... development oftissue engineering is therefore a relatively recent phenomenon and only in this century has tissue engineering really taken off as a major area of research (Fig 1) Fig Rapid growth oftissue ... hope to believe) Tissue engineering of soft tissues involves different considerations, such tissues generally being much more flexible and much more cellular in terms of the ratio of cells to surrounding ... number of publications returned by a Pubmed search for ' tissue engineering” ' 2 TissueRegeneration – From Basic Biology to Clinical Application Unlike many other young sciences, tissue...
... development oftissue engineering is therefore a relatively recent phenomenon and only in this century has tissue engineering really taken off as a major area of research (Fig 1) Fig Rapid growth oftissue ... hope to believe) Tissue engineering of soft tissues involves different considerations, such tissues generally being much more flexible and much more cellular in terms of the ratio of cells to surrounding ... number of publications returned by a Pubmed search for ' tissue engineering” ' 2 TissueRegeneration – From Basic Biology to Clinical Application Unlike many other young sciences, tissue...
... below, left, and right of the center The percentage maximum magnitude (the maximum magnitude of the measurement area of the operated knee divided by that of the intact cartilage of the opposite, nonoperated ... magnitude (the maximum magnitude of the measurement area divided by that of the intact cartilage of the nonoperated knee; %MM) is used as a quantitative index of cartilage regeneration conditions according ... for detecting regenerationof the cartilage surface in tissue engineering Further studies using lowfrequency ultrasound may provide a better assessment of the deeper layers in tissue- engineered...
... delivery vehicles to tumor tissues [20,24] The physiological significance of EPCs is varied and is of relevance in both normal and tumor tissueregeneration Clinical exploitation of these cells is critically ... recruitment of EPCs into the circulation Circulating EPCs have a wide array of functions in tissue regeneration, tissue remodelling and cancer progression In tumors and ischemic tissues EPCs ... serve as a sensor of tumor initiation Further, tagging of EPCs may allow tracing of their mobilization and homing to tumor tissues aiding in specific, targeted early detection of tumor growth,...
... goal of periodontal therapy is to control periodontal tissue inflammation and to produce predictable regenerationof periodontium lost as a result of periodontal disease In order to promote the regeneration ... promote the regenerationof the periodontium the appropriate positioning of cells capable of synthesizing collagen, cementum and bone is required The procedure of guided tissueregeneration (GTR) was ... principle of guided tissueregeneration (GTR) is utilized to exlude epithelium from the root surfaces and to promote selective repopulation of the root surface by multipotential cells The main goal of...
... ENCAPSULATION OF POLYMERIC MICROSPHERES AS SCAFFOLD FOR LIVER TISSUEREGENERATION BY XINHAO ZHU (M Eng., B Eng., TsingHua University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ... limitations of the current therapies encourage researchers to find alternatives, such as regenerationof failed organs The science oftissue engineering, which combines the disciplines of engineering ... so important for the success oftissue engineering that finding an appropriate scaffold for specific tissueregeneration has always been one of the primary tasks for tissue engineers Therefore,...
... shows the contribution of this strategy to the development of plants with biofarming potential in the frame of a high demand of natural and ecologically accepted sources of renewable compounds ... export of the excess of reducing power via the malate valve, and productive consumption of the surplus of NADPH by the Calvin cycle Finally, as is the case with iron deficiency, the extent of protection ... the evolution of vascular plants The case of Fld and Cyt c6 shows that reintroduction of these genes in the proper subcellular compartment of model and crop plants restored some of the selective...
... aggregation in the presence of a mixture of annexins of different subtypes The profile of liposome aggregation was simply the sum of the results obtained with a single subtype of annexin, suggesting ... above, various pairing of S100 and annexins may be an intrinsic and conventional mechanism of the S-100 annexin system to function in a variety of tissues The participants of these complexes are ... animal model of Parkinsonism [45] The identification of the targets of the S100A10–annexin A2 complex (see above) led to the suggestion that this complex functions as a guiding molecule of channels...
... formation of an alkaline phosphatase frame-shift mutant Hypophosphatasia is an inborn error of metabolism characterized by defective mineralization of hard tissues and reduced levels oftissue nonspecific ... assembly of TNSALP in the endoplasmic reticulum (ER), resulting in the loss of functional TNSALP from the cell surface [10–14] Deletion of T at position 1559 of the cDNA [TNSALP (1559delT)] of the ... concerted action of nucleoside triphosphate pyrophosphohydolase and TNSALP regulates local concentration of inorganic pyrophosphate at the site of mineralization, which, as a poison of hydroxyapatite...
... artefact of recombinant production because a similar low rate of substitution of recombinant perlecan domain V correlated well with a comparable low rate of modi®cation of two tissue forms of perlecan ... levels of laminin c1 chains in EDTA/detergent extracts of various mouse tissues The content of b1 chains in these extracts exceeded the content of b2 by a factor of 5±20 The relative amounts of b2 ... 20%) of such inhibition assays [36], in most cases in good agreement with the sum of b1 and b2 chains It served therefore as an internal control for the quality of the data Tissue extracts of mice...
... defective osteogenesis with various degree of failure in mineralization of hard tissues such as bone and tooth [1–3] Various mutations in the human tissue- nonspecific alkaline phosphatase (TNSALP, ... forms of the wild-type, which migrates on the SDS gel as the 66 kDa or 80 kDa form To address the question of whether the replacement of arginine at position 433 affects the catalytic function of ... amount of the 80 kDa noncross-linked form, over a wide range of expression conditions (Fig 4) Induction of TNSALP(R433C) was found to be regulated tightly, as no band was observed in the absence of...
... Scientific Biologyof Wastewater Treatment (New Edition) Nature of Wastewater 23 population of a city the size of Manchester will produce an organic load equivalent to the human population of a small ... Scientific Biologyof Wastewater Treatment (New Edition) Introduction Table 1.3 EU Directives concerning inland waters by year of introduction 1973 Council Directive on the approximation of the laws of ... bwt January 19, 2004 14:33 World Scientific Biologyof Wastewater Treatment (New Edition) Nature of Wastewater 15 that are the major cause of pollution of receiving waters in Britain and Ireland...
... levels of crabp1b transcripts may be below the level of sensi3566 tivity of detection by the technique oftissue section in situ hybridization Discussion The differentiation and development of primary ... cord and ventral part of anterior myotomes (Fig 5H,J,L) Tissue- specific distribution of crabp1a and crabp1b mRNA in adult zebrafish Fig Comparison of the syntenic relationship of the zebrafish crabp1 ... single product corresponding to the position of the 7-methyl G cap of the mature crabp1a mRNA (data not shown) Alignment of the nucleotide sequence of the cloned 5¢-RLMRACE product with the genomic...
... regulation of a variety of cellular processes, including pericellular proteolysis, cell–cell or cell–ECM adhesion, and regulation of membrane architecture [13–16] One of the important functions of extracellular ... expression of annexin II protein Suppression of annexin II expression also suppressed binding of exogenous tPA to the matrilysin-treated cells, as well as the release of cleaved annexin II All of these ... preparation showed a purity of 80–90% for the total annexin II as judged by SDS/PAGE Cleavage of annexin II by MMPs and determination of N-terminal amino acid sequence The proforms of matrilysin and other...
... Other reviews of nanotechnology applications for the specific regenerationof tissues can be found [15,76,86—92] Nanotechnology approaches for the regenerationof other types of tissues (such ... of nanomaterials for numerous tissue engineering applications The promise of nanomaterials for neural tissue engineering applications In addition to aiding in orthopedic and vascular tissue regeneration, ... Moreover, cartilage is a low regenerative tissue composed of a small Nanotechnology and nanomaterials: Promises for improved tissueregeneration percentage of chondrocytes but dense nanostructured...
... Over 80 Years of Research Expertise Over 80 Years of Research Expertise Leveraging the power of genetics in the search for cures to human disease search for cures to human disease Nonprofit research institute founded in ... Resorption of fetuses of fetuses – Cannibalism of litters • Health status Health status • Seasonal effects Seasonal variation in inbred mice Seasonal variation in inbred mice Month of the year ... Common inbred strains (C57BL/6J, BALB/cJ, DBA/2J) support development/collection of specialty strains and other valuable development/collection of specialty strains and other valuable community research resources ...
... characteristics of water quality in the estuary of Strymon River J Mar Environ Engin 7: 231–239 Hutchings J.A 2002: Life histories of fish In: Hart P.J.B & Reynolds J.D (eds.), Handbook of fish biology ... of 50 oocytes per female was calculated as the mean value of minimum and maximum diameter microscopic measurements Relative fecundity (RelF) was considered as the number of oocytes per unit of ... total length of males ranged between 2.5 and 6.0 cm and that of females between 2.8 and 5.7 cm, while that of unsexed individuals ranged between 1.2 and 2.9 cm Overall, 346 (60.59%) out of the 571...
... properly cited 4 Evolution of the Molecular Biologyof Brain Tumors and the Therapeutic Implications high grade gliomas The structure and compounds of the ECM of the brain tissue have many specific ... passage of a wide variety of anticancer agents The high incidence of recur‐ rence and poor prognosis of malignant gliomas compel the development of more powerful anti-cancer treatments Action of alkylating ... proliferation, migration, reorganization of ECM and tube formation The advent of molecular studies allowed a new evaluation of the biologyof gliomas with, a level of precision that promises interesting...
... and Björn Malmqvist The Biologyof Mangroves Peter F Hogarth The Biologyof Soft Shores and Estuaries Colin Little The Biologyof the Deep Ocean Peter Herring The Biologyof Lakes and Ponds, Second ... habitat The Biologyof Rocky Shores Colin Little and F A Kitching The Biologyof Polar Habitats G E Fogg The Biologyof Lakes and Ponds Christer Brönmark and Lars-Anders Hansson The Biologyof Streams ... important groups of organisms within each of the body size categories, namely microfauna, mesofauna, and macrofauna Microfauna The two most abundant groups of microfauna are the protozoa and nematodes...