... 20 07, 38:1655- 171 1 Bravata DM: Intravenous thrombolysis in acute ischaemic stroke: optimising its use in routine clinical practice CNS Drugs 2005, 19:295-302 10 Sandercock P, Berge E, Dennis ... loaded Statistical Analysis Data were expressed as mean values (mean ± SD) Statistical analysis was adequately performed by analysis of variance, followed by Scheffe multiple-comparison post hoc ... after IS) (group 2, n = 10) , IS plus CsA (20.0 mg/kg at 0.5 and 24 hour, intra-peritoneal) (group 3, n = 10) , IS plus EPO (5,000 IU/kg at 0.5, 24, and 48 hour, subcutaneous) (group 4, n = 10) ,...
... × 106 ± 2.018 × 106 and 2.044 × 106 ± 1.462 × 106 , respectively, as a consequence of normal metabolism The addition of PM2.5 did not stimulate CL in NHV (3.425 × 106 ± 2.018 × 106 vs 2.889 × 106 ... Neutrophils (103 /mm3) 3.11 ± 0.55 3.84 ± 0 .74 0.0364 APO-A (mg/dL) 133.3 ± 19.93 165.0 ± 27. 59 0.0150 MPO (U/mg) 24. 17 ± 18.21 52.58 ± 25.44 0.0250 0. 07 ± 0.02 0.02 ± 0.02 0.0005 1 57. 6 ± 115.4 4 97. 6 ± ... 6) This response is reflected as higher susceptibility to lipoperoxidation in those patients (Figure 7) Discussion Oxidant generation is part of normal metabolism in many cell types and is critical...
... 67 68 69 70 71 72 73 74 75 76 77 78 79 nism of Ca2+ activation of the NADPH oxidase (NOX5) J Biol Chem 279 , 18583–18591 Grasberger H, De Deken X, Miot F, Pohlenz J & Refetoff S (20 07) Missense ... FEBS 3 275 Structure, regulation and evolution of Nox 176 177 178 179 180 181 182 183 184 185 3 276 H Sumimoto and of p47phox: conversion of a pagan NADPH oxidase to monotheism J Biol Chem 277 , 18605–18 610 ... p47phox, p67phox and Rac as cytosolic regulators, p47phox is dispensable for cell-free activation in the presence of excess amounts of p67phox and Rac [99 ,100 ] It is thus considered that p47phox...
... arthritis [26] It is obvious that tissues other than cartilage are participating in these processes, especially the surrounding synovial tissue This reflects the findings of Felson and coworkers [ 27] , ... knee joints Ann Rheum Dis 2001, 60 :1 07 0 -1 07 3 Enomoto H, Inoki I, Komiya K, Shiomi T, Ikeda E, Obata K, Matsumoto H, Toyama Y, Okada Y: Vascular endothelial growth factor isoforms and their receptors ... articular chondrocytes Ann Rheum Dis 2003, 62 :105 4 -106 0 Cerimele F, Brown LF, Bravo F, Ihler GM, Kouadio P, Arbiser JL: Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial...
... plagiarism and all materials appearing in this thesis/dissertation have been properly quoted and attributed I certify that all copyrighted material incorporated into this thesis/dissertation is in ... Measurement 17 2.6 Biomechanical Testing 17 2 .7 Histomorphometry 17 2.8 Cell Culture 19 2.9 FSS Studies 19 2 .10 Western Blot Analysis ... exercise in mice; this stimulates bone remodeling and osteoblasts to form new bone (11) 1.5 Disruptions in Bone Homeostasis When one type of cell becomes more active than the other, the homeostasis...
... morphologically distinct: further evidence for an apoptosis–necrosis continuum J Comp Neurol 378 , 88 104 FEBS Journal 274 (20 07) 1312–13 17 ª 20 07 The Authors Journal compilation ª 20 07 FEBS 13 17 ... levels comparable with normoxia This finding was expected, as it is reoxygenation, FEBS Journal 274 (20 07) 1312–13 17 ª 20 07 The Authors Journal compilation ª 20 07 FEBS 1313 Neuroglobin as ROS scavenger? ... explanation for why the retina is capable of tolerating an almost 10 times longer period of ischemia than brain They described how the presence of hypoxia in the retina is consistent with the finding...
... cytometry analysis Early apoptosis is defined by Annexin V+/PIstaining (Q4) and late apoptosis is defined by Annexin V+/PI+ staining (Q2) (C) and (D) HeLa cells were treated with cisplatin (8 μM) ... 8( 17) : 277 9-88 15 Lopez G, Liu J, Ren W, et al: Combining PCI-2 478 1, a novel histone deacetylase inhibitor, with chemotherapy for the treatment of soft tissue sarcoma Clin Cancer Res 2009, 15 (10) :3 472 -83 ... thus is a potent inducer of cell cycle arrest and apoptosis in most cancer cell types [10] However, a major limitation of cisplatin chemotherapy is that many tumors either are inherently resistant...
... 2000, 97: 975 3- 975 8 Cowley HC, Bacon PJ, Goode HF, Webster NR, Jones JG, Menon DK: Plasma antioxidant potential in severe sepsis: a 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 ... 2004, 2 87: R1014-R1030 Geiszt M, Leto TL: The Nox family of NAD(P)H oxidases: host defense and beyond J Biol Chem 2004, 279 :5 171 5-5 171 8 Nisimoto Y, Motalebi S, Han CH, Lambeth JD: The p 67( phox) ... number not for citation purposes) Critical Care 74 75 76 77 78 Vol 10 No Magder edge: direct interaction of TLR4 with NAD(P)H oxidase isozyme is essential for lipopolysaccharide-induced producκ...
... activationinduced T cell apoptosis Immunity 1999, 10: 73 5 -74 4 Barcellos-Hoff MH, Dix TA: Redox-mediated activation of latent transforming growth factor-beta Mol Endocrinol 1996, 10: 1 077 -108 3 Chen W, Frank ... smaller (Fig 7A, R2 green) and stained positive for Annexin-V and 7- AAD (Fig 7C) They exhibited higher MFI of ROS (Fig 7B) than that of live (Annexin-V -7- AAD) or early apoptotic (Annexin +7- AAD-) cells ... vs 18%) (Fig 10A) Consistent with the data of uninfected CD25- T cells (Fig 5), neutralization of TGF-β Page 10 of 16 (page number not for citation purposes) Retrovirology 20 07, 4: 57 http://www.retrovirology.com/content/4/1/57...