black scholes is used in practice volatility smiles
Structured Finance doc
... old intermediation business To explain, take the simplest financial product you may imagine, a zero coupon bond, i.e a product paying interest and principal in a single shot at the end of the investment ... replicating portfolio argument even further In principle, a derivative may be considered as a structure including a long or short position in a risk factor against debt or investment in the risk-free ... which is the risk profile of the product? Is there some class of investors or borrowers that may be interested in such risk profile; that is, which is the demand side for this product? Finally,...
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THE structure of the multiprogramming system
... semaphore concerned is nonpositive, one of the processes booked on its waiting list is removed from this waiting list, i.e its dynamic progress is again logically permissible and in due time a processor ... that could be held in core If building up the line printer output streams had been implemented as "dumping onto the drum" and the actual printing as "printing from the drum," this advantage would ... value resulting from a Voperation is negative, its waiting list originally contained more than one process It is undefined i.e, logically immaterial-which of the waiting processes is then removed...
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Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf
... at the interface of the two domains, which consists of four side chains: two (His31 and His79) from the N-terminal domain and two (Asp165 and His169) from the C-terminal domain (Fig 3) In Mn-reconstituted ... grouped into four classes according to their metal cofactors: copper and zinc-containing SOD (Cu,Zn-SOD), iron-containing SOD (Fe-SOD), manganese-containing SOD (MnSOD) and nickel-containing SOD ... [37] and confirmed visually using coot [42] Ion˚ pair interactions were identified using distances < A When we counted the interactions, we excluded all residues involved in the binding of the metal...
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Tài liệu High-level Expert Group on reforming the structure of the EU banking sector docx
... since the financial crisis Banking sector restructuring, deleveraging and derisking Given the severity of the crisis, one may have expected a rapid restructuring of the banking sector, including ... developments in the years leading up to and since the financial and economic crisis It starts with a brief crisis narrative outlining the different "waves" of the crisis since it started in 2007 It ... closes by assessing EU bank restructuring (de-risking, deleveraging) going forward, as well as the broader consequences in terms of bank disintermediation and risks of financial disintegration Chapter...
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Tài liệu Báo cáo khoa học: Structure of the putative 32 kDa myrosinase-binding protein from Arabidopsis (At3g16450.1) determined by SAIL-NMR docx
... myrosinase-binding protein-like protein Myrosinase is a glucosinolatedegrading enzyme [4], and myrosinase-binding protein (MyroBP) has been identified as a component of high-molecular-mass myrosinase ... to N-acetylglucosamine [10] Because myrosinase contains potential N-linked sugar-binding sites [23], the sugarbinding activity of MyroBP is implicated in binding to myrosinase In the case of At3g16450.1, ... domain of the MyroBP family possesses different ligand-binding properties, thereby providing a broad binding specificity In some proteins containing tandem homologous domains, inter-domain interactions...
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Tài liệu Báo cáo khoa học: Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family pptx
... domain in hepsin (Fig 5A) This conformation does not seem to be an artifact of the missing N-terminal domain because in DESC1, as well as in matriptase, the conformation of this residue is stabilized ... inhibition by serine proteinase inhibitors (serpins) The serpins form a family of homologous, large (glyco-) proteins comprising about 400 amino acid residues Serpin inhibitors interact with their ... P1 to P4 are indicated in bold 2156 Inhibition of DESC1 Regulation of proteolytic activity by Kunitz-type inhibitors is commonly observed in trypsin-like serine proteinases, including the TTSP...
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Tài liệu Báo cáo khoa học: Crystal structure of the BcZBP, a zinc-binding protein from Bacillus cereus doc
... not shown) The zinc-binding motif is of the type HXDD(X)98H (residues in bold are zinc ligands; X is used to represent any residue) Such a motif, with the first two zinc ligands being separated ... predicted in the crevice adjacent to the C-termini of strands b1 and b4 In this crevice of each monomer, a prominent electron density peak (at 13 r in a 2Fo–Fc map) was found Interestingly, there is ... As zinc compounds were not used in the purification or crystallization protocols, we conclude that the metal must be intrinsically contained in the protein The structure of the active site is illustrated...
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Tài liệu Báo cáo khoa học: Spectroscopic characterization of a higher plant heme oxygenase isoform-1 from Glycine max (soybean) ) coordination structure of the heme complex and catabolism of heme docx
... (a-1 in Fig 3), indicating that in- plane anisotropy of heme is relatively large In addition, small amounts of low-spin species are also observed in the neutral solution, as distinctly seen in the ... position in which it is present in SynHO-1 (His17) or rHO-1 (His25) Instead, there is only one His (His30) in the predicted proximal A-helix region (Fig 1) Experiments on heme binding to GmHO-1 have ... proximal ligand, indicating hyperfine splitting due to a 14N nucleus (nuclear spin 1, giving the triplet splitting) in addition to a 15N nucleus (nuclear spin ⁄ 2, giving the doublet splitting) at the...
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Tài liệu Báo cáo khoa học: Unusual metal specificity and structure of the group I ribozyme fromChlamydomonas reinhardtii23S rRNA pptx
... ribozyme indicating that the metal requirement for ribozyme folding is less restrictive than that for catalysis [14,15] It is also surprising that Mn2+-induced misfolding of this ribozyme is highly ... explanation for this result is that binding of GMP prevents an inhibitory Mn2+ from binding to this site Interestingly, 2Â-dGTP inhibits Pb2+ cleavage of the T4-td intron at the bulge nucleotide in P7 [30], ... Thus, formation of the inactive ribozyme is highly cooperative The data also suggest that binding of a minimum of six Mn2+ ions is involved in the misfolding that forms the inactive ribozyme Structure...
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Tài liệu Báo cáo khoa học: Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Structure of the reduced enzyme-progesterone complex and the roles of residues Tyr186, His181 and His184 pdf
... analysis of the contribution of each histidine residue to binding and catalysis Thus, to ascertain the role of each histidine residue, and to identify any differential contribution to binding and ... implicated in ligand binding Solution studies with MR [25] and OYE1 [26], which contain a His-Asn pair at this position support this inferred role, and the data reported in this paper indicate ... 2-cyclohexen-1-one indicate that these ligands bind above the si face of the FMN isoalloxazine ring and are held in position by hydrogen bond interactions with His181 and His184 [2] These residues also form interactions...
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Tài liệu Báo cáo khoa học: Solution structure of the matrix attachment region-binding domain of chicken MeCP2 ppt
... syndrome is caused by mutation in X-linked MECP2, encoding methyl-CpG-binding protein Nat Genet 23, 185–188 13 Chen, R.Z., Akbarian, S., Tudor, M & Jaenisch, R (2001) Deficiency of methyl-CpG binding ... an X-linked, dominant neurological disorder primarily affecting young girls [12] Intriguingly, six missense mutations cluster in the helical coil a2/a3, emphasizing the importance of this region: ... (right) proteinÆDNA interactions Chemical shift changes furthermore indicate that residues close to the N-terminus and C-terminus also contribute to these interactions In this study, we used a nonmethylated...
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Tài liệu Báo cáo khoa học: The structure of the carbohydrate backbone of the lipopolysaccharide from Acinetobacter baumannii strain ATCC 19606 docx
... octasaccharide, this amino group is not acetylated and H-2 of the residue G resonates at 3.264 p.p.m., whereas in the tetrasaccharide this aminogroup is acetylated, thus, this signal is shifted to ... desalted using a Dowex 50 ´ (H+) cation exchanger in water, and amino-group containing compounds were then eluted with 5% aqueous ammonia GLC-MS, monosaccharide analysis, and the determination of ... Acinetobacter strains have been characterized during this work Two of these core regions (i.e of LPS from A haemolyticus strain ATCC 17906/NCTC10305 and from Acinetobacter strain ATCC 17905) have in common...
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Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx
... chain Correlations of the b-linked sugars in the main chain were difficult to interpret because of close positions of the H1 resonances and multiple coincidences of intraresidue H1/H3,H5 and interresidue ... the complete set of Proteus strains, including 37 strains of P mirabilis and 28 strains of P vulgaris belonging to 49 Proteus O-serogroups as well as 133 strains of P penneri From 188 tested ... which is present in P mirabilis S1959 but absent from P mirabilis G1, and a partial epitope O3c in P mirabilis G1 may be an extended epitope that is masked by the a-D-Glcp residue in P mirabilis...
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Tài liệu Báo cáo Y học: Solution structure of the mEGF/TGFa44250 chimeric growth factor doc
... be induced by spin diffusion and then soften all distance constraints accordingly In effect, this allows for the uncertainty in converting NOE volumes into distances that remains despite having ... maximum or minimum distances obtained by automatic calibration in INDYANA was then used to set a parameter for loosening distance constraints to ensure that the scaling factors, that include the ... 0.0 using 644 distance constraints, 32 dihedral angle constraints and constraints for nine hydrogen bonds Those of 1eph were computed using 355 distance constraints, 24 torsion angle constraints...
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Báo cáo khoa học: Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase Henrik Ingvarsson and Torsten Unge potx
... catalytic domain in red, the CP domain in green, the KMSKS domain in yellow and the anticodon domain in blue The intervening helices a2 and a8 in the catalytic domain are colored cyan The linking p-helix ... unit consists of four domains (Fig 1) [21]: the catalytic domain, the CP domain, the KMSKS domain and an anticodon-binding domain (anticodon domain) The catalytic domain contains the binding pockets ... observed in the anticodon domain The CP domain The CP domain covers the active site in the catalytic domain (Fig 1) It consists of two subdomains: one mainly b and one mainly a A distinctive feature...
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Báo cáo khoa học: Structure of the atrial natriuretic peptide receptor extracellular domain in the unbound and hormone-bound states by single-particle electron microscopy ppt
... containing an extracellular ANPbinding domain (ECD), a transmembrane domain, and an intracellular domain consisting of an ATP-binding regulatory domain and a GCase catalytic domain [8] ANP binding ... juxtamembrane domains in the dimer that is equivalent to rotating each by 24° [9] There is no appreciable change in the distance between the two juxtamembrane domains On the basis of this finding, we have ... et al domains into proximity, thereby mediating signal transduction [14] This proposed mechanism involving a ligand-induced domain approximation has been described in some reports as being well...
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Báo cáo khoa học: Solution structure of the catalytic domain of RICH protein from goldfish pot
... titrations with CNPase inhibitors identified the residues in RICH involved in inhibitor binding and suggest the proteins use a similar catalytic mechanism These findings underline the importance of ... together in the vicinity of the N-terminus This helical patch is the most basic part of the molecule and a potential interaction surface for the preceding acidic N-terminal domain Structural comparison ... of the mechanisms of tRNA splicing involves endonuclease cleavage of an intron-containing tRNA at two exon–intron borders, yielding 2¢,3¢-cyclic phosphates and 5¢-OH termini Following cleavage,...
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