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... weaklyorinconsistentlyenforcedThisreportwillnotexploretheissuesofmonitoringandenforcement,althoughtheseareseriousconcernsthatneedtobeaddressedbypolicymakers.Atpresent,monitoringandcomplainthandlingbodiesdonotenforcecompanyledinitiatives.Alackofanindependentcomplaintmechanismcanleaveconsumersfrustrated,andalackofenforcementallowscompanyledinitiativestoberolledbackatanytime.Ifamonitoringandcomplainthandlingbodywereestablisheditwouldneedtogainconsumerconfidence,forwhichitwouldneed(a)tobetransparentinoperationwithroutineregularpublicationsoftheiractivities;(b)tobeindependentandfreefromindustryinfluence,andseentobeso;and(c)toensurethattheirservicesareeasilyandinexpensivelyaccessedbyconsumers.Penaltiesmustbecommensuratewiththesizeofthemarketingbudgetsinvolvedandwiththeestimatedexposureofchildrentotheoffendingcommercialmessages.Afurtherconcernistheneedtoensurethat,whateverthedifferencesindefinitionsorapproaches,allcompaniesshouldmakesomecommitmenttoofferselfrestraint.IntheEuropeanregiononly11companieshavejoinedthescheme,alongwiththeEuropeanSnacksAssociation.Severalmajorcompanies,includingMcDonalds,KFCandHaribo,andmanysmalleronesarenotincluded.ProblemsofdefinitionsCompanieschoosetherulestoimposeuponthemselves.Asaresulttherearelikelytobediscrepanciesandinconsistencies.HereweshalllookatsuchproblemsencounteredwithinthepledgesandpromisesandactivitiesundertakenbycompaniesintheEuropeanUnion.Whatageisachild?ThetablebelowprovidesexamplesofdefinitionsoftheagerangeforchildbycompaniesparticipatingintheEUpledgescheme.Pleasenotethattheinterpretationofacompanypolicycanbecomplex,andreadersareadvisedtocheckthecompanystatementsforthemselves(hyperlinksareprovided). ... 0‐12**≥50%ofaudiencemustbechildren;**≥35%ofaudiencemustbechildren;***≥30%ofaudiencemustbechildren.****≥25%ofaudiencemustbechildren.~unlessanadultispresent.~~unlessadultspredominate.+≥35% for someshowsand≥50% for others.++11 for printmedia,otherwise12.Whichproductscanbepromoted?IntheUSAalargenumberofcompany‐promotedmodelshavebeenproposed for definingthenutritionalcriteria for foodstobemarketedtochildren21andasimilarproblemhasariseninEurope.Thenexttablegivesexamplesofnutrientmethods for definingfoodsassuitable for marketingtochildren,asproposedbysomeofthecompaniesintheEUpledge:Table2Company‐setcriteria for foodstheycanmarkettochildrenCompany ... TheStanMarkprojectbringstogetherresearchersandpolicy‐makerstodevelopasetofstandards for marketingfoodsandbeveragesconsistentwiththeresolutionoftheWorldHealthAssembly.ObjectivesConveneaseriesofmeetingsinEuropeandtheUSAtobringtogetherkeymembersofthescientificresearchcommunityandpolicy‐makingcommunitytoconsiderhowmarketingfoodandbeveragesmayaffectchildren’shealth.Identifycurrent‘bestpractice’approachestothecontrolofmarketing,includingmeasuresnotspecificallyaddressingfoodandbeveragemarketing,ornotspecificallydirectedtotheprotectionofchildren.Exploretheuseofstandardsandmarketingcodestoinfluencecommercialactivity,includingstandardsfromotherindustrialsectors.Proposeasetofstandardstoformthebasis for across‐bordercodeofmarketingoffoodsandbeverages.Developweb‐basedresources for policydevelopmentconcerningfoodandbeveragemarketingtochildrenandrelatedmaterialstosupportpolicydevelopment.Projectpartners...

Báo cáo khoa học: 15 N-Labelled proteins by cell-free protein synthesis Strategies for high-throughput NMR studies of proteins and protein–ligand complexes doc

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... highyields in vivo are also suitable for efﬁcient productionby cell -free synthesis. In order to compensate for theincreased effort and expense required for the produc-tion and selective isotope ... [15N]-labelling achieved by cell -free pro-tein synthesis has been demonstrated for each of the19 nonproline residues [18]. Time and expense can bedrastically reduced by use of cell -free systems[11,18,21], ... [15N]-labelledproteins makes it an attractive tool for preliminarystudies prior to the production of uniformly [15N ⁄13C]-labelled samples for in-depth NMR analysis. Muchinformation can be gleaned already...

Báo cáo khoa học: Optimization of an Escherichia coli system for cell-free synthesis of selectively 15N-labelled proteins for rapid analysis by NMR spectroscopy pdf

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... for Saccharomyces carlsbergensis, no data available for E. coli;bvalue for Lupinus luteus and bovine, no data available for E. coli;cvalue for Paracoccus denitriﬁcans, no data available for ... acidschosen for hCypA labelling were 50 lM for [15N]Trp and[15N]Tyr, 150 lM for [15N]Ile, [15N]Thr and [15N]His,0.35 mM for remaining Group II [15N]amino acids, and1mM for those ... application for this method is in production ofselectively isotope-labelled samples, as in vitro expressionuses much smaller volumes and therefore requires corres-pondingly smaller quantities of expensive...

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... approach is to use a single hopto form each (physically) long-distance link, with the signalremaining in the optical domain throughout. Since a high-performance free- space optical system can carry ... signalcan go through in the network before becoming too weak.Therefore, it is important to establish the maximum numberof stages.In this paper, an experimental demonstrator has beenbuilt ... re<rcrosstalk), it is clear that thesystem BER perform ance is directly controlled by the OMA.Therefore, in order to optimize BER performance, the OMAshould be as large as possible.From...

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