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antioxidation activity in vivo

Tài liệu Báo cáo khoa học: ATPase activity of magnesium chelatase subunit I is required to maintain subunit D in vivo ppt

Tài liệu Báo cáo khoa học: ATPase activity of magnesium chelatase subunit I is required to maintain subunit D in vivo ppt

Báo cáo khoa học

... double-ringed BchI-BchD structure the ATPase activity of BchI isblocked. A conformational transition upon binding toBchH may bring the integrin I domain of BchD into contactwith the integrin-binding ... ion coordination motifcharacteristic for integrin I domains [10]. Integrins areknown to participate in cell–matrix and cell–cell interactions[14,15]. They are involved in signalling to and ... catalyzing cobaltinsertion in hydrogenobyrinic acid a,c-diamide during coenzymeÓ FEBS 2004 ATPase activity is required to maintain subunit D (Eur. J. Biochem. 271) 2187cDNAwasthenusedinanordinaryPCRamplificationand...
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Báo cáo y học:

Báo cáo y học: "Expression of Human Globular Adiponectin-Glucagon-Like Peptide-1 Analog Fusion Protein and Its Assay of Glucose-Lowering Effect In Vivo"

Y học thưởng thức

... characterized by insulin re-sistance and insulin secretion deficiency. At present, there is no a single medication which treats type 2 diabetes by improving both insulin resistance and insulin secretion ... glycine-rich linker is flexible, which allows the specific engineering of hinge regions into proteins to achieve desired functional motions [17]. We used a glycine-rich short peptide including ... fusion protein in inclusion body was refolded in urea gradient refolding buffer. And then, the refolded protein was incubated with enterokinase to remove the His-tag. The fusion protein without...
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Báo cáo y học:

Báo cáo y học: "Relationship between Anti-CCP Antibodies and Oxidant and Anti-Oxidant Activity in Patients with Rheumatoid Arthrit"

Y học thưởng thức

... arthritis. Clin Rheumatol 2000;19:275-277. 29. Bandt MD, Grossin M, Driss F, Pincemail J, Babin-Chevaye C, Pasquier C. Vitamin E uncouples joint destruction and clinical inflammation in a transgenic ... acid citrulline, for example, citrullinated fibrin, which is found in the rheumatoid joint [21]. The citrulline moiety, which is the essential part of the antigenic determinant in these antigens, ... peptidyl arginine deiminases (PAD) [22]. Some reults in the literature also suggest that anti-CCP may be related increased oxidative activity in RA patients. For ex-ample, TNF-alpha inhibitors...
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Báo cáo y học:

Báo cáo y học: "Serum cholesterol concentration associated with aspirin esterase activity in older people: preliminary data"

Y học thưởng thức

... circulating aspirin esterase activities are mainly due to butyrylcholinesterase (BChE, pseudocholinesterase) and, in part, to albumin (6). Because of higher aspirin esterase activity lead-ing ... cholesterol and aspirin esterase activity were measured in the pre- and post-interventional phases of the study. RESULTS: During the interventional period, the changes in aspirin esterase activity cor-related ... aspirin in the population (2, 3). Increased hydrolysis of circulating aspirin, pharmacokinetically corresponding to faster Int. J. Med. Sci. 2010, 7 http://www.medsci.org 91elimination...
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Báo cáo y học:

Báo cáo y học: "Matrix Metalloproteinase Activity in Pediatric Acute Lung Injur"

Y khoa - Dược

... containing 1 mg/ml porcine skin gelatin in the presence of SDS under non-reducing conditions. Fol-lowing electrophoresis, gels were washed in 2.5% Triton X-100 for 1 hour at 4°C, then incubated ... demonstrated an increase in MMP-9 and NGAL levels (neutrophil gelatinase-B associated lipocalin complex) in lung fluid obtained on postnatal days 2 and 4 from premature infants recovering from RDS, ... MMP-9:TIMP-1 Activity in Pediat-ric ALI Since TIMP-1 normally provides negative regu-lation to MMP-9 in tissue compartments, we exam-ined TIMP-1 activity and MMP-9:TIMP-1 activity ra-tios in our...
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Tác dụng kháng viêm in vivo của dẫn chất polyoxychalcon

Tác dụng kháng viêm in vivo của dẫn chất polyoxychalcon

Y khoa - Dược

... 2’-hydroxy quan trọng đối với tác dụng kháng viêm in vivo của các chất thử nghiệm, kết quả kháng viêm in vivo phù hợp với kết quả kháng viêm in vitro đã công bố trước đây. [2] [6] Các dẫn ... có thể không ảnh hưởng đến hoạt tính kháng viêm in vivo, trong khi các nhóm methoxy trên vòng B làm tăng tác dụng kháng viêm in vitro và in vivo của chalcon. 3 4 5 6 7 8 9 10 G3 G4 ... tiến hành khảo sát tác động kháng viêm in vivo trên chuột nhắt trắng trên mô hình gây viêm với carrageenin 1%. Liên quan cấu trúc và tác dụng kháng viêm in vivo cũng được bàn luận để định hướng...
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Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier

Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier

Tài liệu khác

... xed in 10% phosphate buered formalin, embedded in paraf-n, sectioned, and stained with hematoxylin and eosin (H&E). In vivo pharmacokinetics and bioavailability In vivo pharmacokinetic ... Zhi-Min Zhou1, Hong-Li Chen1, Xue-Min Li1, Ling-Rong Liu1, Yin-Song Wang3, and Qi-Qing Zhang1,2 1Institute of Biomedical Engineering, Chinese Academy of Medical Sciences, Peking ... hydrophobized polysaccharide/oncoprotein complex vaccine induces in vitro and in vivo cellular and humoral immune responses against HER2-expressing murine sarcomas. Cancer Res. 58:3385–90.Gustafson,...
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Tài liệu Sport and Physical Activity in Children with Congenital Heart Disease ppt

Tài liệu Sport and Physical Activity in Children with Congenital Heart Disease ppt

Sức khỏe trẻ em

... surgery/interventions (including ablations)1.1 Without remaining findings (complete correction)1.2 With minimal findings1.3 With clinically significant findings1.4 After palliative interventions:1.4a ... UnlimitedB Mild (remaining) findings1.2; 2.1; 2.2; 2.3; 2.4; 4.2 UnlimitedC Clinically significant (remaining findings) 1.3; 5.1; 5.2; 5.3 No competitive sportsD Severe (remaining) findings 1.4a; 1.4b; ... exercise include interval training at moderateintensity, e.g., ball games and running games, or moderate stamina training. Their afterloadreducing effect should even result in a protective cardiac...
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Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx

Báo cáo khoa học

... triglyceride, glucose, leptin andinsulin, and insulin sensitivity, in TG miceAfter 6 weeks of normal or HF diet, serum levels oftriglyceride, glucose, leptin and insulin were deter-mined (Fig. 4A). ... improvement in peripheral insulin resis-tance through the activation of PPARc in WAT, it ispossible that PGD2stimulates pancreatic islets toincrease insulin secretion. Indeed, serum insulin levelswere ... levelswere increased after treatment with thiazolidinediones in diabetic mice through regulation of insulin produc-tion in pancreatic islet cells [39–41]. Thus, theincreased insulin level seen in H-PGDS...
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Tài liệu Báo cáo khoa học: Exposure of IgG to an acidic environment results in molecular modifications and in enhanced protective activity in sepsis doc

Tài liệu Báo cáo khoa học: Exposure of IgG to an acidic environment results in molecular modifications and in enhanced protective activity in sepsis doc

Báo cáo khoa học

... lgÆmL)1(lines 1–3) and 50 lgÆmL)1(lines 4–6). (C) Increased binding of pH 4 buffer-exposed IVIg to recombinant human IFN-c. (D) Increased binding of low-pH buffer-exposed IVIg to human factor H. In ... hyperreactivity of body defensemechanisms. In addition to sepsis, there is an increasing numberof emerging infectious diseases in which the severe gen-eralized in ammatory reaction of the infected ... to a pH 4 buffer resulted in an increase in its pre-existing binding to antigens present in anEscherichia coli lysate, and in the appearance of somenew bands showing the acquisition of new...
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Tài liệu Báo cáo khoa học: Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma pptx

Tài liệu Báo cáo khoa học: Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma pptx

Báo cáo khoa học

... randomized. No binding was detected in buffer lacking Ca2+for any of the proteins tested.Protein binding equilibrium data (Req) were fitted to a one-site binding hyperbola according to the relationship ... anticoag-ulant activity that is not dependent on membranebinding. In human proteins, protein S binds to theprotein C Gla domain. Although this interaction hasbeen mapped to Gla regions C-terminal to ... folded membrane-binding domain [9,10]. ThisCa2+binding requires the presence of Gla residues.The Gla domains within the protein C family comprise44 amino acids and contain between nine and 11...
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Tài liệu Báo cáo khoa học: The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo pdf

Tài liệu Báo cáo khoa học: The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo pdf

Báo cáo khoa học

... Relative luciferase induction /activity Relative luciferase induction /activity Relative luciferase induction /activity Relative luciferase induction /activity Relative luciferase induction /activity Relative ... The subsequentincubation with the indicated retinoids was then terminatedat the indicated time points by washing with NaCl ⁄ Piandlysis of the cells using 1 mL of Trizol (Invitrogen) per ... microcen-trifuge tubes containing beads were vigorously shaken in amicrotube shaker for 20 min at room temperature. Afterremoving the retinoid solution, the beads were washed twicefor 20 min in 200 lL of...
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Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

Báo cáo khoa học

... insulin signaling, and that it may repre-sent an interesting molecule with which to regulateliver insulin action.Experimental proceduresMaterialsPorcine insulin, recombinant human insulin, ... Removal of Grb14 from fractions of insulin-treated ratsby KCl treatment led to an increase of in vivo insulin-stimulated IR tyrosinekinase activity, indicating that endogenous Grb14 exerts a ... [15]. The binding of ZIP to Grb14, byrecruiting protein kinase Cf, enhances the serine phos-phorylation of Grb14 and its inhibitory effect on IRkinase and insulin signaling [10]. The interaction...
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Tài liệu An Empirical Analysis of Political Activity in Hollywood pptx

Tài liệu An Empirical Analysis of Political Activity in Hollywood pptx

Sân khấu điện ảnh

... mechanisms. 4 Next, each individual in the data was linked to personal demographic information. Since the individuals in the dataset are the objects of intense public interest, it was usually ... (jointly) significant in determining contributions, but has the opposite shape as it did for actors: contributions are decreasing in age for the relatively young, then begin to increase in ... film or entertainment-specific price index. Since the individuals in the sample are concentrated in certain areas of the country (southern California and New York, e.g.), and since their typical...
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Tài liệu Visual Activity in Hollywood Film: 1935 to 2005 and Beyond docx

Tài liệu Visual Activity in Hollywood Film: 1935 to 2005 and Beyond docx

Sân khấu điện ảnh

... this shift maintains itself throughout the larger inter-vals. The single bar at one hour represents the finding that in allpossible 1-hr intervals across the film, the VAI maintains itselfbetween ... considering the VAI fluctuations in a single, high intensity film. These are shown in Figure 8 for TheBourne Ultimatum. We first parsed this 105-min film into 632consecutive 10-s intervals (e.g., including ... absolutevalue of the difference in pixels for film image pair. Blackness indicates nochange in the pixels; increasing lightness indicates increasing differences in pixels across the pair. Images...
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