... Nevoid basalcellcarcinomasyndrome Multiple basalcell carcinomas of the palms after radiation therapy Arch Dermatol 116: 1159-1163 [25] Howell, J.B (1984) Nevoid basalcellcarcinomasyndrome ... development of basalcell carcinomas (BCC) While it has not been fully clarified which primary cell gives rise to basalcell carcinomas it is supposed that BCCs arise from interfollicular basal cells, ... the Development of BasalCellCarcinoma 71 Eijun Itakura Chapter Metastatic BasalCellCarcinoma Anthony Vu and Donald Jr Laub Chapter Genomics of Basal and Squamous Cell Carcinomas Venura Samarasinghe,...
... Nevoid basalcellcarcinomasyndrome Multiple basalcell carcinomas of the palms after radiation therapy Arch Dermatol 116: 1159-1163 [25] Howell, J.B (1984) Nevoid basalcellcarcinomasyndrome ... development of basalcell carcinomas (BCC) While it has not been fully clarified which primary cell gives rise to basalcell carcinomas it is supposed that BCCs arise from interfollicular basal cells, ... the Development of BasalCellCarcinoma 71 Eijun Itakura Chapter Metastatic BasalCellCarcinoma Anthony Vu and Donald Jr Laub Chapter Genomics of Basal and Squamous Cell Carcinomas Venura Samarasinghe,...
... development of certain cutaneous squamous cell carcinomas However, only few reports contain data on basalcellcarcinoma (BCC) The HPVs interact with many cellular proteins altering their function ... was detected in 30–90% of actinic keratosis and squamous cell carcinomas of non-EV patients (14,15) but few data exist on basalcellcarcinoma (BCC), the commonest NMSC Our study aimed to determine ... Epidermodysplasia Verruciformis (EV); Non-melanoma skin cancers (NMSC); Squamous cellcarcinoma (SCC); Basalcellcarcinoma (BCC) Competing interests The authors state no conflict of interest Authors'...
... chromogranin and neural cell adhesion molecules (CD56) [11] The association of basalcellcarcinoma and neuroendocrine carcinoma of the skin, also called Merkel cellcarcinoma (MCC), is a rare ... cervical carcinoma and a basalcellcarcinoma but in a metachronous setting [6] Human papilloma virus (HPV) infection has a wellestablished role in the carcinogenesis of cervical squamous cell carcinomas, ... al.: Triple malignancy in a single patient including a cervical carcinoma, a basalcellcarcinoma of the skin and a neuroendocrine carcinoma from an unknown primary site: A case report and review...
... Introduction Nevoid basalcellcarcinomasyndrome (NBCC; also known as Gorlin syndrome; MIM #109400) is a rare autosomal dominant disorder characterized by numerous basalcell carcinomas, odontogenic ... Hum Mutat 2003, 21(6):577-581 Abbreviations BFH: basaloid follicular hamartoma; CNS: central nervous system; NBCC: nevoid basalcellcarcinoma syndrome; PTCH: patched homolog (Drosophila); Shh: ... variable cell thickness Keratinization appeared to be abrupt with lack of a granular cell layer The presence of multiple jaw cysts devoid of a granular layer raised the suspicion of nevoid basal cell...
... odynophagia, and progressive weight loss The two predominant histological subtypes are adenocarcinoma and squamous cell carcinoma, and treatment depends on the location of the primary tumor, the disease ... squamous cellcarcinoma of the esophagus J Clin Oncol 1999; 17: 2915-21 Kaneko K, Ito H, Konishi K, et al Definitive chemoradiotherapy for patients with malignant stricture due to T3 or T4 squamous cell ... = 51/5 Race Japanese Performance status 0/1/2/unknown = 28/22/4/2 Histological type squamous cellcarcinoma Differentiation well/moderate/poor/unknown = 8/31/9/8 TNM score T1/T2/T3/T4 = 17/6/21/12...
... Cholinesterases in renal carcinomas E Munoz-Delgado et al ˜ Introduction Renal cell carcinomas (RCCs), which account for 2% of adult malignancies, affect ... endoplasmic reticulum of mesangial cells and for butyrylcholinesterase in the reticulum of endothelial cells [32] Thus, it is likely that epithelial, mesangial and endothelial cells can all contribute ... staging system of renal cellcarcinoma A Swiss experience with 588 tumors Cancer 89, 604–614 Hansel DE (2006) Genetic alterations and histopathologic findings in familial renal carcinoma Histol Histopathol...
... and added to the cells After 24, 48 and 72 h, CM were collected and the cells were processed further (total RNA and ⁄ or cell lysates) Cell survival ⁄ proliferation assay The cells were seeded ... and cell lysates (CM and L, respectively) were collected and TSP1 was detected by western blotting Note the low TSP1 secretion and higher intracellular levels in RCC cells (F) HNK and P769 cells ... availability in HNK and RCC cells We measured calcium uptake by the cells stimulated by VEGF: 10 ngÆmL)1 VEGF caused no measurable intake of Ca2+in RCC cells, whereas HNK cells developed a robust...
... Clear cell renal cellcarcinoma This is the most common form of renal cellcarcinoma About out of 10 people with renal cellcarcinoma have this kind of cancer When seen under a microscope, the cells ... filters blood much like a real kidney would Renal cellcarcinoma Renal cellcarcinoma (RCC), also known as renal cell cancer or renal cell adenocarcinoma, is by far the most common type of kidney ... transitional cell carcinomas, Wilms tumors, and renal sarcomas Transitional cellcarcinoma Of every 100 cancers in the kidney, about to 10 are transitional cell carcinomas, also known as urothelial carcinomas...
... Soluble E-cadherin has been shown to disrupt cellcell adhesion in cultured epithelial cells [13] Transfection of E-cadherin cDNA into invasive carcinoma cells leads to a significant reduction of ... squamous cellcarcinoma 120 kDa 120 kDa 50 kDa 50 kDa Beta akt C M Fig Truncated P-cadherin in cell lysates and supernatants of OSCC cell lines (A) Western blot analysis of five OSCC cell lines ... cell lines consist of cell populations still capable of differentiating In two cell lines (PCI and PCI 52), only markers for undifferentiated or proliferating cells could be detected; these cell...
... from the cell membrane and thus can mediate antibody-dependent cell- mediated cytotoxicity (ADCC) In addition, 5T4-transduced renal carcinomacell lines can be recognized by human T cells in vitro, ... http://www.translational-medicine.com/content/7/1/2 Figure Characterization of T cell responses Characterization of T cell responses (A) CD8+CD107a+ effector cells, (B) CD8+perforin+ effector cells, (C) PD-1+ T cells, (D) CD4+CD25+FoxP3+ Tregs ... and interleukin-2 for metastatic renal -cell carcinoma N Engl J Med 2001, 345:1711-1712 Diner EK, Linehan M, Walther M: Response of papillary renal cellcarcinoma in a solitary kidney to high...
... of renal tubules representing the origin of clear cell renal cellcarcinoma (RCC) and in the regulation of the cell cycle of parietal epithelial cells of the Bowman's capsule [10,11] Since UCHL1 ... chemical genomic screening of head and neck squamous cellcarcinoma [49] as well as pancreatic carcinoma lesions and pancreatic carcinoma cells either left untreated or treated with demethylating ... degradation pathway plays an important role in distinct cellular processes such as cell proliferation, cell cycle, apoptosis and intracellular signalling [8], which are often disturbed in cancers...
... Although cells other than T cells, such as NK cells and monocytes, present in PBMC utilized in the ELISPOT assays can secrete IFN-g, the majority of IFN-g secreting cells in the assays are T cells ... M: Cellular and humoral immune responses in patients with metastatic renal cellcarcinoma after vaccination with antigen pulsed dendritic cells J Urol 1999, 161:777-782 Melief CJ, Kast WM: T -cell ... alfa in metastatic renal -cell carcinoma N Engl J Med 2007, 356:115-124 Hiles JJ, Kolesar JM: Role of sunitinib and sorafenib in the treatment of metastatic renal cellcarcinoma Am J Health Syst...
... esophageal squamous cellcarcinoma Cancer 2004, 101:1994-2000 11 Samantaray S, Sharma S, Chattopadhyaya TK: Increased expression of MMP-2 and MMP-9 in esophageal squamous cellcarcinoma J Cancer ... collected from locations proximate to epithelial tumor cells, being within mm of an epithelial tumor nodule Normal epithelial and stromal cells were similarly collected from histologically normal ... N, Abnet CC, Hao CQ, Taylor PR, Qiao YL, Dawsey SM: Cytologic detection of esophageal squamous cellcarcinoma and its precursor lesions using balloon samplers and liquid based cytology in asymptomatic...
... pluripotent embryonic stem and germ cells [11,12] Recent data show that cells expressing high levels of Oct4 are present in breast cancer, bladder cancer and oral squamous cellcarcinoma and are associated ... hypopharyngeal squamous cellcarcinoma and analyzed the association between expression of Oct4/ Sox2, clinicopathological characteristics and prognosis of hypopharyngeal squamous cellcarcinoma Page of ... (A) High Oct4 expression in tumor cells, (B) low Oct4 expression in tumor cells, (C) high Sox2 expression in tumor cells, and (D) low Sox2 expression in tumor cells Ge et al Journal of Translational...
... adenocarcinoma cell lines (Bic-1 and Seg-1), human gastric adenocarcinoma cell lines (AGS, AZ521 and KATOIII), colorectal adenocarcinoma cell lines (Caco-2 and DLD1), a human cervix epithelioid carcinoma ... carcinomacell line (HeLa), a human lung adenocarcinoma cell line (A549), and human hematological malignant cell lines (acute promyelotic leukemia, HL60; human T cell lymphoblast-like cell line, ... biological actions in ESCC cells Methods Cell lines and cultures I) Five cell lines of human ESCC cells (OE21, TE5, TE8, TE10, and TE11), a non-malignant human esophageal squamous cell line immortalized...
... squamous cell carcinomas of the head and neck Cancer Res 1999, 59:1935-1940 35 Huang SM, Harari PM: Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: ... pathologists recorded whether tumor or stromal cells expressed ERCC1 The staining intensity was graded on a scale of 0-3, using adjacent nonmalignant cells as a reference (intensity 2) Five images ... 1) The high ERCC1 expression group had a higher T stage (T3-4) (p = 0.027) Those with squamous cellcarcinoma of the hypopharynx/larynx were found to have marginal lower expression of ERCC1 Interestingly,...
... a bright prospect in future Methods Cell Lines The human CCRCC cell line OS-RC-2 and mouse macrophage cell line Ana-1 were purchased from the Institute of Cell Biology, Chinese Academy of Sciences ... [20], the renal cancer cell line, phagocytic cells and endothelial cells were used to detect the toxicity of three modified PEI-derived materials in vitro The OS-RC-2 cells were seeded in 96-well ... determined based on cell percent with GFP expressing The number of GFP-expressing cells versus the total cell quantity in the microscope was defined as the transfection efficiency Cell counting was...