bicarbonate serum and antibiotics
Tài liệu Báo cáo khoa học: Treatment of neutral glycosphingolipid lysosomal storage diseases via inhibition of the ABC drug transporter, MDR1 Cyclosporin A can lower serum and liver globotriaosyl ceramide levels in the Fabry mouse model doc
... ng standard Gb3 and was able to detect > ng Gb3 per lL serum sample Gb3 in the serum of wildtype mice was below the background of this assay MDR1 inhibition and GSL storage disease ERT and CsA ... the serum Gb3 levels [9] and the effect of a maintenance dosing of CsA on the recovery of serum Gb3 levels after termination of ERT was determined ERT is an effective means of eliminating serum ... 0.028) The recovery of serum Gb3 post ERT was found to be, to some extent, variable and some mice within both the control and treated groups did not recover detectable serum Gb3 by the 9-week...
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Báo cáo khoa học: Abstract P1 – FEBS Datta Plenary Lectureship Award P1-001 Peptide bond formation, cotranslational folding and antibiotics synergism docx
... chromosome organization and genome stability The implications of epigenetic research for human biology and disease, including stem cells, cancer and aging are far-reaching and will form a modern ... lacking both DAP12 and FcRc DAP12–/– FcRc–/– double and Syk–/– single mutant bone marrow cells failed to differentiate into mature osteoclasts and did not resorb bone DAP12 and FcRc were constitutively ... genomic DNA is highly folded and compacted with histone and nonhistone proteins in a dynamic polymer called chromatin The discoveries that nucleosome remodelling machines and histonemodifying enzymes...
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báo cáo hóa học:" Serum and follicular anti-Mullerian hormone levels in women with polycystic ovary syndrome (PCOS) under metformin" pot
... found between serum AMH levels and both follicle count and androgen levels [9] These correlations were successively confirmed [12], and a further relationship between AMH levels and insulin resistance ... Met-anov and Met-ov groups was observed at baseline and after metformin with regards to the serum levels of SHBG, fasting insulin, GIR, HOMA, and AMH before treatment (Table 1) In both Met-anov and ... testosterone (T), androstenedione (A), dehydroepiandrosterone sulfate (DHEAS), and sex-hormone binding globulin (SHBG)], and metabolic evaluation, including evaluation of fasting glucose and insulin...
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Báo cáo y học: "Biomarker profiles in serum and saliva of experimental Sjögren''''s syndrome: associations with specific autoimmune manifestations" ppt
... respectively Thirty-six and 54 of the biomarkers have not yet been analyzed in serum and saliva obtained from patients with SS, and neither have 70 of the analytes in serum and 62 biomarkers in ... profiles from serum and saliva A bead-based multiplex sandwich immunofluorescence assay was used to generate multi-analyte profiles (MAPs) from serum and saliva from the 12 nondiabetic NOD and 12 Balb/ ... adhesion molecule (VCAM)-1 and IgA In saliva, C-C chemokine ligand/C chemokine ligand Sa-C-2 (eotaxin and macrophage-derived chemokine [MDC]) and cytokine Sa-C-3 (CD40 and CD40L [IL-18 borderline])...
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Báo cáo y học: "Duodenal enteroglucagonoma revealed by differential comparison of serum and tissue glucagon reactivity with Siemens'''' Double Glucagon Antibody and DakoCytomation''''s Polyclonal Rabbit Anti-Human Glucagon: a case report" ppsx
... aspiration, disseminated candidiasis with candidal sepsis, wound infection, disseminated varicella, atrial fibrillation, acute renal failure and a subhepatic intra-abdominal candidal abscess Discharge ... this article as: Vanderlan et al., Duodenal enteroglucagonoma revealed by differential comparison of serum and tissue glucagon reactivity with Siemens' Double Glucagon Antibody and DakoCytomation's ... hospital His serum potassium remained low despite all replacement efforts Hypoalbuminemia worsened to 1.6 gm/dL Serum glucagon was measured using Siemens' Double Glucagon Antibody and found to...
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Báo cáo y học: "A simple hepatic cyst with elevated serum and cyst fluid CA19-9 levels: a case report" pps
... intracystic instillation of minocycline before and Changes2in serum and cyst fluid CA19-9 levelshydrochloride Changes in serum and cyst fluid CA19-9 levels before and after the intracystic instillation ... that serum CA19-9 levels in serum CA19-9 (U/ml) patients with cholelithiasis complicated by cholangitis frequently showed markedly high values, and serum CA19-9 levels were rapidly decreased and ... stroma: expressions of CA 19-9 and carcinoembryonic antigen in serum and cystic fluid J Gastroenterol 1996, 31:732-736 Horsmans Y, Laka A, Gigot JF, Geubel AP: Serum and cystic fluid CA 19-9 determinations...
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Báo cáo y học: "Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254)" ppt
... baseline and follow up time points and between serum and synovial fluid values Non parametric Spearman Rank correlations (rs) were performed to determine correlations between synovial fluid and serum ... 0.012), COMP (P = 0.0001) and MMP-3 (P = 0.0001) The biggest differences between synovial fluid and serum were observed for MMP-3 and COMP with fold differences of 738.8 and 21.2 respectively Smaller ... Biomarker concentrations at baseline and follow-up in serum and synovial fluid after acute knee injury Synovial Fluid Levels Biomarker Baseline Mean ±SD Serum Levels Serum vs Synovial Fluid Follow...
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Báo cáo y học: " The predictive role of serum and bronchoalveolar lavage cytokines and adhesion molecules for acute respiratory distress syndrome development and outcome" pptx
... NCI-H441, and human fetal lung explants H441 cells resemble bronchiolar epithelial Clara cells in phenotype and produce both SP-A and SP-B mRNA and protein [14] The hormonal regulation of SP-A and ... LY294002, rapamycin and PD98059 were reconstituted in dimethyl sulphoxide as mM, 50 mM, 50 µM and 10 mM stock solutions, respectively, and stored at -80°C in aliquots Insulin causes a timeand dose-dependent ... vehicle or insulin (2.5 µg/ml) for an additional 1, 4, and 24 hours The cells were then rinsed and trypsinized, and nuclei from control and treated cells were harvested The transcription elongation...
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Báo cáo y học: " The predictive role of serum and bronchoalveolar lavage cytokines and adhesion molecules for acute respiratory distress syndrome development and outcome" doc
... their serum (P < 0.01 to P < 0.0001) (Table 5) Predictive serum and BALF levels of all studied molecules for surviving are shown in Tables and In contrast to BALF values, serum levels of IL-1 and ... values and the range in BALF and serum of the studied mediators in survivors and non-survivors in all categories are shown in Table All studied mediators were found at higher levels in the serum ... predictive value, sensitivity and specificity for surviving in all groups In a multivariate analysis model adjusting for age and severity we found that serum IL-1 (P = 0,002) and serum ICAM-1 (P = 0,009)...
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Báo cáo y học: "Matrix-metalloproteinase-2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis" potx
... MODS and MOF patients The time points for the comparisons were on day and for blister fluid samples and days 1, 4, 6, and 10 for serum samples The serum and blister fluid MMP-levels of MODS and ... detected in the serum samples in patients and controls and the 82 kDa MMP-9 could be detected only in few samples (3 on day 1; on day 4; on days 6, and 10; and at and months) At three and six months ... MMP-8 Statistical analysis Serum and blister fluid levels of MMP-8, MMP-9 (92 kDa and 82 kDa forms), and MMP-2 (72 kDa and 62 kDa forms) were compared between non-surviving and surviving patients...
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Relationship of intravenous sodium bicarbonate infusions and cerebral intraventricular hemorrhage j pediatr 1978; 93834
... Table II Sodium bicarbonate therapy and IVH IVH[NolVH ITotal >8mEq sodium bicarbonate/ kg/24 hr 0.20) Serum sodium concentrations are given in Table III Twelve infants (seven with IVH and five with no IVH) died prior to 12 hours of age and did not have serum sodium determinations...
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Báo cáo y học: "Long Term Persistence of IgE Anti-Influenza Virus Antibodies in Pediatric and Adult Serum Post Vaccination with Influenza Virus Vaccine"
... presence and persistence of IgG and IgE anti-influenza antibodies in the serum from those with normal and ele- 243 vated levels of IgE are understandable Our findings appear to be of importance and ... RESULTS Characteristics of Study Subjects Serum IgE levels and IgE and IgG anti-Influenza virus antibodies were studied in children (N=3) (m/f 14-16 y/o) and adults (N=3) (m/f, 41-49 y/o) approaching ... Total serum IgE levels were both normal and elevated in adults and children vaccinated with Influenza virus Children with no history of either Influenza virus infection or vaccination had serum...
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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... Sample pretreatments and proteomic analysis in the proteomic profiling analysis, the serum samples from the diseased and control groups were randomized, and blinded to investigators Serum samples were ... of Serum Samples in Patients with CRC and Healthy Controls The protein profile of the serum samples from the 98 patients with CRC and the 80 healthy controls were extracted by magnetic beads and ... and had the informed consent of the patients and volunteers The patients and serum samples were then divided into two groups: the ‘‘training’’ set and the blinded ‘‘test’’ set (Table 2).The blood...
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Báo cáo y học: "Comparative study of serum Na+ and K+ levels in senile cataract patients and normal individuals"
... range of patients and controls were 44-85 year and 43-86 year respectively Table shows serum Na+, K+ of case and control groups, with a significant difference in serum + Na of case and control ones ... senile cataract (79 female, 76 male) and the control one consisted of 155 of cases’ close relatives (79 female, 76 male) Mean age and standard deviation of patients and control group were 61.96±14.5, ... control group and sent to the laboratory Serum Na+, K+ levels were measured with flam photometry method by the aid of SEAC model FLP20, Italy Outcoming data was assessed by spss 11 software and mean...
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Tài liệu Serum cytokine profiles in healthy young and elderly population assessed using multiplexed bead-based immunoassays doc
... albumin, serum blood urea nitrogen (BUN), and serum creatinine levels (Table 1) Comparison of the serum concentrations of 22 cytokines, chemokines, and growth factors demonstrated that sCD40L and ... increases in the serum concentrations of sCD40L and TGF-a and significant decreases in the serum concentrations of G-CSF, GM-CSF, and MCP-1 Future studies will focus on understanding the significance ... interpretation and in the writing HOK and HSK performed the analysis of the data and drafted the manuscript JCY and ECS participated in the design of the study and performed the statistical analysis and...
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Tài liệu Báo cáo khoa học: Expression and secretion of interleukin-1b, tumour necrosis factor-a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem cells Implications for their paracrine roles ppt
... presence and absence of 0.1 lM angiotensin II and IL-10 BrdU incorporation into cardiac fibroblast under normal 10% fetal bovine serum or serum- free culture conditions IL-10 also decreased type I and ... NF-jB-dependent IL-1b and TNF-a transcription Because transcription of IL-1b and TNF-a can be augmented in MSCs by hypoxia [5], and because the molecular masss of IL-1b and TNF-a are both 17 ... III and a-smooth muscle actin (a-SMA) in cardiac fibroblasts in the presence and absence of IL-10 *P < 0.05 and **P < 0.01 versus Cont group (D) Representative western blots for collagen I and...
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Tài liệu Báo cáo khoa học: Allosteric modulation of myristate and Mn(III)heme binding to human serum albumin Optical and NMR spectroscopy characterization pptx
... transport of lipophilic compounds and drugs and of medium and long chain fatty acids; among them, myristic acid is a stereotypic ligand to investigate fatty acid binding and transport properties of ... of membrane lipids, hormones and second messengers, and serve as an important source of metabolic energy Although the binding of fatty acids to human and bovine serum albumin has been thoroughly ... sites, and at least three further low affinity sites have been envisaged NMR studies on tryptic and peptic fragments of bovine serum albumin have localized two high affinity sites in domain III and...
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Tài liệu Báo cáo Y học: Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin doc
... Tables and thus present only the novel data: protonation constants for DAHKam and VIHN, and stability constants (log a values) of Cu(II)-VIHN, Cu-DAHKam and Ni-DAHKam systems The parameters of CD and ... Ni(II) and Cu(II) complexes of peptides at I = 0.1 M (KNO3) and 25 C Standard deviations on the last digits are given in parentheses EPR The X-band EPR spectra of Cu(II) complexes of VIHN and DAHKam ... considered Comparison of Cu(II) and Ni(II) binding between model peptides and albumins Afnity for Ni(II) at site I can be compared between albumins on one hand and DAHam and DAHKam on the other Much...
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Tài liệu Báo cáo Y học: Transactivation domains are not functionally conserved between vertebrate and invertebrate serum response factors potx
... structure and regulation could be conserved but SRF expression patterns and SRF-dependent promoters could have changed during evolution Further understanding of the evolution of SRF and SRFdependent ... supplemented with 10% fetal bovine serum and mM glutamine Embryonic fibroblastoid cells NIH3T3 were cultured in DMEM supplemented with 10% neonatal bovine serum and mM glutamine Cells were transfected ... promoters, c-fos and Act403, and had no significant effects on the weaker CA and Act403mut promoters The activity of the SRFs from these three species was also tested for c-fos and CA promoters...
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Identification of serum proteomic biomarkers for early porcine reproductive and respiratory syndrome (PRRS) infection pptx
... = pH4, F5 = pH3, and F6 = organic solvent The fractions F1, F4, and F6 were analyzed on the three surfaces CM10, IMAC30, and H50 at both low and high focus masses Fractions F2 and F3 were excluded ... LMW and low abundance region of the serum proteome, and specific protein fragments of the serum peptidome have been shown to contain a rich source of disease-specific diagnostic information and ... fractions F1, F4, and F6 on the surfaces CM10, IMAC30, and H50 showed generally good signal intensities and low coefficient of variation (CV) values (< 30%) in both the discovery and validation...
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