b— bile salt synthesis
Báo cáo Y học: Functional analysis of the rat bile salt export pump gene promoter Regulation by bile acids, drugs and endogenous compounds potx
... promoter construct While most of the unconjugated bile acids exerted positive effects on Bsep reporter activity, the taurine conjugated bile salts taurocholic acid and tauroursocholic acid (TUDCA) ... intrinsic bile acid synthesis in HepG2 cells [26], namely of CDCA and CA further supports this concept The full length Bsep promoter was stimulated by a number of conjugated and unconjugated bile ... functional importance of this binding site for bile acid-mediated Bsep regulation Although conjugated bile acids are the predominant form found in bile [28] they were either weak stimulators of...
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Báo cáo Y học: Human bile salt-stimulated lipase has a high frequency of size variation due to a hypervariable region in exon 11 pot
... lipases, II: Bile salt- stimulated lipase Biochim Biophys Acta 369, 234±244 È Blackberg, L., Angquist, K.A., Hernell, O (1987) Bile- salt- stimuÈ lated lipase in human milk: evidence for its synthesis ... colipase-dependent lipase, and bile salt- stimulated lipase J Clin Invest 85, 1221±1226 Blackberg, L., Blind, P.J., Ljungberg, B., Hernell, O (1985) On the È source of bile salt- stimulated lipase in ... cholesterol esterase and bile salt- stimulated milk lipase FEBS Lett 276, 131±134 Baba, T., Downs, D., Jackson, K.W., Tang, J., Wang, C.-S (1991) Structure of human milk bile salt activated lipase...
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Advanced Organic Chemistry-PART B: Reactions and Synthesis
... Solid-Phase Synthesis 13.6.1 Solid-Phase Synthesis of Polypeptides 13.6.2 Solid-Phase Synthesis of Oligonucleotides Combinatorial Synthesis ... concludes with a discussion of solid-phase synthesis and its application in the synthesis of polypeptides and oligonucleotides, as well as to combinatorial synthesis The control of reactivity to ... 9.1.1 Synthesis of Organoboranes 9.1.2 Carbon±Carbon Bond-Forming Reactions of Organoboranes 9.2 Organosilicon Compounds 9.2.1 Synthesis...
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Tài liệu Báo cáo khoa học: a-Defensins increase lung fibroblast proliferation and collagen synthesis via the b-catenin signaling pathway doc
... enhanced proliferation and collagen synthesis in LL-86 lung fibroblasts (Figs S1 and S2), suggesting that a-defensin-induced increases in proliferation and collagen synthesis are a generalized phenomenon ... fibroblast proliferation and collagen synthesis To clarify whether b-catenin is responsible for defensin-induced increases in lung fibroblast proliferation and in collagen synthesis, the protein expression ... inflammatory lung diseases promote proliferation and collagen synthesis of lung fibroblasts The stimulatory effects of a-defensins on collagen synthesis reach a plateau at higher concentrations, whereas...
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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
... dinucleotide biosynthesis through tryptophan degradation, an event that implies efficient ACMSD inhibition Therefore, hACMSD would act as a regulatory link between glycolysis and NAD synthesis The ... for nicotinamide nucleotide synthesis in isolated rat liver cells Br J Nutr 59, 279–287 Shin M, Mori Y, Kimura A, Fujita Y, Yoshida K, Sano K & Umezawa C (1996) NAD+ biosynthesis and FEBS Journal ... malaria symptoms by controlling both PA and NAD levels [7,34–36] Recently, a direct link between NAD synthesis and diabetes has been reported [37], suggesting that an increased NAD level is a desirable...
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Tài liệu Báo cáo khoa học: Fatty acid synthesis Role of active site histidines and lysine in Cys-His-His-type b-ketoacyl-acyl carrier protein synthases ppt
... peaks at 12% and 16% buffer D, of which the earliest (low salt) peak was two to three times as large as the other The low salt peak was desalted into buffer C and concentrated to 14.0 mg proteinÆmL)1, ... these various enzymes carry out synthesis of rather complicated molecules such as ring systems [13] and wax components [14] are attractive 696 properties for drug synthesis research The fatty acid ... 6551–6559 Shen B (2003) Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms Curr Opin Chem Biol 7, 285–295 Kunst L & Samuels AL (2003) Biosynthesis and secretion of plant...
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Báo cáo khoa học: Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of b-lactam antibiotics pptx
... observed for synthesis of ampicillin Values of 47 ± mM for KNapp and of 3.6 ± 0.22 for (Vs/Vh)max for the synthesis of ampicillin were obtained from fitting Eqn (8) to the data For synthesis of ... formation of synthesis and hydrolysis products Buffers for experiments in D2O were prepared as follows: solutions of 50 mM KH2PO4 and K2HPO4Æ3H2O were made by dissolving the appropriate amount of salt ... catalyzed synthesis and hydrolysis of b-lactam antibiotics References The kinetic properties of PA are important with respect to the yield that can be obtained in a kinetically controlled synthesis...
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Báo cáo Y học: A b-lysine adenylating enzyme and a b-lysine binding protein involved in poly b-lysine chain assembly in nourseothricin synthesis in Streptomyces noursei pot
... latter containing an internal peptide bond To clarify the mechanism of poly b-lysine synthesis during nourseothricin synthesis we set out to isolate the hypothetical poly b-lysine synthetase or its ... Gould, S.J (1983) The Biosynthesis of the streptolidine moiety in streptothricin F Tetrahedron 39, 3493±3505 10 Sawada, Y., Nakashima, S., Taniyama, H & Inamori, Y (1977) Biosynthesis of streptothricin ... adenylation domains of peptide synthetases This points to nonribosomal mechanisms of streptothricin biosynthesis However, from the data it was not clear which substrate the enzyme would activate: b-lysine...
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West Bengal University of Technology BF-142, Salt Lake City, Kolkata-700064 Structure & Detailed Syllabus of B.Tech in Food Technology ppt
... West Bengal University of Technology BF-142, Salt Lake City, Kolkata-700064 Structure & Detailed Syllabus of B.Tech in Food Technology 2ND YEAR: ... Language Practice Lab 35 Total of 4th Semester 2 28 West Bengal University of Technology BF-142, Salt Lake City, Kolkata-700064 Structure & Detailed Syllabus of B.Tech in Food Technology 3RD YEAR: ... Practical Total of 5th Semester Credit points 4 28 West Bengal University of Technology BF-142, Salt Lake City, Kolkata-700064 Structure & Detailed Syllabus of B.Tech in Food Technology 3RD YEAR:...
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synthesis of single-crystalline hollow b-feooh nanorods via a controlled
... 2266– 2270 Flynn C.M Jr, 1984 Hydrolysis of inorganic iron(III) salts Chem Rev 84, 31–41 Fowler C.E., D Khushalani & S Mann, 2001 Facile synthesis of hollow silica microspheres J Mater Chem 11, 1968– ... nm and width in the range of 20–30 nm In particular, a process mechanism has been revealed for synthesis of single-crystalline b-FeOOH hollow nanorods: (i) formation of b-FeOOH nanorods by aggregation-dehydration ... Adv Technol 15, 89–92 He T., D Chen, X Jiao, Y Xu & Y Gu, 2004 Surfactantassisted solvothermal synthesis of Co3O4 hollow spheres with oriented-aggregation nanostructures and tunable particle...
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Báo cáo khoa học: Bile acids increase hepatitis B virus gene expression and inhibit interferon-a activity pot
... to regulation by bile acids in human hepatoma cells Cholic acid and chenodeoxycholic acid (CDCA) are two major primary bile acids detected in human bile [19– 21] The effects of bile acids on HBV ... (2002) Bile acid regulation of gene expression: roles of nuclear hormone receptors Endocr Rev 23, 443–463 Bile acid metabolism and HBV gene expression 20 Chiang JY (2004) Regulation of bile acid synthesis: ... Bile acid metabolism and HBV gene expression H Y Kim et al the liver, intestine, kidney and adipose tissue via the regulation of the expression and function of genes involved in bile acid synthesis, ...
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Báo cáo khoa học: De novo synthesis, uptake and proteolytic processing of lipocalin-type prostaglandin D synthase, b-trace, in the kidneys pptx
... possibly attenuates the progression of kidney damage In some renal diseases, the increase in the biosynthesis of L-PGDS in the kidney may be a type of adaptation mechanism against kidney 7154 injury ... performed with Nitro Blue tetrazolium chloride ⁄ 5-bromo-4-chloro-3¢-indolylphosphatase p-toluidine salt (BlueMap Kit; Roche Diagnostics) The sections were counterstained with Nuclear Fast Red (ISH...
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Báo cáo khoa học: Synthesis of b-mannosides using the transglycosylation activity of endo-b-mannosidase from Lilium longiflorum pptx
... 323–335 FEBS Journal 272 (2005) 1660–1668 ª 2005 FEBS Synthesis of b-mannosides using endo-b-mannosidase Ito Y & Ohnishi Y (2001) Stereoselective synthesis of b-manno glycosides In Glycoscience: Chemistry ... VI (1974) Synthesis of derivatives of the trisaccharide repeating unit of the O-specific polysaccharide from Salmonella anatum Carbohydr Res 33, C5–C7 Shaban MAE & Jeanloz RW (1976) The synthesis ... 34, 5140–5143 12 Singh S, Scigelova M & Crout DHG (1996) Glycosidasecatalyzed synthesis of oligosaccharides: two-step synthesis of the core trisaccharide of N-linked glycoproteins using the b-N-acetylhexosaminidase...
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Báo cáo khoa học: Kinetic studies on endo-b-galactosidase by a novel colorimetric assay and synthesis of N -acetyllactosamine-repeating oligosaccharide b-glycosides using its transglycosylation activity pptx
... Wong, C.-H (1992) Enzymecatalyzed oligosaccharide synthesis Anal Biochem 20, 215–238 18 Shoda, S., Fujita, M & Kobayashi, S (1998) Glycanase-catalyzed synthesis of non-natural oligosaccharides Trends ... & Usui, T (1995) Enzymic synthesis of lacto-N-triose ll and its positional analogues Glycoconj J 12, 664–671 Murata, T., Tashiro, A., Itoh, T & Usui, T (1997) Enzymic synthesis of 3¢-O- and 6¢-O-N-acetylglucosaminyl-N-acetyllactosaminide ... dialysed against distilled water overnight at °C The enzyme solution was lyophilized and then used for synthesis of oligosaccharides without further purification The crude enzyme preparation catalysed...
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Báo cáo hóa học: " Nanostructured Hypoeutectic Fe-B Alloy Prepared by a Self-propagating High Temperature Synthesis Combining a Rapid Cooling Technique" ppt
... instantaneous release of a large amount of heat that ignites the aluminothermic reaction and the synthesis reaction was subsequently finished in a few seconds The products were kept in the reactor...
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Báo cáo hóa học: "Synthesis, structure and magnetic properties of b-MnO2 nanorods" pptx
... the surface layer in the rich temperature-dependent magnetism of this material Synthesis and characterization The synthesis of the b-MnO2 nanorods involved LiOH, Mn(NO3)2 · H2O and citric acid ... autoclave Hydrothermal synthesis was performed at 100 °C for 48 h The product was filtered and rinsed with ethanol and dried at 100 °C for 12 h The polymer involved in the synthesis was fired out ... hydrothermal synthesis [7], so that this kind of structure of the b-MnO2 nanorods seems to appear quite commonly Conclusions To summarize, we presented a hydrothermal method for the synthesis of...
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Amino acids, peptides and proteins in organic chemistry volume 4 protection reactions, medicinal chemistry, combinatorial synthesis (amino acids, peptides and proteins in organic chemistry (VCH)) andrew b h
... Analysis 340 Synthesis of N-Glycopeptides 342 Synthesis of RNase C Glycoprotein 343 Synthesis of Erythropoietin N-Glycopeptide Fragment 1–28 346 Synthesis of Biantennary Dodecasaccharide 346 Synthesis ... High-Throughput Synthesis of Peptides 396 Parallel Peptide Synthesis 396 Directed Sorting 400 Synthesis of Peptide Arrays 402 Peptide Libraries 406 Synthesis of Peptide Mixtures 406 Synthesis of ... Synthetic Protocols 421 Pin Synthesis 421 SPOT Synthesis 422 Synthesis in Tea-Bags 422 Synthesis on Cotton 423 Modification of the Cotton Carrier 423 Split-and-Mix Synthesis of OBOC Noncleavable...
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2000 thi bang A va B.pdf
... ever-growing proportion of this consists of unburned hydrocarbon gases from the exhausts of automobiles a pollute b polluted c pollution d pollutant > c 241 His wife died in when he was only...
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