calorimetry as a new method to monitor human plasma in melanoma patients with regional lymph node or distal metastases
TYPE 1 DIABETES – COMPLICATIONS, PATHOGENESIS, AND ALTERNATIVE TREATMENTS docx
... complications can be subdivided into macrovascular and microvascular complications Cardiovascular disease is the major macrovascular complication and includes mainly myocardial infarction and stroke ... retinopathy and angiopathy (Peppa & Vlassara, 2005; Yamagishi et al., 2008; Goh & Cooper, 2008; Karasu, 2010) Higher plasma levels of AGEs are associated also with incident cardiovascular disease and all-cause ... Stress in Type Diabetes Patients in Relation to Circulating TGF-Beta1, VCAM-1 and Diabetic Vascular Complications 1Institute Vladimir Jakus1, Jana Kostolanska2, Dagmar Michalkova1 and Michal Sapak3...
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báo cáo hóa học:" The cross-sectional associations between sense of coherence and diabetic microvascular complications, glycaemic control, and patients’ conceptions of type 1 diabetes" pot
... dependent variables in analyses The questionnaire’s reliability was assessed calculating Cronbach’s a, and a > 0.60 was deemed acceptable Factorial analysis of variance was used to study the associations ... (Länsimäki): R Ahonen, M Ivaska-Suomela and A Jauhiainen; (Martinlaakso): M Laine, T Pellonpää and R Puranen; (Myyrmäki): A Airas, J Laakso and K Rautavaara; (Rekola): M Erola and E Jatkola; (Tikkurila): ... Raahe Hospital: A Holma, M Honkala, A Tuomivaara and R Vainionpää; Rauma Hospital: K Laine, K Saarinen and T Salminen; Riihimäki Hospital: P Aalto, E Immonen and L Juurinen; Salo Hospital: A Alanko,...
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báo cáo hóa học: " Anandamide inhibits Theiler’s virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1 receptors" pdf
... in cerebral vasculature by anandamide provides a new mechanism that may explain the therapeutic action of increased anandamide tone in neuroinflammatory diseases like MS Additional material Additional ... Heilman D, Morsey B, Potula R, Haorah J, Persidsky Y: Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses Rho GTPases in human brain microvascular endothelial ... stained with AM-calcein adhered to the brain endothelial cell monolayer in each case and phase contrast microphotographs of brain endothelial monolayer merged with immunofluorescence microphotographs...
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Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps
... need for intravenous access devices for the administration of cancer therapy has increased proportionally with the increasing number of patients diagnosed with cancer The percutaneous approach to ... as interventional ultrasound in clinical practice for patient management (diagnosis, staging, restaging and follow-up) for almost 25 years [21-27], this procedure was early applied as a guidance ... because of anatomical variation or difficult veins (small veins; no palpable landmarkers) Anatomical variations of the internal jugular vein were found in 8% of patients studied with ultrasound-guided...
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VASCULAR COMPLICATIONS OF DIABETES - PART 1 ppt
... developing coronary heart disease as those with normal glucose tolerance In addition, the association of diabetes (particularly type 2) with multiple vascular risk factors such as hypertension and ... retinopathy after a mean of 11.5 years compared to 14.7 years in those with normoalbuminuria The chance of remaining free from background retinopathy after 12 years was < 25% in patients with ... protein kinase C (PKC) explains the basis of a major new pathway responsible for hyperglycaemia-induced vascular injury Recent clinical trials have suggested that inhibition of PKC-β is an effective...
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Báo cáo y học: "Relationship between inflammatory markers, metabolic and anthropometric variables in the Caribbean type 2 diabetic patients with and without microvascular complications" pptx
... that SSA can be used as a marker for cardiovascular risk In addition to sialic acid another inflammatory marker was assessed, C- reactive protein (CRP) There was an insignificant increase in ... Earle K, Morocutti A, Yip J, Viberti GC, Pickup JC: Serum sialic acid a risk factor for cardiovascular disease is increased in IDDM patients with microalbuminuria and clinical proteinuria Diabetes ... use as a potential inflammatory marker for diabetes mellitus [11] Previous reports have also indicated that serum sialic acid (SSA) concentrations were associated with an increased risk of cardiovascular...
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Báo cáo y học: "Characterization of N200 and P300: Selected Studies of the Event-Related Potential Salil H. Patel 1 and Pierre N. Azzam 2"
... Supplementary Motor Cortex (SMC) or cingulate gyrus as generators for the Novelty P3 [42] The P3b component has been proposed to index memory storage as well as serving as a link between stimulus characteristics ... elicited N2b was found to continuously increase in latency and decrease in amplitude with increasing age These findings suggest the constancy of automatic distinction and analytical processes ... Sci 2005 with spreading and advanced disease For instance, anterior P 3a is attenuated in amplitude in patients with Parkinson’s Disease [96], with concomitant P300b anomalies [97] Furthermore, differences...
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Agile Web Application Development with Yii 1.1 and PHP5
... abstract database access in an object-oriented fashion Each AR object in Yii is an instance of CActiveRecord or its child class that wraps a single row in a database table or view, encapsulates all ... is actually working code with form validations, as well as username and password credential validation and authentication Using either demo/demo or admin/admin as the username/password combination ... Acquisition Editor Usha Iyer Development Editors Dhwani Devater Reshma Sundaresan Technical Editors Aditya Belpathak Hyacintha D'Souza Indexer Hemangini Bari Project Coordinator Prasad Rai Proofreader...
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listen and speaking 1 and 2
... they have a rising or falling intonation a rising b falling a rising b falling a rising b falling a rising b falling a rising b falling a rising b falling a rising b falling a rising b falling a ... that means the same a Rachel isn’t the same height as Yoko b Rachel is as tall as Yoko a His car isn’t as bad as mine b My car is in better shape than his is a Texas is farther than Florida is ... the symptoms you hear You may hear more than one symptom The speaker has a headache stomachache toothache The speaker has a fever cough headache The speaker has a sore back sore arm sore neck...
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Tài liệu ADC’s HDSL Interface Panel combines HDSL termination, DSX-1 and DSX-3 into a single shelf doc
... routing paths • Parking-lot available with terminators • Parking-lot feature provides cross-connect functionality at interconnect price • Parking-lot feature ensures connector cleanliness is maintained ... specifications by contacting our headquarters office in Minneapolis ADC Telecommunications, Inc views its patent portfolio as an important corporate asset and vigorously enforces its patents Products ... Preterminated with OSP cable; loose tube or ribbon, armored or dielectric - Bend radius protection • Angled or flat polish connectors - Slack storage • Uses ADC high performance connectors - Clear...
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Tài liệu Chapter 4: Configuring Layer 1 and Layer 2 Features docx
... dynamically builds and maintains the DHCP snooping database using information extracted from intercepted DHCP messages The database contains an entry for each untrusted host with a leased IP address ... interface interface-id | interface interface-id] [detail] Displays information about one or more service instances: If a service instance ID and interface are specified, only data pertaining to that ... interface interface-id | interface interface-id] [detail] Displays information about one or more service instances: If a service instance ID and interface are specified, only data pertaining to that...
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Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx
... GCTCAGTGGTGGA-3 and 5-CTGAGGGAAGCAAG AATGGA-3, OXI1 (At3g25250): 5-GACGAGATTATC AGATTTTACGC-3 and 5-AACTGGTGAAGCGGAAG AGAC-3, PTI1-4 (At2g47060): 5-CCCCAAAGAAAATG AGTTGCT-3 and 5-GCATCATTTCCTGGAGGAAAG-3 ... substrate to assess the kinase activity and GST alone was used as a negative control The top panel shows the kinase assay visualized by autoradiography and the bottom panel shows the Coomassie ... the top panel shows the kinase assay visualized by autoradiography and the bottom panel shows the Coomassie Brilliant Blue-stained SDS ⁄ PAGE The in vitro kinase assays in (A) and (B) were repeated...
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Tài liệu Báo cáo khoa học: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor pdf
... inhibitory activity than HAI-1–NK1 Hepatocyte growth factor activator inhibitor type (HAI-2), also known as placental bikunin, is also a transmembrane Kunitz-type serine protease inhibitor [15,16] ... hepatocyte growth factor activator (HGFA), a blood coagulation factor XII-like serine protease that converts pro-hepatocyte growth factor (pro-HGF) to the active form [4] HAI-1 was also isolated ... factor activator Eur J Biochem 229, 257–261 Miyazawa K, Tsubouchi H, Naka D, Takahashi K, Okigaki M, Arakaki N, Nakayama H, Hirono S, Sakiyama O, Takahashi K et al (1989) Molecular cloning and...
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Tài liệu Báo cáo khoa học: The two Caenorhabditis elegans metallothioneins (CeMT-1 and CeMT-2) discriminate between essential zinc and toxic cadmium docx
... crystal monochromator detuned to 70% transmission to minimize harmonic contamination The monochromator was calibrated at each energy value using a 15 lm cadmium foil or a 10 lm zinc foil Data were ... CeMT-2 was significantly larger than that for zinc binding, and was close to the value for human MT-2 measured under similar conditions [34] Remarkably, this was not the case for CeMT-1 Although ... Fig XANES profiles in wild-type nematodes and standards Cd XANES spectra (A) and Zn XANES spectra (B) For cadmium, a minor monochromator drift during data collection made it necessary to correct...
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Tài liệu Báo cáo khoa học: Synergistic activation of signalling to extracellular signal-regulated kinases 1 and 2 by epidermal growth factor and 4b-phorbol 12-myristate 13-acetate pptx
... surface In addition it causes a decreased EGF binding a nity and tyrosine kinase activity of the receptor Also shown are the stimulators and inhibitors (depicted in red) used in this study EGF was ... by EGF, and observed a biphasic pattern consisting of a first rapid peak and relatively low and a broad second peak developing into what we refer to as a quasi-steady state The first peak has been ... fibroblasts after stimulation with serotonin and basic fibroblast growth factor for 120 [46] In platelets, pretreatment with thrombopoietin and stimulation with a- thrombin led to a 30% phosphorylation...
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Tài liệu Báo cáo khoa học: Characterization of promoter 3 of the human thromboxane A2 receptor gene A functional AP-1 and octamer motif are required for basal promoter activity docx
... element with the sequence aGCAAAtc to aGCAAGtc (core bases shown in uppercase letters) centered at )105 within Prm3 was performed using the mutator primers Kin193 (5¢-dGAATTAATCACAAGC AAGTCTTCTCTCGCCTCCCAG-3¢; ... 5¢-dGAGAGGTACCAGCTACTTACACTGAAA TGCAG-3¢, corresponding to NTs )140 to )118) (6) Prm3ac; pGL3b:Prm3ac & pGL3e:Prm3ac (Primer Kin188; 5¢-dGAGAGGTACCGAATTAATCACAAGCAA ATCTTCTC-3¢, corresponding to NTs )119 to ... of TPa and TPb to haemostasis and possibly to vascular disease Experimental procedures Materials pGL3Basic, pGL3Enhancer, pRL-Thymidine Kinase (pRL-TK) and Dual LuciferaseÒ Reporter Assay System...
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Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis docx
... decrease in plasmin formation, to a decrease in plasmin binding or to a combination of the two We demonstrate that both mAb 34D3 and mAb A1 0.2 inhibit plasmin binding to cells (Fig 5A) and fibrin ... mediates initial binding and activation whereas K4-LBS is secondarily required to reinforce plasmin(ogen) anchorage In contrast, in Lys-Pg as in plasmin, K1- and K4-LBS act as independent and ... Montes R, Paramo JA, Angles-Cano E & Rocha E (1996) Development and clinical application of a new ELISA assay to determine plasmin-alpha2-antiplasmin complexes in plasma Br J Haematol 92, 979–985...
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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf
... TGT GAT GC GCA TCA CAG TCT GTG GTA CCT TAC AGG AGG AG GTG GCG TCT GAG GTA CCA ATG CAA ATG CGC GCG CAT TTG CAT TGG TAC CTC AGA CGC CAC GAG ACT GTG ATG CGG TAC CTC CCG CCC TTT C GAA AAG GGC GGG AGG ... TAC CGC ATC ACA GTC TC GCA AAT GCG CCA GGT ACC TTC TGG GAA CTC GAG TTC CCA GAA GGT ACC TGG CGC ATT TGC CCG CCC TTT TGA GGT ACC AGA GAA CGC CTG CAG GCG TTC TCT GGT ACC TCA AAA GGG CGG CTG GGA ACT ... of age were purchased from Jackson Laboratories (Bar Harbor, ME), and were housed in the animal facility at the Toronto Hospital Research Institute, University of Toronto Cells Peritoneal macrophages...
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Tài liệu Báo cáo Y học: Binding of gelsolin domain 2 to actin An actin interface distinct from that of gelsolin domain 1 and from ADF/cofilin pptx
... using alkaline phosphatase-labelled anti-IgG antibodies (1 : 1000) or alkaline phosphatase-labelled streptavidin (1 : 1000) Control assays were carried out in wells saturated with gelatin and gelatin ... ) Binding was detected by using anti-cofilin antibodies and was monitored at 405 nm Fig 10 Binding of gelsolin domain S2 to actin (A) FITC labelled gelsolin domain S2 (0.26 mM ) was mixed with ... gelsolin bind actin, cross-link to F-actin and compete with S2–3 for binding to F-actin [33] A deletion study [32] concluded that a mutant 173– 266 was not able to bind actin Additional data on...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose