... Environmental Auditing in 1992, the Working Group on Programme Evaluation in 1992, the
Working Group on Privatization in 1993, and the Working Group on the Audit ofInternational Institutions in 2001, ... highest inthe system of standards, contains the founding principles of government
auditing. Specifically it includes the Lima Declaration adopted at the 9
th
INCOSAI in 1977, because the Lima ... the relationship between documents defining the principles of
government auditing and those defining more detailed auditing procedures is unclear. Thus, INTOSAI is now
considering integrating...
... existing on the aesthetic value assigned (as
well as their frequency of use).
2. Determine therole that the restorative capacity
of a place (in terms ofthe ART) may exercise in its
aesthetic ... place themselves on the other
side ofthe aesthetic spectrum and name, in their
opinion, the three ‘‘most unattractive’’ places in
the city. These places were assessed with the same
variables as the ... representativeness
of each ofthe categories established inthe list of
the most attractive and unattractive places in the
city (those inthe first place), from the percentage
of responses in each category.
The...
... Schematic representation ofthe roles ofthe FadD proteins encoded by the DIM + PGL locus inthe biosynthesis of DIMs and related
compounds in Mycobacterium tuberculosis. Theroleofthe activation enzymes ... [16,18].
To examine the involvement of FadD29 inthe bio-
synthesis of DIMs and PGLs, we took advantage of
the existence inthe laboratory of an M. tuberculo-
sis H37Rv recombinant strain, harboring an ... progress in our knowledge ofthe bio-
synthesis of DIMs and PGLs, thein vivo functions of
these FadD proteins in this pathway remain to be
established and ⁄ or completed. For instance, the
involvement...
... comprehensive overview ofthe rise, role
and status of these private product safety standards inthe legal regulation
of integrating markets. Ininternational and regional trade law as in
European and ... increasingly replacing their regulations
with private standards.
This is a book about the interrelationships between law and standards
in the regulation of integrating markets. It deals with the interaction
between ... for a “World (Internal) Law”? Legal Developments in a Changing International
System’ (2002) 9 Ind J Glob Leg S 401, 402 ( In short, international law is inthe process of trans-
forming, at least...
... 60m in depth. The deepest area (70m) is inthe Andaman Sea at the northern tip of
the Straits, while the shallowest is at the One Fathom Bank inthe south.
The current predominantly flows in ... establishment of artificial reefs with the hope of creating a new
breeding ground for marine fishes. A study by Zainuddin and Razak (2000) and recent
evidence on the increase in marine landings on the ... governing the use of wetlands and mining are still
inadequate due to the absence of clear guidelines, standards or benchmarks for sustainable
utilization ofthe resource.
2.4.2 Living Marine...
... appears
stronger in G
2
⁄ M than in G
1
[44]. This contradicts
repression through a complex in G
1
and in vivo foot-
printing results inthe original definition ofthe sites
[10]. Taken together, the sites in ... Dimethyl sulfate footprint-
ing ofthe CDE inthe presence of SV40 large T indi-
cated a loss of protein occupation on this site in vivo
[79].Elevated expression of cyclin A, cyclin B, Cdc25C
and Cdc2 ... functional mapping ofthe cyclin
B1 promoter did not yield the class II CHR as the site
through which Lin-9 exerts its control [94]. In another
report, depletion of Lin-9, Lin-37, Lin-52 or Lin-54 by
RNAi...
... TGF-aD152 (lacking the last
eight amino acids ofthe ICD) compared to the TGF-a
D158 construct lacking only the last two valine resi-
dues, suggesting a role for an internal motif in the
interaction ... identified the
EWV
614
motif in MT5-MMP ICD as comprising an
important sequence for the interaction with the PDZ
proteins: Mint-3, AMPA binding protein and gluta-
mate receptor interacting protein (GRIP). ... lane 4), therefore confirming the interaction of
these two proteins previously observed biochemically
[37] or using a yeast two-hybrid assay [39]. Interestingly,
in the M2H system, the interaction...
... folding ofthe mutant. The lower
intensity may arise from partitioning ofthe protein
into an aggregated state.
The effect of copper binding on the secondary struc-
ture was determined using CD in ... human cystatins.
Further support for the premise that the C-terminus
could be the copper binding domain comes from stud-
ies ofthe P79S mutant, which differs from the copper
binding forms of stefin ... important inthe brain, there-
fore theroleof copper binding or loss of its binding
could be related to specific cerebellar function(s) of
stefin B [18], which remains to be seen by more in vivo
studies.
Stefin...
... demonstrates the important roleof GALA in
the degradation of both linear and
L
-arabinose-substituted
galactan side chains of pectin. This is in agreement with a
previous study in which the synergy of ... under
the control ofthe xylanolytic activator protein [32,41]. The
increase in expression levels of galA inthe CREA mutant,
indicates that at least one ofthe detected putative CREA
binding sites ... synergy of enzymes degrading
the pectin side chains was studied [34]. GALA had a positive
effect on the activity ofthe other enzymes involved in the
degradation of these side chains.
DISCUSSION
A....
... of GSK3 (using Li or SB-415286)
appears to be sufficient for inducing activation of GS in
muscle and fat cells, and that inhibition ofthe kinase
potentiates insulin action in muscle of insulin-resistant ... (1994) The inhibition of glycogen
synthase kinase-3 by insulin or IGF-1 inthe rat skeletal muscle cell
line L6 by wortmannin, but not rapamycin: evidence that wort-
mannin blocks activation ofthe ... phosphatidylinositol
3-kinase, p70, S6 kinase and glycogen synthase kinase-3 activity in
L6 muscle cells: evidence for the involvement ofthe mammalian
target of rapamycin (mTOR) pathway in the
L
-leucine-induced
up-regulation...
... 20 lL ofthe enzyme/inhibitor mixture to 180 lLof
substrate (4NPGlc), incubating for 30 min at 37 °C, and
measuring the rel ease of 4NP.
Protein assays and protein sequencing
Total protein in crude ... rate of 1 mLámin
)1
.The
following gradients were used: incubations containing
arbutin or salicin as substrate; 100% C initial, i ncreasing
D t o 2 0% (10 min), 50% ( 15 min), 100% (5 min), held ... oleuropein (olives). The fourth general property
of enzymes involved in transformation of xenobiotics is
increased enzyme levels inthe presence of xenobiotic
substrates, i.e. inducibility. Cloning the...
... likely
that the increased rate of
13
C label incorporation into the C6
position of glycogen inthe ADM group is indicative of
activated 6-phosphofructo-1-kinase, which can lead to
increased
13
C labeling ... labeling at the triose level. Such a mechanism
can lead to increases in labeling of glycogen C6 even in the
presence of decreased activity ofthe indirect pathway,
provided that the increase in glycolytic ... achieved inthe intact
liver in vivo. The importance ofthe detection of label
incorporation into glycogen C6 while infusing [1-
13
C]glu-
cose can be appreciated from the fact that this labeling
pattern...