bioprocesses for the manufacture of amino acids tanabe japan

Reference Document on Best Available Techniques for the Manufacture of Organic Fine Chemicals pot

Ngày tải lên : 05/03/2014, 20:20

... account the specific characteristics of the manufacture of Organic Fine Chemicals Using the results of the BREF on CWW as a source of information, the BREF on OFC provides a further assessment of ... in them”, and to publish the results of the exchange The purpose of the information exchange is given in recital 25 of the Directive, which states that the development and exchange of information ... minimisation of environmental impact” (much related to the process design) and the “Management and treatment of waste streams” The former includes strategies for the selection of the synthesis route,...

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Guanidine catalyzed enantioselective mannich reaction towards the synthesis of amino acids

Ngày tải lên : 10/09/2015, 08:31

... TOWARDS THE SYNTHESIS OF  -AMINO ACIDS PAN YUANHANG (BSc., Zhejiang University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CHEMISTRY NATIONAL UNIVERSITY OF SINGAPORE ... precursors for -lactams, various strategies for the stereoselective synthesis of  -amino acids have been reported.16 Amongst these, the most robust and powerful method is attributed to the asymmetric ... ability to form carbon-carbon bonds under mild conditions has been an inspiration and motivation for synthetic chemists For example, the biosynthesis of polyketides required the generation of ester...

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Microbial Production of Amino Acids in Japan

Ngày tải lên : 26/10/2013, 02:20

... successful introduction of the technology, various methods were searched for and developed for microbial production of other amino acids Today a whole array of amino acids are produced by microbial ... biotin for growth Today almost all of these strains are thought to belong to the genus Corynebacterium 73 Microbial Production of Amino Acids in Japan Table Amino acid production in Japan and the ... very low in the presence of the detergent, limited amounts of biotin, or penicillin [5] These results suggest that one of the main causes for glutamate overproduction is the decrease of the 2-oxoglutarate...

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Báo cáo khóa học: Vertical-scanning mutagenesis of amino acids in a model N-myristoylation motif reveals the major amino-terminal sequence requirements for protein N-myristoylation ppt

Ngày tải lên : 16/03/2014, 16:20

... chose Thr and Phe to further analyze the effect of the amino acid residue at position on the amino acid requirement at position because of the presence of these amino acids at position in naturally ... and the amino acid requirements at this position were signiﬁcantly affected by the amino acid at position [25] Therefore, we next determined the effect of the amino acid at position on the amino ... corresponding to each of the 19 amino acids at position were obtained The cDNAs coding for MG3X-TNF, in which the Ala at position in MGA(8)-TNF was replaced with each of the 19 other amino acids, were...

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báo cáo hóa học:" Minireview: Transaminases for the synthesis of enantiopure beta-amino acids" doc

Ngày tải lên : 21/06/2014, 17:20

... thus enabling the synthesis of a wide variety of chiral amines and amino acids Transaminases can be applied either for the kinetic resolution of racemic compounds or the asymmetric synthesis starting ... β -amino acids including (1) the resolution of racemic β -amino acids, (2) the use of naturally occurring chiral α -amino acids, and (3) asymmetric synthesis (Liu and Sibi 2002) As resolutions of ... investigation, there still is no gold standard for the preparation of enantiopure β -amino acids TAs can be applied either in the kinetic resolution of racemic β -amino acids (Fig 2a) or in asymmetric synthesis...

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Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt

Ngày tải lên : 18/02/2014, 13:20

... lack of domain B protruding out of the TIM barrel in the place of loop connecting the b3-strand to the a3-helix [9,21] Sharing domain B by rBATs and GH13 enzymes, and especially the sequence of the ... b2, b3, b4 and b8 of the (b ⁄ a)8 barrel domain, and for rBAT also with the short stretch near the C-terminus of domain B [9,19] From the sequence–structure point of view, the basic difference ... of the hcHAT proteins and the GH13 a-amylase family members The tree is based on the alignment of complete sequences and calculated including gaps The numbers represent the bootstrap values The...

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Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc

Ngày tải lên : 19/02/2014, 16:20

... Enlargement of the original plots shown in (B) present in cell extracts of succinate/glucose-grown cells; therefore, the synthesis of the enzyme was inducible Table shows a summary of a typical ... The decarboxylation mechanism in the metabolic pathways for 3-hydroxyanthralinic acid differs from that in the pathway for 4 -amino3 -hydroxybenzoic acid The N-terminal amino acid sequence of the ... of the 2 -amino- 5-carboxymuconic 6-semialdehyde deaminase from Bordetella sp strain 10d Fractions 1–6 refer to the fractions obtained at the end of steps 1–6 of the puriﬁcation procedure See the...

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Designation: C 465 – 99 - Processing Additions for Use in the Manufacture of Hydraulic Cements1 pdf

Ngày tải lên : 10/07/2014, 23:20

... means for the quantitative determination of the addition in the ﬁnished cement shall be furnished by the sponsor, manufacturer, or supplier of the addition, and the information shall form a part of ... designated the “control” cement 4.4 The amount of the processing addition to be interground with the cement for evaluation purposes shall be determined by the sponsor of the addition 4.4.1 The amount of ... character of the material, and the amount recommended for use, together with means for determination of the proposed addition in the ﬁnished cement, all as furnished by the sponsor, manufacturer,...

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Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"

Ngày tải lên : 25/10/2012, 10:45

... on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the VA population Moreover, we might expect that the PPV and NPV of the ... NC) Results The characteristics of the VARA participants measured at the start of each treatment episode were evaluated Because the characteristics of VARA patients at the start of non-biologic ... contrast to other RA therapies where the drugs are typically discontinued if they are not effective Because of similarities in both the descriptive characteristics of the study populations of biologic...

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Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"

Ngày tải lên : 25/10/2012, 11:40

... attempted for three SPT patients in whom the mass was located in the portion of body or tail of the pancreas For tumors of SPT located in the neck and body of the pancreas, resection of the midportion ... midportion of the pancreas and the mass with preserving the rim of the head and tail portion can be achieved However, for the patient in whom the mass was located within the head of the pancreas, ... 311 Fig The CT scan indicated the typical internal or capsular calcification in the SPT Once the diagnosis of SPT is made, surgery is the first choice of treatment, since other adjuvant therapies,...

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Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique

Ngày tải lên : 26/10/2012, 09:32

... 100% relief of their pain in 86% of the patients with a median relief period of months The range of relief varied from zero days to up to 13 months for the facet injection group None of the lumbar ... median period of pain relief being months The range of relief for the radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure Of the 14 patients ... that the direct visualization of the joint allows better de-innervation of the joint and removal of the entire end-plate receptors that adhere to the bone and capsular tissue Limitations of the...

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Báo cáo y học: "Endoscopic thoracic laminoforaminoplasty for the treatment of thoracic radiculopathy: report of 12 case"

Ngày tải lên : 26/10/2012, 09:57

... or foraminal stenosis treated with endoscopic laminoforaminoplasty via a small incision, of less than one inch Materials and Methods Twelve patients were treated with endoscopic laminoforaminoplasty ... endoscopic laminoforaminoplasty, should decrease the risk of major adverse events, allow for same day hospital discharge, and decrease the need for postoperative analgesia and immobility [5] [6] In the ... cervical laminoforaminotomy for unilateral radiculopathy: results of a new technique in 100 cases J Neurosurg 2001; 95: 51-57 Khoo LT, Fessler RG Microendoscopic decompressive laminotomy for the treatment...

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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

Ngày tải lên : 26/10/2012, 10:04

... system, in the distal segment of the tubule Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target for the control of hyperglycemia ... larvae of beetles (Chrysomelidae) Their synthesis has been previously described [31-33] For the purpose of the present study the thioglycosides used were selected and grouped based on their differences ... IC50 values of 30 µM for hSGLT1 and 10 µM for hSGLT2, while thioglycoside VII showed IC50 values of 15 µM for hSGLT1 and 88 µM for hSGLT2 These data confirm the strong inhibitory effects of thioglycoside...

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Báo cáo y học: "Comparison of a Two-Lead, Computerized, Resting ECG Signal Analysis Device, the MultiFunction-CardioGramsm or MCG (a.k.a. 3DMP), to Quantitative Coronary Angiography for the Detection of Relevant Coronary Artery Stenosis (70%)

Ngày tải lên : 03/11/2012, 10:58

... large inventory of normalized mathematical indexes of abnormality It is the pattern of these mathematical indexes of abnormality, obtained from analysis of multiple cardiac cycles of the resting ... Moreover, to assess the performance of the prediction of stenosis independent of the prevalence of stenosis, the positive and negative likelihood ratios (LR) were calculated [24] A value of p

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A research proposal submitted in partial fulfillment of the requirements for the degree of Master of Business Administration

Ngày tải lên : 13/04/2013, 10:30

... with the supermarkets Along with the actual evaluations of the stores’ performance, the research tries to uncover the shoppers’ expectations of this kind of store In addition, the demographic profile ... level of 90% (app.D, p 84-86) 4.1.10 Demographic profile of supermarkets’ non-users and heavy-users The demographic profile of heavy users in the sample is similar to the profile described for the ... of the store by evaluating the store in terms of the factors comprising the choice criteria Based on the evaluation, the consumer 18 forms a degree of preference for the store If preference exceeds...

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SOME SOLUTIONS FOR THE DEVELOPMENT OF CONSUMER LENDING AT TECHCOMBANK HOANG QUOC VIET

Ngày tải lên : 25/07/2013, 11:20

... Step 3: The director of the branch will responsible for approving the loan application form or not if the value of the loan does not exceed 500 million In case of an exceed, the director of the branch ... expanded the scope and form of lending to customers The orientation of the branch: expanding, strengthening and improving the operational efficiency of the office agency To attract more customers, the ... actually the major activity of the bank Therefore, continuing research and offering solutions would bring enormous significance for both theoretical and practical aspects for the diversification of the...

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Genotoxicity of 255 chemicals in the Salmonella microsome test (Ames test) and 8-hydroxyguanine (8-OH-Gua) assay for the detection of carcinogens

Ngày tải lên : 05/09/2013, 08:40

... supported by the research project The research on the development of the total evaluation technique for the hazardous impacts by the chemical substances towards human and ecology (the project ... and N2- and C8-modified deoxyguanosine as major products of the in vivo reaction of N-hydroxy-6-aminochrysene with DNA and the formation of the adducts in isolated rat hepatocytes treated with 6-nitrochrysene, ... Aflatoxin B1, 2-aminoanthracene, 2-aminoanthraquinone, 3-nitrofluoranthene, 1-nitropyrene, 4-nitroquinoline N-oxide, Cumene, Summary of 255 chemicals for mutagenicity in Ames dibenzyl ether, diethyl...

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Application of Ozone/UV Process for the Reclamation of Sewage Treatment Plant Effluent

Ngày tải lên : 05/09/2013, 08:40

... study, the ozone and UV combination (ozone/UV) process is applied for the reuse of sewage effluent Therefore, the aim of this study is to evaluate the effectiveness of ozone/UV process for the treatment ... reduction of A410 after 10 of run time On the other hand, the UV alone process did not show much color change Therefore, for color reduction, the ozone alone process was considered as the best ... the mechanism of the reaction of ozone with substances in the water can be divided into two distinct pathways (7) The first route is the direct attack of molecular ozone The second route is the...

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