cell cell adhesion and communication the discovery of toposome
Báo cáo y học: " Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis" pot
... the design and coordination of the study MM, HI, and RS participated in the design of the study and the maintenance of the animals KM provided the animals and gave final approval of the version ... first measured the number of Tregs in the spleen by flow cytometry The percentages of CD4+CD25+ T cells among spleen cells and of CD25+ cells among CD4+ T cells were not different Page of 11 (page ... with that when they were actively immunized, these results nevertheless support a regulatory role of RP105 in the development of arthritis induced by TLR ligands On the other hand, these in vivo...
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Báo cáo khoa học: Injection of poly(b-L-malate) into the plasmodium of Physarum polycephalum shortens the cell cycle and increases the growth rate pot
... increases the growth rate and shortens the duration of the cell cycle is the polymer-inherent isosterism of the carboxylates with the array of phosphates in nucleic acids and, consequently, the competition ... changes in the levels of PMLA in cytoplasm and nuclei, we injected 400 lg of the polymer into M3CVII and LU887 plasmodia (weights of 150 mg) and measured the PMLA contents of nuclear and cytoplasmic ... the mechanism(s) underlying the increase in the growth rate and the shortening of the cell cycle might be related to the ability of PMLA to form complexes with nucleic acid binding proteins and...
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Báo cáo sinh học: " Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow" ppt
... majority of BMSCs (97%) showed remarkable DiI-Ac-LDL and OVA-FITC endocytosis, and VCAM-1 expression Of these, 48% expressed von Willebrand antigen, suggesting their endothelial cell phenotype The other ... (A375M) cells constitutively expressed COX-2 (100% of the cell population) and VLA-4 (50% of the cell population) [32] Therefore, A375M cells were similarly pre-incubated with untreated and LPS-treated ... compared to the adhesion of basal medium-treated B16M cells Therefore, soluble factors from untreated and LPS-treated BMSCs induced the adhesive phenotype in certain B16M cells enlarging the cellular...
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Báo cáo khoa học: " Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines" pot
... in the percentage of cells in the G2/M phase of the cell cycle Since Page of 12 the G2/M phase of the cell cycle is one of the most sensitive to radiation [17], this could explain some of the ... dividing the density of the released DNA band by the density of the total DNA in the lane (the released DNA band plus the unreleased DNA remaining in the well) Page of 12 Cell Cycle Analysis The effect ... Chk1 leading to accumulation of cells in G2/M phase of the cell cycle Our data suggest that other parts of the cell cycle are also affected since the percentage of cells in G2/M never increased...
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Modeling and simulation of cell adhesion and detachment
... applied to the cell and the design of the 18 adhesion assay The research on cell adhesion strength has been conducted from two aspects The first is to relate the macroscopic tensions to the cell- substrate ... constant volume The ligands on the substrate are Figure 3.2 Schematic of vesicle adhesion mediated by the diffusion of the receptors and the binding of the receptor-ligand pairs; n is the surface ... mediated by the diffusion of the receptors and the binding of the receptor-ligand pairs 35 Figure 3.3 Variation of receptor density caused by diffusion of the receptors on the cell surface...
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Tài liệu Ghost Wave - The Discovery of Cortes Bank and the Biggest Wave on Earth pptx
... Island They would then cross another thirty-two miles of ocean to the southern flank of San Clemente Island, a naval base and artillery range populated by unexploded ordnance and a dwindling herd of ... had seen from the air and set a course that soon put them within earshot of what seemed the loneliest bell on the face of the planet The tiny man-made island was laden with guano and inhabited ... breakfast into the deep blue sea The buoys stayed anchored, offering the surfers a point of reference and a measure of relief When the next set of four or five waves broke, they showed that the surf...
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biotechnology and communication the meta-technologies of information - sandra braman
... and the convergence of the biological with the mechanical all reflect and stimulate shifts in the understanding of the nature of life Although the cultural practices of breeding and the use of ... reconsideration of human communication processes as a result of what has been learned about cellular and biochemical communications, and legal and cultural implications of the merging of the digital and ... computing and communication technologies together is just one in a series of types of convergence of communication with other materials and social processes There have been four: The convergence of...
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báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf
... absence of complement; (1) In the presence of Alemtuzumab and heat inactivated sera, the majority of VLC are viable Annexin V (-) and PI (-) cells In contrast, in the presence of Alemtuzumab and ... overall survival of treated animals (Figure 6D) These results confirm the anti-tumor activity of anti-VLC therapy, as observed by others, and further support the use of anti-CD52 therapy in humans ... angiogenesis based on the elimination of VLC, Alemtuzumab may also inhibit angiogenesis via the elimination of B cells and mast cells from the tumor microenvironment; both of these cell types have...
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o cáo hóa học:" Summit on cell therapy for cancer: The importance of the interaction of multiple disciplines to advance clinical therapy" ppt
... disciplines, the testing of new ideas in the research laboratory and in animal models, the development of new cellular therapies and GMP methods to produce these therapies, and the testing of new adoptive ... the field of adoptive cellular therapy of cancer The growing clinical applications and success of adoptive cellular therapy of cancer has been due to the rapid evolution of immunology, gene therapy ... across these diverse disciplines, the testing of new ideas in the research laboratory and in animal models, the development of new cellular therapies and GMP methods to produce these therapies, and...
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Báo cáo hóa học: "Biocompatible micro-sized cell culture chamber for the detection of nanoparticle-induced IL8 promoter activity on a small cell population" pot
... washing the cells with PBS and adding the nanoparticle-containing medium After the exposure time, the cells were analyzed microscopically The total number of cells and the number of fluorescent cells ... in their fabrication, and wrote the main parts of the manuscript GO carried out the transfection of the reporter cell line and was involved in the preparation of the manuscript AS fabricated the ... between the individual cell responses Analysis of the biocompatibility of the MCC Figure The miniaturized cell culture chamber (a) Work flow of the fabrication (b) Design of the MCC The MCC contains...
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SỰ TRUYỀN TÍN HIỆU VÀ GIAO LƯU THÔNG TIN TẾ BÀO (CELL SIGNALING AND COMMUNICATION) pps
... trị ligand amino acid đặc trưng protein thụ thể Sự gắn ligand làm cho thụ thể biến dạng Ligand không tiếp tục tham gia vào đường Các receptor gắn ligand theo quy luật tác động khối (law of mass ... đa tế bào với ligand đặc biệt nói chung xảy nồng độ ligand hầu hết receptor chưa bị choán chỗ Các ligand Ligand (phối tử) phân tử tín hiệu gắn vào thụ thể Các receptor gắn ligand với tính đặc ... nghịch Nồng độ ligand làm phân nửa receptor bị choán chỗ gắn kết với ligand, Kd, xác định thực nghiệm biểu thị lực ligand với receptor Các tác nhân ức chế gắn vào chỗ gắn ligand phân tử receptor...
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Báo cáo sinh học: "Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements." doc
... the scientific community Users of ConSite can either provide an existing alignment of two orthologous sequences or input just the sequences alone and the program will generate the alignment The ... alignment of orthologous sequences; then, automated computer programs were developed to assist the process In this issue of Journal of Biology, Lenhard, Sandelin and colleagues describe their most ... positions in the two aligned sequences, are selected and reported in the output The remainder of the sites, which are not conserved between the two species, are considered to be false positives and are...
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Báo cáo y học: "The role played by cell-substrate interactions in the pathogenesis of osteoclast-mediated peri-implant osteolysis" potx
... These cells fail to express the CD68 antigen and are not believed to be of hematopoietic origin The association of the fibroblastic cells with the bone surface and the ex vivo demonstration that they ... the enzymes that are expressed in these cells and contribute to the resorption of the extracellular matrix component of bone [5-7] Although the expressions of these genes have served as useful ... prosthesis Of importance, in our studies we observed that the levels of expression of both cathepsin K and TRAP were much higher in the cells associated with the bone surface compared with the...
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Báo cáo y học: "The discovery of potential acetylcholinesterase inhibitors: A combination of pharmacophore modeling, virtual screening, and molecular docking studies" pptx
... activities The residual cost (Table 1) is the difference between the cost of null hypothesis and the total cost The larger the difference between the cost of the null hypothesis and total cost, the ... %Y, the percentage of known actives in the hit list (recall); Ht, the number of hits retrieved; D, the number of compounds in the Page of 13 database; E, the enrichment of the concentration of ... decamethonium [10] and donepezil [19] extend to the mouth of the gorge, the opening of the hydrophobic pocket Page of 13 The drug discovery process is both time-consuming and expensive [20] yet...
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Báo cáo y học: "Roles of planar cell polarity pathways in the development of neutral tube defects" ppsx
... established within the plane of the epithelium and promotes the rearrangement of the cytoskeletal components of the cell [97] Although the asymmetric localization of some of the PCP factors has ... arrangement of these PCP core components, appearing to be highly sensitive to the orientation of the cell s sides with respect to the global axis of the epithelium, allows the polarity of the cell to ... mutated embryos, the polarity of the ommatidia of the compound eye and the hairs of the wing and thorax are disrupted, such that rather than pointing in the same direction, they point in multiple...
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báo cáo khoa học: "Hepatocyte growth factor incorporated chitosan nanoparticles augment the differentiation of stem cell into hepatocytes for the recovery of liver cirrhosis in mice" pptx
... kinetics, distribution and stability of HGFCNP in the blood circulation Whether HGF released from the CNP causes the stem cell differentiation or apoptosis of myofibroflasts or both of these functions ... Suppression of inflammatory cytokines could reduce the activation of hepatic stellate cells Inhibition of the proliferation of T cells thereby modulating the pro-inflammatory cytokines such as TNF-a and ... in the knockout model [37] or the fibrolysis of ECM content [38] For better understanding we have compared the contribution of either HSC or MSC in the process of reversal of cirrhosis in the...
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Báo cáo khoa học: " Three-dimensional Huh7 cell culture system for the study of Hepatitis C virus infection" ppsx
... while cultured in the RVW Expression and Organization of Cellular Tight Junction and Polarity Markers in 3-D Huh7 Aggregates While the effect of HCV on cell polarity and TJs (and viceversa) cannot ... expression and organization of the HCV receptors (CD81 and SR-B1), cell adhesion molecules (E-Cadherin and β-Catenin), cellular TJ proteins (CLDN1, ZO-1 and Occuldin-1) and the polarity marker (CD26) ... 4B shows that the majority of Huh7 cells were positive for the HCV E2 glycoprotein and that the entire aggregate was permissive for HCV infection rather than just the cells at the periphery,...
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Báo cáo khoa học: "Three-dimensional Huh7 cell culture system for the study of Hepatitis C virus infection" pdf
... while cultured in the RVW Expression and Organization of Cellular Tight Junction and Polarity Markers in 3-D Huh7 Aggregates While the effect of HCV on cell polarity and TJs (and viceversa) cannot ... expression and organization of the HCV receptors (CD81 and SR-B1), cell adhesion molecules (E-Cadherin and β-Catenin), cellular TJ proteins (CLDN1, ZO-1 and Occuldin-1) and the polarity marker (CD26) ... 4B shows that the majority of Huh7 cells were positive for the HCV E2 glycoprotein and that the entire aggregate was permissive for HCV infection rather than just the cells at the periphery,...
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Báo cáo y học: "The discovery of the first human retrovirus: HTLV-1 and HTLV-2" doc
... primary blood cells, but not with the systems of Sachs and Metcalf These methylcellulose colonies of leukocytes provided too few cells and growth of these cells were limited in number and in time ... Instead, they used the technique previously applied to virus transformed cells of cell growth on a methylcellulose solid surface in the form of cell colonies However, growth was transient and the ... 2) Discoveries of HTLV-1 and HTLV-2 The first detection and isolation of HTLV-1 was in 1979, and the first detection came from the analysis of a T cell line established by J Minna and A Gazdar...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng 9 tr 25