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Báo cáo Y học: Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the a or b catalytic subunit potx
... phosphatase activity toward the two peptide substrates by the CaN autoinhibitory peptide, and the FKBP12/FK506 complex The activation of CaN phosphatase activity towards pNPP by the FKBP12/FK506 ... characterized by different Km and Vmax values toward the same substrate For each substrate tested, CaN heterodimers containing the CnAa catalytic subunit are characterized by lower Km and higher ... due to insufficient CaN phosphatase activity [6] Our findings that the CnAa and CnAb catalytic subunits confer differences in substrate affinity and phosphatase activity (as shown by Table Summary...
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Susceptibility of annealed starches to hydrolysis by α amylase and glucoamylase
... was found to be most susceptible to glucoamylase, followed by an intermediate group of barley, maize, and tapioca starch, and then the least susceptible group of potato, amylomaize-7 and shoti ... sealed and allowed to stand for h prior to analysis The sample was scanned from 25 °C to 130 °C at a rate of 10 °C/min The onset (To) , peak (Tp) and conclusion (Tc) gelatinization temperature and ... the initial stage and then reached a plateau of $16% conversion Kimura and Robyt (1995) and Yook and Robyt (2002) reported a similar trend with native starches by glucoamylase and a-amylase, respectively...
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Báo cáo y học: "Response to commentary by Dixon and Silman on the systematic review and meta-analysis by Bongartz et al" doc
... Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V: Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies Systemic review and meta-analysis ... effects in randomized controlled trials JAMA 2006, 295:2275-2286 Stern R, Wolfe F: Infliximab dose and clinical status: results of studies in 1642 patients with rheumatoid arthritis J Rheumatol 2004, ... 31:1538-1545 Remicade label information [http://www.remicade.com/global/ hcp/hcp_PI.jsp] Lagakos SW: Time -to- event analyses for long-term treatments: The APPROVe trial N Engl J Med 2006, 355:113-117 Page...
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A study on ambiguity caused by ellipsis and substitution in english = nghiên cứu về sự mập mờ về nghĩa gây ra do phép tỉnh lược và phép thay thế trong tiếng anh luận văn tốt nghiệp đại học
... caused by ellipsis and substitution • Give some recommendations and suggestions for avoiding ambiguity caused by ellipsis and substitution • Give some ellipsis and substitution exercises to practice ... are related to ellipsis and substitution 2.3 Survey Result and Data Analysis After carrying out the survey, collecting and processing the data, the author has gained following result: Section ... caused by the usage of words and sentence structures This makes learners at all levels, from elementary to university or even at higher levels, difficult to understand and to interpret English into...
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Tài liệu JQuery: Novice to Ninja by Earle Castledine and Craig Sharkie pptx
... jQuery: Novice to Ninja by Earle Castledine and Craig Sharkie Copyright © 2010 SitePoint Pty Ltd Program Director: Andrew Tetlaw Indexer: Fred Brown Technical Editor: Louis Simoneau Editor: Kelly ... elements on a web page, and helping out with Ajax requests Sure, there are quite a few commands available to this—but they’re all consistent and easy to learn Once you’ve chained together your first ... some CSS concepts that are key to understanding jQuery, and briefly touch on the basic syntax required to call jQuery into action Chapter 2: Selecting, Decorating, and Enhancing Ostensibly, jQuery’s...
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Tài liệu Law of Attraction - How to Attract Money, Love, and Happiness By David Hooper pptx
... different people One is active, one is passive One is cool and one is hot Although these differences seem to exist on the surface, couples that stay together also have something more and this underlying ... peace and bliss.18 Eckhart Tolle’s experience of the “void” was an extremely profound experience and one that he seemed to attract into his life before he found the ability to overcome it and thereby ... applied to larger and larger visions of the universe such that we can expand our own consciousness to greater and greater perspectives The manner in which we this is through an intimate understanding...
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Tài liệu Formal and informal institutions’ lending policies and access to credit by small-scale enterprises in Kenya: An empirical assessment doc
... not ensure efficient and profitable use of credit funds, especially by farmers, and also result in a disparity between credit demand and supply (Atieno, 1994) This view is further supported by a ... borrowing seems to suggest borrowers’ response to the low supply of credit, and information asymmetry in the market Borrowers respond to the limited supply by directing their demand for credit to specific ... arrangements to adjust to changing economic circumstances, and reducing the transaction costs to the borrowers who respond by maintaining discipline in order to sustain their access to credit The result...
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21st Century Welfare: Presented to Parliament by the Secretary of State for Work and Pensions by Command of Her Majesty pptx
... designed to reach • The burden of consultation Keeping the burden of consultation to a minimum is essential if consultations are to be effective and if consultees’ buy-in to the process is to be ... underlying issue and entitlement to benefit paid by one agency affecting the benefit payable by another; and • o administer – where people may need to provide the same information t to different ... unnecessary customer contacts, at a cost to both the customer and the taxpayer, and creates potential for error and fraud 31 When people move into work, delays in payment can occur as claims stop and start...
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Báo cáo khoa học: ` Inhibition of human ether a go-go potassium channels by 2+ Ca ⁄calmodulin binding to the cytosolic N- and C-termini potx
... peptide C2, EF-hand mutations and increased the KD by about a factor of seven (to 1560 ± 190 nm compared to 223 ± 44 nm for the wild type); EF-hand mutations and resulted in a complete loss of ... as for BD-C2, lack of EF-hand motifs and only resulted in a mild reduction of binding (factor and 9, respectively), while EF-hand motifs and were essential The same results were obtained for functional ... Topology of the hEAG1 channel subunit consisting of six transmembrane segments and extended cytosolic N- and C-terminal domains Functional channels are formed by of such subunits involving the C-terminal...
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Báo cáo khoa học: Fluorescence quenching and kinetic studies of conformational changes induced by DNA and cAMP binding to cAMP receptor protein from Escherichia coli ppt
... data enabled us to resolve the spectrum into components according to (Eqn 2) The quenching data were tted to the SternVolmer equation according to a one- component or a two-component model The ... lifetime measurements of the CRPW85A mutant and its complexes with cAMP and DNA were conducted using an excitation wavelength equal to 295 nm Phase and modulation were analyzed by using single- and double-exponential ... Judging by the calculated v2 value and the residual distribution, the phenomenon can be described by a two-component model in which one component in the protein is more available for the quencher and...
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Recent Advances in Immunology to Target Cancer, Inflammation and Infections Edited by Jagat R. Kanwar ppt
... into viral persistence and failed to produce effector cytokines such as IL-2 and TNF- Recently, IL-21 was identified as an essential component of CD4+ T cell help to sustain CD8+ T cell effector ... IL-7, and IL-1 were measured by Lincoplex assay, IFN- was measured by bead array, and TGF-1 was measured by ELISA Their analysis revealed statistically significant differences between cases and ... sufficient to drive CD8+ T cell exhaustion." J Immunol 182(11): 6697-6708 Viruses Strive to Suppress Host Immune Responses and Prolong Persistence 37 Byrne, J A and M B Oldstone (1984) "Biology of cloned...
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Báo cáo khoa học: Pherokine-2 and -3 Two Drosophila molecules related to pheromone/odor-binding proteins induced by viral and bacterial infections ppt
... by HPLC and the molecule induced by the viral infection was detected by MALDI-TOF MS (Fig 2B) The molecule was purified to homogeneity by gel permeation and reversed-phase chromatography and submitted ... at 214 nm and the fractions were handcollected and analyzed by MALDI-TOF MS Three purified fragments were submitted to automated Edman degradation on a pulse liquid automatic sequenator (Applied ... infected by septic injury, and expression of phk genes was analyzed by Northern blot (C) phk-3 Expression is upregulated by LPS (+) and repressed by the molting hormone ecdysone in S2 tissue-culture...
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Báo cáo khoa học: pyr RNA binding to the Bacillus caldolyticus PyrR attenuation protein – characterization and regulation by uridine and guanosine nucleotides potx
... pyr RNA, as shown by the failure of a control RNA (i.e the antisense strand to BcBL1) to bind to any concentration of PyrR tested (Fig 2A) Binding of PyrR to BcBL2 and BcBL3 in standard binding ... DB104 DB104 DB104 DB104 DB104 DB104 DpyrR DB104 DpyrR DB104 DpyrR None 50 None 50 50 50 None 50 None None None 50 50 10 None None 50 86 120 56 47 110 130 1300 1300 1400 FEBS Journal 275 (2008) ... observed by the gel shift method (Figs 2D,E and 3, Table 4) The binding of BcBL1 to PyrR was clearly resolved into two phases (Fig 2D), one corresponding to tight binding (Kd1 in Table 4) and another...
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Báo cáo khoa học: DNA mediated disassembly of hRad51 and hRad52 proteins and recruitment of hRad51 to ssDNA by hRad52 pot
... nucleotide cofactors and later subjected to centrifugation and the resulting pellet and supernatant were analysed by SDS PAGE followed by silver staining (C) Dynamic light scattering to study the ... dithiothreitol (DTT)] at 37 °C for h Samples were subjected to centrifugation at 14 000 r.p.m for 10 The supernatant and pellet were separated and heated in Laemmli buffer at 90 °C for 10 and analysed by ... incubated in binding buffer in the absence (lanes and 3) or presence of 75 lM ssDNA (lanes and 5) and mM ATP (lanes and 5) for h at 37 °C and then subjected to partial digestion with trypsin (Sigma,...
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chemical sensing and catalysis by one - dimensional metal - oxide nanostructures
... (a) A large surface -to- volume ratio means that a significant fraction of the atoms (or molecules) in such systems are surface atoms that can participate in surface reactions (b) The Debye length ... steps (such as the nanowire growth, application and removal of a photoresist, deposition of electrodes) where the surface (and bulk) of the nanowires and the surrounding area are exposed to reactive ... simplicity, we imply O S to be the dominant chemisorbed species, although both single atom and diatomic species are known to exist on the surface under appropriate conditions Bottom: The calculated...
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Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... the effector caspase and caspase suggests that hDlg could be proteolysed by one of them To check this, HeLa cells were treated with or without the general caspase inhibitor z-VAD prior to and during ... protein levels and whether this was dependent on cell density To avoid cell death caused by long exposure to hyperosmotic shock, cells were treated for 60 with sorbitol and then released into fresh ... releasing it from the cytoskeleton into the cytoplasm [3] Our aim in this study was to gain a better understanding of the role of hDlg phosphorylation by p38c when cells are exposed to hyperosmotic stress...
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Báo cáo khoa học: Caspase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7 pot
... legend to Fig (D) The indicated combinations of caspase, fluorogenic substrate and inhibitor were mixed together and the fluorescence resulting from the caspase-mediated substrate cleavage was monitored ... part by their inhibition of caspases-3, -7 and -9 [30] Other mammalian caspases (-1, -6, -8 and -10) are known to be resistant to inhibition by IAPs [30], but the susceptibility of caspase-2 to ... particular we focused on the susceptibility of caspase-2 to suppression by 1402 P.-k Ho et al known caspase inhibitors and the ability of caspase-2 to activate effector caspases In addition, we...
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A Step-by-Step Guide to SPSS for Sport and Exercise Studies potx
... files, and select specific cases, as well as how to create and edit a variety of different tables and charts The book uses clear step -by- step demonstrations to show how students can carry out and ... inappropriate option, or omit an important option, and obtain inappropriate results Even when the procedure is correct, one needs to be able to understand and use the most important parts of an output ... Commands in the Log SPSS will then present in the Output menu the commands 20 Data handling for any analysis that you will subsequently carry out The commands can be copied and pasted onto a...
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Mechanical impedance to root growth: a review of experimental techniques and root growth responses pot
... factor of between and by which penetrometer resistance exceeds root resistance is sufficient to remove any apparent discrepancy Similarly, the factor of between and 10 by which resistance to root ... where root diameter measured 3t05 I* to 4t08 4.5 to 2.6 to 5.3 1.8 to 3.8 4.5 to 12 120 324 14 ratio (orobe resistance) (root resistance) Number of replicates *Root diameter was also measured ... roots, water extraction by roots, root swelIing and root nutation Because roots seldom grow through soil in complete isolation, it is important to consider interactions between neighbouring roots...
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Population structure attributable to reproductive time: isolation by time and adaptation by time docx
... provided by J McKay, L Rieseberg, L Rowe, R Shaw, and B Sinervo A Hendry and T Day are supported by the Natural Sciences and Engineering Research Council of Canada Supplementary material The supplementary ... microsatellite loci: One1 , One2 , One8 , One1 1, One1 4, and Ots103 (Scribner et al 1996; Nelson & Beacham 1999) We then calculated FST/(1−FST) between all pairs of samples (as suggested for IBD by Rousset 1997), ... Washington: October, 20 October, November, 20 November, and December (A Hendry, P Bentzen, I Spies and K Fresh, unpublished) We genotyped 45–53 fish from each sample at six microsatellite loci: One1 ,...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25