cav 1 ko mice a new preclinical model to study the role of stromal cav 1 in cancer pathogenesis and progression

A work force model to support the adoption of best practice care in chronic diseases – a missing piece in clinical guideline implementation pot

Ngày tải lên : 11/08/2014, 05:21

... knowledge of clinical practice guideline by clinicians This requires that guidelines are written in a way that is clear to clinicians and translatable into actions and an effective dissemination strategy ... established as part of model implementation to inform the sets of assumptions incorporated into the modelling The performance of the model is to be assessed in the first instance in terms of capacity ... Australia Adelaide; 19 99 Australian Institute of Health and Welfare (AIHW): Diabetes management and the allied health workforce: An overview of workforce mapping techniques and related data issues...

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báo cáo khoa học: " A work force model to support the adoption of best practice care in chronic diseases – a missing piece in clinical guideline implementation" ppt

Ngày tải lên : 11/08/2014, 16:21

... knowledge of clinical practice guideline by clinicians This requires that guidelines are written in a way that is clear to clinicians and translatable into actions and an effective dissemination strategy ... established as part of model implementation to inform the sets of assumptions incorporated into the modelling The performance of the model is to be assessed in the first instance in terms of capacity ... Australia Adelaide; 19 99 Australian Institute of Health and Welfare (AIHW): Diabetes management and the allied health workforce: An overview of workforce mapping techniques and related data issues...

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A Single-Molecule Perspective on the Role of Solvent Hydrogen Bonds in Protein Folding and Chemical Reactions pptx

Ngày tải lên : 22/03/2014, 18:20

... unfolding the I27 protein in D2O The pulling coordinate for the separating b-strands is defined as the distance between the first amino acid of strand A (Y9) and the last amino acid of strand ... we define the pulling coordinate for the A and G b-strands as the distance between the first amino acid of strand A (Y9) and the last amino acid of strand G (K87) This distance, x(Y9)ÀxACHTUNGRE(K87), ... bridging the A and G b-strands of the I27 protein during the main unfolding barrier.[39] To further validate this view and gain insight into the role of solvent hydrogen bonds in protein unfolding,...

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báo cáo hóa học:" A lifeline to treatment: the role of Indian generic manufacturers in supplying antiretroviral medicines to developing countries" pptx

Ngày tải lên : 20/06/2014, 08:20

... study, participated in data cleaning and data analysis, and was the lead author on this paper ED performed data cleaning and data analysis SM contributed to data analysis, writing of the manuscript, ... HIV/AIDS interventions and the 20 01 WTO Doha Declaration on TRIPS and Public Health [25] Rather than agreeing to inappropriate intellectual property obligations, India and its trade partners - along ... Mechanism, the Global Fund to Fight AIDS, Tuberculosis and Malaria’s Price & Quality Reporting Tool, and UNITAID as provided by the Clinton Health Access Initiative [11 -14 ] Antiretroviral transactional...

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Applied TPB model to study the intention of returning tourists in Jinju, South Korea

Ngày tải lên : 06/08/2016, 20:50

... Tsai, “How destination image and evaluative factors affect behavioural intentions?” Tourism Management, vol 28, pp 11 15 -11 22, 2007 [2] P A LaBarbera and D Mazursky, A longitudinal assessment of ... on the measurement scales of TPB (Ajzen, 19 88, 19 91) BBs of the push and pull motivation in travel were adapted from the study by Zhang and Lam (19 99) According to Ajzen and Fishbein (19 80), new ... related to travel intention According to the TPB, behavioral intention to act in a certain way is the immediate determinant of a behavior (Ajzen, 19 85) When there is an opportunity to act, the intention...

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The Weapons Mix Problem - A Math Model to Quantify the Effects of Internetting of Fires to the Future Force pptx

Ngày tải lên : 23/03/2014, 02:20

... the heart of the IOF Allocator and its implementation are included in Appendixes A and B Here we will cover the details of the data and constraints in the model The allocation tool maximizes the ... also may lead to an overestimation of the damage to targeted systems) This too was not a limitation to the IOF Allocator but rather of the incoming data Finally, the formulation is one-sided and ... explicitly model blue losses The Allocator is a planning device and, insofar as the data can be assumed to be the best possible at the time of the decision, a reasonable analysis may be to understand the...

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INFLUENTIAL MARKETING: A NEW DIRECT MARKETING STRATEGY ADDRESSING THE EXISTENCE OF VOLUNTARY BUYERS doc

Ngày tải lên : 23/03/2014, 04:21

... a random subset of the majority class is used in addition to the minority class Training samples of the majority class are randomly eliminated until the ratio of the majority and minority classes ... used in the thesis are discussed 2 .1 Classification in Data Mining Data mining is the process of extracting useful patterns or relationships from large data sets Major sub areas of data mining include ... reach a preset value, usually close to A disadvantage of under-sampling is that it reduces the data available for training In over-sampling, training samples of the minority class is over-sampled...

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Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot

Ngày tải lên : 19/06/2014, 08:20

... PBS Intraperitoneal injections of PBS or cyclophosphamide were administered on days 1, +1, and +3 after viral inoculation Statistical analysis Analysis of numerical data and statistical analyses ... http://www.virologyj.com/content/2 /1/ 56 Laboratory Animals Prior to ocular inoculation, mice were anaesthetized by intraperitoneal (i.p.) administration of xylazine (6.6 mg/kg) and ketamine (10 0 mg/kg) Mice were inoculated ... http://www.virologyj.com/content/2 /1/ 56 Figure Stat on innate resistance to HSV -1 Effect of7 Effect of Stat on innate resistance to HSV -1 Wild-type (strain 12 9) mice, rag2-/- mice, stat1-/- mice, and rag2-/-stat1- /mice were inoculated...

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báo cáo hóa học:" Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot

Ngày tải lên : 20/06/2014, 04:20

... PBS Intraperitoneal injections of PBS or cyclophosphamide were administered on days 1, +1, and +3 after viral inoculation Statistical analysis Analysis of numerical data and statistical analyses ... http://www.virologyj.com/content/2 /1/ 56 Laboratory Animals Prior to ocular inoculation, mice were anaesthetized by intraperitoneal (i.p.) administration of xylazine (6.6 mg/kg) and ketamine (10 0 mg/kg) Mice were inoculated ... http://www.virologyj.com/content/2 /1/ 56 Figure Stat on innate resistance to HSV -1 Effect of7 Effect of Stat on innate resistance to HSV -1 Wild-type (strain 12 9) mice, rag2-/- mice, stat1-/- mice, and rag2-/-stat1- /mice were inoculated...

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báo cáo hóa học: " A tool to measure the attributes of receiving IV therapy in a home versus hospital setting: the Multiple Sclerosis Relapse Management Scale (MSRMS)" pot

Ngày tải lên : 20/06/2014, 15:20

... collected the data, analysed and interpreted the data, and drafted the manuscript BP, JC, AJT and JH were involved in guiding the study including the design and coordination All authors contributed to ... who rate the care as excellent Rasch analysis in particular can aid the selection of these additional items Rasch analysis can also further assess the unidimensionality of the scales Finally, although ... missing data at weeks follow-up and were excluded from analysis The characteristics of the remaining 13 2 people are shown in Table and the psychometrics of the MSRMS in Tables 3, 4, and Data quality...

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báo cáo khoa học: "A Study to investigate the role of p27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma" pptx

Ngày tải lên : 09/08/2014, 01:24

... carcinomas [9] But the labelling index of cyclin D1 correlated with the pathological stage of the disease in invasive lobular carcinomas but not in invasive ductal carcinomas Another study evaluated ... Taniyama Y, Nagura H, Matsunaga G, Takehana K, Kimura M, Silverberg SG: Immunolocalization of cyclins D and E and cyclin dependent kinase (cdk) and in human breast carcinoma Anticancer Res 19 97, ... spread and vascular invasion with distant metastases free survival (MFS) in all invasive carcinomas and the subgroup of IDC in an univariate analysis However, there was no significant association...

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Báo cáo khoa học: "The role of adjuvant pelvic radiotherapy in rectal cancer with synchronous liver metastasis: a retrospective study" doc

Ngày tải lên : 09/08/2014, 09:20

... A, Charnley RM, Scheele J: Factors influencing the natural history of colorectal liver metastases Lancet 19 94, 343 :14 05 -14 10 17 Thomas PR, Lindblad AS: Adjuvant postoperative radiotherapy and ... colon and rectal cancer Seminars in oncology 19 91, 18 : 411 -420 12 Pettavel J: Protracted arterial chemotherapy of liver tumors: an experience of 10 7 cases over a 12 -year period Progress in Clinical ... Table Statistical analysis The primary endpoint of the study was pelvic failure free survival (PFFS) PFFS was defined as any relapse within the pelvic cavity The PFFS rate and overall actuarial...

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cáo khoa học: " A knowledge translation collaborative to improve the use of therapeutic hypothermia in post-cardiac arrest patients: protocol for a stepped wedge randomized trial" pdf

Ngày tải lên : 10/08/2014, 10:23

... regions of the Province of Ontario, and have hospital bed capacities ranging from 19 to >600 and ICU bed capacities ranging from to 42 This sample also includes all of the adult teaching hospitals affiliated ... participating hospitals’ ED and ICU to introduce the SPARC collaborative goals and objectives, and to outline the rationale behind therapeutic hypothermia The passive phase will occur according to the ... each of the hospitals The data dictionary, containing all variables, definitions, and ranges specific to the study and abstraction instructions will be programmed into a touch icon that displays...

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cáo khoa học: " Developing a theory-based instrument to assess the impact of continuing professional development activities on clinical practice: a study protocol" doc

Ngày tải lên : 10/08/2014, 10:23

... encompasses continuing medical education (CME) [1] , plays an important role in maintaining and improving the quality and efficiency of the healthcare system [2] by translating evidence into clinical ... Québec, Canada 10 11 12 13 14 15 16 17 18 19 20 21 22 Authors’ contributions All authors collectively drafted the study protocol and approved the final manuscript FL is its guarantor Competing interests ... of 10 items A minimum of 10 0 data entries are needed for an exploratory factor analysis (EFA) [19 ] Also, a minimum of 10 data entries are needed per parameter to make estimations for confirmatory...

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báo cáo khoa học: "Helping hands: A cluster randomised trial to evaluate the effectiveness of two different strategies for promoting hand hygiene in hospital nurses" ppsx

Ngày tải lên : 10/08/2014, 11:20

... handwashing and hand antisepsis in healthcare settings Am J Infect Control 19 95, 23:2 51- 269 Lautenbach E: Practices to Improve Handwashing Compliance In Making healthcare safer: a critical analysis ... task and before from the patient flora to other surfaces in patient flora to contacting another the healthcare setting the rest of the patient healthcare environment and infection of other patient ... considerations, and offered advice on the statistical analysis EA is the team’s expert in economic evaluations and was involved in the design of the study TVA is the general supervisor of the study and...

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Báo cáo khoa học: "A Clinical review: Molecular mechanisms underlying the role of antithrombin in sepsis" docx

Ngày tải lên : 12/08/2014, 23:21

... thrombin and factor Xa but also factor IXa, and it weakly inhibits factors XIa and XIIa, trypsin, plasmin, kallikrein and factor VIIa [15 -17 ,20, 21] This broad spectrum of inhibition makes antithrombin ... Both of these inhibit serine proteases and cofactors/activated coagulation factors [1] Antithrombin is a 58 kDa glycoprotein that is composed of a single amino acid chain with a plasma concentration ... remaining 5 15 % of circulating antithrombins, of the β isoform, lack glycosylation at asparagine 13 5, which results in their 3- to 10 -fold greater affinity for heparin [22] Anticoagulation Heparin...

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Báo cáo y học: " The Basic Immune Simulator: An agent-based model to study the interactions between innate and adaptive immunity" doc

Ngày tải lên : 13/08/2014, 16:21

... intellectual content The living authors, VAF and GCA, read and approved the final manuscript Additional material Additional file State diagram key A key to the symbols used in all of the state diagrams ... complex, and the interaction between the two represents another level of intricate, non-linear and potentially paradoxical behavior [7 ,16 ,19 ] In order to aid in the qualitative characterization and ... Portals are a means of transferring agents and signals from one zone to another They are randomly placed in Zones and The variation and uncertainty of the time spent by immune cells in the areas represented...

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Báo cáo y học: "The role of emergency medicine physicians in trauma care in North America: evolution of a specialty" pps

Ngày tải lên : 13/08/2014, 23:20

... pursue advanced training in Critical Care leading to a specialty board exam The role of these physicians in trauma care is not well known In US and Canadian trauma centers this is a relatively new ... trauma care J Trauma 19 99, 46:757-763 discussion 763–754 The Trauma Association of Canada: Trauma System Accreditation Guidelines Toronto, Canada: Trauma Association of Canada; 2003 Ahmed JM, Tallon ... with trauma care than those whose training allows exposure to trauma only as part of their general EM training, particularly if a separate trauma team responds for trauma activations In smaller...

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Báo cáo y học: " Using Geographic Information Systems (GIS) to assess the role of the built environment in influencing obesity: a glossary" pptx

Ngày tải lên : 14/08/2014, 08:20

... and AMK contributed to the study design and the redrafting of the paper All authors read and approved the final version of the final paper Competing interests The authors declare that they have ... while at the individuallevel factors such as age, gender, access to a motor vehicle, and/ or perception of distance and safety all influence the ability and willingness of an individual to access the ... primary and secondary data Page of often require manual geocoding to transpose the data into a GIS compatible format Geocoding Geocoding is the process of matching raw address information (e.g the...

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Social Impact Bonds - A promising new financing model to accelerate social innovation and improve government performance pot

Ngày tải lên : 22/03/2014, 20:20

... Case Management,” prepared by Mathematica Policy Research Inc for the Office of the Assistant Secretary for Planning and Evaluation, U.S Department of Health and Human Services (Washington: 2003), ... operating capital only if private investors are convinced that a program’s model and management team are likely to achieve the performance targets The private investors thus perform an important ... payments are made to investors only to the extent that the programs reduce costs to the government In a job-training program that increased participant earnings, for example, payment to investors...

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