nature, duration, location and severity of pain, how pain compares to previous crises, analgesics already used, associated...
... fibrils with an average diameter of nm (Fig 6C) FX1RP Nt-NES aggregates have a curved appearance, with an apparent average diameter of 10 nm (Fig 6D) They also clustered together and were often ... Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients EMBO J 29, 1248–1261 37 Garcia-Arocena D & Hagerman PJ (2010) Advances in understanding ... & Pastore A (2010) Functional interactions as a survival strategy against abnormal aggregation FASEB J 25, 45–54 32 Adrover M, Pauwels K, Prigent S, de Chiara C, Xu Z, Chapuis C, Pastore A &...
... Science and Culture of Japan (13670289 to T K.), grants and contracts from International Health Cooperation Research Ó FEBS 2002 (1 1A- 1) from the Ministry of Health and Welfare of Japan, and ÔResearch ... spectra were estimated using DQFCOSY spectra; 9–10 Hz for 3J3,4 of residue a and 1–2 Hz for J1,2 of residue b The data are summarized in Table Residue a was assigned as a- L-rhamnopyranose (a- L-Rhap) ... is attached at O4 of residue a [26] Residue b was assigned as b-D-mannopyranose (b-D-Manp) The mannopyranosyl Fig 1H (A) and 13C (B) NMR spectra of the OPS-rich fraction configuration was clearly...
... stronger measure of QOL The Flanagan's quality of life scale (QOLS) is a generic scale but has had particular adaptation for use among persons with chronic diseases [30] A comparison of these generic ... structure of the SF-36 in Jamaicans withSickleCellDisease West Indian Medical Journal 2007, 56(6):491-497 Flanagan JC: Measurement of quality of life: current state of the art Arch Phys Med Rehabil ... relationship [41] Results Demographics and clinical characteristics A total of 491 patients participated (Table 1), consisting of 43% males and 57% females The mean age was 31.3 years ± 9.6 years...