c myrip as a rab27a myos in va viia and actin binding protein
Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx
... AR N /C interaction Coactivator competition ABPs HDAC chromatin condensation Actin Coactivators HAT AR AR ABPs AR AR Pol II ARE AR HSP AR nuclear translocation Actin ABPs Fig Regulation of androgen ... sequestering actin monomers, and Actin and ABPs in transcription regulation can sever and cap actin filaments [1] Nishimura et al [100] identified gelsolin as an AR-interacting protein that can enhance ... AR, and interferes with the binding of the coactivator TIF2 2676 Indirect Coactivator Increases interaction frequency with the AR Direct N- and C- Terminal Coactivator AR cytoplasmic trafficking...
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Tài liệu Báo cáo Y học: Use of site-specific recombination as a probe of nucleoprotein complex formation in chromatin Micha Schwikardi and Peter Droge ¨ potx
... cotransfected with an expression vector for a phage l integrase mutant was set as 100% In each case, data were collected from six separate transfection assays, each employing two wells containing ... the N-terminal tails of histones are thought to render chromatin more accessible for DNA -binding proteins In fact, DNA transactions such as V(D)J recombination and transcription are enhanced when ... first analyzed recombination in cell line TRE2/3 which contains a single copy of the vector The analysis was performed in the absence of doxycyclin, i.e the TRE-CMV promoter is active and transcription...
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Báo cáo y học: "Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations" ppt
... of data CA performed the statistical analysis and the clinical associations AS participated in the analysis and interpretation of data and in the revision of the manuscript RR participated in ... associate with actin- based structures such as the contractile ring and stress fibers [22,23] The septins are a family of cytoskeletal GTPases that play an essential role in cytokinesis in yeast ... Margutti P, Ortona E, Vaccari S, Barca S, Riganò R, Teggi A, Muhschlegel F, Frosch M, Siracusano A: Cloning and expression of a cDNA encoding an elongation factor 1β/δ protein from Echinococcus...
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Báo cáo y học: "Serum cystatin C concentration as a marker of acute renal dysfunction in critically ill patients" doc
... cystatin C and serum creatinine for identifying renal dysfunction was evaluated using receiver operating characteristic curve analysis, and the data are expressed as area under the curve (AUC; ... serum sample to calculate the creatinine clearance (CCr) using the following formula: CCr (ml/min) = (urine volume × urine creatinine)/(serum creatinine × 1440) Serum creatinine values were obtained ... creatiR140 A decline in CCr was followed by an increase in levels of serum creatinine and serum cystatin C (Fig 1) The inverse of the serum cystatin C and serum creatinine levels were plotted against...
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Motivation as a Contributing Factor in Second Language Acquisition
... successful acquisition of a second language At the same time it is necessary to view motivation as one of a number of variables in an intricate model of interrelated individual and situational factors ... heavy emphasis on vocabulary and grammar Many foreign texts, however, which have been designed for EFL, and specifically the Japanese market, often contain topics which can create a great deal ... setting or context in which learning takes place Two contexts are identified, namely formal instruction within the classroom and unstructured language acquisition in a natural setting Depending...
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A contrastive analysis of encouraging as a speech act in english and vietnamese
... learning of communication in a foreign language and partly in Communicative encouraging in English and Vietnamese as a speech act Language Teaching 1.3 SCOPE OF THE STUDY 1.2 AIMS AND OBJECTIVES ... theoretical bases about pragmatics, mentions and discusses speech acts Thomas, J (1995), “Meaning in interaction: An introduction to Pragmatics, Longman.” [73] This book accords a central place to ... Directives = speech acts that are to cause the hearer to take languages a particular action, e.g requests, commands and advice 2.2 THEORETICAL BACKGROUND * Commissives = speech acts that commit a...
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Reiteration as a cohesive device in news in brief on iraq war in english press = phép lặp làm phương tiện liên kết trong tin vắn về chiến tranh i rắc trên báo chí tiếng anh
... coherence can be obtained by various linguistic devices including grammatical and lexical ones However, it is traditionally the case that almost learners’ attention has been drawn onto grammatical devices ... Part C: Conclusion In this part, principal findings are summarized and some practical applications as well as some suggestions for further researches are provided Reiteration as a cohesive device ... Analysis came into being as a branch of linguistics, the term ‘discourse’ has been defined in different ways A discourse, according to David Nunan in the introduction of his Introducing Discourse...
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Tài liệu Supporting Children Learning English as a Second Language in the Early Years (birth to six years) docx
... Cubey, P, Hatherly, A, and Macartney, B 2000, Learning and teaching stories: Action research on evaluation in early childhood, New Zealand Council for Educational Research and Ministry of Education, ... Association, Richmond, Victoria, Australia Nyakatawa, S and Siraj-Blatchford, I 1994, ‘Bilingualism, biculturalism and learning in Early Years Classrooms’, in Blackledge, A (Ed), Teaching bilingual ... Learning English as a Second Language in the Early Years (birth to six years) but also includes the development of communicative aspects such as attracting and sustaining attention, managing interactions...
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Báo cáo khoa học: The hinge region operates as a stability switch in cGMP-dependent protein kinase Ia doc
... Richie-Jannetta R, Kotera J, Macdonald BA, Gibson RR, Trewhella J (2003) Mechanisms associated with cGMP binding and activation of cGMP-dependent protein kinase Proc Natl Acad Sci USA 100, 2380–2385 Zhao ... masses could be measured with an accuracy of a few Daltons, as depicted in Table For all three proteins, the expected theoretical masses matched to the measured masses, assuming, as described ... et al Kinetic characterization of mutants Determination of the activation constant (Ka) for cGMP on recombinant bovine wild-type PKG and R77L was adapted from Landgraf et al [4] and Dostmann...
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Báo cáo khoa học: The ‘pair of sugar tongs’ site on the non-catalytic domain C of barley a-amylase participates in substrate binding and activity potx
... 5Â-TTTGGTACCTCAGTTCTTCTCCCAGA CGGCGTA-3Â as antisense primer Mutant cDNA was amplied using 5Â-TTTGAATTCCATGGGGAAGAACG GCAGC-3Â as sense orientation primer and a puried megaprimer Pfu DNA polymerase (Stratagene, ... Y38 0A, 5Â-GATCGGGTCCAGGGCCGACGTC -GG-3Â; Y380M, 5Â-GATCGGGTCCAGGATGGACGT CGG-3Â; Y380F, 5Â-GATCGGGTCCAGGTTCGAC GTCGG-3Â (underlined mutant codon) coding for the sense strand, and 5Â-TTTGGTACCTCAGTTCTTCTCCCAGA ... shown) and in complex with acarbose a pseudotetrasaccharide inhibitor whose rings A and B correspond to the valienamine and 4-amino-4,6-dideoxy -a- d-glucose units in acarviosine, and rings C and...
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Báo cáo khoa học: "Mutation and overexpression of p53 as a prognostic factor in canine mammary tumors" pptx
... inactivation occurred prior to invasion in breast carcinogenesis, with mutations being uniformly identified in ductal carcinoma in situ associated with p53-mutated invasive carcinomas Immunohistochemical ... or score Proliferative activity was examined by staining with an anti-Ki-67 specific antibody, MIB-1, and was evaluated separately in each case after counting at least 500 nuclei in 3-5 randomly ... slide A tumor sample was regarded as p53 positive if nuclear staining was clearly detected, but cytoplasmic staining alone was not recorded as positive Positively staining was evaluated semi-quantitatively...
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Báo cáo y học: "B cells as a therapeutic target in autoimmune disease" doc
... Interactions between T cells and B cells in rheumatoid arthritis Arthritis Res 2000, 2:457-463 Bernasconi NL, Traggiai E, Lanzavecchia A: Maintenance of serological memory by polyclonal activation ... thrombocytopenia, response rates are lower and range from 30 to 50% [12–14] These data confirm that, at least in some patients, plasma cells are not sufficient to maintain autoantibody levels and that continuous ... RA Initially, Edwards and Cambridge reported on five patients with refractory RA, all of whom had major improvement in disease activity and achieved responses meeting ACR 70 criteria (American...
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báo cáo khoa học: "A Study to investigate the role of p27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma" pptx
... Table p27 and cyclin E statistical associations p27 Cyclin E All invasive carcinomas Infiltrating duct carcinomas only All invasive carcinomas Infiltrating duct carcinomas only Distant metastases ... lobular carcinomas but not in invasive ductal carcinomas Another study evaluated the bio-molecular differences between ductal and lobular carcinomas in 190 in ductal and 67 lobular carcinomas [31] ... spread and vascular invasion for all invasive carcinomas However, cyclin E provides some prognostic value as there is a direct statistical association with the development of distant metastases in...
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Báo cáo y học: "Identification of citrullinated α-enolase as a candidate autoantigen in rheumatoid arthritis" doc
... protein was confirmed as α-enolase by immunoblotting with the goat anti-α-enolase antibody CAP1, adenyl cyclase-associated protein 1; EF1α, elongation factor 1α tides containing internal citrulline, ... Research & Therapy Vol No Kinloch et al Figure Figure Prevalencepatients and healthy controls lase in RA of antibodies against deiminated and undeiminated α-enolase in RA patients and healthy controls ... arthritis: clinical performance and biochemical aspects of an RA-specific marker Clin Chim Acta 2004, 350:17-34 van Gaalen FA, Linn-Rasker SP, van Venrooij WJ, de Jong BA, Breedveld FC, Verweij CL, Toes...
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Enterovirus type 71 2A protease functions as a transcriptional activator in yeast ppsx
... (5’-CATAATGACTGGGCAAACTCATCTACCACTGCTCAA-3’) L30/43 -AS 2AY -AS1 01 (5’-TTGAGCAGTGGTAGATGAGTTTGCCCAGTCATTATG-3’) (5’-CCGCTCGAGTTACTGATCATCCAACCACAGAAG-3’) 2A -AS3 01 (5’-GCTCTAGACTGATCATCCAACCACAGAAG-3’) ... (5’-GCTCTAGACTACTGCTCCATGGCTTCATCATC-3’) 2A -AS3 (5’-GCTCTAGACTGCTCCATGGCTTCATCATC-3’) C1 1 0A- S (5’-CCAGGGGATGCCGGTGGCATTCTTAGATGC-3’) C1 1 0A -AS (5’-AATGCCACCGGCATCCCCTGGTTCCGAATG-3’) L30/43-S (5’-CATAATGACTGGGCAAACTCATCTACCACTGCTCAA-3’) ... (5’-CTCTCACCATCCGGCTACTTAT-3’) PCBP2 -AS PTBP1-S (5’-GCTGCTTATGTCCTCTTCCAGT-3’) (5’-CTACATCCAGTTCTCCAACCAC-3’) PTBP1 -AS (5’-GCTGCTTATGTCCTCTTCCAGT-3’) RTN3-S (5’-ACTCTGTCCTCAGAAGCTTTCC-3’) RTN3-AS...
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Báo cáo y học: " Fetal bone as a foreign body in the urinary bladder: a case report" pot
... the patient, diagnosis and preparation of this case report: Zulifqar Ali, Irshad Ahmad and Zikria Rasheed of the Department of Surgery, Madina Teaching Hospital, Faisalabad, Pakistan; Saadia Hameed ... Department of Pathology, Madina Teaching Hospital and University Medical College Faisalabad, Pakistan; and Rana Qaiser Mehmood of the Department of Pathology, Punjab Medical College, Faisalabad, ... intestine and rectum is not an uncommon complication under these circumstances Trained birth attendants, female health workers and female health visitors have been trained and appointed in rural areas...
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Báo cáo y học: "Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature" pot
... http://jmedicalcasereports.com/jmedicalcasereports/article/view/9132 transcriptase, inducing an allosteric modification of the active site influencing enzyme performance [15] Collins et al., applied a ... quasispecies [5] Along a different line of evidence, Hatano et al recently demonstrated that failing NNRTI-based HAART regimens not confer clinical residual advantage, at variance with PIbased failing ... for six years as dominant quasispecies, in the absence of selective pressure, after administration of EFV for a year and a half In such a case, the authors postulated a possible eradication of...
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Báo cáo y học: " Health status and lifestyle factors as predictors of depression in middle-aged and elderly Japanese adults: a seven-year follow-up of the Komo-Ise cohort study" doc
... 34:881-888 41 Mino Y, Shigemi J, Otsu T, Ohta A, Tsuda T, Yasuda N, Babazono A, Yamamoto E: Smoking and mental health: cross-sectional and cohort studies in an occupational setting in Japan Prev Med ... depression in both men and women Having chronic diseases was a significant risk factor for depression in men, whereas poor perceived health was a significant risk factor in Table The number of analysis ... social acceptance of smoking, as well as in nicotine metabolism, might influence the risk of depression and suggested that smoking is less socially acceptable for women than for men in Mexico In...
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Báo cáo y học: " Electrical wire as a foreign body in a male urethra: a case report" ppsx
... impulsive behavior, self-punishing in nature that may aggravate to suicide [1] The psychiatric evaluation is controversial as many of these patients are psychologically normal [2] In our case, as there ... Editor -in- Chief of this journal Acknowledgements The authors state that there was no extra-institutional funding Andreas Petrolekas was a major contributor in writing the manuscript Constantinos Constantinides ... urethra is of erotic or sexual nature, especially masturbation or sexual gratification [1-4] A mental illness or drug intoxication may also be the reason Clinical presentation may vary from asymptomatic...
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Báo cáo y học: " Penicillium species as a rare isolate in tracheal granulation tissue: a case series" ppt
... resulting suspension was inoculated onto blood agar aerobically and anaerobically, Maconkey agar, Neomycin blood agar anaerobically with a metronidazole disc added on the streak cm away from the inoculum, ... Journal of Medical Case Reports 2008, 2:84 Case presentation Case A previously healthy 60-year-old male was intubated for a two-week period following myocardial infarction and as a consequence ... the inoculum, chocolate agar under 10% carbon dioxide (CO2) and Sabouraud's dextrose agar at 30 and 37 C The plates were incubated and were examined for growth after 2, and days incubation The...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25