cellular molecular and systemic triggers of tumour angiogenesis
Tài liệu Báo cáo khoa học: Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani pdf
Ngày tải lên :
21/02/2014, 00:20
... presence of several concentrations of ATP (A) or AMP (B) and different concentrations of the inhibitor Each point is the mean of three separate trials Inhibition of AK by the specific inhibitor Ap5A and ... investigations of the distinct molecular characteristics of leishmania AK2 in comparison with its mammalian counterparts and its absolute need of the enzyme for growth and survival of the parasite ... describes the cloning and functional characterization of an AK gene from a genomic library of L donovani as well as its expression and molecular characterization Materials and methods Materials...
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Báo cáo khoa học: Molecular and functional characterization of novel CRFR1 isoforms from the skin pptx
Ngày tải lên :
07/03/2014, 15:20
... for detection of an additional CRFR1e1 protein (band 10) with molecular mass of 20 kDa (Fig 2) Proteins with lower molecular mass than expected included band (39 kDa) for CRFR1f, band (34 kDa) ... fully active alpha isoform and other variants, we conducted a series of cotransfection experiments and compared ligand-induced accumulation of cAMP (Fig 3) Although the level of cAMP accumulated ... expected molecular mass included bands 1, 2, 6–8 and 10 Protein with molecular mass 85–90 kDa (band 1) was seen in all isoforms containing transmembrane domains (Fig 2) and therefore it may represent...
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Báo cáo khoa học: Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis docx
Ngày tải lên :
07/03/2014, 21:20
... 2B that VBARP-L and VBARP-S are coded by these specific exons VBARP-L and VBARP-S code for precursor proteins of 627 and 435 amino acids and with calculated peptide masses of 69 and 49 kDa, respectively ... expressed the predicted molecular mass of protein similar to the in vitro 4095 Molecular characterization of ANKHD1 splice variant A B Fig Expression of VBARP isoforms in vitro and in vivo: (A) In ... confirming the possibility of post-translational modifications and ⁄ or splice variants Subcellular distribution of VBARP To determine the subcellular localization of VBARP isoforms, His-tagged VBARP...
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Market structures and systemic risks of exchange-traded funds pptx
Ngày tải lên :
23/03/2014, 12:21
... lefthand panel) The transaction is overcollateralised by almost 20% of the market value of the ETF, and comprises OECD country equities and bonds numbering more than 1,000 A large share of Japanese ... standards and monitoring, December BlackRock (2011): ETF landscape: global handbook Q1 2011 Committee on the Global Financial System (2005): “The role of ratings in structured finance: Issues and ... implementation of short positions in ETFs traded in Europe expensive Graph ETF asset growth in different markets In billions of US dollars ETFs in Europe and share of physical and synthetic structures...
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Báo cáo khoa học: Molecular and genetic characterization of osmosensing and signal transduction in the nematode Caenorhabditis elegans docx
Ngày tải lên :
30/03/2014, 03:20
... for studies of osmosensing and associated signal transduction mechanisms Little is known about the molecular bases of these processes in animals The forward and reverse genetic and molecular tractability ... genes also causes accumulation of damaged proteins and activation of gpdh-1 expression Green arrows and red lines indicate activation and inhibition, respectively Role of cuticle collagens in regulating ... proteins [11] Mutant alleles of three of these genes, osr-1, osm-7 and osm-11, have been characterized and shown to cause constitutive accumulation of glycerol [25,29] osr-1 and osm-7 are expressed...
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Báo cáo Y học: Molecular and biochemical characteristics of a gene encoding an alcohol acyl-transferase involved in the generation of aroma volatile esters during melon ripening pptx
Ngày tải lên :
31/03/2014, 21:21
... Sequence analysis Both CM-AAT1 and CM-AAT2 encode proteins of 461 amino acids with a theoretical molecular mass of 51.5 kDa and 51.8 and a pI of and 8.5, respectively, and 87% identity at the amino ... recombinant protein was capable of producing esters from a wide range of combinations of alcohols and acyl-CoAs with the exception of ethanol, nonanol, and linalol from acetylCoA, and ethanol, cis/trans-3-hexenol, ... trellis in a greenhouse under standard cultural practices for fertilization and pesticide treatments Flower tagging on the day of hand pollination and daily measurements of internal ethylene (WT fruit...
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Báo cáo hóa học: " Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infection" potx
Ngày tải lên :
20/06/2014, 01:20
... 0.5 μl of reverse-transcription product, 0.1 mM of each primer and μl of QuantumRNA™ 18S internal standard (Ambion, Austin, TX) at a primer:competimer ratio of 4:6 for CYP 3A2 and 2C11 and 3:7 ... profile [15,16], and an inactive control, AdlacZ inactivated by exposure to riboflavin and UV light, were included to study the effect of the immune response against virus capsid proteins and ... evidence of recovery in animals treated with WT (31% of control) AdlacZ (37%) and HDAd (29%) (Figure 1D, p ≤ 0.01) CYP3A2 activity was assessed by separation and quantification of the isoform-specific...
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Báo cáo khoa học: "Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients" doc
Ngày tải lên :
09/08/2014, 09:21
... http://www.ro-journal.com/content/6/1/100 Page of 10 Figure Prognostic value of TATI concentrations in tumour tissue and serum ROC curves showing estimations of the prognostic value of t-TATI in surgically obtained tissue (A) and s-TATI ... the tumour microenvironment and tumour cell invasion [13] In the light of these findings, it could be hypothesized that RT in rectal cancer affects TATI concentrations in tissue and/ or serum and, ... tissue and serum and clinicopathological characteristics Figure TATI expression in tumour tissue and normal mucosa before and after radiotherapy Box plots showing TATI expression levels in tumour...
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báo cáo khoa học: "Cellular transfer and AFM imaging of cancer cells using Bioimprint" pdf
Ngày tải lên :
11/08/2014, 00:22
... reflects the profile of the imaging tip rather than of the rupture Further illustrating the range and variation of cell morphologies, and the potential effect the thick layer of polymer has in ... nature and response of cells, yielding insights into drug responses and effects Considerable variability in the sizes of dimple depressions and ruptures, as well as dynamic formation and grouping of ... physical and chemical approach may yield a better understanding into cell functionality and mechanics Artifacts in the form of bubbles caught trapped between the cell and polymer and ripping of the...
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báo cáo khoa học: "Long-term exposure of CdTe quantum dots on PC12 cellular activity and the determination of optimum non-toxic concentrations for biological use" docx
Ngày tải lên :
11/08/2014, 00:22
... quenching of the emission properties of the QDs is common when recorded in the presence of biological media Previously, we have investigated the effect of QD and protein charge on QD spectra and cellular ... 6) Figures and show the evolution of the UV-vis absorption and PL emission (l ex 480 nm) spectra of non-gel and gel QDs respectively in cell culture medium over time The unusual shape of the UV ... examine the structure and morphology of the two differently sized types of QDs (Figure 3) HRTEM images of the different sized QDs show the highly crystalline nature of both the gel and non-gel QDs...
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báo cáo khoa học: " Molecular and functional analyses of COPT/Ctrtype copper transporter-like gene family in rice" pdf
Ngày tải lên :
11/08/2014, 11:22
... expression of rice COPT1 and COPT5 was influenced by Cu; COPT1 and COPT5 were induced by Cu deficiency and suppressed by overdose of Cu in both shoot and root tissues [29] The expression of other ... expression of COPTs (Figure 8a) Mn deficiency induced COPT1 in root and COPT3 and COPT7 in shoot, and slightly suppressed COPT2 and COPT4 in root Zn deficiency induced COPT1, COPT5, and COPT7 and slightly ... Dennis J Thiele of Duke University Medical Center for providing yeast copper-uptake mutant and plasmids and Dr David Eide of University of Wisconsin-Madison and Dr Hongsheng Zhang of Nanjing Agricultural...
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Báo cáo y học: "Extra-cellular release and blood diffusion of BART viral micro-RNAs produced by EBV-infected nasopharyngeal carcinoma cells" pps
Ngày tải lên :
12/08/2014, 01:22
... one step of at 50°C and one step of 10 minutes at 95°C It was followed by 45 cycles including one step of 15 sec at 95°C and one step of 60 sec at 60°C The following sets of primers and probes ... contributions CG and IB made RNA and c-DNA preparations and PCR analyses CG was involved in the design of the study and preparation of the manuscript AG and ASJ participated in exosome purification and study ... important implications for our understanding of stromal proliferation, angiogenesis, immune escape and possibly metastatic processes Elucidation of the cellular targets of BART miRNAs will be important...
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Báo cáo y học: "Molecular and immunological characterization of allergens from the entomopathogenic fungus Beauveria bassiana" ppsx
Ngày tải lên :
13/08/2014, 13:22
... extracts of soluble fractions lanes 1), 3), 5) and 7), and pellet fractions, lanes 2), 4), 6), and 8) Expression of Bb-Eno1, lanes 1) and 2), Bb-f2, lanes 3) and 4), Bb-Ald, lanes 5) and 6), and Bb-Hex, ... The lengths of the cloned cDNA and genomic sequences, the number of introns, along with an analysis of the predicted ORFs, detailing the number of amino acids, molecular mass, and pIs of the deduced ... Achatz G, Oberkofler H, Lechenauer E, Simon B, Unger A, Kandler D, Ebner C, Prillinger H, Kraft D, Breitenbach M: Molecular cloning of major and minor allergens of Alternaria alternata and Cladosporium...
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MOLECULAR AND PHYSIOLOGICAL STUDIES OF SALT TOLERANCE IN THE SALT SECRETOR MANGROVE AVICENNIA OFFICINALIS
Ngày tải lên :
09/09/2015, 08:13
... Sections of A officinalis young and mature leaves 65 Figure 3.2: Adaxial and abaxial surfaces of A officinalis fresh and dried leaves 66 Figure 3.3: Determination of salt gland density in A officinalis ... 3.4: Salt gland structure from A officinalis leaves 69 Figure 3.5: Estimation of ions in xylem sap of A officinalis 71 Figure 3.6: Estimation of ions in leaf secretions of A officinalis ... project aims to understand some of the physiological aspects of the mangrove A officinalis Identification of differentially expressed salt gland genes and characterization of a Dehydrin gene that...
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Molecular and morphological characterization of caudal neural tube defects in embryos of diabetic swiss albino mice
Ngày tải lên :
11/09/2015, 09:04
... caudal neural tube of embryos of diabetic mice 75 3.5 Development of radial glial cell lineages and migration of neurons are disrupted in the caudal neural tube of embryos from diabetic ... disruption of the surrounding tissues and impaired development of dorsal root ganglia (DRG) The percentage of proliferating cells was found to be increased in the dorsal and ventral domains of the ... the sensory and motor output in both peripheral and central nervous systems, defective development of these cell types may impair the circuitry of the nervous system in the offspring of diabetic...
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Cytokines profiles in patients with rheumatoid arthritis genetic polymorphisms, protein and gene expressions of tumour necrosis factor x interleukin 18 and interleukin 18 binding proteins
Ngày tải lên :
14/09/2015, 18:28
... of C alleles at position -607 and/ or higher frequencies of G alleles at position -137 of the IL-18 promoter gene Alternatively, higher presence of A alleles at position -607 and/ or presence of ... the short arm of chromosome It lies in the class III region of the MHC, about 250 kb centromeric of the HLA-B locus and 850 kb telomeric of HLA-DR In view of its biological effects and gene location ... IL-1α, IL-1β and IL-Ra and analyse them as potential markers of disease susceptibility and severity in local of Chinese RA patients 38 2.2 MATERIALS AND METHOD 2.2.1 Subjects recruitment and sample...
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MOLECULAR AND FUNCTIONAL CHARACTERISATION OF THE ROLE OF HYDROGEN SULPHIDE IN SEXUAL MEDICINE
Ngày tải lên :
12/10/2015, 17:33
... H2S may be twofold; being involved in 1) the relaxation of the corporal smooth muscle; and 2) the inhibition of the penile basal tone The nature and site of H2S effects (molecular /cellular/ neurovascular) ... 1992) The existence of NANC in rat anococcygeus and bovine retractor penis muscle was first reported by Gillespie (Gillespie 1972) and by Klinge and Sjostrand (Klinge and Sjostrand, 1974) Similarly, ... the systemic H2S concentration and H2S biosynthesis in the corpus cavernosum (CC) of these rats but also with increased production of NO in both plasma and CC The cross talk between H2S and NO...
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Molecular and morphological phylogenetics of the faviidae (scleractinia) in singapore
Ngày tải lên :
26/11/2015, 12:47
... symbiotic dinoflagellates, and these form the basis of coral reefs along the tropical and subtropical coasts of the Indo-Pacific and Atlantic Azooxanthellate members, on the other hand, tend to ... understanding of speciation and biogeographic events that shape the distribution of reef corals, enabling researchers to make predictions about responses and the evolution of reefs in light of oceanographic ... using the software STATISTICA 6.0 (StatSoft) To assess overlap between the intra- and interspecific variabilities of COI, relative abundances of sequences at each range of intraspecific and closest...
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Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface pdf
Ngày tải lên :
18/02/2014, 11:20
... from tight, adherens and gap junctions enhances transcellular, rather than paracellular, transport when the brain parenchyma Regulation of angiogenesis and barriergenesis and blood exchange factors ... insulin, transferrin and leptin, to cross the BBB [13] Molecular basis of brain angiogenesis and barriergenesis Hypoxia and the hypoxia-inducible factor system As an embryo develops and its structure ... arteriole length and density [49] The role of 4626 As discussed earlier, angiogenesis and barriergenesis of the brain vasculature occur via the complex coordination of various molecules The molecular...
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Tài liệu Báo cáo khoa học: Molecular and cellular specificity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx
Ngày tải lên :
18/02/2014, 11:20
... immunostaining of CHH and VIH may coincide with a weak or null mRNA labelling and vice versa [26] The existence of a sixth type of cell, producing a mixture of l-epimers of CHH and VIH had to ... Characterization of cell types in relation to CHH and VIH isomers To study the distribution of CHHs and VIHs in the X organ cells, immunohistochemical labelling of whole-mounts of X organ–sinus gland complexes ... Hep-DS2 and HepDW4 were added to the standard mixture as standards Figure 2B shows that the elution time of Hep-dW4 is identical to that of the VIH II fragment By MALDI-TOF MS, the mass of this...
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