brs derivation of nf κb binding potential and determination of direct positive correlation between binding potential and in vivo tf binding
Báo cáo y học: "The functional spectrum of low-frequency coding variation" pot
Ngày tải lên :
09/08/2014, 23:20
... singleton INDELs with a length of 1, in order to remove the high number of false positive INDELs in this category Broad Institute Illumina INDEL calling pipeline Read mapping The BI Illumina INDEL ... Illumina INDEL calling pipeline Read mapping The BCM-HGSC Illumina INDEL calling pipeline used the MOSAIK alignments created at BC as explained in the SNP calling methods Duplicate filtering Duplicate ... sequencing platform, which may make 1- or 3-bp INDELs appear to be bp long When combining call sets from BCM-HGSC and BI, and calculating concordance, INDELs within bp of each other and of the...
- 17
- 291
- 0
Báo cáo khoa học: Supramolecular calsequestrin complex Protein–protein interactions in chronic low-frequency stimulated muscle, postnatal development and ageing pot
Ngày tải lên :
08/03/2014, 10:20
... TRI and the CSQ -binding element JUN, show decreased protein–protein interactions during fiber type shifting and the ageing process Reduced protein coupling between the major elements regulating ... changes in the labeling intensity of the apparent 94 and 560 kDa bands after days of electro-stimulation, and a drastic decrease in the decoration of the 63, 94 and 560 kDa bands after 78 days of ... fast and slow CSQ isoforms exhibit different degrees of self-aggregation and heterogeneous protein–protein interactions Slow CSQ might be involved in a more indirect type of physiological coupling...
- 10
- 342
- 0
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
Ngày tải lên :
31/10/2012, 17:03
... levels in men and we show in this work that similar associations are operating in women, we also looked for a potential gene-to-gene interaction between PPARδ and apoE Allelic variation in apoE ... triglycerides, and insulin [5] In addition, transgenic expression of an activated PPARδ in mice conferred resistance to obesity and hyperlipidaemia [6] Considering that the C allele is linked to a higher ... numerous interacting genes are altered which may influence the effect of PPARδ on metabolism In our data and in the study by Skogsberg et al., the effect of the C allele on lipid levels increased if...
- 4
- 568
- 0
iec 60439-1 low-voltage switchgear and controlgear assemblies - type-tested and partially ty
Ngày tải lên :
25/12/2013, 11:00
... personal injury, property damage or other damage of any nature whatsoever, whether direct or indirect, or for costs (including legal fees) and expenses arising out of the publication, use of, or ... carrying out certain operations and maintenance work 2.4.9 cover plate a part of an ASSEMBLY in general of a box (see 2.3.3.4) which is used for closing an opening in the external enclosure and ... surface of an insulating material between two conductive parts [2.5.51 of IEC 60947-1] [IEV 471-01-08 modified] NOTE A joint between two pieces of insulating material is considered part of the...
- 212
- 889
- 10
iec 60439-2 low-voltage switchgear and controlgear assemblies - particular requirements for busba
Ngày tải lên :
25/12/2013, 11:05
... field in the vicinity of busbar trunking system 49 Annex J (informative) Annex L (informative) Verification of maintenance circuit integrity under fire conditions 51 Annex M (informative) ... amendment and the following documents: FDIS Report on voting 17D/225/FDIS 17D1228/RVD Full information on the voting for the approval of this standard can be found in the report on voting indicated in ... thermocouples located in the centre of each busbar trunking unit and adjacent joints and shall comply with the values of IEC 60439-1, table 3, including note of this standard COPYRIGHT International...
- 74
- 821
- 14
iec 60439-3 low-voltage switchgear and controlgear assemblies - particular requirements for iow-v
Ngày tải lên :
25/12/2013, 11:06
... the note and Table I by the following: For the purpose of this standard the number of main circuits is the number of outgoing circuits connected to each supply phase In the absence of information ... no sustained glowing, or if flames or glowing of the specimen extinguish within 30 s after removal of the glowwire There shall be no burning of the tissue paper or scorching of the pinewood board ... Resistance to rusting and to humidity 8.2.1 Verification of resistance to rusting and to humidity 1* 3* 8.2.14 k) Resistance of insulating materials to heat 8.2.1 i) Resistance of insulating materials...
- 49
- 488
- 4
iec 60439-4 low-voltage switchgear and controlgear assemblies - particular requirements for assem
Ngày tải lên :
25/12/2013, 11:07
... ACS Example: an incoming supply and metering ASSEMBLY and a main distribution ASS EMBLY The definitions of the various types of ACS are given in 2.1 and 2.12 Within the limits indicated below, ... ground compatible with the radius of curvature of the largest cable that may be connected to the ACS 7.2.5 Lifting and handling devices of ACS Lifting rings and/ or handles (or any other equivalent ... connected between the main earthing terminals of the ACS and the earthing terminals of the socket-outlets 7.4.3.1.7 Add paragraph c): c) The cross-sectional area of every protective conductor within...
- 56
- 514
- 5
iec 60439-5 low-voltage switchgear and controlgear assemblies - particular requirements for assem
Ngày tải lên :
25/12/2013, 11:08
... Paints and varnishes - Determination of resistance to humid atmospheres containing sulphur dioxide I S 4628-3:1982, Paints and varnishes - Evaluation of degradation of paint coatings Designation of ... 7.4.5 Operating and maintenance gangways within ASSEMBLIES (see 2.7.1 and 2.7.2) Not applicable 7.6 Switching devices and components installed in ASSEMBLIES Selection of switching devices and components ... become unhinged and the operation of the door(s), hinges and locking points are not impaired by the application of a load of 50 N In addition, by verification that the degree of protection remains...
- 56
- 783
- 6
LOW FREQUENCY IGBT CONVERTER FOR CONTROL EXCITING FORCE OF ELECTROMAGNETIC VIBRATORY CONVEYORS
Ngày tải lên :
03/01/2014, 19:15
... converters for obtaining sinusoidal current in the EVA As in the case of SCR can talk about on unidirectional and bidirectional converter type, depending on whether there was DC pulsating or EVA coil ... output In this case switches Q1 and Q2 are in the state “OFF”, while the EVA coil current takes freewheeling diode D1 and D2 Accordingly it is obtained a linear decrease of EVA coil current, since ... represents state vector containing positions and angles of respective parts, and M, C, and K are symmetric matrices Vector Γ defines acting of force f onto the corresponding parts [4-6], [10], [15]...
- 5
- 322
- 0
Tài liệu Social networking sites and our lives doc
Ngày tải lên :
18/02/2014, 00:20
... points What explains this trend? As with our finding that there has been a short-term increase in trust, caution should be taken in interpreting these findings Measures of trust, neighboring and ... points In addition to sampling error, question wording and practical difficulties in conducting telephone surveys may introduce some error or bias into the findings of opinion polls A combination ... LinkedIn and MySpace Some 52% of Facebook users and 33% of Twitter users engage with the platform daily, while only 7% of MySpace users and 6% of LinkedIn users the same By comparison, 62% of...
- 85
- 293
- 0
Tài liệu Báo cáo Y học: Interaction of decorin with CNBr peptides from collagens I and II Evidence for multiple binding sites and essential lysyl residues in collagen pot
Ngày tải lên :
21/02/2014, 15:20
... the in uence on decorin binding of chemical modification of Lys and Hyl side chains of collagens and peptides Derivatizations that eliminate the positive charge of Lys/Hyl eliminate the binding ... acetylation eliminates their binding to decorin Lys/Hyl side chains are therefore present at, or very near to the binding site(s) and their positive charge is a stringent requisite for the binding This ... Keene et al [19] is able, in the presence of minute amounts of proper cations, to interact with GHH in a2(I) and direct the binding of decorin to the collagen C-terminus in CB6 However, this cannot...
- 10
- 575
- 0
Google Sites and Chrome For Dummies pptx
Ngày tải lên :
06/03/2014, 11:20
... whole host of new Web services, including wikis, online apps, and social networking, which are changing how we interact with people and information This new thinking and set of new tools and services ... Using the Google Docs Home 225 Creating, saving, naming, and renaming files 225 Searching for files 226 Viewing, sorting, hiding, and trashing files 227 Uploading and ... Converting, Saving, and Adjusting Doc Options 262 Downloading and converting Google Docs into other types of files 262 Saving new copies, reviewing revisions, and deleting 263 Print...
- 460
- 917
- 0
Providing and Funding Financial Literacy Programs for Low- Income Adults and Youth pot
Ngày tải lên :
06/03/2014, 19:20
... cover making spending choices, “envelope budgeting,”* planning one’s spending, understanding credit and handling credit problems, consumer skills, taking consumer action, and checks and checking accounts ... including preparing youth for and succeeding in employment, and offering other services intended to develop the potential of youth as citizens and leaders Eligible youth are those 14-21 years of ... consulting, technical assistance and training firm for public and private sector leaders nationwide We specialize in helping leaders plan and implement financing and sustainability strategies for initiatives...
- 16
- 504
- 0
Google Sites and Chrome For Dummies potx
Ngày tải lên :
06/03/2014, 23:20
... whole host of new Web services, including wikis, online apps, and social networking, which are changing how we interact with people and information This new thinking and set of new tools and services ... Using the Google Docs Home 225 Creating, saving, naming, and renaming files 225 Searching for files 226 Viewing, sorting, hiding, and trashing files 227 Uploading and ... Converting, Saving, and Adjusting Doc Options 262 Downloading and converting Google Docs into other types of files 262 Saving new copies, reviewing revisions, and deleting 263 Print...
- 460
- 5.9K
- 1
Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx
Ngày tải lên :
07/03/2014, 00:20
... (1995) Insulin-like growth factors and their binding proteins: biological actions Endocr Rev 16, 3–34 Firth SM & Baxter RC (2002) Cellular actions of the insulin growth factor binding proteins Endocr ... effects on insulin-like growth factor binding protein-1, cell proliferation and prolactin secretion Regul Pept 48, 165–177 39 Bunn CR & Fowlkes JR (2003) Insulin-like growth factor binding protein proteolysis ... (2001) Insulin-like growth factor -binding protein stimulates human trophoblast migration by signaling through alpha beta integrin via mitogen-activated protein kinase pathway J Clin Endocrinol...
- 14
- 469
- 0
Báo cáo khoa học: Biochemical characterization of USP7 reveals post-translational modification sites and structural requirements for substrate processing and subcellular localization pptx
Ngày tải lên :
07/03/2014, 05:20
... of USP7 A C223 Protease Core TRAF H464 D481 208 C-Terminal 560 1102 Ubiquitin binding ICP-0 binding EBNA1 / p53 / HDM-2 binding Ataxin binding B 208 560 1102 USP7-FL USP7 1-560 USP7 208-560 USP7 ... Fusion proteins containing the N-terminal domain of USP7 (amino acids 1–205) and variants with deletions of the first 20, 50 and 70 amino acids linked to enhanced green fluorescent protein (EGFP) ... whether conformational changes driven by ubiquitin binding to the core domain, or direct interactions of this region with the substrate would be required for proper recognition and processing In order...
- 15
- 592
- 0
LOW INTEREST RATES AND HIGH ASSET PRICES: AN INTERPRETATION IN TERMS OF CHANGING POPULAR MODELS doc
Ngày tải lên :
17/03/2014, 08:20
... example of the kind of thinking appears in a recent Wall Street Journal article: “Lenders have been doling out increasingly large sums of money and accepting increasingly crummy conditions and meager ... of interest rates (both nominal and real) and the level of asset prices in the world Next, I will consider some aspects of the public’s understanding of the economy, including common understandings ... reinforced 22 by their perception of an era of low nominal rates, and may help reinforce errors in pricing Behavioral economics has always had to confront a public’s partial understanding of...
- 33
- 332
- 0
Báo cáo Y học: SMAP-29 has two LPS-binding sites and a central hinge docx
Ngày tải lên :
17/03/2014, 23:20
... cooperativity in LPS -binding is primarily intramolecular, whereas binding of one LPS -binding site in a SMAP-29 molecule facilitates binding by the other site The Hill coefficient of the mixture ... simulated annealing and geometry optimization studies for each conformer-set of coordinates using INSIGHT software RESULTS Calculation of structures and molecular modeling LPS Binding Peak volumes ... apparent In earlier studies that examined binding of LL-37 to LPS, we obtained EC50 values of 0.36 lM for LL-37, along with evidence for positive cooperativity [11] The LPS binding domains of LL-37...
- 9
- 412
- 0
Environmental Health Criteria 238 EXTREMELY LOW FREQUENCY FIELDS docx
Ngày tải lên :
22/03/2014, 16:21
... circulating levels of specific hormones of the neuroendocrine system, including melatonin, released by the pineal gland, and to a number of hormones involved in the control of body metabolism and ... irrespective of their state of motion A single charge at a point produces an electric field in all directions in a pattern with spherical symmetry and infinite dimension A line of charges (e.g a power line) ... relative contributions of internal and external sources, the influence of wiring/grounding practices and other characteristics of the home could give insights into identifying a relevant exposure...
- 544
- 243
- 0
High-Impact, Low-Frequency Event Risk to the North American Bulk Power System ppt
Ngày tải lên :
30/03/2014, 09:20
... clearer and more direct lines of communication and coordination with the electric sector Focus should be given to improving the timely dissemination of information concerning impending threats and ... including a contingency/reserve margin to meet balancing and regulating needs Each Balancing Area can maintain reliability even with the loss of more than the single largest generating unit in ... dissemination of information concerning impending threats and specific vulnerabilities, and on the provision of information with sufficient engineering depth for privatesector entities to evaluate and...
- 120
- 517
- 0