... between 3 H3 and 2
H6 or H6¢ is assigned as well as the intramolecular NOE between
3 H3 and H1.
Table 2. Intermolecular NOEs between West Nile virus (WNV)
NS2B–NS3pro(K96A) and inhibitors 2 and 3.
Protons ... half-filters
(mixing time 120 ms) were used to suppress intramolecular
NOEs of the protease and observe intermolecular NOEs.
For unambiguous identification of intraligand NOEs, the
experiment was also recorded ... intramolecular NOEs were
observed for a sample at 0.7 mm, indicating an effec-
tive molecularmass of > 500 Da. The possibility of
self-association made it harder to interpret the inter-
molecular...
... activated, and inhibited by G-protein bc subunits.
Types II (1088 amino acids) and IV (1064 amino acids) are calmod-
ulin insensitive and activated by bc subunits; type II is found in
brain and olfactory ... transcriptase
and HIV protease, and drugs to prevent microbial infections of
brain, respiratory and alimentary tracts and vagina. See
HIV.
acquired immunity or adaptive immunity immunity (active or pas-
sive, ... p and A are phosphoric and
adenosine residues, respectively, and a and n are small integers (a =
1, 2, or 3 and n commonly = 2, 3, or 4). Potent inhibitors of protein
biosynthesis in vivo and...
... James)
Chemical bonding andmolecular geometry from Lewis to electron densities / R.i.
Gillespie, P.L.A. Popelier.
p. cm
(Topics in inorganic chemistry)
Includes bibliographical references and index.
ISBN ... function
L = -
VZ
p for L = 0 au (blue) and L = 0.60 au (orange). The L = 0.60 surface shows the
charge concentations corresponding to the lone pairs on the sulfur atom and torodial charge
concentrations ... alt=""
... James)
Chemical bonding andmolecular geometry from Lewis to electron densities / R.i.
Gillespie, P.L.A. Popelier.
p. cm
(Topics in inorganic chemistry)
Includes bibliographical references and index.
ISBN ... function
L = -
VZ
p for L = 0 au (blue) and L = 0.60 au (orange). The L = 0.60 surface shows the
charge concentations corresponding to the lone pairs on the sulfur atom and torodial charge
concentrations ...
... standard molecularweight proteins. The flow
rate was set to 0.8 mL Æmin
)1
. The subunit molecular mass
was also estimated by SDS–PAGE.
Characterization and comparative analyses of
HYD
Js
and ... puri, purified proteins;
M, molecularweight standards. For the molecularweight stan-
dards, the bands from top to bottom correspond to 116.0, 66.2,
45.0, 35.0, 25.0 and 18.4 kDa, respectively.
Y. ... homotetramers [4]. Gel filtration analysis of native
HYD
Js
indicated a molecularmass of about 253 kDa,
and, as the subunit molecularmass of the His-tagged
recombinant HYD
Js
was estimated to be 56...
... Conformational studies on the selectin and natural
killer cell receptor ligands sulfo- and sialyl-lacto-N-fucopentaoses
(SuLNFPII and SLNFPII) using NMR spectroscopy and
molecular dynamics simulations. ... °Cat25°CÆmin
)1
,to220°Cat5°CÆmin
)1
and to
310 °Cat10°CÆmin
)1
.
ES-MS
Negative-ion ES-MS and CID MS/MS were carried out on
a Micromass (Manchester, UK) Q-Tof mass spectrometer.
Nitrogen was used as desolvation and nebuliser ... pattern
and sequence analysis of underivatized oligosaccharides by com-
bined MS/MS of singly and doubly charged molecular ions in
negative-ion electrospray mass spectrometry. J. Am. Soc. Mass
Spectrom....
... C
6
and C
9
aldehydes (and the
corresponding alcohol) were detected in all the samples and,
similarly to the pattern of LOX expression and activity,
their levels were higher in stage I seed and ... Hazelnut seeds contain reasonable levels of linoleic
and linolenic acid (about 10 and 0.2%, respectively, of the
total fatty acids) and hexanal and nonanal are among the
most abundant volatile compounds ... the shelf life and the organoleptic features of
hazelnut seeds, we carried out a study to characterize
hazelnut lipoxygenases at the biochemical and molecular
level.
Materials and methods
Plant...
... 5¢-GCCCACACC
AAT
ACCTATGCG-3¢) and the 3¢ complementary primer 5¢-AT
TAATGGCATGCTTTACCCGT-3¢.UsingthePCR
products of agmatinase with the GfiAandCfiT substi-
tutions in the coding and noncoding strands, respectively,
and ... of
B. caldovelox arginase (1cev), E. coli agma-
tinase (AUH) and rat liver arginase (1rla). H, S,
T and 3 stands for a-helix, strand, turn and
3
10
-helix. Conserved residues are marked by
an asterisk.
5524 ... aligned
with the sequences of 1CEV and 1RLA and pasted into the
structural alignment. The alignment was then corrected by
hand. Since the sequences of the two arginases and
agmatinase greately differ...
... the
caterpillar (was he so wrong?) and hence within the egg.
At this point, reasonable scientific study was abandoned by many
biologists and wish became the father of thought and the grandfather of
observation: ... organisation is laid down, we also
have to understand the interactions between the cells and the environment
in which they operate.
The range of cell andmolecular mechanisms underpinning morphogene-
sis ... autonomously reorganise themselves and
change their shape. The mechanism operates in a wide variety of vertebrate
and invertebrate tissues, but its mode of function andmolecular basis
remain unknown,...
... has effect on decreasing body
weight and blood lipid, FDA).
- Lot 1 and lot 6 did not treated with
mandarin peel extracts were expressed the
increase of body weight from 4% to 9.5%.
Fig. ... with standard
diet and drinking water ad libitum
+ Lot 2: Obese mice treated with ethanol
fraction and drinking water ad libitum
+ Lot 3: Obese mice treated with
chloroform fraction and drinking ... fraction and drinking water ad
libitum
+ Lot 5: Obese mice treated with
metformin (500mg/kg) and drinking water ad
libitum
+ Lot 6: Obese mice fed normal diet and
drink water (no treatment) and...
...
cholesterol (LDL-c) and glucose concentrations to be 67.3%, 46.2 %, 28.6 % and 18.3 %,
respectively as compared to ND mice. Our investigations show that anti-obesity and body weight
reducing effects ...
effect on decreasing body weightand blood
lipid, FDA).
Lot 1 did not treat with Docynia indica (W.)
Decne fruit extracts were expressed the increase
of body weight 11.9%.
N.T.T. Loan ... glucose concentration.
VNU Journal of Science, Natural Sciences and Technology 27 (2011) 125-133
125
Anti-obesity and body weight reducing effect of Docynia
indica (Wall.) Decne fruit extract...
... composition of its secre-
tion apparatus and the molecular details of its secretion mechanisms. This
review describes the molecular properties of the Cag-T4SS and compares
these with prototypical ... lack the cagPAI and
are less virulent.
The Cag secretion system is responsible for the
induction of a pronounced pro-inflammatory response
in vitro and in vivo, and the translocation and subse-
quent ... cagPAI and the properties of both conserved and
unique components of the Cag-T4SS, together with
potential implications for the current understanding of
its mode of action.
The cagPAI and the...
... Corresponding pH optima and specific activities
for syringaldazine and 2,6-DMP were pH 5.6 and 3.4 UÆmg
protein
)1
and pH 4.6 and 2.8 UÆmg protein
)1
, respectively.
In standard assay mixtures, ... growth. In order to better under-
stand these effects at the molecular level, we have now
purified and characterized one of these laccases, lac1, and
cloned and sequenced the cDNA encoding the ... sequences of lac1 and other fungal laccases. *, Amino acid conserved among all of the sequences. Ten His
residues and one Cys residue represent the amino acids that serve as Cu
2+
ligands and are shown...