... onset of severe chest pain on mild exertion and at rest ECG at admission showed inverted T-waves in leads V2 to V5 and in lead aVL (Fig 3) During episodes of chest pain ECG revealed severe ST-segment ... months after valvereplacement with ECG at admission three months after valvereplacement with ST-T-abnormalities in the anterior leads Figure ST segment depressions during severe angina at rest ... apolipoprotein E genotype [6] Instrumentation with minimal trauma of the left main stem is most likely the cause of early postoperative stenosis after aorticvalvereplacement surgery [7,8,14] Avoiding...
... 91:1324-1329 Tarantini G, Buja P, Scognamiglio R, Razzolini R, Gerosa G, Isabella G: Aorticvalvereplacementinsevereaortic stenosis with left ventricular dysfunction: determinants of cardiac ... number of aorticvalve cusps, concomitant coronary artery bypass grafting, and magnitude of left ventricular systemic arterial peak systolic gradient in adults having aorticvalvereplacement ... heart diseases, in symptomatic patients with confirmed AS, surgical aorticvalvereplacement (AVR) is recommended, and the same approach is advised in the case of combined aorticvalve disease,...
... long-axis using the steady state free-precession (FIESTA) dynamic cine sequence at each time point Measurements of the mitral annulus, valve tenting angle and valve tenting area were meaured using standard ... pre-AVR, declined post-AVR (83 ± 30 to68 ± 11 ml/ m , p < 0.05) trending even lower by year but again remaining statistically insignificant (66 ± 10 ml/m2) LV stroke volume index increased rapidly ... defineable reduction in their MR grade (defined herein as through representing no (absent) through 2+ (moderate) MR In those patients the least amount of LV remodeling was present suggesting...
... after stented aorticvalve replacement, in a randomized cohort of 180 Page of patients [15] In group II (mechanical vs stentless) and in group III (stentless vs stented aorticvalve replacement) ... postoperatively the patient had a gastrointestinal bleeding and died before reaching the hospital Rethoracotomy for bleeding had to be performed in one patient in the stentless valve group, due to cardiac ... use of any tested valves in the respective age groups The personal preference and skill of the implanting surgeon will continue to play an important role in choosing a certain valve type Conclusion...
... B AAD was defined as nontraumatic dissection involving the descending aorta with initial intimal tear distal from the origin of the left subclavian artery Diagnosis was performed in all patients ... risk of death and to minimize the complications by excluding proximal intimal tear, removing associated aneurysmal disease and maintaining a complete distal perfusion The issuing advent of endovascular ... surgical repair but to define further knowledge on the role of endovascular stent-graft repairin the treatment of all descending aorta diseases including type B AAD We believe that our work contains...
... grafting (CABG) using saphenous vein grafts (SVGs) In one patient, the proximal end of the SVG was attached to the ascending aorta through an opening made in the Dacron graft The remaining patients ... after surgery Nine patients presented with aortic stenosis, while the remainder predominantly had aortic regurgitation At surgery, the aorticvalve was tricuspid in patients, bicuspid in patients ... performed without increasing the operative risk, [3,4,7,8] but the effect of such treatments on the remaining aorta remains unknown Here we are reporting the preliminary findings of the use of...
... replacement (AVR), or mitral and aorticvalve replacements (MAVR) using mechanical prostheses Page of The mitral valve was approached through the interatrial septum in most cases The aorticvalve ... year old There was (0.9%) major bleeding event in this series Severe upper gastrointestinal bleeding occurred in a 14 year-old boy nine days after MVR when the INR was 2.0 He required a laparotomy ... sickling crises has drastically reduced in both patients since undergoing mechanical valvereplacement with institution of anticoagulation Some workers have previously pointed out that warfarin...
... and TC analyzed and interpreted the patient data TB, HB and ST were involved in doing the literature review and manuscript preparation and MA was also instrumental in obtaining informed consent ... tremendously in the recent past more pertinently in the elderly population In the absence of large studies and longer follow up, clinical features and longterm behavior of this disorder is ambiguous Clinical ... echocardiographic parameters At one year of clinical and echocardiographic follow up after her mitral valve replacement, she showed a sustained and continuous improvement in her symptoms with no more hospitalizations...
... extending to the left ventricle Figure Schematic drawing of operative findings showing extensive calcification hindering the disc motion of the prosthetic valve Figure The explanted valve showing ... equine pericardial patch, could eliminate recurring paravalvular leak caused by severe mitral annular calcification extending to the left ventricle 8 Consent Written informed consent was obtained ... present a case of prosthetic valve disorder of the mitral valve with extended annular calcification which developed 27 years after the initial surgery, requiring redo valvereplacement three times...
... scarring Disadvantages include difficulty in exposing the atrium, ventricle and mitral valves, increased distance to mitral valve, and operation time [1,2] Sternal wound infection, either superficial ... mitral valve are satisfactory The advantages of these minimally invasive Figure Postoperative photograph of wound on day 10 after surgery (a) Signs of infection are not visible (b) Incision line ... dropped, ascending aorta was cross-clamped and the heart was arrested by retrograde perfusion of cold blood cardioplegia Mitral valvereplacement with a prosthetic valve (Mosaic Ultra Porcine Valve, ...
... breakthrough swelling including laryngeal edema Historically, his C1 INH levels were normal, but the C1 INH was dysfunctional, and he had a persistently low C4 level - typical findings in type HAE ... Edmunds LH Jr, Lambris JD: Inhibition of heparin/protamine complex-induced complement activation by Compstatin in baboons Clin Immunol 2000, 96(3):212-221 15 Weis M: Clinical review of hereditary ... INH due to plasma cascade activation allows bradykinin overproduction in patients with hereditary angioedema Bradykinin mediates acute swelling in these patients Reproduced with permission from...
... during rewarming phase, a source of bleeding was noticed from the posterior wall of the right inferior pulmonary vein Despite efforts to control the bleeding and repair the vein by adding interrupted ... on the pulmonary veins and thus increases the friability during suturing, c) the intrapericardial length of the vein is very short and in combination with the proximity of inferior vena cava's ... especially in patients with small left atrium, the integrity of the right pulmonary veins should be inspected just before completing the left atriotomy closure In the case of an injured vein, instead...
... performed in healthy controls (nine in the CEC and EMP study and five in the EPC study), taking no medication and carrying no cardiovascular risk Age at time point of investigation in the two ... vascular repair following endothelial injury in patients after CPR, circulating EPCs were measured in peripheral blood of resuscitated patients in a follow-up study Percentage of circulating EPCs in ... a significant rise in EMPs when comparing the two points in time after return to spontaneous circulation in the resuscitation group, reflecting an ongoing endothelial damage in the first 24 hours...
... group containing also individuals employed in full time jobs This paper examines the monetary incentives behind the tax benefit system for elderly workers in Ireland using an estimated replacement ... Gannon, 2009) By including working individuals, bias may be introduced with regard to the real incentives behind retirement behaviour, meaning that the potential behaviour change resulting from regulation ... point of retirement is mostly the result of an individual’s age and job sector, the second time point is more interesting from the policy point of view as it is an active individual choice instead...
... poly(ADP-ribosyl)ation during BER of a uracil-containing oligonucleotide Inhibition of PARP-1 poly(ADP-ribosyl)ation prevents BER in cell extracts To examine whether PARP-1 is involved in every single BER event ... for binding of XRCC1 and Polb to damaged DNA C Fig Involvement of PARP-1 in BER in human cell extracts (A) A uracil-containing (left panel), or the corresponding control (right panel) biotinylated ... of PARP-1 depletion on the cross-linking efficiency of BER proteins during repair of a uracil-containing substrate Instead, removal of PARP-1 accelerated the loading and subsequent dissociation...
... outside of demyelinated lesions Our finding of changes in cytokine expression following NG2 ablation may also be important in understanding changes in demyelination and remyelination in the NG2 null ... were obtained using eriochrome cyanin staining to quantify the extent of myelin damage (data not shown) Thus, despite the initially larger extent of inflammation and loss of myelin in wild type ... role of NG2 in multiple cell types during the processes of demyelination and remyelination Following microinjection of L-a-lysolecithin into the spinal cord white matter, we have investigated...
... halo itself included pin loosening, superficial, and deep pin tract infections Brain abscess has also been previously described with halo pins [24] Halo-femoral traction compiled certain neurological ... spinal release and halo-femoral traction in the management of severe spinal deformity in 2004 Twenty-four patients were treated with halo-femoral traction at the interval between anterior spinal ... method in the treatment of this formidable disease Combined with anterior spinal release and posterior fusion, it could notably reduce the incidence of severe complication such as spinal cord injury,...
... fracture healing in the group receiving an injection of 100 μg TP508 into the fracture gap This is in agreement with previous studies showing the benefit of TP508 in enhancing healing of various ... structural integrity of the fracture site The external fixators were removed by cutting through the pins using a diamond cutting disc and a haemostat to prevent pin spinning The pin remnants ... μg TP508 in 20 μl PBS into the fracture gap and Group IV as the control group received an injection of 20 μl PBS saline into the fracture gap Mechanical testing After termination, the skin over...
... the manuscript in its final form RT contributed to analyzing the data and interpreting the results, revising the manuscript, and approving the manuscript in its final form Competing interests The ... data, analyzing the data and interpreting the results, drafting and revising the manuscript, and approving the manuscript in its final form RA, KK, and JO contributed to acquiring and managing the ... despite the increase in THI in the full sample, there was an improvement in NIRVO2 in patients with altered baseline and deterioration in NIRVO2 in patients with preserved baseline in both the...