... 63-68 Corthier, G Cellular and humoral immuneresponse in pigs given vaccine and chronic hog cholera viruses Am J Vet Res 1978, 39, 1841-1844 Davis, W C., M J Hamilton, and Y.H Park Ruminant leukocyte ... Jeong, and B K Park Enhancement of host immune responses of sows using a non-specific immunomodulator p.22 Proceed 15th International Pig Veterinary Society Congress, Birmingham, England, 5-9 ... J H Gillespie, F W Scott, and J E Barlough Hagan and Brunners microbiology and infectious diseases of domestic animals pp.729-740 8th ed Comstock Pub Assoc., Ithaca and London, 1988 Yoon, I J.,...
... impaired mammary gland development and reduced numbers of natural killer (NK) and NK T cells These phenotypes in CIStransgenic mice are remarkably similar to those observed in STAT5a KO and/ or STAT5b ... including macrophages and Bacterial lipopolysaccharide (LPS) triggers innate immune responses through Toll-like receptor (TLR4) Other bacterial pathogens including proteoglycans and CpG-DNA also activate ... were abnormally accumulated in the thymus and spleen and produced high levels of BAFF/BLyS and APRIL, resulting in the aberrant expansion of B cells and autoreactive antibody production SOCS1-deficient...
... difference in the occurrence and evolution of acute and particularly late GU and GI toxicity between the two observed 3DCRT techniques To evaluate the association of immuneresponseand toxicity level, ... of resting and terminally differentiated NK cells correlated with several dosimetric parameters, and GI and GU toxicity Table summarizes the Pearson’s correlations between the immuneand dosimetric ... patient characteristics and main disorders are summarized in Table Acute and late GI and GU toxicities were studied in order to identify the treatment-related, clinical and patient characteristics...
... Recognition and IL-12 Induction A balanced interrelationship between host and parasite is highly dependent on the early induction of immuneresponse after infection Too much immuneresponseand pathogen ... Host Protection and Pathogen Evasion of ImmuneResponse During Tuberculosis Andre Bafica and Julio Aliberti Abstract An integrated response of the host is essential in health and disease Upon ... Protection and Pathogen Evasion of ImmuneResponse 2.4 2.4.1 31 Evasion of ImmuneResponse Cell Wall Components Mycobacteria are Gram positive and cannot be decolorized by acid alcohol and are...
... solution Med Chem Res 10, 493–501 Ferrandon D, Imler JL, Hetru C & Hoffmann JA (2007) The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections Nat Rev Immunol ... synthesis in larvae of Manduca sexta Arch Insect Biochem Physiol 8, 147–164 Kanost MR & Nardi JB (2009) Innate immune responses of Manduca sexta In Molecular Biology and Genetics of Lepidoptera ... mixtures were subjected to SDS-PAGE and immunoblotting using Spatzle antibodies The ¨ ¨ sizes and positions of molecular weight standards are indicated on the left Bands representing proSpatzle precursors,...
... Routine monitoring of immune responses is usually limited to the detection of humoral responsiveness and the capability of inducing adequate antibody titers represents the gold standard for virtually ... Smith Kline, Münchenbuchsee, Switzerland) and influenza (Inflexal, Berna Biotech, Bern, Switzerland) commercial vaccine preparations were used to monitor T-cell responses to vaccination Cell cultures ... Glutamax and non-essential amino acids (all from GIBCO Paisley, Scotland), thereafter referred to as complete medium, and 5% (v/v) human serum (Blutspendezentrum, University Hospital Basel, Switzerland)...
... and FT conceived the study, and participated in its design and coordination and helped draft the manuscript All authors read and approved the final manuscript Competing interests CB, CG, MM and ... concomitant medications, and laboratory tests Patients were monitored every weeks and as needed for adverse events Tumor responseand progression were assessed using Response Evaluation Criteria ... of IMP321, and experiencing an objective response after months of treatment, had an objective tumor regression between D85 and D170 In contrast, 50% and 71% of patients in the 1.25 mg and the 6.25...
... innate and adaptive immune responses] and they also remain high over time; VLPs generate a heterogeneous or polyclonal immune response: immunodominant and nonimmunodominat; neutralizing and non-neutralizing; ... natural HPV infection the immuneresponse is weak and typespecific Conversely, after administrating the HPV vaccine a strong and, although partially, cross-reactive immune- response was detected The ... vascular and lymphatic channels and to lymph nodes where immune responses are initiated; most DNA viruses have mechanisms for inhibiting interferon synthesis and receptor signaling, and papillomaviruses...
... and cell mediated immuneresponse Methods Protein expression and purification Freshly streaked bacterial colonies, containing the E7 plasmid [30], were inoculated in 25 ml LB medium (DIFCO) and ... immunization and progressively increased in mice immunized and times, reaching 1:8000 and 1:16000 respectively The presence of IgM and IgA was analysed in comparison with the IgG and the results ... analysis and interpretation of the data, in critical revision of the manuscript and in acquisition of funding PDB conceived and designed the study, analysed and interpreted the data and drafted...
... robust innate immuneresponse This same response can occur in response to endogenous ligands that also activate the CD14/TLR-4 pathway [2,3] Indeed, several endogenous CD14/TLR ligands have received ... generated by NADPH oxidase and myeloperoxidase (MPO), as well as cytokines and chemokines that can attract an adaptive immuneresponse Although originally identified as part of the response to exogenous ... CD14-dependent innate immuneresponse in macrophages While none of these data point to CD14 or innate immuneresponse as etiological in neurodegenerative disorders, these findings from in vitro and cell culture...
... evenly into groups of 5-7 animals for sampling time (0, 1, and days post-injury, DPI) and animals within these groups were randomised and placed in numbered cages to blind the strain of the mouse ... chemokine and cytokine expression in wild type and MT-I/II mice Plasma concentrations of Th1 and Th2 cytokines were assayed to determine if there were systemic differences in the inflammatory response ... was not observed after brain injury and local T cell specific cytokines were undetectable so Th1 and Th2 responses could not be compared directly in wild type and MT-I/ II-/- mouse injury sites...
... proinflammatory immune responses As possible markers of these changes in the immune system we investigated the proinflammatory cytokines IL-6 and TNF-a and measured the lymphocyte cell count Materials and ... Medicine and Toxicology 2010, 5:18 http://www.occup-med.com/content/5/1/18 deprivation and thereby an induction of proinflammatory immune responses [7-9] Cytokine levels correlate with fatique and ... disturbances and chronic sleep debt [1-6] To investigate the long-term influence of chronic sleep debt and circadian disruption on the immune system we compared cytokine production and lymphocytes...
... and cell mediated immuneresponse Methods Protein expression and purification Freshly streaked bacterial colonies, containing the E7 plasmid [30], were inoculated in 25 ml LB medium (DIFCO) and ... immunization and progressively increased in mice immunized and times, reaching 1:8000 and 1:16000 respectively The presence of IgM and IgA was analysed in comparison with the IgG and the results ... analysis and interpretation of the data, in critical revision of the manuscript and in acquisition of funding PDB conceived and designed the study, analysed and interpreted the data and drafted...
... mixed with the mineral salt and were vaccinated with one and two doses of rabies vaccine, respectively Cattle from groups V1 and V2 had only mineral salt and one and two doses of rabies vaccine, ... typically used to evaluate the humoral immuneresponse in cattle after rabies vaccination [1,8,11,12] Moreover, it is recommended by the Centers for Disease Control and Prevention (USA) The first serum ... Gharagozloo and Ghaderi [5] in humans, did not occur in cattle for rabies immunization Fig Mean rabies-neutralizing antibody titers from Nelore cattle on days 30 and 60 Cattle from groups FEV1 and FEV2...
... cells and were substantiated by a repeat experiment cells and either the same or slightly more Th1 cells than control mice (Figure 1A) Both CD4+ and CD8+ T lymphocytes are involved in the immuneresponse ... allergic immuneresponse by means of its effects on CD8+ T cells and dendritic cells in mice The results are consistent with a mechanism whereby CIN therapy decreases the innate immuneresponse ... prepared as above, and an amount containing 10 mg of pEGFP was administered intranasally to mice After 1, 3, and days, the mice were euthanized and the lungs were removed and fixed in buffered...
... with 20 ng/ ml TNF, 15 ng/ml IFN, ng/ml E2, and 500 U/ml IFN or null, and were co-stimulated with TNF and IFN, with IFN and IFN, or with E2 and IFN PBMCs were cultured at a final concentration ... downregulated genes in functional category of immuneresponse Network-based analysis of downregulated genes in the the functional category of immuneresponse (a) Network and (b) Network constructed by downregulated ... as IFIT1, IFIT3, OAS1, ISG15 and IRF7, and IL8RA were upregulated in vivo, but IFIT1, IFIT3, OAS1 and IL8RA were downregulated, while ISG15 and IRF7 showed almost no response to TNF in vitro These...
... cells might limit anti-tumour or microbial immune responses A strategic manipulation of TR cells might thus be used either to enhance or to dampen immune responses as required The identification ... S, Holland G, Thompson-Snipes L, Leach MW, Rennick D: Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4+ TH1-like responses ... control immune responses Most recently, several groups have demonstrated that glucocorticoid-induced tumour necrosis factor family related protein (GITR) is predominantly expressed at both the RNA and...
... in immuneresponseand inflammation in humans In particular, indirect effects of leptin or leptin deficiency are likely to considerably influence immune responses and inflammatory processes, and ... proliferation, and switched cytokine secretion toward a Th2 and T regulatory profile [76] Starvation and malnutrition are associated with reduced leptin levels and alterations of the immune response, ... protective effects in some models of innate immune response- mediated inflammation [81] Direct and indirect effects of leptin during immuneresponseand inflammation As mentioned above, leptin...
... changes in the immuneresponse to Bhsp65 Furthermore, both the cellmediated and the antibody responses to Bhsp65 were affected AA is driven by pro-inflammatory cytokines (IFN-γ and Page of 10 ... Nitric oxide and the immuneresponse Nat Immunol 2001, 2:907-916 31 Kim HR, Kim EY, Cerny J, Moudgil KD: Antibody responses to mycobacterial and self heat shock protein 65 in autoimmune arthritis: ... setting, and that this beneficial anti-arthritic effect of Celastrus is attributable in part to modulation both of the immuneresponse to the disease-related antigen Bhsp65 [22-25] and one of...