bmi1 s role in stem cells and development
Tài liệu LIVESTOCK''''S ROLE IN CLIMATE CHANGE AND AIR POLLUTION ppt
... areas, but also into previous pastureland or subsistence cropping, may increase CO2 emission In addition, practices such as soil liming contribute to emissions Soil liming is a common practice in ... flooding of lowlying areas and other damage Climatic zones could shift poleward and uphill, disrupting forests, deserts, rangelands and other unmanaged ecosystems As a result, many ecosystems will ... change in the carbon and nutrient stocks and cycling of the system This seems to result in a small reduction in aboveground C stocks and a slight decline in C fixation Despite the small, sometimes...
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South Africa''''s role in conflict resolution and peacemaking in Africa docx
... understanding present relations, he also suggests, is South Africa s strategic interest in the massive Lesotho Highlands Water Project (LHWP) for the sale of water from Lesotho s highlands to ... leadership role in defence of human rights and democracy in cases like Zimbabwe and Swaziland, it is simultaneously condemned as insensitive for taking strong and principled actions in the case of Lesotho ... apartheid s hegemonic structures and attitudes were neither erased nor fundamentally transformed, and still find expression in some of South Africa s business and civil society organisations operating...
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Play and it’s role in the mental development of the child
... sister She never behaves with respect to the other Just because she is her sister – except perhaps in those cases when her mother says, “Give in to her.” In the game of sisters playing at “sisters,” ... is, in fact, true The vital difference in play, as Sully describes it, is that the child in playing tries to be a sister In life the child behaves without thinking that she is her sister s sister ... In speaking of play and its role in the preschooler s development, we are concerned with two fundamental questions: first, how play itself arises in development – its origin and genesis; second,...
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Báo cáo y học: "Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation" pdf
... sources of exogenous pluripotent SCs for airway tissue engineering, such as ESCs and MSCs ESCs possess a great pluripotency since they are able to generate a variety of cell lineages including ... human induced pluripotent stem (iPS) cells were shown to utilize signaling mechanisms that are similar to those used by human ESCs [39] The iPS cells present a key advantage over true ESCs since ... clinical applications against acute respiratory distress syndrome [72], asthma [73], and bronchopulmonary dysplasia [74] At present, the therapeutic potential of SCs is intensively assessed in...
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Role of sonic hedgehog signalling in human embryonic stem cells and its neural derivatives
... focus of this thesis 2.2 2.2.1 SHH processing, pathway components and signal transduction SHH processing The Shh protein is synthesized as an approximately 45 kDa precursor which is then processed ... envisioned source of cells for use in cell replacement therapy In particular, medical conditions arising from the loss of neurons, like Parkinson s disease, Alzheimer s disease, stroke and spinal ... diabetes and neurons to treat nervous system disorders (Hyslop et al., 2005b) One nervous system disorder, Parkinson s disease, is a neurodegenerative movement disorder that affects individuals above...
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Societal Burden of Child Maltreatment and Public Health’s Role in Prevention docx
... preventive initiatives to support all families and children 22 Addressing Child Maltreatment in the United States Ideal System Involvement in foster care and court system Services for families and children ... Forensic and specialized interviews Family psychosocial assessments and psychological evaluations Child maltreatment training for family members and professionals Supplement the investigational ... care settings All families in a specific setting Parenting skills training Families at risk Intensive counseling http://www.triplep-america.com 29 Families in crisis Prevention Works! Triple...
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Tế bào gốc và ứng dụng trong y sinh học (Stem cells and the application in biomedicine) potx
... Thomson, J A., et al (1998); Embryonic stem cells lines derived from human blastocysts Science 282, 1145 - 1147 12 Raisman, G., (2001); Olfactory ensheathing cells - another miracle cure for spinal ... 10 Shamblott, M J., et al (2001); Human embryonic germ cells derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro Proc Nat Acad Sci U S A ... circulating human embryonic blood stem cells Blood 96, 1740 - 1747 IItskovitz - Eldor, J and et al (2000).; Differentiation of human embryonic stem cells into embryoid bodies comprising the three...
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Báo cáo y học: "Hypoxic conditions increase hypoxia-inducible transcription factor 2α and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients" pps
... temperature in streptavidin–peroxidase complex (1:500 in DPBS; Dako), rinsed in distilled water and incubated in fast-DAB (3,3'-diaminobenzidine) peroxidase substrate (Sigma) for minutes and counterstained ... mesenchymal stem cells) , and for CD29 (β1 integrin) The cells stained poorly for LNGFR and STRO-1 (markers on freshly isolated bone marrow stem cells) and sparsely for 3G5 (marker for vascular pericytes) ... by SOX5 and SOX6 In the chondrogenic cultures of IPFP cells there was an increase in the expression of SOX9, which was already expressed at a significant level and this was increased more strongly...
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báo cáo khoa học: "Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by lipoic acid: role in cancer prevention and therapy" ppt
... tumor-suppressive effect of LA corresponds with apoptosis induction, a critical parameter impaired in cancer cells, and this induction is selectively exerted in cancer and transformed cell lines, ... experiments using antioxidant response element (ARE) reporter assays, LA has also been shown to induce phase II protective genes which are involved in the prevention of carcinogenesis, in non-cancerous ... culture and growth inhibition assay Human HL-60 cells were obtained from American Tissue Culture Collection (Manassas, VA) and maintained in RPMI 1640 supplemented with penicillin, streptomycin and...
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Báo cáo y học: "The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles" pot
... Statistics Statistical analyses were performed using SPSS software (Statistical Package for the Social Sciences, version 11.5) All results are expressed as means ± standard error of the mean (SEM) ... phosphate buffered saline (PBS) and processed into paraffin Five micron sections were cut, dewaxed and stained with Haematoxylin and Eosin (H&E) for general analysis [5] Mast Cell Staining Mast ... mast cells are involved in IR injury of other skeletal muscle fibre types In this study we selected skeletal muscles, representative of slow-twitch (soleus), slow/fasttwitch (gastrocnemius) and...
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Báo cáo khoa học:" A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages" docx
... identities, and code was not broken until the analysis was completed Statistical analysis Statistics were done by Student 's t test or Fisher 's exact test using Instat (GraphPad, San Diego, CA) Results ... DCs and RS cells were infected with 10 or PFU per cell of McKrae and the virus yield determined at the indicated times by standard plaque assays as described in Materials and Methods Panel B Cells ... amount of infectious virus associated with the RS cells (Fig 1B) This suggests that the low virus titer in DCs was probably not the result of poor virus attachment to DCs as compared to RS cells Replication...
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Báo cáo khoa học: " A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages" pps
... identities, and code was not broken until the analysis was completed Statistical analysis Statistics were done by Student 's t test or Fisher 's exact test using Instat (GraphPad, San Diego, CA) Results ... DCs and RS cells were infected with 10 or PFU per cell of McKrae and the virus yield determined at the indicated times by standard plaque assays as described in Materials and Methods Panel B Cells ... amount of infectious virus associated with the RS cells (Fig 1B) This suggests that the low virus titer in DCs was probably not the result of poor virus attachment to DCs as compared to RS cells Replication...
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Báo cáo y học: "New role for Agrin in T cells and its potential importance in immune system regulation" ppsx
... presynaptic and postsynaptic specializations in the brain, indicating that Agrin has a role, at least in part, in maintaining synaptic structure in this tissue [23] In addition, Agrin is expressed at ... Biotechnology Information Species ISG15-Agrin linkage Chromosome Homo sapiens Yes Pan troglodytes Yes Macaca mulatta Yes Bos Taurus Yes 16 Canis lupus familiaris Yes Mus musculus Yes Rattus norvegicus Yes ... Agrin expression in T cells by sampling a cohort of lupus patients with active and inactive disease in a longitudinal study should provide interesting results, and development of reagents such...
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Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"
... expressed in injured tissues play important roles (2) Stem cells circulate among tissues, and stem cells migrate to the injured tissues once injury occurs Stem cell homing is a complicated process ... osteogenesis and adipogenesis of MSCs (×100) A: One week after osteogenesis induction, alkaline phosphatase staining showed positive cells B: One week after adipogenesis induction, oil red O staining ... After osteogenesis induction for week, alkaline phosphatase staining showed positive cells, and weeks after osteogenesis induction, bone nodule was present demonstrated by VonKossa staining (Figure...
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Tài liệu Georgia Oral Health Prevention Program The School Nurse’s Role in Oral Health pdf
... assessment role Bright Futures: Ensure tooth brushing., teach flossing; Ask about dental sealants Sealants for the second permanent molars Bright Futures: Ensure tooth brushing., flossing; Ask ... Futures: Teach child to brush teeth Discuss flossing Bright Futures: Limit candy, chips, soft drinks Bright Futures: Be sure child brushes teeth Discuss flossing FLUORIDE INFORMATION Review and ... Resource Center responds to the needs of states and communities in addressing current and emerging public oral health issues The resource center supports and stimulates health professionals,...
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Tài liệu The UN’s Role in Nation-Building - From the Congo to Iraq pptx
... Nations—Military policy—Case studies United Nations— Economic assistance—Case studies United Nations—Technical assistance—Case studies Peace-building—Case studies I Dobbins, James, 1942– JZ4984.5.U534 ... Nations restricted its military interventions to interpositional peacekeeping, policing ceasefires, and patrolling disengagement zones in circumstances where all parties invited its presence and ... after the successful conclusion of a first democratic election COPING WITH FAILED STATES During the early 199 0s, the United Nations enjoyed a series of successes This winning streak and a consequent...
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Tài liệu Báo cáo khoa học: A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion docx
... OccWT-overexpressing cells; DE9, OccDE9-overexpressing cells; *P < 0.05 Fig Phosphorylation of ERK1 ⁄ in OccWT-overexpressing cells Immunoblot analyses using specific antibodies against occludin, ERK1 ... determined whether occludin expression in cancer cells was responsible for invasion The Matrigel invasion assay revealed that significantly fewer OccWT-overexpressing Chang and Huh7 cells were invasive ... stage and metastatic potential [9] Furthermore, the overexpression of TJ proteins such as claudin-1 and claudin-4 induces apoptosis and suppresses metastatic potencies [10,11] Occludin has also...
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Tài liệu Báo cáo khoa học: Bone morphogenetic protein signaling in stem cells ) one signal, many consequences pptx
... analyses of these experiments reveal that BMP4 not only suppresses expression of prosensory markers (itself including), but also drives the proliferative sensory precursor cells into apoptosis In ... expression of BMP4 in explanted chicken otic vesicles leads to fewer hair cells [38] Inhibition of BMP signals by Noggin results in increasing numbers of hair -cells Cell-cycle and apoptosis analyses ... BMP signaling in stem cells version, the type II receptors then phosphorylate the type I receptors, which subsequently activate R-Smads (Smads 1, and for BMP ligands) by serine-threonine phosphorylation...
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Tài liệu PHD AND MASTER’S STUDIES IN ECONOMIC, ACCOUNTING AND BUSINESS HISTORY. pdf
... http://www.victoria.ac.nz/fgr/prospective‐phds and http://www.victoria.ac.nz/fgr/masters The Economic, Accounting and Business history Network also runs a seminar series, produces working papers and has links to a number of research institutions around the world. For more information ... http://www.victoria.ac.nz/fgr/prospective‐phds/qualifications‐required.aspx In addition to formal qualifications and competence in English, various qualities will help ensure success: • A strong interest in a substantial research project ... A strong interest in a substantial research project • Self‐discipline • Persistence in the face of setbacks • Willingness to respond effectively to advise and criticism • Ability to work independently • Willingness to work within the scholarly tradition ...
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Đề tài " On De Giorgi’s conjecture in dimensions 4 and 5 " pdf
... illustrate the strength as well as the limitation of this approach As we shall see below, the passage from lower estimates on balls to upper estimates on cylinders is simpler in this case Proposition ... dimension in [2], yet the approach in this paper seems to be the first to use, in an essential way, the solution of the Bernstein problem stating that minimal graphs in Euclidean space are necessarily ... hypersurfaces that it is sometimes referred to as “the version of Bernstein s problem for minimal graphs” The conjecture has been completely settled in dimension by the authors [15] and in dimension...
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