cell mediated delayed type hypersensitivity

Báo cáo y học: "Phenotypic alterations in type II alveolar epithelial cells in cell mediated lung inflammation" pdf

Ngày tải lên : 12/08/2014, 15:20

... for the transduction as well as the generation of signals involved in cell- cell as well as in cell- matrix interactions Cell- cell interactions may be direct via contact of tight junction proteins, ... specific T cell function and revealed the induction of peripheral T cell tolerance at the site of inflammation In this study we demonstrate altered AEC II cell morphology in mice with CD4+ T cell- mediated ... SPC-HA Transfer 93,63% Figure cytokine staining in CD4+ T cells Intracellular Intracellular cytokine staining in CD4+ T cells CD4+ T cells from the lung or bronchial lymph nodes (BLN) from either...

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Báo cáo Y học: Mistletoe viscotoxins increase natural killer cell-mediated cytotoxicity pptx

Ngày tải lên : 31/03/2014, 15:20

... enhance NK cell- mediated killing (Eur J Biochem 269) 2597 Fig VTA2 acts on NK–target cell conjugates without a change in extracellular acidiﬁcation rate of NK cells and killing of bystander cells ... of the HLA class I cells Val or C1R-B27, a C1R cell line transfected with the HLA-B27 allele protecting against lysis by NKL cells [33] NK cells may also lyse IgG-bound tumor cells [36], so we ... for the increase in NK cell- mediated cytotoxicity Fig Eﬀect of a VTA3 standard on NK -mediated lysis in the absence of direct cytotoxicity Lysis of K562 target cells by NK cells at E/T ratio of...

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Báo cáo hóa học: " Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits" pot

Ngày tải lên : 18/06/2014, 16:20

... syngeneic Ag-specific SV40-immortalized target cells, and either expanded CTLs or fresh peripheral blood mononuclear cells (PBMCs) as effector cells Methods Cells Specific-pathogen-free primary chick ... (5'-GCA-TGA-CTC-AAA-AAA-CTT-AGCAAT-TCT-G-3') The target cells were confluent monolayers of SV40immortalised rabbit autologous skin cells (106 cells/5-cm Petri dish) infected with 10 PFU /cell of the FPE6 or FPE7 recombinants ... post challenge (days) Figure Tumour cell growth and regression Rabbits were injected i.d with a single dose of non-syngeneic VX2T tumour rabbit cells (107 cells in 200 μl of PBS-), containing...

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Báo cáo sinh học: "Correlation between LTR point mutations and proviral load levels among Human T cell Lymphotropic Virus type 1 (HTLV-1) asymptomatic carriers" potx

Ngày tải lên : 18/06/2014, 18:20

... classified into seven subtypes [12]: the cosmopolitan subtype A, the Central African subtype B, the Australo-Melanesian subtype C, and subtypes D, E, F and G The cosmopolitan subtype A is further divided ... FM: Global epidemic of human T -cell lymphotropic virus type- I (HTLV-I) J Emerg Med 2000, 18(1):109–119 11 Matsuoka M: Human T -cell leukemia virus type I and adult T -cell leukemia Oncogene 2003, ... 19 (61) 20 (69) 19 (56) Lymphocyte subpopulations % CD4 cells 42.9 45.2 46.8 % CD8 cells 28.2 27.3 29.1 % CD25 cells 20.3 22.6 29.8 Subtype A (%) Subgroup A (%) 26 (84) 28 (97) 32 (96) Subgroup...

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Đáp ứng miễn dịch qua trung gian tế bào (Cell-mediated Immunity) potx

Ngày tải lên : 27/06/2014, 02:20

... BC kiềm) Quần thể tế bào TH1 tham gia vào trình gọi tế bào T mẫn muộn (TDTH, viết tắt chữ delayed- type hypersensitivity) Mối tương quan qua lại tế bào TCD4+ ĐTB IL-2 Abbas A K and Lichtman A H ... ĐƯMD dịch thể (humoral immunity - HI) sinh tế bào T đặc hiệu gọi ĐƯMD qua trung gian tế bào (cell- mediated immunity - CMI) B Đáp ứng miễn dịch dịch thể T Đáp ứng miễn dịch qua trung gian tế bào...

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Báo cáo y học: "Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen" pot

Ngày tải lên : 09/08/2014, 10:21

... arthritis in B6 mice induced arthritis Sustained T -cell responses to collagen type II in B6 mice with collageninduced arthritis Inguinal lymph node cells were cultured from naïve mice or mice with ... sustained T -cell responses to any obvious defect in regulatory T cells in B6 mice It has been proposed that pepsin (used to purify collagen) plays an important role in breaking T -cell tolerance ... using chicken type II collagen The disease in B6 mice is milder, but more chronic, with more pronounced and more persistent Tcell responses The maintained presence of inflammatory cell infiltrate...

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Báo cáo y học: "Recruitment of dendritic cells and macrophages during T cell-mediated synovial inflammation" doc

Ngày tải lên : 09/08/2014, 10:22

... leukocytes, and a population of CD11b- mononuclear cells T cell- induced inflammation is accompanied by increases in all of these cell types but especially in cells with the phenotypic characteristics ... (CD45+CD163+ cells) in SRT after adoptive transfer of arthritis Cell surface antigen phenotype of CD45+MHC IIhi cells in SRT after adoptive transfer of arthritis, expressed as proportion of cells positive ... undergoing T cell- mediated inflammation An origin of DCs from monocyte-like cells is consistent with the morphological diversity of the MHC IIhi cells from SRT The majority of MHC IIhi cells in SRT...

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Báo cáo y học: "Apoptotic cell-mediated suppression of streptococcal cell wall-induced arthritis is associated with alteration of macrophage function and local regulatory T-cell increase: a potential cell-based therapy" ppsx

Ngày tải lên : 09/08/2014, 14:22

... Apoptotic cell injection prevented streptococcal cell wall-induced arthritis (a) Rats were injected with streptococcal cell wall (SCW) in addition to arthritis apoptotic cells (Apo, × 108 cells) ... arthritic stage, on the other hand, is induced by T -cell- mediated and macrophage -mediated immune responses, characterized by accumulation of mononuclear cells with release of proinflammatory cytokines ... delayed by injection of apoptotic beta cells [12] These beneficial effects have been mainly related to TGFβ and/or Tregs [11-13] Materials and methods Although such an approach of apoptotic cell...

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Báo cáo y học: " Phytol-based novel adjuvants in vaccine formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responses" doc

Ngày tải lên : 11/08/2014, 10:23

... into 6-well tissue culture plates at × 106 cells/well in ml RPMI/10% FBS, and then stimulated in vitro with killed E.G7-Ova cells or 2C3 cells (1.2 × 106 cells/well) for days in the presence of ... adjuvants on different immune parameters such as antigen-specific humoral responses, antibody isotypes, cellmediated anti-tumor immunity, and autoimmune reactivity in BALB/c, C57Bl/6, and autoimmune-prone ... systems [8] For example, CFA, which is used widely in experimental studies, produces excellent humoral and cell- mediated immunity, but is unsuitable for human and veterinary purposes because of toxicity...

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Báo cáo y học: "Correction: Phytol-based novel adjuvants in vaccine formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responses" pot

Ngày tải lên : 11/08/2014, 10:23

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Báo cáo y học: "CpG increases vaccine antigen-specific cell-mediated immunity when administered with hepatitis B vaccine in HIV infection" pdf

Ngày tải lên : 11/08/2014, 10:23

... assay (LPA) To assess cell- mediated immune responses, whole blood was collected from all subjects at baseline and at 4, 8, 12, 24 and 48 Peripheral blood mononuclear clear cells (PBMC) were isolated ... change in the proportion of cells that expressed CD4 or CD8, nor was there a change in the proportion of memory CD4 or CD8 cells (CD4CD45RO, CD8CD45RO), naïve CD4 or CD8 cells (CD4CD45RA62L, CD8CD45RA62L), ... stronger and more sustained antibody response In this manuscript we report the effect of CPG 7909 on cell mediated responses in these subjects Methods Study Design Full details on the design of this...

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Báo cáo y học: " High Human T Cell Leukemia Virus Type-1(HTLV-1) Provirus Load in Patients with HTLV-1 Carriers Complicated with HTLV-1-unrelated disorders" docx

Ngày tải lên : 12/08/2014, 04:20

... results from polyclonal expansion of HTLV-1 infected cells at the sensitive level of SBH In samples from patients with lymphoma -type ATL without ATL cells, a clonal band(s) was demonstrated in of the ... cells mainly contributed to a high level VL However, it is reasonable that a high VL does not consist of only polyclonally expanded infected cells, but included abundant small clones in the cell ... CD4 T -cell /ȝL 0 P Proviral load(%) 2.0 X103 CD4 T -cell /ȝL ad(%) Proviral loa Case 36M (clinical course) Figure Upper panel shows the sequential measurement of VL (%; solid line) and CD4T-cell...

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Báo cáo y học: " Increased production of viral proteins by a 3''''-LTR-deleted infectious clone of human T-cell leukemia virus type 1" ppsx

Ngày tải lên : 12/08/2014, 04:21

... transformation of a T -cell line induced by human T -cell leukemia virus type Tax protein Retrovirology 2006, 3:71 Furukawa Y, Osame M, Kubota R, Tara M, Yoshida M: Human Tcell leukemia virus type- 1 (HTLV-1) ... consistently expressed in adult T -cell leukemia cells Thus, HBZ may have a functional role in cellular transformation and leukemogenesis [16] HBZ was first found to inhibit the Tax -mediated transactivation ... type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T -cell lymphoma Proc Natl Acad Sci USA 1980, 77:7415-7419 Uchiyama T: Human T cell leukemia virus type...

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**Báo cáo y học: "Resolution of cell-mediated airways diseases Carl G Persson*1 and Lena Uller2" pps**

Ngày tải lên : 12/08/2014, 11:22

... 'autacoids' (self remedy) Important roles of certain cells and cell phenotypes in resolution are also entertained with focus on regulatory T cells, macrophages, and neutrophils [1,35] In addition, ... dendritic cells have occurred, it cannot be excluded that exit of mature and immature dendritic cells into the airway lumen in asthma and COPD [79,80] represents a mode of elimination of these cells ... delineate mechanisms involved in the trans-epithelial elimination of inflammatory cells from the airway wall After cell- to -cell contact at the epithelial base paraepithelial crawling of the leukocyte...

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Báo cáo y học: " A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibodydependent cell-mediated cytotoxicity" ppsx

Ngày tải lên : 12/08/2014, 15:22

... target FRb-positive cells, including engineered cells as well as macrophages from rheumatoid patients, and induced antibody-dependent cell- mediated cytotoxicity (ADCC) of these cells Therefore, ... for hours Unattached cells were rinsed off by two washes of warm PBS; cells attached to the wells were used as the effector cells Target cells, CHOK1, CHO-hFRb, or preB L1.2 cells, were trypsinized ... with CHO-hFRb, CHO-K1, or preB L1.2 cells at a ratio of effector cells to target cells of 50:1 The IgG1 m909 or an isotype control IgG was incubated with cells at varying concentrations IgG1...

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Báo cáo y học: " Phosphorylation regulates human T-cell leukemia virus type 1 Rex function" doc

Ngày tải lên : 12/08/2014, 23:22

... and modulates the transcription and activity of numerous cellular genes involved in cell growth, cell cycle control, DNA repair, and cell differentiation [16-20] The pleiotropic effects of Tax ... derived from a different cell type (COS-7 or HTLV1 transformed T -cell lines), which may produce alternative post-translational modification patterns when compared to 293 T cells Although it is not ... W, Chen IS: Integrated human T -cell leukemia virus II genome in CD8 + T cells from a patient with "atypica" hairy cell leukemia: evidence for distinct T and B cell lymphoproliferative disorders...

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Báo cáo y học: "Retraction: Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells" potx

Ngày tải lên : 13/08/2014, 01:20

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Báo cáo y học: "Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef" ppsx

Ngày tải lên : 13/08/2014, 01:20

... impairs cell- to -cell transmission of HIV-1 in several cell lines and primary CD4 + T cells, and transmission of Vpudefective HIV-1 to target CD4+ T cells is less efficient than that of wild -type ... on target cells promotes HIV-1 cell- to -cell transfer, while tetherin expressed on donor cells inhibits viral transmission [50] The discrepancy between these studies may be due to cell- type- dependent ... virus type envelope glycoprotein J Virol 2009, 83:11966-11978 Jolly C, Booth NJ, Neil SJ: Cell- cell spread of human immunodeficiency virus type overcomes tetherin/BST-2 -mediated restriction in T cells...

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Báo cáo y học: "Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo" ppt

Ngày tải lên : 13/08/2014, 05:20

... or indirect cellular effects that facilitate the survival of the T-lymphocyte, the natural target for HTLV infection and cellular transformation Methods Cells 293T cells and 729 B cell lines were ... 729.HTLV2Δp28 stable cell lines PBMCs (2 × 106) were cultured with irradiated donor cells (1 × 106) in 24 well plates as indicated A representative growth curve of HTLV-2 infected cells is shown Cell viability ... numerous cellular genes involved in cell growth and differentiation, cell cycle control, and DNA repair [16-20] Compelling evidence indicates that the pleiotropic effects of Tax on cellular processes...

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