cdk2 cyclina activity in hiv 1 infected and uninfected cells
báo cáo hóa học:" Effectiveness and Safety of Generic Fixed-Dose Combination of Tenofovir/Emtricitabine/Efavirenz in HIV-1-Infected Patients in Western India" doc
... al.: The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through years in antiretroviral-naive HIV- 1- infected patients HIV Clin Trials 2007, 8 :16 4 -17 2 Abstract Gallant ... 39 (18 74) Male (%) 37 (75.5) 71 (77 .1) Female (%) 11 (24.5) 20 (22.9) Sex WHO stage before initiating current or past ART Stage I 15 (30.6) 36 (39 .1) Stage II (10 .2) 10 (10 .9) Stage III (10 .2) ... (49) 37 (40 .1) Duration of HIV infection since diagnosis months, median (range), y 18 .5 ( 316 1) 38 ( 218 5) Pretherapy body mass index, median (range) 21. 365 (14 .3633.2) 23.04 (12 .335 .16 ) Current...
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báo cáo hóa học:" Metabolic and anthropometric parameters contribute to ART-mediated CD4+ T cell recovery in HIV-1-infected individuals: an observational study" potx
... circumference -1. 128 1. 2 81 0.3 817 -0.0033 Waist/hip ratio Fasting glucose -458.084 -28 .17 1 18 3.0 71 23.307 0. 014 8 0.2 310 0.0 718 0.0067 BMI CD95+ CD8+ T cells -0.962 3 .13 6 2.828 0. 919 0.7348 0.0 011 -0. 013 2 ... competing interests 10 11 12 13 14 15 16 Received: December 2 010 Accepted: 29 July 2 011 Published: 29 July 2 011 References Azzoni L, Chehimi J, Zhou L, Foulkes AS, June R, Maino VC, Landay A, Rinaldo ... treatment and disease severity Clin Chem Lab Med 48 :11 47 -11 52 42 Grunfeld C: Dyslipidemia and its Treatment in HIV Infection Top HIV Med 18 :11 2 -11 8 43 Rose H, Hoy J, Woolley I, Tchoua U, Bukrinsky...
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báo cáo hóa học:" HIV-1-infected and HIV-1-uninfected adults in Burkina Faso: a cross-sectional study" pptx
... present in rural than in urban settings, influences T cell activation and maturation in healthy and in HIV- 1- infected individuals in Burkina Faso in west Africa Methods The proportion of circulating ... progression and survival in HIV- 1- infected Africans in London AIDS 19 98, 12 :12 03 -12 09 Low N, Paine K, Clark R, Mahalingam M, Pozniak AL: AIDS survival and progression in black Africans living in south ... present in rural settings, influences T cell activation and maturation in healthy and in HIV- 1- infected individuals Methods Both the National Ethics Committee in Burkina Faso and the Institutional...
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Báo cáo y học: " Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya" doc
... AIDS Research and Therapy 2009, 6 :12 Introduction Recent data show an HIV prevalence in Kenya of 7.4%, resulting in 1. 4 million Kenyans living with HIV [1] An estimated 19 0,000 HIV- infected Kenyans ... 48 weeks in HIV- 1- infected adults in Africa AIDS 2006, 20 :13 91- 1399 Wainberg MA, Miller MD, Quan Y, Salomon H, Mulato AS, Lamy PD, et al.: In vitro selection and characterization of HIV- 1 with ... [http://www.biomedcentral.com/content/supplementary /17 426405-6 -12 -S2.xls] 16 WHO: WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV related disease in adults and children...
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Báo cáo y học: "The incidence of multidrug and full class resistance in HIV-1 infected patients is decreasing over time (2001–2006) in Portugal" potx
... 21 626 3.4 2 .1 5 .1 13 490 2.7 1. 4 4.5 n N incidence 95%-CI n N incidence 95%-CI n N incidence 95%-CI 78 576 13 .5 10 .9 16 .6 203 570 35.6 31. 7 39.7 60 574 10 .5 8 .1 13 .2 63 572 11 ,0 8.6 13 .8 ... 2008, 5 :12 [27,28] for the following drugs: zidovudine, didanosine, lamivudine, stavudine, abacavir, emtricitabine, tenofovir, nevirapine, delavirdine, efavirenz, saquinavir, indinavir, nelfinavir, ... http://www.retrovirology.com/content/5 /1/ 12 450 400 350 300 250 200 15 0 10 0 50 Jan '00 n July '00 Jan ' 01 July ' 01 Jan '02 July '02 Jan '03 July '03 Jan '04 July '04 Jan '05 July '05 Jan '06 11 8 12 9 10 8 224 382 2 81 335 262...
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Guidelines for the use of antiretroviral agents in HIV 1 infected adults and adolescents
... (3.7–6.0) 17 (14 –20) 24 (20–28) 29 (25–34) 13 (11 16 ) 19 (15 –23) 23 (19 –28) 12 (9.7 14 ) 18 (15 – 21) 22 (18 –27) 9 .1 (7.3 11 ) 14 (11 17 ) 17 (14 – 21) 5 .1 (3.9–6.5) 8.6 (6.8 11 ) 12 (9.2 15 ) 3.8 (3.0–5.0) ... (7.6 12 ) 3.8 (2.8–5.0) 6.7 (5 .1 8.7) 9.3 (7 .1 12 ) 2.9 (2.2–3.8) 5 .1 (3.9–6.6) 7 .1 (5.4–9.2) 13 (11 15 ) 18 (15 – 21) 22 (19 –26) 9.8 (8 .1 12 ) 14 (12 17 ) 17 (14 – 21) 8.7 (7.2 10 ) 13 (11 16 ) 17 (14 –20) ... (4.2–6.5) 17 (13 – 21) 25 (20– 31) 33 (26–38) 13 (10 16 ) 20 (15 –25) 25 (20– 31) 11 (9 .1 14 ) 18 (15 –23) 24 (20–30) 8.8 (6.9 11 ) 14 (11 18 ) 19 (15 –24) 4.9 (3.7–6.4) 9.0 (7.0 11 ) 13 (9.9 16 ) 3.7 (2.8–4.9)...
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Báo cáo y học: "i: Randomized controlled trial of Hepatitis B virus vaccine in HIV-1-infected patients comparing two different doses" ppt
... AIDS, explained by an increased expression of HIVinfected cells and faster decrease in CD4 lymphocytes [ 912 ] When compared to general population, the response rate to HBV vaccine in HIV- infected ... ( 51. 3%) 19 (48.8%) 21 (52.5%) 19 (47.5%) 0. 914 Viral load (copies/mL) 75 ,18 7 ± 15 3,305 67,335 ± 11 2,742 0. 811 Viral load (copies/mL) – No (%) ≤ 400 400 – ≤ 20,000 ≥ 20,000 (20%) 11 (36.6%) 13 ... J Infect Dis 19 91, 16 3 :11 38 -11 40 Koblin B, Taylor P, Rubinstein P, Stevens C: Effect of duration of hepatitis B virus infection on the association between human immunodeficiency virus type -1 and...
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Báo cáo y học: " Compartmentalization of the gut viral reservoir in HIV-1 infected patients" ppt
... (AZT) therapy J Gen Virol 19 96, 77 :10 71- 10 81 Brown AJ, Cleland A: Independent evolution of the env and pol genes of HIV- 1 during zidovudine therapy Aids 19 96, 10 :10 67 -10 73 Frost SD, Gunthard HF, ... transcriptase from HIV- 1 Science 19 88, 242 :11 71- 117 3 Wodarz D, Nowak MA: The effect of different immune responses on the evolution of virulent CXCR4-tropic HIV Proc Biol Sci 19 98, 265 (14 11) : 214 9- 215 8 Wolfs ... filling in the incomplete fragment ends with Klenow, phosphorylation using T4 polynucleotide kinase, and insertion into the EcoRV site of pSL 118 0 All enzymes were obtained from Invitrogen (Burlington,...
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Báo cáo y học: "HIV DNA and Dementia in Treatment-Naïve HIV-1-Infected Individuals in Bangkok, Thailand"
... HAD 1. 34X10-2 1. 25X10-2 1. 06X10-4 9.91X107 6 .18 X105 6.28X104 >1 HAD 2.09X10-2 2 .16 X10-2 1. 59X10-4 1. 23X108 3 .15 X106 9.38X103 >1 HAD 2.00X10-2 1. 24X10-2 5.30X10-4 1. 08X108 1. 79X106 5.72X104 >1 HAD ... 3.35X10-2 5.75X10-2 2 .16 X10-4 2.41X108 4.85X107 7.78X104 >1 Non-HAD 1. 89X10-4 9 .10 X10-6 1. 56X10-4 1. 25X106 7.46X102 1. 03X106
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Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States pdf
... receiving PrEP with the Antiretroviral Pregnancy Registry Monitoring of HIV- Uninfected Pregnant Women with Partners Known to Be HIV Infected Clinicians may increasingly be seeing HIV- uninfected ... effective in avoiding seroconversion in uninfected women and offspring in several studies.20, 21 The National Perinatal HIV Hotline (1- 888-448-8765) is a resource for a list of institutions offering ... guidelines focus on HIV- infected pregnant women and their infants Other guidelines outline the use of ARV agents in non-pregnant HIV- infected adults and adolescents, HIV- infected children, and people...
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Báo cáo y học: ": Prevalence of reverse transcriptase and protease mutations associated with antiretroviral drug resistance among drug-naïve HIV-1 infected pregnant women in Kagera and Kilimanjaro regions, Tanzania" pptx
... TMS008 TMS 318 TMS323 10 BF0 61 10 BF0 71 10 BF 110 TMS 013 TMS036 TMS 113 TMS204 B FR.HXB2R B US.JRFL TMS005 TMS004 TMS024 TMS 116 TMS 117 TMS 311 TMS 015 TMS 112 TMS207 TMS148 TMS347 TMS346 TMS 118 TMS 012 TMS348 ... TMS 218 TMS320 TMS1 41 TMS108 TMS3 01 TMS006 TMS 115 TMS127 TMS103 TMS 018 TMS0 01 TMS 314 TMS1 31 TMS 319 D C A Phylogenetic analysis of HIV- 1 pol sequences from HIV- 1 infected pregnant women in Moshi, Kilimanjaro ... EU2 517 34 – EU2 517 46; EU2 517 48 – EU2 517 54; EU2 517 56 – EU2 517 66; EU2 517 68 – EU2 518 21; EU2 518 23 – EU2 518 46; EU2 518 48 – EU2 518 74; and EU2 518 76 – EU2 518 81] http://www.aidsrestherapy.com/content/5 /1/ 13...
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Báo cáo y học: " Detection of HIV-1 RNA/DNA and CD4 mRNA in feces and urine from chronic HIV-1 infected subjects with and without anti-retroviral therapy" pptx
... during HIV- 1 infection, HIV- 1 free virus and infected/ uninfected CD4+ T cells constantly shed from GALT into the intestinal lumen and are discharged with feces Therefore, the amount of HIV- 1 and ... reported in urine by ELISA and Western blot [15 ,16 ] and HIV- 1 DNA has been detected in urine pellets from HIV- 1 infected individuals [17 ,18 ] However, it is not clear whether urine from chronically infected ... for HIV- 1 DNA/ RNA and CD4 mRNA detection in feces and urine samples from HIV- 1 infected individuals In addition, HIV- 1 compartmentalization was revealed in gut, renal system and blood in one infected...
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Báo cáo y học: "Seroprevalence of hepatitis B and C virus in HIV-1 and HIV-2 infected Gambians" pps
... (16 .7) 42 (93.3) 0. 31 0.54 < 0.00 01 0 .17 0. 71 0.36 HIV- 1 25 (17 .6) (36.0) 11 7 (78.5) 16 (10 .1) (18 .8) 10 9 (76.8)* HIV- 2 (10 .3) (0.0) 24 (85.7) 24 (11 .1) (17 .4) 17 4 (89.2)* Dual Infection P-value ... 3/26 (11 .5%) * The ELISA positive individuals in the AIDS group include 24 /14 2 (16 .9%) HIV1 , 6/29 (20 .1% ) HIV- and 7 /19 ) (36.8%) HIV- Duals compared to 8 /15 7 (5.0%) HIV- 1, 18 / 215 (8.3%) HIV- and ... 2.2 × 10 0.83 0. 81 14 (58.3) 2.2 × 10 2 45-93 years P-value difference (33.3) 1. 9 × 10 (40.0) 2.0 × 10 3 0. 31 0.30 0 .12 0.53 ( 21. 4) 1. 1 × 10 4 17 (40.4)* 4.3 × 10 2 (14 .2) (18 .5)* 2 .1 × 10 3 HIV Status...
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Báo cáo y học: "Endogenous TGF-β activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells" docx
... unexpected finding that HIV infection results in an increase in Foxp3 expression in TCR activated CD25- T cells compared to those without HIV infection uncovers a link between HIV infection and induction ... TGF- 1 that are provided with the kit Flow cytometric staining The cells were re-suspended in PBS containing 1% BSA and 0 .1% sodium azide For the staining of cell surface markers, cells were incubated ... - T cells HIV infection upregulated Foxp3 expression in TCR activated CD4+CD25- T cells A Purified CD4+CD25- T cells were infected with HIV1 (HIV NLA-3) and cultured with anti-CD3 and anti-CD28...
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Báo cáo y học: "Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway" pot
... Cell line and treatment 0h 24 h 48 h J1 .1 Cells J1 .1 Cells + TNF α U1 Cells U1 Cells + PMA 14 .07 ± 0. 01 14.08 ± 0. 01 1.06 ± 0.03 1. 05 ± 0.03 14 .14 ± 0.05 12 .86 ± 0.90 1. 60 ± 0.03 51. 96 ± 9.20 18 .26 ... expression in uninfected or HIV persistently -infected cell lines MMP induction and Bcl-2 and Bax expression in uninfected or HIV persistently -infected cell lines H9 and H9/ HTLVIIIB (A) and Jurkat and ... apoptosis in uninfected and HIV persistently -infected cells H9 and H9/HTLVIIIB (A) and Jurkat and J1 .1 (B) cells were incubated with 20 g/ml or 40 ng/ml of CH 11, an anti-Fas activating antibody...
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Báo cáo khoa học: Peptides that bind the HIV-1 integrase and modulate its enzymatic activity – kinetic studies and mode of action pptx
... 16 217 6 16 618 0 17 018 4 17 418 8 18 219 6 18 6200 210 224 214 228 218 232 222236 238252 242256 246260 HIV IN residues 9 410 7 9 811 6 12 614 5 13 014 9 13 915 3 15 116 5 16 317 7 16 718 1 17 919 3 18 72 01 1 912 05 19 5209 223237 ... 56 71 5678 5679 5680 56 81 5682 5683 5685 5686 5692 5693 5694 5695 5699 5700 57 01 a Sequence NIH no 3852 4256 6276 6680 7084 8296 9 410 8 9 811 2 11 012 4 11 813 2 12 213 6 12 614 0 15 416 8 15 817 2 16 217 6 16 618 0 ... Sci 31, 9 810 5 49 Engelman A, Mizuuchi K & Craigie R (19 91) HIV- 1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer Cell 67, 12 111 2 21 FEBS Journal 278 (2 011 ) 316 330 ê 2 010 ...
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Báo cáo khoa học: HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment ppt
... N-f/C-a/C-a/C-e 11 0.4 11 2.6 97.8 92.8 96.0 10 5.3 10 5.5 10 8 .1 106.6 10 5.6 11 9 .1 106.2 10 8.0 71. 7 61 40 36 36 33 69 90 56 61 55 77 91 13 228 215 15 9 36 15 9 12 7 17 2 300 263 216 16 4 243 293 12 5 3.7 5.3 4.4 4 .1 ... (kcalÆmol )1) DHvH (kcalÆmol )1) DHvH/DHcal Reversibility (%) 11 0.4 11 9.5 10 9 .1 109 .1 112 .6 93.3 10 6.4 11 1.8 61 21 94 91 38 71 32 41 228 16 5 308 303 2 01 134 218 19 1 3.7 7.8 3.3 3.3 5.3 1. 9 6.8 4.6 ... (kcalÆmol )1) DHvH (kcalÆmol )1) DHvH/DHcal Reversibility (%) NC1 NC2 CN1 CN2 CN3 A30-D78_N 113 -K154 A30-K77_W 117 -K154 W 117 -K154_A30-K77 W 117 -A156_A30-K77 W 117 -W159_A30-K77 91. 0 86.5 10 1.9 10 6.8 11 2.5 10 3...
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Báo cáo hóa học: " Human Immunodeficiency Virus type 1 in seronegative infants born to HIV-1-infected mothers" doc
... http://www.virologyj.com/content/3 /1/ 52 infected persons and infants born to HIV- 1- infected mothers [3-6] In case of the pediatric infections some of these children appear to have eliminated virus -infected cells [3], ... Courpotin C, Dormont D: Clearance of HIV infection in 12 perinatally infected children: clinical, virological and immunological data AIDS 19 95, 9:F19-F26 Newell ML, Dunn D, De Maria A, Ferrazin A, ... MexP 11. 2PBMCclone2 HivSweden TPVIIIVenezuela MexP4.3PBMCclone3 E9USA 10 0 99 P1b P1a VE25AVenezuela MexP2.2PBMCclone2 consensusC 10 0 consensusE HIV- 1pCM235-4USA consensusA URTR35Uruguay 10 0 ARMA159Argentina...
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Báo cáo y học: "Lipoprotein levels and cardiovascular risk in HIV-infected and uninfected Rwandan women" docx
... prospective cohort study of HIV- infected and uninfected Rwandan women investigating the effectiveness and toxicity of antiretroviral therapy In 2005, 710 HIV- infected and 226 HIV- uninfected women were ... Lipoprotein Levels Mean (Standard Deviation) Total Body Fat in Kilograms P-value ≤ 7.4 7.4 to 11 .8 11 .8 to 17 .4 11 3 13 5 13 5 11 8 LDL 58.5 (28 .1) 66 .1 (28.2) 66.3 (27.3) 77.7 (30 .1) HDL 42.7 (16 .5) ... 20.9 (19 .0,23 .1) 0.068 12 .1 (7.9, 16 .4) 0.43 Body Mass Index (Kg/m2) Median (IQR) 20.6 (18 .6,23.5) Total Body Fat (Kg) Median (IQR) 11 .4 (6.6, 19 .0) 12 .0 (7.9, 17 .0) 0.95 11 .4 (7.9, 16 .5) 12 .1 (7.75,...
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