bacterial endotoxins and signaling events in the brain
Báo cáo y học: "Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenic/neurotrophic factors and neuroplasticity systems in the brain" pptx
... angiogenesis and neuronal signaling in the brain and are implicated in aging-induced cognitive deficits in SAMP8 Considering a role of the VEGFVEGFR2 signaling systems in cognitive function, we, in this ... decreased in the brains of older SAMP8, indicating aging-induced dysfunction of the VEGF-VEGFR2 signaling system Therefore, the impaired VEGF-VEGFR2 signaling systems likely induce a decrease in angiogenesis ... [2,3,31] Together, the present findings raise the possibility that CTSinduced reversal of impaired neurosignaling system in the brain of the SAMP8 groups is one of the outcomes resulting from enhancement...
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Báo cáo khoa học: Effect of 5-lipoxygenase inhibitor MK591 on early molecular and signaling events induced by staphylococcal enterotoxin B in human peripheral blood mononuclear cells doc
... of the Vb chain of the T cell receptor, which in turn increases cell proliferation and pro -in ammatory cytokine secretion [1] The present study aimed to investige the early signaling events induced ... the signaling cascades due to the leaking effect or the ability of the signal to use alternative signaling cascades upon the inhibition of the primary signaling pathway We are confident that the ... of inhibitors on SEB-induced TNF-a induction 14 000 H labeled thymidine incorporation (in cpm) The investigation then focused on analyzing the effect of the same set of inhibitors on TNF-a induction...
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Báo cáo khoa học: acids in the brain: D-serine in neurotransmission and neurodegeneration ppt
... the retina [67] Fig D-Serine localizes to neurons and astrocytes in the brain Staining for D-serine was performed in pyramidal neurons of layer V of the cerebral cortex and in astrocytes in the ... in the caudal part of the brain, including the adult cerebellum and brainstem (Fig 1) This is because of the emergence of d-amino acid oxidase in adult animals, which degrades endogenous d-serine ... that of glycine in the striatum and compara- in neurotransmission and neurodegeneration C H S T AON MOL OT D-Serine Fig Localization of D-serine in the rat brain The highest D-serine densities...
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báo cáo hóa học: " Tumor necrosis factor-mediated inhibition of interleukin-18 in the brain: a clinical and experimental study in head-injured patients and in a murine model of closed head injury." pot
... in the injured brain has not yet been investigated We sought to determine the interrelationship between intracranial TNF and IL-18 levels in a clinical study on patients with severe CHI and in ... concomitant beneficial and adverse effects of pro-inflammatory mediators, depending on the kinetic of their expression and posttraumatic regulation in the injured brain [3,12,13] However, the TNF-dependent ... alpha in brain injury Cytokine Growth Factor Rev 1999, 10:119-130 Lenzlinger PM, Morganti-Kossmann MC, Laurer HL, McIntosh TK: The duality of the inflammatory response to traumatic brain injury...
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Báo cáo lâm nghiệp: "Sexual reproduction in Populus I. Some physiological and biochemical events of the progamic phase" pdf
... concanavalin A-peroxidase reaction allowed the visualization of 15 stigmatic and pollinic glycoproteins according Differences to the glycoprotein type of increases were observed, distinct in the compat- ... to the presence of P nigra and P alba pollen tubes inside stigmatic tissues However, increasing protein bands were detectable, 0-20 h after pollination, only in compatible pollinated stigmas The ... studies focused on pollinic and stigmatic proteins, known to be involved in male-female interactions (Gaude and Dumas, 1987) After silver nitrate staining, qualitative and quantitative differences...
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Báo cáo y học: "Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport" doc
... PiT1-binding immunoadhesin generated by fusing the aminoterminal residues of the GALV (SEATO strain) Env, comprising the signal peptide, the RBD and the proline-rich region, to the rFc tag, herein, ... transporters in the brain In conclusion, our data suggest that these new metabolic markers can be used to improve our understanding of the metabolism in the brain, as well as in others organs such as the ... abundance in the striatum, the thalamus and the brainstem [24] In mice, only blood vessels were found to be immunostained using an antibody raised against the C-terminal part of the protein [25,26]...
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Báo cáo y học: " Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis" pdf
... prostaglandin D2 synthase, the transcription factor GATA-1, and the interleukin (IL)-13 inhibitory receptor IL13Rα2 [5, 8] In support of these in vitro data, the mature RasGRP4+ MCs that reside in the ... correspond to the C-terminal half of the CDC25-like catalytic domain in the signaling protein[1] The second most frequent isoform was variant which results in the loss of 69 of these same amino acids ... both at mRNA and protein levels This finding would open a new insight in the field of monocyte-lineage cell biology and of the diseases where this lineage cells play a prominent role In the latter...
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CHOLESTEROL INDUCED GENE EXPRESSION CHANGES IN THE BRAIN AND CEREBRAL VESSELS
... Abbreviations ICLAD Intracranial Large Artery Disease IDE Insulin-degrading enzyme IgG Immunoglobulin G IL12 Interleukin 12 IL-1β Interleukin-1β IL23 Interleukin 23 INSIG Insulin-induce gene IPA Ingenuity ... Cholesterol in the Brain The brain is the most cholesterol-rich organ in the body (Björkhem and Meaney, 2004) Although the human brain only accounts for 2% of the total body weight, it contains about ... Dietschy and Turley, 2004; Vaya and Schipper, 2007) In the brain, cholesterol is divided into two pools: major pool with 70% of the brain cholesterol residing in myelin sheaths, and minor pool with the...
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Gene expression changes in the brainstem and prefrontal cortex in a mouse model of orofacial pain
... different region of the brain i.e brainstem and PFC could play different roles in pain and contribute to different part of the pain system The use of KF38789 in inhibiting P-selectin and the use of mS100A9p ... inflammatory pain Inflammatory pain is due mainly to the action of prostaglandins and bradykinin, and substances released during the inflammatory process (Okeson and Bell, 2005) Together, they act to increase ... matter of the midbrain, the raphe nuclei, and other nuclei of the rostral ventral medulla Adapted from Purves and Williams, 2001 25 Chapter I Introduction Role of the brainstem in pain The brainstem...
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Distribution and role of calcium independent phospholipase a2 in the brain
... astrocytes and neurons (Luo et al 1998) In the rat, forebrain and midbrain are very lightly stained with cPLA2α antibody; the hindbrain in contrast, contains many densely labeled nuclei The dorsal and ... is the cessation of blood flow to the brain and disruption of metabolic demand During early stages of ischemia (within min), inositolcontaining glycerophospholipids are the main source of the increase ... Chapter I Introduction Arachidonic acid (AA) is distributed rather evenly in the gray and white matter and among the different cell types in the brain In resting cells, AA is stored within the cell...
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Distribution of betaine gaba transporter BGT 1 in excitotoxic brain injury and its role in osmoregulation in the brain
... function in the brain BGT-1 is capable of transporting both betaine and GABA, as examined in Xenopus oocytes and various cell lines But the physiological substrate of BGT-1 in the brain remains to ... betaine/GABA transporter BGT-1 in normal brain and in excitotoxic brain injury, as well as the expression and functional changes of BGT-1 in astrocytes in response to hyperosmolarity in vitro and ... hyponatremia causes brain edema as a consequence of influx of water into brain Due to increased intracranial pressure, brain edema leads to life-threatening cessation of the brain s blood supply and neuronal...
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2007 characterisation and mapping of bacterial wilt (ralstonia solanacearum) resistance in the tomato (so
... and advanced upto F3 using single seed descent (SSD) method (Tigchelaar and Casali, 1976) Seeds of F3 lines were then sent to the Institute of Plant Breeding of the University of the Philippines, ... 30 seconds, and 72oC for minute and soak at 10oC using a MJ PT-200 thermocycler (MJ Research, GMI, Inc., Minnesota, USA) Detection of amplified bands using silver staining Following amplification, ... “RIL-selfing” was used and the initial clustering of all markers into 37 linkage groups was based on a preset threshold recombination rate (RR) of 0.27 Initial linkage groups could be further merged into...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"
... bone graft in the damaged site and on the other hand, it creates an environment with a rich content of HA, with all the advantages deriving from the phenomenon The present study’s clinic and radiologic ... for the tools and facilitate the direct clinical view of the defect [fig 3-4] A full-thickness flap was elevated and the granulation tissue was removed showing the true extension and depth of the ... membrane in the treatment of infra bone defects, our clinical results are encouraging considering that in a similar study a mean value of the increase of the bone height of 0.5 mm was obtain with...
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TYPHOONS AND TECHNICAL SOLUTIONS RECOMMENDED FOR EXISTING AND NEW HOUSES IN THE CYCLONIC REGIONS IN VIETNAM
... of the coastline Winds acting on this sub-region are generated from strong typhoons directly approaching the coastline between Hai Phong and Ninh Binh, the coastline of Thanh Hoa and the southern ... typhoons and inundation are one of the many factors causing hunger and poverty hindering the socio-economic development of Vietnam Therefore, planning and construction of houses and buildings against ... level above the windows and door (to be replaced the lintel) in the brick wall and continuously run around the house The starting rebars should be arranged at the location where the roof-trusses...
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Food, Animal production and Human Comsumption in the Asian Region
... the world will sufficiently accommodate and feed its human population with out destroying the enviroment and depleting natural resources???” Land used by region and country group, 1961,1991 and ... wastes Weeds, marginal land Rice straw, corn stalk Other crop wastes trees, marginal land Poultry (Chicken, Duck & Turkey) Pig and small ruminant (Pigs, Goat & Sheep) Large ruminants ( Cattle, ... research and knowledge management Science based solutions to emerging issues 49 Livestock in a changing world Genetics and breeding Feed resources and Utilization Human resource International...
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Improvement of nutrient removal and phosphorus recovery in the anaerobic/oxic/anoxic process combined with sludge ozonation and phosphorus adsorption
... phosphorus was then accumulated in the sludge in the subsequent oxic tank by normal oxygen-utilizing PAOs The residual phosphorus was removed in the final anoxic tank without oxygen Especially in Phase ... ozonation) and effluent of the phosphorus adsorption column are shown in Fig During the operation, about 70% of the phosphorus in the sludge was solubilized by ozonation, and a large part of the solubilized ... 2008) The reactivated adsorbent was packed into the column again, and phosphorus was effectively adsorbed Figure Concentration of each type of phosphorus in the influent and effluent of the phosphorus...
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Characteristics of Leachate from Citrus Groves and their Changes in the Collecting Reservoirs in Matsuyama, Japan
... and periphery of the Seto Inland Sea The location of the research area and the distribution of the citrus groves in Matsuyama region are shown in Fig Matsuyama is situated in Shikoku Island in ... 66m, and 60m, respectively Stream water samples were collected at the middle parts of the grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the ... in the other stream The two streams flow together to be one stream and the sampling point St.4 is situated in the joined stream, which is the only stream that flows into the reservoir The reservoir...
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Cadmium Removal by the Hydroponic Culture of Giant Reed (Arundo donax) and Its Concentration in the Plant
... was removed within days in every run Assuming the zero-order kinetics, the average cadmium removal rates within the days calculated from the linear approximations of the plots in Fig were estimated ... concentration in giant reed as a result of Run 6, indicating that the cadmium was highly concentrated in the rhizome The transportation index, Ti, indicates the ability of the plant to translocate the ... cadmium, and is synthesized from glutathione (GSH) Inouhe et al (1994) reported that the cadmium binding complex containing PCs has an important role for the cadmium-tolerance of seedlings of...
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A STUDY OF THE RELATIONSHIP BETWEEN CEO COMPENSATION AND FIRM PERFORMANCE IN THE US AIRLINE INDUSTRY 2002 2006
... compensation and firm performance in the U.S airline industry may aid those seeking to invest in the industry as well as forward looking investment decisions by various groups interested in the U.S airline ... cyclical and the structure of the industry causes instability Hecker (2005) argues that the inherent instability of the airline industry can be traced to the structure of the industry and its ... … by diluting and distorting managers’ incentives and thereby hurting corporate performance” (p 72) The authors argue that the inability of the optimal contracting approach in explaining executive...
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