by and works inspired by or derived from shakespeare and his works
Tài liệu Báo cáo khoa học: Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites doc
Ngày tải lên :
20/02/2014, 11:20
... future work and the basis for the investigation of the protein-bound, pharmacophore conformation of the ligands The stronger inhibitory potency of MWP-containing peptides [Trp2-Tat(1–9) and TXA2R(1–9)] ... mechanisms of inhibitor–DP IV interactions is important for the development of more potent and more selective DP IV inhibitors as therapeutics in diseases including diabetes and multiple sclerosis ... competitive inhibitors of DP IV with Ki values between 5.02 · 10)6 M and 4.36 · 10)5 M (Table 1) This inhibition type is characterized by the formation of EI and ES complexes resulting from a direct...
- 10
- 505
- 0
Báo cáo khoa học: Oxygen control of nif gene expression in Klebsiella pneumoniae depends on NifL reduction at the cytoplasmic membrane by electrons derived from the reduced quinone pool doc
Ngày tải lên :
17/03/2014, 10:20
... but frd::tet RAS53/pNH3 RAS53/pJES851 [8] [8] [8] This This This This This This cloning vector Topo-TA cloning vector allelic exchange vector, oriR6K; rpsL*(Streps), Ampr, Kanr K pneumoniae nifLA ... system developed by Skorupsky and Taylor [27] The respective genes were cloned by PCRtechniques, a tetracycline-resistance cassette (derived from the MiniTn5 [28]) was inserted and the resulting ... fragment from pRS177 in pKAS46 pRS191, but nuoCD::tet nuoCD::tet fragment from pRS194 in pKAS46 Stratagene Invitrogen [27] [4] [30] [31] This study This study This study This study This study This...
- 12
- 488
- 0
international finance; theory and policy (derived from creative commons licensed edition published by flat world knowledge, ca. 2010), by steven m. suranovic
Ngày tải lên :
05/11/2014, 12:38
... http://www.nber.org/cycles.html Saylor URL: http://www.saylor.org/books Saylor.org 38 Saylor URL: http://www.saylor.org/books Saylor.org 39 1.5 International Macroeconomic Institutions: The IMF and the World Bank LEARNING ... important ways: trade and investment Trade encompasses the export and import of goods and services Investment involves the borrowing and lending of money and the foreign ownership of property and ... supply and demand for currencies in the private marketplace Saylor URL: http://www.saylor.org/books Saylor.org 27 g The term for the measure of the total value of foreign assets held by domestic...
- 465
- 662
- 0
Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf
Ngày tải lên :
08/03/2014, 22:20
... methylanthraniloyl-UDP-Glc (MUG), and binding studies of this fluorophore to TcdA We have also used this fluorophore to probe the interaction of TcdA with Mg2+ and UDP-Glc the presence or absence of TcdA (100 lgÆmL)1) ... obtained from BioRad Crude methylisatoic anhydride, obtained from Aldrich, was recrystallized twice from hot acetone prior to use C difficile toxin A (TcdA) was purchased from Tech Laboratory, Blacksburg, ... prior to formation of any mechanistic intermediates, such as an oxocarbonium ion, that might lie along the reaction coordinate for glucosyltransfer This work was generously supported by the Indiana...
- 8
- 516
- 0
Relative risk of surface water pollution by E. coli derived from faeces of grazing animals compared to slurry application pptx
Ngày tải lên :
15/03/2014, 23:20
... to land from grazing animals and from slurry stores, and relative timing of slurry and fresh faecal inputs to ®elds Time spent by livestock on hard-standing areas and tracks vulnerable to runoff ... gauge recordings were undertaken at this point (22 samples over 34 hours) Total and faecal coliforms, nitrate, ammonium and total organic carbon were determined on these water samples by standard ... pollution by E coli derived from animal faeces and slurry Table Summary of outputs of E coli (c.f.u ha±1) and water in drainage and runoff from plots, assuming 1.4 kg fresh faeces ewe±1 day±1 and 0.7...
- 10
- 445
- 0
Báo cáo Y học: Characterization of heparin binding by a peptide from amyloid P component using capillary electrophoresis, surface plasmon resonance and isothermal titration calorimetry ppt
Ngày tải lên :
31/03/2014, 23:20
... water, and electrophoresis buffer Samples were pressure injected for s after a 2-s preinjection of water and were subjected to electrophoresis from a separate set of buffer vials than those used for ... confirmed by the observation of a 2500 resonance unit (RU) increase in the chip for regular peptide and 3200 RU for the scrambled Sensorgrams for the binding of heparin to immobilized regular and scrambled ... directly for binding while the purified components had to be used in the SPR and ITC approaches Model simulations of the AP-1 peptide structure show that a random coil or b sheet form are more favored...
- 8
- 347
- 0
Báo cáo sinh học: " Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein" doc
Ngày tải lên :
19/06/2014, 08:20
... and dissemination; and potential for high morbidity and mortality and major health impact All of the above reasons illustrate why an effective antiviral therapy is needed for henipaviruses Paramyxoviruses ... of HeV and NiV [25,34] Although both HR-1 and HR-2 derived peptides exhibited fusion inhibitory activity, the HR-2 peptide (residues 447–489) was more potent and more soluble The HeV and NiV ... fusion inhibitors by reducing their length and chemically modifying their amino and carboxyl termini either by amidation or acetylation or through the addition of a PEG10 moiety, and have examined...
- 15
- 387
- 0
báo cáo hóa học:" Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein" doc
Ngày tải lên :
20/06/2014, 04:20
... and dissemination; and potential for high morbidity and mortality and major health impact All of the above reasons illustrate why an effective antiviral therapy is needed for henipaviruses Paramyxoviruses ... of HeV and NiV [25,34] Although both HR-1 and HR-2 derived peptides exhibited fusion inhibitory activity, the HR-2 peptide (residues 447–489) was more potent and more soluble The HeV and NiV ... fusion inhibitors by reducing their length and chemically modifying their amino and carboxyl termini either by amidation or acetylation or through the addition of a PEG10 moiety, and have examined...
- 15
- 266
- 0
Báo cáo sinh học: "Transplanted astrocytes derived from BMP- or CNTF-treated glialrestricted precursors have opposite effects on recovery and allodynia after spinal cord injury" docx
Ngày tải lên :
06/08/2014, 18:21
... astrocytes isolated from the immature cortex [9-12] Factors such as contamination with microglia and undifferentiated progenitors, isolation from cortex rather than spinal cord, and a phenotype that ... as poor support of axon growth and expression of Olig2 and inhibitory CSPGs, supports the hypothesis that they are functionally similar GDAs and suppression of axon-growth-inhibitory scar formation ... displayed immunoreactivity for the axon-growthinhibitory proteoglycan neurocan at and days postinjury (Figure 4b) and the majority of GDAsCNTF had retained their in vitro immunoreactivity for NG2 (Figure...
- 20
- 455
- 0
Báo cáo y học: " Effects on osteoclast and osteoblast activities in cultured mouse calvarial bones by synovial fluids from patients with a loose joint prosthesis and from osteoarthritis patients" pdf
Ngày tải lên :
09/08/2014, 10:20
... leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-κB ligand, osteoprotegerin, and receptor activator of NF-κB in mouse ... and the County Council of Västerbotten and by grants from the Foundation of Sven Norén We thank Ingrid Boström for careful preparation of the figures and Birgit Andertun and Inger Lundgren for ... Lerner UH: New molecules in the tumor necrosis factor ligand and receptor superfamilies with importance for physiological and pathological bone resorption Crit Rev Oral Biol Med 2004, 15:64-81 25...
- 14
- 332
- 0
Báo cáo y học: "Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-B-dependent transcription of TNF-a and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA" ppsx
Ngày tải lên :
11/08/2014, 03:20
... for TLR-3 and TLR-8 are double and single stranded RNA, respectively In these experiments we used the artificial ligands poly(I:C) for TLR-3 and resiquimod (R-848) for TLR-8 HEK293/TLR3 and HEK293/TLR8 ... untreated (A) or treated with LPS (1 μg/ml) for 20 (B) or 60 (C) then stained In panel D, cells were treated with 25 μM TMP for 60 while panels D and F show treatments with LPS and TMP for 20 and 60 ... LPS (A) or 1µg/ml of LPS and 25µM TMP (B) for the indicated times Lysates were prepared and analyzed by western blot with Abs specific for the phosphorylated serine 32 residue of IB-a and total...
- 11
- 622
- 0
Báo cáo y học: " Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular " doc
Ngày tải lên :
12/08/2014, 23:22
... Rockford, IL) and exposed to X-ray films Acknowledgements This work was supported by NIH grant NS044832 to JR We thank Gitanjali Srivastava and Ted Diehl for technical assistance We thank Andrew Byrnes ... triggered by SCF Young and collaborators have shown that alpharetroviral and gammaretroviral vectors carrying unmodified ALV envelope glycoproteins and bearing specific ligand proteins or single ... Env glycoproteins derived from ALV subgroups A and B Furthermore, vectors pre-incubated with bi-functional bridge proteins encoding human erythropoietin (Epo) or stem cell factor (SCF) fused to...
- 15
- 176
- 0
Báo cáo sinh học: "Computing approximate standard errors for genetic parameters derived from random regression models fitted by average information REML" potx
Ngày tải lên :
14/08/2014, 13:22
... records at different ages A VCV matrix for additive genetic and phenotypic effects for weight over a 450-day trajectory was derived based on the analysis performed by Fischer et al [2] Data for this ... function and justification of this concern was demonstrated in this study Moreover, the same method can be applied to other random effects to get standard errors for their respective proportion of ... 365 Standard error of heritability from random regression individuals and the symbol ⊗ denotes direct product The solution for K can be used as in equation (1) to calculate the variances and covariances...
- 8
- 265
- 0
DNA Recognition and Cleavage by Phenyl-Benzimidazole Modified Gly-Gly-His-Derived Metallopeptides
Ngày tải lên :
24/08/2014, 12:58
... Ni(II)·Arg-Gly -His and Ni(II)·Lys-Gly -His (A); Minor groove binding by Ni(II)·Arg-Gly -His with the O2 of thymine and N3 of adenine (B) Furthermore, the average structure of Ni(II)·L-Arg-Gly -His produced from ... degradation by Ni(II)·Gly1-Gly2 -His metallopeptides 24 1.20 Structures of Ni(II)·Arg-Gly -His and Ni(II)·Lys-Gly -His (A); Minor groove binding by Ni(II)·Arg-Gly -His with the O2 of thymine and ... Recognition and Cleavage by Phenyl-Benzimidazole Modified Gly-Gly -His -Derived Metallopeptides Major Professor: Eric C Long Metallopeptides of the general form M(II)·Gly1-Gly2 -His induce DNA strand scission...
- 67
- 172
- 0
principles of macroeconomics (derived from creative commons licensed edition published by flat world knowledge, ca. 2009)
Ngày tải lên :
05/11/2014, 13:01
... In rankings for all three years, economics majors recorded the highest scores Saylor URL: http://www.saylor.org/books Saylor.org 16 Table 1.1 LSAT Scores and Undergraduate Majors Major field LSAT ... majors listed by 2,200 or more students taking the test in 2003 Table 1.1 "LSAT Scores and Undergraduate Majors"gives the scores, as well as the ranking for each of these majors, in 2003 and ... (including such majors as business administration, Saylor URL: http://www.saylor.org/books Saylor.org 20 finance, English, history, psychology, and political science) MBA graduates who had majored in economics...
- 825
- 291
- 0
study the substitution of fossil fuels by rdf produced from municipal solid waste of hanoi m.a thesis waste management and contaminated site treatment
Ngày tải lên :
09/01/2015, 08:53
... before and after drying Water content is calculated by following formula: YYl — 171 WC = ^ - 100% m0 Formula Total solid (TS): It was indirectly calculated from WC by formula 75' = —WC Formula ... population and quickly growing o f living standard as well as consumerism give Vietnam more and more challenges One o f them is the growth o f energy demand in all sectors Prices of electricity and ... over fluff type It is transportable and easier to handle and store If kept under right condition, densified RDF can be stored indefinitely This kind is also suitable for burning on wider range...
- 51
- 469
- 0
life and death metaphors in some short stories by jack london from cognitive perspective = ẩn dụ về sống và chết trong một số truyện ngắn của jack london dưới góc nhìn tri nhận
Ngày tải lên :
02/03/2015, 14:32
... introduced in the work ―Metaphor We Live By by Lakoff & Johnson (1980) From such reviewing, a working definition of metaphor can be obtained for this thesis Moreover, in order to get deeper ... metaphorical concepts can be coherent or consistent Consistent metaphors ―form a single image,‖ while coherent metaphors are ―subcategories of a major category and therefore share a major common ... from two shorts stories such as To build a fire, The God of his fathers also reveal this concept of this metaphor ―When he had recovered his breath and control, he sat up and entertained in his...
- 63
- 746
- 0
Expansion and its realization in the short story “Runaway” by Alice Munro from systemic functional grammar perspective = Bành trướng và sự thể hiện của nó trong truyện ngắn Trốn chạy của Alice Munr
Ngày tải lên :
10/07/2015, 14:23
... clause expands the meaning of another by one of three ways: by elaborating, by extending, or by enhancing it Extension is, therefore, divided into three categories: elaboration, extension and enhancement, ... clause, group/ phrase, word and morpheme To be more specific, a clause consists of groups, a group of words, and a word of morphemes Every word has a function as part of a group and every group has ... characters portrayed in her story gave me a deep impression and inspired me to choose the story for text analysis In light of the above mentioned, I decided to select this story for analysis to explore...
- 86
- 388
- 0