... understand the basic processes that have been disrupted, resulting in the vascular malformation Between observational and genetic studies in humans and biochemical and cellular studies at the bench ... further understand thehuman phenotype Recent investigations have further refined our understanding of this phenotype, and bear reviewing in this manuscript In human CCM disease, the lesions exhibit ... from neuronal cells to the endothelium, with a primary defect in the neuronal cell Alternatively, the defect may lie primarily in endothelial cells, andthe CNS selectivity of the disease could be...
... of the Molecular Biology of Brain Tumors andthe Therapeutic Implications high grade gliomas The structure and compounds of the ECM of thebrain tissue have many specific differences from other ... treat primary and metastatic brain tumors, the incidence and mortality rates of these tumors is increasing Particularly affected are young adults andthe elderly The present standard treatment ... enviro‐ ment and form it similar to the tumor tissue The process of the peritumoral invasion de‐ pends on the confrontation zone of the tumor cells andthe non-neoplastic cells and ECM Glioma...
... 1) The predominant band represents the cytosolic variant A gambiae TrxR-1, andthe 62 kDa band is possibly the mitochondrial precursor variant This assumption is supported by the size of the ... delineate the pathways of electrons in A gambiae TrxR-1 during catalysis (Figs and 4) The reducing equivalents flow from the nicotinamide of NADPH via the flavin andthe pair Cys57/Cys62 to the redox ... The characterization of A gambiae TrxR allows the comparison of three different mechanisms of Trx reduction in the P falciparum malaria system, i.e that in the parasite, thehuman host, and the...
... to humankind— everything belongs to Him As the Psalmist says: ‘ The earth is the Lord’s andthe fullness thereof, the world and those who dwell therein, for he has founded it upon the seas and ... upon the rivers’’ (Ps 24:1, New Revised Standard Version translation) Furthermore, from the beginning, humankind was commanded to ‘‘be fruitful and multiply and fill the earth and subdue it and ... world The way humans understand their role(s) in the world underwrites the impetus for technological expansion—it reveals their understanding of the teleology of technology Especially in the American...
... he both afrms and denies at the same time But perhaps they not signify the same thing (for neither did the names in the former case) As a result, what is the difference? And if in the one case ... in the second half of S.E In S.E 16, Aristotle introduces his second concern: the problem of false reasoning from the standpoint of the potential victim of the sophism rather than from the standpoint ... chapter 1) and, on the other hand, other kinds of multiple signication that he divides among the three fallacy types The ways he differentiates among homonymy, amphiboly, and Form of the Expression...
... of the sun, and laws about the rectilinear propagation of light, and one can also derive the height of the flagpole from the length of the shadow, the elevation of the sun, and laws about the ... attitude: The scientific believe that our minds the behavior of our brains—can be explained by the interactions of nerve cells (and other cells) andthe molecules associated with them (1994: 7) Neither ... to mimic the extracellular fluid environment of the synapse in vivo They delivered current to the nerve and recorded a change in the electrical potential of the muscle Then they varied the Ca2+...
... neuronal excitability and pharmacological responsiveness after TBI These studies, therefore, support the hypotheses that TBI alters the constituent proteins of the GABAAR and that these alterations ... dura and sealed with cyanoacrylate adhesive Dental acrylic was applied over the entire device to secure the hub to the skull (leaving the hub accessible) The incision was sutured and betadine and ... most of the GABAAR found in the hippocampus, and were chosen based on their relative abundance and their potentially important contributions in GABAAR function When the expression of these proteins...
... that the functions of the animals and their role in the ordered system are addressed at the end of Genesis 1:26 When humans subdue and rule, they are identifying functions for the animals and ... calling and passion for the original languages andthe opportunity to study, research and write, use their expertise for the benefit of those who not In the same way, those who have the gifts, ... importantly than the six occurrences of the verb in Genesis 1, the verb is used in Exodus 20:11: “In six days the Lord made [ʿāśâ] the heavens andthe earth, the sea, and all that is in them.” This...
... motivate them andthe means they employ in order to satisfy them, depend in fact very closely on their position in the field, i.e on their scientific capital andthe power it gives them over the field ... is thecondition of its and this amounts to the same thing the question of functioning, or, the field’s degree of autonomy (in relation, first, to the social demands of the dominant class andthe ... debate between the principle giving primacy to observation and experimentation, and hence to the corresponding dispositions and capa- cities, andthe principle which privileges theory andthe correlative...
... then the trigram wi−2 wi−1 wi is a feature, as is the bigram wi−1 wi andthe unigram wi In this case, the weight on the transition wi leaving state h must be the sum of the trigram, bigram and ... ), the current best-scoring hypothesis zi is found, and if it differs from the reference yi , then the cost of each feature2 is increased by the count of that feature in zi and decreased by the ... parameter has on the error rate, and then modifies the parameters to reduce the error rate based on this prediction Linear Models, the Perceptron Algorithm, and Conditional Random Fields This...
... about their basic properties I explore two fascinatingly rich and detailed areas of inquiry: animal communication and cognition on the one hand andhuman natural language on the other Although they ... separate issue from whether or not they have the capacity to learn and use a language in the specific sense that refers to human languages By using the expression ‘ humanlanguage ’ repeatedly, ... always to the here and now the attitude or the internal state of the animal doing the signaling Even rather rich systems devised and used by humans share this limitation, to the degree that they are...
... laughter and amusement, as of our grief, pain, anxiety and tears, is none other than thebrain It is specially the organ which enables us to think, see and hear, and to distinguish the ugly andthe ... beautiful, the bad andthe good, pleasant and unpleasant It is thebrain too which is the seat of madness and delirium, of the fears and frights which assail us” (Taken from Chadwick and Mann’s ... due to the lack of interest or research on thebrain but rather due to the complexity of its structure at the macroscopic, microscopic and molecular levels Thebrain provides clinicians and scientists...
... with humanbrain tissues Sera of patients andthe strong cross-reactivity peptides showed a similar pattern on the staining of neuron of thehumanbrain tissues (Fig and 3) These suggested the ... H: Human immunodeficiency virus type infection increases the in vivo capacity of peripheral monocytes to cross the blood -brain barrier into thebrainandthe in vivo sensitivity of the blood -brain ... LWB and ZLF designed the experiment and edited the manuscript QC provided overall supervision, financial support and prepared the final version of the manuscript All authors read and approved the...
... tympanic thermometer; Sherwood Medical, 's-Hertogenbosch, the Netherlands) and EEG activity (Nicolet One system, Viasys Healthcare, Houten, The Netherlands), from about two hours before the administration ... alertness alpha and beta activity changes in the relative band power and absolute band power of the occipital and central electrodes (P4O2, P3O1 and F4C4, F3C3, respectively) were used, and also changes ... performed the EEG analysis SvdW performed the CFT analysis MV performed the BSP blood analysis PP, LS and CH supervised the conduct of the study and writing of the paper JvdH corrected the manuscript...
... in the ERPs 11 Literature Review 1.2 PROPERTIES OF THE VISUAL SYSTEM IN PRIMATE ANDHUMANBRAIN Understanding the visual system‘s structure and function is vital to understanding how, when and ... Ungerleider, 1993) The two-stream hypothesis is supported by evidence from mice brains showing two sub-networks – one connected to the parietal and motor cortices, and another to the temporal andthe parahippocampal ... with regards to the organisation of the visual system (Figure 1.4) and to a distinction between the so called fast and slow brain areas within it The areas that belong to the fast brain include...
... among persons infected with thehuman immunodeficiency virus Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated ... women in Korea J Parasitol 2008; 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163 ... 134 aged This is particularly true with regards to T gondii, where the consequences of infection can be very severe, while the risk of living with one’s beloved cat is practically nill References...
... between the inlet and outlet vapor pressures in the channel The difference between the inlet andthe outlet water vapor pressure is here due to the flux in the x-direction (mainly related to the ... geometry Therefore, the critical operating current presented here refers of course to the modeled fuel cell and is not necessarily the same for other fuel cells However, the method andthe tendencies ... produced at the cathode side The water flowing in the membrane is absorbed on one side and desorbed on the other The following transport phenomena are taken into account First, the motion of the gas...
... resource portals on the management of the protean career The chapter is divided into five sections The first section discusses the reasons leading to the emergence of the protean career The second section ... skills and expertise that are in high demand, they tend to define the terms of their employment For them, career success is defined in terms of knowledge acquisition and personal challenges, rather ... in order to learn about themselves and express their individual values (Sellers, 1994) Fourth, the advance of information technology and particularly the Internet andthe World Wide Web has dramatically...
... These results are in keeping with the view (see next section) that there was a hiatus in southern Iberia between the extinction of the Neanderthals andthe arrival of the first modern humans The ... even though they lived close by in the hills and mountains of Crimea, the Caucasus andthe Altai (Soffer, 1994) Similarly, when cold and arid conditions took hold the range of the Neanderthals ... interpreted these results as follows: conditions in southern Iberia during the Acheulian and Mousterian andthe methods that humans used for exploiting the landscape were such that, at the scale...
... picture therefore, we have on the one hand the identity of the thinking subject, and on the other hand the multiplicity of the representations which it has The same complex thinking subject – as the ... make There are two ways, Kant suggested, that we can look at judgments: on the one hand, we can regard the form of the judgment (how the subject is related to the predicate); and, on the other hand, ... correlated therefore to the “synthetic” unity of the multiplicity of experience On the basis of this, Kant drew his most basic conclusion: a condition of both the synthetic unity of the multiplicity...