bioactive foods and extracts in prostate cancer prevention
Bioactive Foods and Extracts ppt
... daily intake of glucobrassicin and neoglucobrassicin (the two main dietary indole glucosinolates) was 22.5 mg per day in the United Kingdom 5.5 mg in Denmark, and 2.8 mg in Finland (IARC, 2004) In ... II Bioactive Foods and Supplements in Cancer Prevention Chapter Bioactive Foods in Cancer Prevention 143 Rakesh Sharma and Jose Katz Chapter 10 Curcumin-Mediated Cellular Responses in ... Bioactive Foods and Extracts Cancer Treatment and Prevention Bioactive Foods and Extracts Cancer Treatment and Prevention Edited by Ronald Ross Watson...
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báo cáo hóa học:" Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer" pptx
... liver and pancreas by immunohistochemical staining In contrast, PSA was stained in both prostate cancer tissue and non-cancerous tissue (Figure 2C) These data indicated that AMACR had a mostly cancer- specific ... Immunostaining of prostate cancer tissue with antibodies against AMACR and PSA Immunostaining of prostate cancer tissue with antibodies against AMACR and PSA Surgically resected prostate cancer tissue ... was detected in three prostate cancer cell lines (LNCaP, DU145 and PC-3) C Expression of AMACR in cancer tissues and noncancerous tissues from surgical specimens of two prostate cancer cases...
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Báo cáo khoa học: "The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation" pot
... inhibitors of the PI3K/Akt pathway in prostate cancer cells Combined effects of ErPC3 and ionizing radiation in prostate cancer cell lines Up to now our data revealed that ErPC3 is a potent inhibitor ... ErPC3, in preclinical and clinical investigations is based on their ability to induce apoptosis in tumor cells and their ability to increase cytotoxic efficacy of chemotherapy and radiotherapy in ... inactivated in a variety of solid human tumors, including prostate cancer Increased levels of PIP3 trigger the recruitment of phosphatidylinositide-dependent serine/threonine kinase (PDK1) and Akt...
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Báo cáo khoa học: "Early prediction of response to radiotherapy and androgen-deprivation therapy in prostate cancer by repeated functional MRI: a preclinical study" pptx
... training, testing and validating the network showed curve flattening after a few training epochs, this indicated that no overtraining occurred However, if such a model is to be applied on clinical ... preclinical study in prostate cancer xenografts, and suggest that the combination of functional MRI parameters, in addition to standard clinical parameters, increases the power of predicting therapeutic ... prediction, wherein different pre-treatment and early in- treatment functional imaging parameters may be combined with standard clinical parameters in order to increase the prediction of how individual...
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Báo cáo khoa học: "The evolution of rectal and urinary toxicity and immune response in prostate cancer patients treated with two three-dimensional conformal radiotherapy techniques" ppt
... becoming one of the most significant issues in treatment decision-making, in general, and more so in prostate cancer [1] Thus late rectal and urinary damage became a major concern in prostate cancer; ... radiotherapy-irradiation of prostate, seminal vesicles, and lymph nodes followed by a prostate boost (116 patients, 59%); and prostate- only (PO) radiotherapy-irradiation of prostate and seminal vesicles (81 ... volume and critical normal structure definition Treatment planning and irradiation were performed with the patients in supine position (using knee and ankle supports) with an emptied rectum and...
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Báo cáo khoa học: "In vitro studies on the modification of low-dose hyper-radiosensitivity in prostate cancer cells by incubation with genistein and estradiol" pot
... several protein tyrosine- and histidine kinases [810], and inhibits topoisomerase I and II [11] These effects result in alterations of several intracellular and extracellular pathways including cell ... radiosensitivity in the androgen independent PC cell line PC-3 has been demonstrated in vitro and in vivo [26,27] Our study analyzes the interactions of irradiation and genistein or estradiol incubation in androgen ... anti -prostate cancer activity in vitro and in vivo Clin Cancer Res 2004, 10:5282-5292 Ouchi H, Ishiguro H, Ikeda N, Hori M, Kubota Y, Uemura H: Genistein induces cell growth inhibition in prostate...
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Báo cáo khoa học: "Acute and late toxicity in prostate cancer patients treated by dose escalated intensity modulated radiation therapy and organ tracking" pps
... Kemmerling L, Born EJ, Mini R, Greiner RH, Aebersold DM: Daily organ tracking in intensitymodulated radiotherapy of prostate cancer using an electronic portal imaging device with a dose saving acquisition ... abdomen and pelvis and a total-body bone scan When clinically indicated a chest x-ray and/ or thoracic CT was performed Based on these examinations clinical staging was defined according to the ... summarized in Table Incidence of single symptoms (diarrhea, rectal pain, rectal bleeding) as well as the highest toxicity occurred in a given patient concluding all single symptoms but counting only...
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Báo cáo khoa học: " Potentials of on-line repositioning based on implanted fiducial markers and electronic portal imaging in prostate cancer radiotherapy" docx
... 23 patients) in Table and the mean standard deviations (mean random error) in Table Then, we determined means and standard deviations from control EPIs for each patient resulting in the same error ... values10%variability, prostate line), format, Measured deviations in and Measured deviations in LR, SI and AP directions in a box plot format, showing the mean values (black squares), the median values (lines in ... issue indicate that a 3mm planning target margin is in most cases sufficient to account for intrafractional motion [39] Both uncertainties, setup error and target motion can be split into random and...
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báo cáo khoa học: " XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells" docx
... somatostatin and Octreotide in prostate cancer cell lines To examine the regulatory effects of somatostatin and Octreotide on XAF1 mRNA and protein expression, prostate cancer cell lines (LNCaP, ... somatostatin indicates a promising strategy for prostate cancer therapy Materials and methods Cell lines and cell culture A human prostate epithelial cell line (RWPE-1) and prostate cancer cell lines ... in prostate cancer cell lines We found that somatostatin and Octreotide up-regulated XAF1 mRNA and protein expression in prostate cancer cell lines The enhanced XAF1 expression by somatostatin...
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Báo cáo y học: "Identification of candidate predictive and surrogate molecular markers for dasatinib in prostate cancer: rationale for patient selection and efficacy monitoring" doc
... targeted therapeutics for prostate cancer candidate predictor of efficacy in both prostate and breast cancer Finally, the observed sensitivity to dasatinib of prostate cancer cell lines with expression ... model in prostate cell lines and tumors Expression pattern of a five-gene model in prostate cell lines and tumors (a) Hierarchical clustering of five genes, AR, PSA, CK5, uPA, and EphA2, in prostate ... JS: RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo...
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CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF TRACE AMOUNT OF SEX HORMONE RECEPTOR ACTIVE COMPOUNDS IN PROSTATE CANCER RELATED BIOLOGICAL SAMPLES
... Occurrence of Prostate Cancer (PCa) in Men 2-3 1.2 Prostate and its Importance 1.3 Signs & Symptoms and Detection of Prostate Cancers 1.4 Treatment Options for Prostate Cancer 1.4.1 Hormone or Androgen ... using non-androgenic ligands such as estrogens for activation also seemed to play a role in maintaining proliferation of these cells AKR1C3 is the critical enzyme to synthesise T and DHT in prostate ... and T6 (p-value < 0.05) and T5 and T6 (p-value < 0.05), where under T6, which contains 50 µM Dimethoxycurcumin can induce a significant increase in intracellular 3β-Diol, a selective ERβ ligand...
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Tài liệu FACTS AND FIGURES CAUSES OF CANCER PREVENTION EARLY DETECTION CURE AND CARE CONTACTS docx
... Organization and the International Union Against Cancer be liable for damages arising from its use Printed in Switzerland Design: Helena Zanelli Création International Union Against Cancer Campaigns ... lives Cancer is potentially the most preventable and most curable of the major life-threatening diseases facing humankind By applying existing knowledge and promoting evidence-based actions in cancer ... Developing countries Transition PREVENTION 14 15 PREVENTION In many countries, people are more and exercising less an active lifestyle In high income countries, people are eating more and exercising...
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American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention doc
... Moderate intensity Exercise and leisure Vigorous intensity Walking, dancing, leisurely bicycling, ice and roller skating, horseback riding, canoeing, yoga Jogging or running, fast bicycling, circuit ... meat-containing diets Vitamin A Does vitamin A lower cancer risk? Vitamin A (retinol) is obtained from foods in ways: it can be taken in as vitamin A from animal food sources, or it can be made in the ... your intake of refined carbohydrate foods, including pastries, candy, sugarsweetened breakfast cereals, and other high-sugar foods Studies showing that higher vegetable and fruit intake reduces cancer...
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Progress in Cervical Cancer Prevention: The CCA Report Card pot
... credited with making cervical cancer a national priority, introducing visual inspection with acetic acid (VIA) and expanding cryotherapy, and improving training for the next generation of clinicians ... from 25 cancers in 1990 Int J Cancer Sept 1999;83(1):18-29 • Singh S, Darroch JE, Ashford LS, Vlassoff M Adding It Up: The Costs and Benefits of Investing in Family Planning and Maternal and Newborn ... vaccine introduction in low- and middle-income settings For example, beginning in 2006, PATH, an international NGO, established demonstration projects in India, Peru, Uganda and Vietnam to assess...
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ADVANCES IN PROSTATE CANCER docx
... of all prostate cancer cases The risk of getting prostate cancer increases nearly exponentially with increasing age This makes prostate cancer one of the most distinctive cancers in aging popu‐ ... Integrins in Prostate Cancer Invasion and Metastasis 619 Paulynn Chin Suyin, Joanne Louise Dickinson and Adele Frances Holloway Chapter 26 The Role of E-Cadherin-Catenin Complex in Prostate Cancer ... Yeong-Min Park and Soon-Cheol Ahn Contents Chapter 16 Natural Compounds, Antioxidant and Antiandrogens in the Prevention of Prostate Cancer: In vivo Evidences from Murine Models and Human Clinical...
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Báo cáo khoa học: Altered expression of tumor protein D52 regulates apoptosis and migration of prostate cancer cells potx
... survival and motility [37] Usually, integrins avb3 and avb5 are involved in cell migration and attachment to the extracellular matrix proteins: vitronectin, fibronectin, fibrinogen, laminin, osteopontin, ... Tumor protein D52 in prostate cancer R Ummanni et al Results A protein profiling study on prostate biopsies identified differentially expressed proteins in cancer containing several proteins that ... both avb3 integrins in LNCaP cells In addition to these reports, Putz et al [42] reported four prostate cancer cell lines that were derived from bone marrow expressing av and b3 integrin subunits...
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báo cáo hóa học:" Can urinary exosomes act as treatment response markers in prostate cancer?" ppt
... produced by LNCaP -prostate cancer cell line Prostate cancer cell lines (LNCaP and DU145), as indicated, were maintained in culture as a source of positive-control prostate cancer exosomes (for ... loading Bands for prostate- derived proteins PSA or PSMA were evident in patients (p1, p7, p8, p9, p10), indicating that at least some of the exosomes present in the urine were of prostate origin ... advances are being made in understanding the biology underlying this disease, and in many respects in its treatment, there remains a need for better tools for PCa diagnosis and monitoring Disease-related...
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Báo cáo hóa học: " Copy number and gene expression differences between African American and Caucasian American prostate cancer" docx
... differentially affected AA and CA tumors in two independent patient cohorts Of note, 14q32 was gained in CA patients in the initial cohort but gained in AA patients in the validation cohort This ... design and interpretation of data WG was involved in the study design and supervised all experiments PL and IO served as the principal investigators All authors read and approved the final manuscript ... AL: Racial and ethnic differences in advanced-stage prostate cancer: the Prostate Cancer Outcomes Study J Natl Cancer Inst 2001, 93:388-395 Albano JD, Ward E, Jemal A, Anderson R, Cokkinides VE,...
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