blessed be the tie that binds lyrics and chords
Báo cáo khoa học: Sugar and alcohol molecules provide a therapeutic strategy for the serpinopathies that cause dementia and cirrhosis pot
Ngày tải lên :
30/03/2014, 11:20
... with the enzyme, the reactive loop
of the serpin is cleaved and the molecule undergoes
a profound conformational transition that swings the
proteinase from the upper to the lower pole of the
serpin ... involving the carbonyl groups
of Asn186 and Leu184, and also binds Ser56 of
helix B. It is likely that the larger erythritol molecule
is required to form sufficient hydrogen bonds
between strands 3 and ... stabilize the mutant pro-
tein against polymerization.
The Z mutation of a
1
-antitrypsin is located, not in
the shutter domain, but at the head of strand 5 and
the base of the reactive centre loop. The...
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Báo cáo y học: "The association of meat intake and the risk of type 2 diabetes may be modified by body weight"
Ngày tải lên :
31/10/2012, 16:49
...
may not be directly generalizable to the general
population.
To better understand the relationship between
the intake of meat and the risk of type 2 DM we
prospectively investigated the association ... To our
knowledge there are no other reports of a direct link
between poultry consumption and risk of diabetes or
of interactions between poultry consumption and BMI
and the risk of type 2 ... [3;5-7]. The available data on the association
between meat intake and the risk of type 2 DM are
limited to four health professionals cohorts and the
Seventh Day Adventist cross-sectional study and...
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Programming the Be Operating System-Chapter 9: Messages and Threads
Ngày tải lên :
17/10/2013, 19:15
... handler simply handles the message and doesn’t return any
type of reply). While the poster of the message and the target of the message don’t
have to be one and the same, they can be as shown in ... *message,
BHandler *handler,
BHandler *replyHandler = NULL)
The first parameter, message, is the BMessage object to post. The second parame-
ter, handler, names the target handler the BHandler object ... alertString);
The beepOnce variable will be used to specify whether or not a beep should
accompany the display of the alert. The alertString holds the text to be dis-
played. Once created and set up, the...
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Vision and Mission The Two Key Anchors That Add Passion and Purpose to Your Story
Ngày tải lên :
24/10/2013, 09:20
... setting the vision and facilitating the executive team
in developing the vision statement and ultimately, for being the
cheerleader for the field of vision. The president of the company is
the number-one ... buyers become home owners.
This mission hits both levels of sophistication. The customers
connect with both the product and the partnership between them
and the builder. The employees understand the ... by a
voice that told him, “Build it and they will come.” His character
then began a quest to find out what that voice meant. In the begin-
ning he had no clue, just a belief that the message...
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Tài liệu Programming the Be Operating System-Chapter 6: Controls and Messages ppt
Ngày tải lên :
26/01/2014, 07:20
... and that view
becomes the recipient of keystrokes. Once a text field is the focus view (as indi-
cated by the editable text field being highlighted and the I-beam appearing in it),
and once that ... below the top view, telling you that this view has been added to the
window. The BButton fButtonBeep1 view and the BView radioGroupView lie
directly below the fMyView view, so you know that each ... *buttonBeep1Name = "Beep1";
const char *buttonBeep2Name = "Beep2";
const char *buttonBeep1Label = "Beep One";
const char *buttonBeep2Label = "Beep Two";
In the...
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Tài liệu The Things that Make Me Weak and Strange Get pptx
Ngày tải lên :
17/02/2014, 04:20
... knees, the palms of his hands. His
hands and knees had been sanded raw and there was grit and glass and
bits of pebble embedded under the skin, which oozed blood.
His thoughts wanted to return to the ... that said, “Don’t
screw with me.” But once they passed the threshold of their building and
the door closed behind them, their whole affect changed. They slumped,
they smiled at one another, they ... pointless flamewars about the ethics of
working for the Securitat, and then had settled into being a very
16
that let them keep the hierarchy nice and flat, the way that they all liked
it. Authority...
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Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx
Ngày tải lên :
18/02/2014, 06:20
... ath-
erosclerosis and that ectopic fat in the liver, and not
visceral fat, may be responsible for this phenotype.
Androgen measurements in these metabolically benign
obese patients may provide further clues ... discuss the link between obesity and
ED by focusing on the potential pathophysiological
links including obesity-related androgen deficiency and
obesity-induced endothelial dysfunction.
Obesity ... reported
that obese patients with ED had reduced SHBG-bound
and unbound testosterone levels even after adjusting
for obesity-related comorbidities. The authors sug-
gested that obesity itself may be the...
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Tài liệu Báo cáo khoa học: Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits ppt
Ngày tải lên :
21/02/2014, 03:20
... could be quantified by
phosphorimaging of the band corresponding to the full-
length protein, and normalizing to the Coomassie blue
staining of the same band.)
It was next demonstrated that the ... fractions
(Fig. 6), and the finding that the electrophoretic mobility of
the phosphorylating kinase corresponds to that of the a
subunit of CK2 (Fig. 9). However, other experiments
aiming to detect the b subunit ... also be
interrelated [29]. Taken together with the fact that the
phosphorylation does take place also in whole cells, is
characterized by a K
m
of 1.4 l
M
, and that the kinase
tightly binds...
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The Clock that Had no Hands The Clock that Had no Hands And Nineteen Other Essays About Advertising doc
Ngày tải lên :
05/03/2014, 16:20
... “alley-dwellers.”
43–44
How Alexander Untied the Knot
45
How Alexander Untied the Knot
Alexander the Great was being shown the Gordian Knot. “It can't be untied,” they told
him; “every man ...
PAGE
The Clock that Had no Hands 1
The Cannon that Modernized Japan 7
The Tailor who Paid too Much 13
The Man who Retreats before His Defeat 19
The Dollar that Can't be Spent 25
The ... solid muscle and sinew—all pull. It isn't the number of
copies printed but the number of copies 95–9 6that reach the hands of buyers—it isn't
the number of readers but the number of readers...
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Báo cáo khoa học: The signature amidase from Sulfolobus solfataricus belongs to the CX3C subgroup of enzymes cleaving both amides and nitriles Ser195 and Cys145 are predicted to be the active site nucleophiles pot
Ngày tải lên :
07/03/2014, 21:20
... synthesized. Forward and reverse primers correspond
to the first 20 nucleotides at the 5Â- and 3Â- of the gene cod-
ing sequence and include the NcoI and BamHI sites, at each
end, respectively. The ... at pH 7.4 and T ¼ 70 °C using 61 lg purified protein. Activity was measured with the Berthelot assay, by reading the
absorbance of the colour developed at k ẳ 630 nm.
b
Benzamide and benzonitrile ... mutagenesis
and their activity assayed with the colorimetric method
of Berthelot, appropriately modified for the assay con-
ditions of the archaeal enzyme. This assay is based on
the measurement of the...
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Báo cáo Y học: The phosphotransferase system of Streptomyces coelicolor IIACrr exhibits properties that resemble transport and inducer exclusion function of enzyme IIAGlucose of Escherichia coli pptx
Ngày tải lên :
17/03/2014, 23:20
... IIA
Crr
should be mentioned here. Ueguchi and coworkers have
reported that E. coli IIA
Glc
controls the sigma factor of the
general stress response RpoS [14]. They suggested that this
could be a linkage between ... We provided evidence that the gene
is expressed in vivo and that IIA
Crr
is phosphorylated in vitro
by the general PTS phosphotransferases EI and HPr. IIA
Crr
could replace the functions of E. ... glucose
transport and inducer exclusion. These findings suggest that
IIA
Crr
might be involved in carbohydrate transport and
C-regulation in S. coelicolor.
The crr gene of S. coelicolor shares the highest...
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Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt
Ngày tải lên :
18/03/2014, 01:20
... purified
protein fraction, shows the binding of the promoter with the
p40 protein and not with PsCCaMK (Fig. 7). The absence
of binding with PsCCaMK could be due either to the fact
that it does not bind ... low
yield and the eluted protein was highly labile.
The 40-kDa protein is phosphorylated by PsCCaMK
and binds directly with the
AtCaM5
promoter
As p40 remains tightly bound to the PsCCaMK during
the ... species
and it has been shown that their binding with DNA is
affected by the phosphorylation status of the proteins [56–
58]. In animal systems it has been shown conclusively that
these proteins...
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The World That Couldn''''t Be pdf
Ngày tải lên :
23/03/2014, 00:20
... place. Following the gash cut by the slide, they clambered up the
slope and finally reached the point of the slide's beginning.
There they found the depression in which the poised slab of ... moment in his life were the only one that coun-
ted; as if all the minutes and the hours, all the breaths and heartbeats,
22
And he held the trigger tight and kept his crouch so the slugs would
not ... the fire and he tried with trembling fin-
gers to restore them to the shape they'd been before the bullets struck
them. And that was a good one, he thought with grim irony, because
they had...
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Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt
Ngày tải lên :
23/03/2014, 04:20
... frag-
ment was used to compete for the binding
of the GST protein to the labeled probe (+).
Labeled DNA was detected by autoradiogra-
phy. The positions of the free probe and the
shifted GST-CXC protein ... on
ice with the indicated antibodies before the addition of the
probe. The a-LIN9 antiserum has been described previously
[12]. The LIN54 antiserum was raised in rabbits against the
peptide AAKTKLSSQISDLLTR. ... observation
that soybean CPP1, a member of the family, binds to
the promoter of the leghemoglobin gene Gmlbc3
through the cysteine-rich domains [25]. Moreover,
Mip120, the Drosophila LIN54 protein of the...
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