cell permeability amp sprouting myosin light chain kinase amp aggrecans
Tài liệu Báo cáo Y học: Convulxin induces platelet shape change through myosin light chain kinase and Rho kinase ppt
... Regulation of actin microfilament integrity in living nonmuscle cells by the cAMPdependent protein kinase and the myosin light chain kinase J Cell Biol 106, 1955–1971 Glass, W.F & Kreisberg, J.I (1993) ... (78.6 ± 11.4 mean grey value) (A) substratum in many cell types [9,29] Protein kinase A, once activated, phosphorylates myosin light chain kinase (MLCK), thus inhibiting its activity and causing ... Adelstein, R.S (1981) Regulation of human platelet myosin light chain kinase by the catalytic subunit of cyclic AMP- dependent protein kinase Nature 291, 252– 256 Klages, B., Brandt, U., Simon,...
- 7
- 392
- 0
Báo cáo khoa học: Identification and functional characterization of an aggregation domain in long myosin light chain kinase ppt
... (1998) Myosin light chain kinase: functional domains and structural motifs Acta Physiol Scand 164, 471–482 Kamm KE & Stull JT (2000) Dedicated myosin light chain kinases with diverse cellular ... factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events: characterization of the human long myosin light chain kinase promoter J Biol ... light- chain kinase content is increased in human sensitized airways Am J Respir Crit Care Med 161, 257–263 15 Aromolaran AS, Albert AP & Large WA (2000) Evidence for myosin light chain kinase...
- 12
- 396
- 0
Báo cáo khoa học: Nerve influence on myosin light chain phosphorylation in slow and fast skeletal muscles pdf
... MLC2 (MLC2v), myosin regulatory light chain 2, ventricular ⁄ cardiac muscle isoform MLC2, myosin regulatory light chain 2, skeletal muscle isoform MLC2 (MLC2v), myosin regulatory light chain 2, ventricular ... light chain subunits is the most studied post-translational modification of myosin Phosphorylation of the regulatory myosin light chain (MLC) is catalysed by a calmodulin-dependent kinase (MLC kinase) , ... Journal 272 (2005) 5771–5785 ª 2005 FEBS 5773 Myosin phosphorylation and denervation C Bozzo et al Fig Myosin heavy chain (MHC) and myosin light chain (MLC) expression in soleus (left side of...
- 15
- 288
- 0
Báo cáo khoa học: Specific degradation of H. pylori urease by a catalytic antibody light chain pptx
... Catalytic features of anti-HpU-9 mAb light chain light and ⁄ or heavy chains from mAbs such as i41–7 [13], i41SL1-2 [14], and ECL2B [15] The light chain of ECL2B mAb was capable of cleaving ... acids by the consecutive reaction [11,18] Therefore, the light chain can cleave peptides with low specificity, suggesting that the light chain possesses two functional sites, recognition and catalysis ... of anti-HpU-9 mAb light chain SDS ⁄ PAGE and western blotting as a possible cause of this difference However, we concluded this was unlikely as we could show that the light chain (HpU9-L) was...
- 9
- 388
- 0
Báo cáo khoa học: DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond pptx
... King SM & Mooseker MS (2000) The light chain composition of chicken brain myosinVa: calmodulin, myosin- II essential light chains, and 8-kDa dynein light chain ⁄ PIN Cell Motil Cytoskeleton 47, 269–281 ... dynein light chain with the nuclear-pore complex Nat Cell Biol 9, 788–796 den Hollander P & Kumar R (2006) Dynein light chain contributes to cell cycle progression by increasing cyclin-dependent kinase ... dynein light chains J Biol Chem 282, 17272–17279 Vadlamudi RK, Bagheri-Yarmand R, Yang Z, Balasenthil S, Nguyen D, Sahin AA, den Hollander P & Kumar R (2004) Dynein light chain 1, a p21-activated kinase...
- 17
- 573
- 0
Báo cáo khoa học: Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway pdf
... in SH-SY5Y cells [26] The present study was undertaken to study the mechanisms by which chronic high doses of morphine inhibit cell proliferation and induce cell death in SH-SY5Y cells, which ... inhibited SH-SY5Y cell proliferation and induced cell apoptosis Previous studies reported that morphine inhibited the growth of various human cancer cells, including neuroblastoma cells, with IC50 ... Morphine-induced cell death in a naloxone-irreversible and PTX-irreversible manner in SH-SY5Y cells (A) Cells were treated with various concentrations of morphine (Mor) for 48 h, and cell viability...
- 15
- 244
- 0
Báo cáo khoa học: Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through both extracellular signal-regulated kinase and phosphatidylinositol 3-kinase⁄Akt pathways pot
... classified into three major groups mediated by the following kinases: extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 MAPK [9,10] Another signaling pathway ... chondroprogenitor cells, a BrdU assay was performed as described previously [7] In brief, N1511 cells were seeded at a density of · 104 cells per well in 96-well plates and grown for 24 h The cells were ... Excellence Program from the Ministry of Education, Culture, Sports, Science and Technology of Japan References Western blot analysis Total cellular protein was prepared by lysing cells in CelLytic...
- 7
- 301
- 0
Báo cáo khoa học: The association of heavy and light chain variable domains in antibodies: implications for antigen specificity pot
... with a k light chain The number of known structures of immunoglobulins with a j-type light chain stored in PDB is much higher (930) We removed all single -chain immunoglobulins and light chain dimers, ... of 640 structures with j light chains In order to obtain a balanced dataset for j and k light chains, whilst, at the same time, preserving diversity among the j light chains, we grouped together ... observed a bias in the usage of light chain V germline genes, whereas this was not the case for the heavy chain V genes There is no intersection between the light chain germlines used in cluster...
- 9
- 387
- 0
Báo cáo khoa học: Structural basis for the interaction between dynein light chain 1 and the glutamate channel homolog GRINL1A docx
... King SM & Mooseker MS (2000) The light chain composition of chicken brain myosin- Va: calmodulin, myosin- II essential light chains, and 8-kDa dynein light chain ⁄ PIN Cell Motil Cytoskeleton 47, 269–281 ... novel cellular proteins that bind to the LC8 dynein light chain using a pepscan technique FEBS Lett 503, 135–141 15 Lo KW, Naisbitt S, Fan JS, Sheng M & Zhang M (2001) The 8-kDa dynein light chain ... recognition by the kDa dynein light chain J Mol Biol 306, 97–108 12 Wang W, Lo KW, Kan HM, Fan JS & Zhang M (2003) Structure of the monomeric 8-kDa dynein light chain and mechanism of the domain-swapped...
- 11
- 474
- 0
Báo cáo y học: "Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren’s syndrome" pptx
... productive light chain gene rearrangements amplified by PCR from genomic DNA As a result, a number of differences became apparent between parotid gland B cells and peripheral blood B cells of this ... were further processed for B -cell analysis Preparation of peripheral blood mononuclear cells FACS sorting of individual B cells and the method of PCR amplification of VL chain gene rearrangements ... distinct B -cell subpopulation accumulated in the parotid gland The mutational frequency and the percentage of mutated light chain genes were greater in the productive VL chain rearrangements of B cells...
- 12
- 441
- 0
Báo cáo y học: "Light chain (AL) amyloidosis: update on diagnosis and management" pps
... or light chain amyloidosis (AL) is characterized by a clonal population of plasma cells in the bone marrow that produce monoclonal light chain of kappa or lambda type Amyloidogenic light chains ... Landauh@mskcc.org Abstract: Light chain (AL) amyloidosis is a plasma cell dyscrasia characterized by the pathologic production of fibrillar proteins comprised of monoclonal light chains which deposit ... (Figure 1) The source of the amyloidogenic light chains is a clone of plasma cells, histologically identical to those seen in the more common plasma cell dyscrasia, multiple myeloma Given these...
- 17
- 236
- 0
báo cáo khoa học: " Successful management of refractory pleural effusion due to systemic immunoglobulin light chain amyloidosis by vincristine adriamycin dexamethasone chemotherapy: a case report" ppsx
... M, Nimer S, Comenzo RL: Risk-adapted autologous stem cell transplantation with adjuvant dexamethasone +/- thalidomide for systemic light- chain amyloidosis: results of a phase II trial Br J Haematol ... et al.: Successful management of refractory pleural effusion due to systemic immunoglobulin light chain amyloidosis by vincristine adriamycin dexamethasone chemotherapy: a case report Journal ... DJ, Venning MC, Ackrill P, Scarffe JH: The treatment of nephrotic syndrome caused by primary (light chain) amyloid with vincristine, doxorubicin and dexamethasone Br J Cancer 1998, 78:774-776 Berk...
- 5
- 305
- 0
Báo cáo y học: "Light chain deposition disease presenting as paroxysmal atrial fibrillation: a case report" ppt
... plasma cell proliferative disorders characterized by tissue deposition of light chain fragments, leading to organ impairment Myeloma is diagnosed in about 40% of patients with LCDD [2] In LCDD light ... patients with LCDD [2] In LCDD light chain fragments not form amyloid fibrils; they are defined as non-amyloid immunoglobulin light chains, and are mostly kappa chains They cause renal failure and ... A, Gallo G: Charge differences between in vivo deposits in immunoglobulin light chain amyloidosis and nonamyloid light chain deposition disease Br J Haematol 2007, 136:723-728 Tennents GA, Lovat...
- 4
- 329
- 0
Báo cáo y học: "Resolution of cast nephropathy following free light chain removal by haemodialysis in a patient with multiple myeloma: a case report" ppsx
... Cytotoxicity of myeloma light chains in cultured human kidney proximal tubule cells Am J Kidney Dis 2000, 36:735-744 Li M, Hering-Smith KS, Simon EE, Batuman V: Myeloma light chains induce epithelial-mesenchymal ... serum light chain load, casts continually precipitate However, in the presence of sustained glomerular ultrafiltrate, they pass through and out of the intranephronal compartment Indeed, light chain ... diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains Clin Chem 2002, 48:1437-1444 Cheson BD, De Bellis CC,...
- 5
- 297
- 0
Báo cáo khoa học: " Pichinde virus induces microvascular endothelial cell permeability through the production of nitric oxide" pot
... Dejana E: Endothelial cell- cell junctions: happy together Nat Rev Mol Cell Biol 2004, 5:261-270 Dewi BE, Takasaki T, Kurane I: In vitro assessment of human endothelial cell permeability: effects ... L-NAME on PIC-induced permeability Effect of4 Effect of L-NAME on PIC-induced permeability Prior to PIC infection, L-NAME was added to HMEC-1 cells at a concentration of 10 nM Permeability was quantified ... confluent HMEC-1 cells were treated with an inhibitor and subsequently infected with PIC at an MOI of Cells were incubated for 72 hrs The cells were then lysed using a bifunctional cell lysis/activity...
- 6
- 228
- 0
Báo cáo khoa học: " Targeting lentiviral vector to specific cell types through surface displayed single chain antibody and fusogenic molecule" pps
... strategy by pairing FMs with SCAbs To generate the SCAb for this study, we first PCR-amplified the light chain and heavy chain variable regions of the aCD20 and linked them with a GS linker To allow ... 293T/CD20 cell line, but not to the control 293T cell line In contrast, the lentiviral vector FUW/VSVG was able to bind to both 293T and 293T/ CD20 cell lines In addition, a quantitative virus -cell ... transfected cells Solid line, analysis on transfected 293T/CD20 cells; shaded area, analysis on 293T cells (B) Analysis of co-expression of the FM and antibody on gated GFP-positive cells FM was...
- 12
- 121
- 0
Báo cáo y học: "Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes" pot
... extracellular receptor kinase 1/2; FLAG, polypeptide protein sequence DYKDDDDK; KD, kinase- deficient; P-ERK1/2, phospho-Thr202/Tyr204-extracellular receptor kinase 1/2; T-ERK1/2, total extracellular ... interleukin-1; ILK: integrin-linked kinase; KD: kinase- deficient; MAPK: mitogen-activated protein kinase; MEK1/2: mitogen-activated protein kinase/ extracellular receptor kinase 1/2; MTT: 3-(4,5 dimethylthiazolyl-2)-2,5-diphenyltetrazolium ... Zhang Y, Wu C: Integrin-linked kinase is localized to cell- matrix focal adhesions but not cell- cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the...
- 9
- 259
- 0
Báo cáo y học: "Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema" ppsx
... hybridization of myosin heavy chain mRNA and enzyme histochemistry in rat skeletal muscles Cell Mol Biol 1997, 43:319-327 Sugiura T, Morimoto A, Sakata Y, Watanabe T and Murakami N Myosin heavy chain isoform ... fails to change myosin heavy -chain distribution of diaphragm Respir Physiol 1996, 104:39-43 Larsson L, Biral D, Campione M and Schiaffino S An age-related type IIB to IIX myosin heavy chain switching ... AM Slow myosin in developing rat skeletal muscle J Cell Biol 1987, 104:447-459 Schiaffino S, Gorza L, Sartore S, Saggin L, Ausoni S, Vianello M, Gundersen K and Lomo T Three myosin heavy chain...
- 10
- 302
- 0
Báo cáo y học: "Tyrosine phosphorylation of myosin heavy chain during skeletal muscle differentiation: an integrated bioinformatics approach" doc
... RasMol viewer [18] Three myosin heavy chain structures were identified: 2MYS, Chicken adult skeletal muscle myosin heavy chain; 1BR2, chicken gizzard smooth muscle myosin heavy chain; and 1B7T, Aequipecten ... beta polypeptide) ITK (IL2-inducible T -cell kinase) FGR (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) 719 Lck Kinase Abl Kinase Itk SH2 Src Kinase LCK ABL1 ITK SRC No No No Yes ... RABIT/Q28641 Myos in heavy chain s keletal m us cle juvenile m yh1 PIG/Q9TV61 Myos in heavy chain 2x 983 m yh1 BOVIN/Q9BE40 Myos in heavy chain 2x m yh1 EQUPR/Q8MJV0 Myos in heavy chain 2x 682 622 m...
- 6
- 192
- 0
Characterization of plasma myosin heavy chain in zebrafish as an important factor for ompa mediated anti phagocytic function
... 1988) Being phosphorylated by myosin light chain kinases or Rho kinases, the myosin light chain can regulate the function of myosin by changing the conformation of myosin heads to detach from actin, ... (Alberts et al, 2001) Each myosin protein was composed with one or two MHCs and myosin light chains Myosin II, a subclass of myosin, for example, contains two heavy chains with each about 2000 ... this structure can hold the two heavy chains together Therefore, myosin II has two heads It also contains light chains (2 per head), which bind the heavy chains in the "neck" region between the...
- 110
- 532
- 0
Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25