... Lesions are always symmetric and bilateral, which is a typical pattern of metabolic encephalopathy In each of the cases we reviewed, including ours, there was symmetrical increase of T2 signal intensity ... reversible changes associated with the acute toxic effects of metronidazole are most likely due to axonal swelling with increased water content rather than a demyelinating process A further suggested ... the adverse effects of metronidazole and a need for early diagnosis of MIE Conclusions Our case illustrates that metronidazole can cause reversible neurotoxicity Appropriate neurological examinations,...
... Ontario (NA 6018), the Canadian Institutes for Health Research (MOP 13430 and 79533), by the Jean Davignon Distinguished Cardiovascular-Metabolic Research Award (Pfizer, Canada) and Genome Canada ... muscle pains consistent witha chronic pain syndrome, and bilateral frozen shoulders The patient has a strong family history for early coronary heart disease: her father had a myocardial infarction ... perfusion study, cardiac catheterization and coronary angiography, were all negative specifically showing no significant ischemia or coronary artery disease A 53-year-old woman from Ghana was referred...
... M, Hirai M, Tominaga N, Nakajima H, Elisseeva OA, Masuda T, Nakano A, Kawakami M, Oji Y, Ikegame K, Hosen N, Udaka K, Yasukawa M, Ogawa H, Kawase I, Sugiyama H: Wilms tumor gene peptide-based ... Ikegame K, Hosen N, Yoshihara S, Wu F, Fujiki F, Murakami M, Masuda T, Nishida S, Shirakata T, Nakatsuka S, Sasaki A, Udaka K, Dohy H, Aozasa K, Noguchi S, Kawase I, Sugiyama H: Induction of WT1 ... peptide vaccine and the resultant cancer regression Proc Natl Acad Sci U S A 2004;101:13885-13890 Kawakami M, Oka Y, Tsuboi A, Harada Y, Elisseeva OA, Furukawa Y, Tsukaguchi M, Shirakata T, Nishida...
... Alditol acetate, partially methylated alditol acetate, acetylated butyl glycoside and fatty acid methyl ester were analyzed by GC or GC-MS as described previously [7] SDS/PAGE was performed using ... spectra were estimated using DQFCOSY spectra; 9–10 Hz for 3J3,4 of residue a and 1–2 Hz for J1,2 of residue b The data are summarized in Table Residue a was assigned as a- L-rhamnopyranose (a- L-Rhap) ... Louis, MO, USA) Chemical degradation and separation LPS was hydrolyzed with 0.6% acetic acid at 105 °C for 2.5 h, and the reaction mixture was partitioned with chloroform/methanol/water (2 : :...
... 1994, a trial of interferon β-1b was discontinued because of increased spasticity, and she was not a candidate for glatiramer She had no history of diabetes, cardiovascular, liver or kidney disease ... (Table 1) and an EDSS score of 8.0 Neurological presentation included paraplegia, bilateral central scotomata with visual-field loss, dysphagia, chronic fatigue, cognitive impairment similar to mild ... throughout an additional 18 months Weight gain was evident as increased muscle mass and peripheral fat, mainly in the hips, gluteal area, and limbs Upper extremity strength and coordination progressively...
... δ-aminolevulinic acid (ALA), which is a weak gamma-aminobutyric acid (GABA) agonist that decreases GABA release by presynaptic inhibition [6,7] Lead is known to compete with metals like calcium, zinc, iron and ... separate areas were provided for the removal and storage of the lead-contaminated protective work clothing and equipment The regulatory body should make it mandatory to evaluate and create awareness ... lacking local and general exhaust ventilation and washing facilities culminating into alarmingly high blood lead levels of 128.3 µg/dl According to United States Occupational safety and Health Administration...
... prosthesis With these results, we conclude that an ambulating patientwith an above knee amputation and a subcapital fracture should be operated on after appropriate planning and preparation with satisfactory ... lever arm, and the patient was treated nonoperatively Two studies[4,6] have shown that this an appropriate strategy for most fractures after an amputation, except displaced intertrochanteric and ... plasty Postoperative xray with an uncemented bipolar hemiarthroPostoperative xray with an uncemented bipolar hemiarthroplasty We presented an ambulating above knee amputee, who had suffered a...
... >0.5 cm in diameter Wheal: A raised, erythematous, edematous papule or plaque, usually representing short-lived vasodilatation and vasopermeability Telangiectasia: A dilated, superficial blood vessel ... differential diagnosis (Table 52-4) For instance, the finding of scaling papules (present in patients with psoriasis or atopic dermatitis) places the patient in a different diagnostic category than would ... interpretation would be that the patient has a pruritic eczematous dermatitis with erosions caused by scratching Figure 52-1 Superficial spreading melanoma This is the most common type of melanoma Such...
... hair-bearing areas may be characterized by destruction of hair follicles Table 52-3 Common Dermatologic Terms Alopecia: Hair loss; it may be partial or complete Annular: Ring-shaped lesions Cyst: A soft, ... associated with xerosis and aged skin Systemic conditions that can be associated with pruritus include chronic renal disease, cholestasis, pregnancy, malignancy, thyroid disease, polycythemia vera, and ... epidermis without an associated loss of dermis Ulcer: Loss of epidermis and at least a portion of the underlying dermis Excoriation: Linear, angular erosions that may be covered by crust and are caused...
... usually advisable to assess the patient before taking an extensive history This way, the entire cutaneous surface is sure to be evaluated, and objective findings can be integrated with relevant ... individual lesions, and the arrangement of the lesions An ideal skin examination includes evaluation of the skin, hair, and nails as well as the mucous membranes of the mouth, eyes, nose, nasopharynx, ... red papules on the lower extremities that blanch with pressure can be a manifestation of many different diseases, but hemorrhagic red papules that not blanch with pressure indicate palpable purpura...
... A D The distribution of some common dermatologic diseases and lesions Figure 52-7 Psoriasis This papulosquamous skin disease is characterized by small and large erythematous papules and plaques ... skin disease is characterized by small and large erythematous papules and plaques with overlying adherent silvery scale Figure 52-8 ...
... contact (Fig 52-10) or primary irritant dermatitis In contrast, lesions witha generalized arrangement are common and suggest a systemic etiology Figure 52-9 Erythema multiforme This ... This eruption is characterized by multiple erythematous plaques witha target or iris morphology It usually represents a hypersensitivity reaction to drugs (e.g., sulfonylamides) or infections ... reaction to drugs (e.g., sulfonylamides) or infections (e.g., HSV) (Courtesy of the Yale Resident's Slide Collection; with permission.) Figure 52-10 ...
... psoriasis, or acne) 10 Social, sexual, or travel history as relevant to the patient DIAGNOSTIC TECHNIQUES Many skin diseases can be diagnosed on gross clinical appearance, but sometimes relatively ... malaise, fever, arthralgias) Ongoing or previous illnesses History of allergies Presence of photosensitivity Review of systems Family history (particularly relevant for patients with melanoma, atopy, ... Preparation A potassium hydroxide (KOH) preparation is performed on scaling skin lesions where a fungal infection is suspected The edge of such a lesion is scraped gently witha no 15 scalpel blade,...
... noting the amount of blanching that occurs Granulomas often have an opaque to transparent, brown-pink "apple jelly" appearance on diascopy Figure 52-11 Urticaria Discrete and confluent, edematous, ... erythematous papules and plaques are characteristic of this whealing eruption Wood's Light A Wood's lamp generates 360-nm ultraviolet (or "black") light that can be used to aid the evaluation ... such as freckles are accentuated, while dermal pigment such as postinflammatory hyperpigmentation fades under a Wood's light Vitiligo (Fig 52-12) appears totally white under a Wood's lamp, and...
... immunocompromised patients The gastrointestinal tract has been suggested as a source for A. xylosoxidans bacteremia in patients with cancer [12] Our case report is the first one associated with A. xylosoxidans ... that causes post-ERCP bacteremia Table 1: Key characteristics of A. xylosoxidans Tests Oxidase Catalase OF xylose OF glucose Arginine Citrate Ketoglutaric acid Gamma glutamil NO3 to NO2 Acetamide ... 23:569-576 Aisenberg G, Rolston KV, Safdar A: Bacteremia caused by Achromobacter and Alcaligenes species in 46 patients with cancer (1989–2003) Cancer 2004, 101:2134-2140 Gradon JD, Mayrer AR, Hayes...
... Holgate ST, Djukanovic R, Casale T, Bousquet J: Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on antiinflammatory activity and clinical efficacy Clin Exp Allergy ... lactose intolerance He was hospitalized in the Respiratory Department because of asthma exacerbation in 2004 and 2005 The patient was not sensitized to aero- and food allergens and his respiratory ... identified, as the range of potential allergenic agents is considerably larger than current Page of diagnostic reagents can address, so false-negative allergen-skin-test results are likely to happen Also,...
... and what started as an 'innocent bystander' may not be so innocent after all Figure Cranial MNR image in a coronal plane Cranial MNR image in a coronal plane The mass effect on the left lateral ... inpatient stay and received follow-up outpatient care with psychiatric and neurosurgical appointments Three months after discharge, the patient was working part-time and attending a technical ... cysts (of a congenital nature) and false ones, which are secondary to the post-inflammatory accumulation of CSF during cranial traumatisms, infections or intracranial haemorrhages [7,8] Arachnoid...
... of adenylate cyclase stimulated by TSH in normal patients; decreased thyroid iodine uptake; decreased release of T4 and T3; decreased hepatic metabolism of T4 to T3; and increased intrathyroidal ... illness Am J Med 1995, 99:575 Carmaciu CD, Anderson CS, Lawton CA: Case report: thyrotoxicosis after complete or partial lithium withdrawal in two patients with bipolar affective disorder Bipolar ... was started, and the patient reported her first night of good sleep According to Ms F and available collateral information, her TSH level had been depressed for more than three years, with a...