... critical illness and shorter intensive care unit and hospital lengths of stay and interpretation, and drafting of the manuscript WIJ participated in data acquisition and drafting of the manuscript SKE ... using a Kaplan-Meier survival analysis The subjects in the two randomly assigned groups were analyzed using the intent-to-treat principle Statistical significance was determined using a log-rank ... paired sedation and ventilator weaning protocol for mechanically ventilated patients inintensive care (awakening and breathing controlled trial): a randomised controlled trial Lancet 2008, 371:126-134...
... dilutions and infusion rates to be specified By adding and storing the order at this point (mandatory and requiring entry of a unique six digit alpha/numeric password) the clinician's name and initials ... prescribing or adminis- tering a medication Start and stop dates and changes in dose were always recorded and identifiable in comparison with handwritten prescriptions where changes in doses ... Classen DC, Evans RS, Burke JP: Implementing antibiotic practice guidelines through computer-assisted decision support: clinician and financial outcomes Ann Intern Med 1996, 124:884-890 Winslow EH,...
... clinical sedation scores during mechanical ventilation in the pediatric intensive care unit Anesth Analg 2002, 94:506-511 Crain N, Slonim A, Pollack MM: Assessing sedation in the pediatric intensive ... corresponding consciousness level during emergence from anaesthesia in a prospective, blinded manner in children (≥1 year old) and infants (
... data J-MB and RQ were involved in drafting the manuscript and revising it critically for important intellectual content References Using pulse field gel electrophoresis, an Enterobacter cloacae ... [8] The weight of the patient then caused bacteria-containing aerosols, which contaminated the patient s surroundings despite daily cleaning of the cover, thus generating transmission We believe ... isolates (lanes 1–4) and six clinical isolates (lanes 5–7, 9, 11 and 18) Figure Photographs of a 6-month-old therapeutic bed (a) Stained mattress foam where the patient was situated (b) Stained mattress...
... the literature review and the writing, drafting, and editing of the manuscript, including the creation of tables TDG assisted in the writing, drafting, and editing of the manuscript EWE contributed ... literature review, and was primarily responsible for writing the manuscript RPH assisted in the conception of the project and in the writing and drafting of the manuscript, including the creation ... assisted in performing the literature review and in the writing and drafting of the manuscript, including the crea- Key messages • PTSD or PTSD symptoms are reported to occur in between 5% and 63%...
... delirium and does not allow one to assess severity Ease of administration and acceptance by the nursing and physician staff are critical to any implementation of delirium screening inan ICU setting ... instruments can be found in a recent review article [3] The patient population is important when choosing a delirium screening instrument for clinical care or research and also needs to be kept in mind ... emerging on the practicalities of using delirium screening instruments in the ICU A study by Pun and colleagues demonstrated the ability to implement CAM-ICU screening and documented nursing acceptance...
... glucose and creatinine concentrations, as well as prothrombin time Patient population The patients were divided according to their 28-day outcome in order to investigate if there were differences in ... not easy and of no value because metformin is essentially an intracellular toxin Moreover, as any concentration of metformin may impair liver lactate clearance, it is worth considering that the ... critically ill patients [3] We found that MALA was present in about 1% of patients admitted to the ICU, and indeed metformin is a factor that is detrimental to the outcome in the setting of an acute...
... and the urinary volume, and the decrease in creatininemia and bilirubinemia In a second clinical trial, Heemann and colleagues [11] randomized 24 patients with severe cholestasis (bilirubin > 20 ... decrease in intracranial pressure, and an increase in cerebral perfusion pressure, mean arterial blood pressure, systemic vascular resistances and cardiac index [17,18] Currently we are undertaking ... blood-contacting tubes and membranes that are used extensively in 24 h hemodiafiltration treatment inintensive care unit patients and the dialysate solution is supplemented with approved human albumin...
... if there was a blue line in the control window and a pink line in the test window, and negative if there was a blue line in the control window and no pink line in the test window Serological study ... without bleeding (Table 3) Survival was significantly better in patients without bleeding than in patients with clinical evidence of bleeding during their ICU stay (p < 0.001) Using multivariate analysis, ... [13,14,19] In two studies involving, respectively, 229 and 301 patients in cardiosurgical intensive care units, no link was found between H pylori serostatus and upper gastrointestinal bleeding [14,19]...
... Chalfin DB, Phillips G, Danis M: Association between critical care physician management and patient mortality in the intensive care unit Ann Intern Med 2008, 148:801-809 Brilli RJ, Spevetz A, Branson ... increase in intensivist staffing To date, however, there are few studies describing the mechanisms through which high intensity physician staffing inan ICU improve patient outcomes Establishing that ... rounding † excludes patients (n = 52) cared for in the federal hospital in King County ||Data missing for 12 (4%) of patients in open ICUs and 32 (7%) of patients in closed ICUs ALI = acute lung injury;...
... Selection of intensive care unit admission criteria for patients aged 80 years and over and compliance of emergency and intensive care unit physicians with the selected criteria: an observational, ... long-term mortality in very elderly patients admitted to anintensive care unitIntensive Care Med 2006, 32:1039-1044 12 Ware JE Jr, Snow KK, Kosinski M: In SF-36 Health Survey Manual and Interpretation ... relations and spending time by oneself increased with increasing age, suggesting that ‘quality of life’ has a different meaning for older individuals than it does for younger ones In ICU patients,...
... vitamin D status including plasma levels of 25(OH)D and vitamin D binding protein (DBP) and their relationship to systemic LL-37 levels in a group of critically ill patients including those with and ... LL-37 and restored effective killing of M tb, suggesting that vitamin D has an important role in the production of anti-microbial peptides important for innate immunity [3] Patients with severe infections ... D and its metabolites, providing another mechanism to explain why vitamin D insufficiency is common in patients with sepsis The classic function of vitamin D is to maintain optimal calcium and...
... patient care and edited the manuscript All authors read and approved the final manuscript Acknowledgements We want to thank the nursing and ancillary staff of the intensive care unit at the Patras ... intravenous Mg therapy for tetanus come from developing countries such as Sri Lanka [11] and Vietnam [14] In most published cases, intravenous Mg therapy was used inan attempt to avoid mechanical ... high-dose intravenous Mg infusion therapy is effective in managing tetanus and can be implemented without major toxicity However, Mg therapy can be associated with serious adverse effects, and our...
... approximately h, acquiring simultaneous paired cardiac index data points at 1-min intervals The data points were analysed using SPSS for Windows release 6.1 (SPSS Inc, Chicago, Illinois, USA) and r was calculated ... reliability in ICU patients [9,10] Correct placement of the eight electrodes is important in obtaining accurate information; in ICU patients this may be hampered by dressing covering internal jugular line ... output in patients in the ICU and upon which much of our understanding of the cardiovascular changes in critical illnesses is based Bioimpedance cardiography has been validated in some patient...
... difficile, and an increase in clindamycin susceptibility among C difficile strains Although this lead to increased use of antibiotics with anti-anaerobic activity, including cefotetan, ticarcillin-clavulonate, ... for specific indications and risk-stratified patient groups becomes better identified in the hospital setting [26] using gloves and chlorhexidine soap for hand washing, and eliminating electronic ... nosocomial infection inintensive care units in Europe: results of the European Prevalence of Infection inIntensive Care (EPIC) Study; EPIC International Advisory Committee JAMA 1995, 274:639-644 Hanberger...
... study found reductions in the minimum inhibitory concentrations, representing a progressive increase in the antimicrobial activity of antibiotics [31] While in vitro data and animal data seems to ... mechanisms include active transport of cytokines into the OVLT or activation of cytokine receptors in endothelial cells of the neural vasculature, which than transduce signals to the brain [19] ... (e.g heat) and can protect against cell death from an entirely different lethal stress (e.g endotoxin) [34] HSPs have subsequently been found in numerous organisms, and the DNA sequencing and subsequent...
... ICU We were especially interested in whether acid–base analysis according to the physicochemical approach could result in important changes in diagnosis, and therefore intherapy We hypothesised ... strong anions that are almost universally present in these patients Competing interests None declared Key messages • Metabolic acidosis inintensive care unit patients is usually explained by ... in the circulation during sepsis and liver failure, and may be a variety of organic and inorganic compounds [8] The use of urealinked polygelines, for example, as the priming fluid for the extracorporeal...
... Muellejans et al Introduction The provision of effective analgesia and sedation for patients in the intensive care unit (ICU) is important in controlling pain, relieving agitation and anxiety, and ... eight in Germany, one in The Netherlands, four in Spain, four in the UK) In total, 152 patients were randomized, in a double-blind manner, to receive either a remifentanil based regimen or a standard ... without pain was treated either by reducing or by discontinuing the propofol (if being administered) or opioid infusion Pain was treated with an opioid bolus dose and an increase in the opioid infusion...