and metastasis initiating cells associated with their resistance to current cancer treatments

Báo cáo y học: "High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis" potx

Ngày tải lên : 09/08/2014, 01:23

... RA and OA patients were histopathologically assessed to confirm the clinical diagnosis and to ensure typical pathologic characteristics of RA and OA Infiltration of T as well as B cells and their ... chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions J Clin Invest 1998, 101:746754 Murdoch C, Finn A: Chemokine receptors and their role in ... (IFN)-gamma together with IFN-gamma receptor in the rheumatoid synovial membrane compared with synovium of patients with osteoarthritis Br J Rheumatol 1996, 35:24-32 Stiehl P: Histologie der Rheumatoid-Arthritis...

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Tài liệu Báo cáo khóa học: Point mutations associated with insecticide resistance in the Drosophila cytochrome P450 Cyp6a2 enable DDT metabolism doc

Ngày tải lên : 19/02/2014, 12:20

... very grateful to Dr Waters and Dr Ganguly for providing us with the full-length CYP6A2 cDNA, to Dr T Friedberg for providing us with the pCW vector and to Dr Rahmani for the facilities to analyze ... binding spectra associated to DDT and to testosterone are type I spectra (data not shown) and Table Speciﬁc production of the DDT metabolites by each of the CYP6A2 variants The mean ± SD and the number ... apoenzymes instead First, we used testosterone to probe the activity of the CYP6A2 enzymes All the variants were able to hydroxylate testosterone to give a metabolite with no signiﬁcant differences...

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Visitor Profiles, Economic Impacts and Recreational Aesthetic Values Associated with Eight Priority Florida Springs Located in the St. Johns River Water Management District pot

Ngày tải lên : 08/03/2014, 08:20

... can also impair and harm economic activity connected with aquatic communities such as wetlands, streams and lakes, and springs for which Florida is famous with residents and visitors An important ... ingress and egress for visitors passing through the area on their way to popular Florida destinations In 2002, out of state domestic visitors (U.S.) to Marion County were 1.1% of all the visitors to ... visitors, 77% of the demand is concentrated in the 2nd and 3rd quarters of the year It is quite obvious that the factors governing seasonal demand for day visitors at Silver Glen and Alexander...

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SPECIAL REPORT: National Survey of Children’s Health Finds Intact Family and Religious Participation Are Associated with Fewer Developmental Problems in School-Age Children pdf

Ngày tải lên : 28/03/2014, 09:20

... explanatory factors And their associations with children’s developmental difficulties are comparable in magnitude to the associations with family income and poverty, low parent education, and minority-group ... structure and the quality of the relationship with their parents Children who live with both biological parents or two adoptive parents are most likely to have a high-quality relationship with their ... Representatives to design and produce three editions of the Committee's report, U.S children and their families: Current conditions and recent trends He was a member of the National Committee on Vital and...

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báo cáo hóa học:" Patient and surgery related factors associated with fatigue type polyethylene wear on 49 PCA and DURACON retrievals at autopsy and revision" pptx

Ngày tải lên : 20/06/2014, 01:20

... (1 to -12) 2.4 (5 to -2) 1.0 (5 to -9) -8.1 (-4 to -13) -4.9 (-5 to 2) 1.1 1.0 -3.2 (5 to -12) 2.3 (6 to -6) -1.9 (2 to -11) -5.8 (12 to -10) -2.5 (-9 to 7) 1.2 10 1.8 Prosthesis Related Factors ... (7.0 to 21.0) 10.5 (7.0 to 21.0) 73.6 (53.7 to 87.1) 7/4/6 (N = 17) 23.4 (16.3 to 29.4) 0.9 (18 to -28) 0.2 (N = 16) 2.6 (N = 16) 66.0(48.4 to 80.3) 3/8/11**(N = 22) 26.6 (16.7 to 39.2) 1.2 (28 to ... factors between autopsy and revision group Because in theory we expected autopsy retrievals to have lower mean wear score, we also expected patients that used their prosthesis till the end of their...

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Báo cáo hóa học: " Nucleotide mismatches between the VP7 gene and the primer are associated with genotyping failure of a specific lineage from G1 rotavirus strains" potx

Ngày tải lên : 20/06/2014, 01:20

... lineage III (blue) and lineage IV (red) lected to understand this complex epidemiology [15] However, in recent years it was reported that the accumulation of point mutations in VP4 and VP7 genes was ... and one for P-typing [25] In the one developed by Gouvea et al [24], it was reported failures in the correct genotyping of G2, G8, G9 and G10 rotavirus strains [7,12,17,20,21], and In order to ... grouped within one of the four lineages previously reported by Jin et al [5] (Fig 1) The typeable and untypeable G1 strains reported by Rahman et al [19], grouped within the lineage I with a high...

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báo cáo hóa học:" Women''''s quality of life is decreased by acute cystitis and antibiotic adverse effects associated with treatment" pptx

Ngày tải lên : 20/06/2014, 15:20

... isolated, resistance to TMP/SMZ, ciprofloxacin and nitrofurantoin were 7%, 1% and 8%, respectively For E coli the resistance rates were 7%, 0% and 4% for TMP/SMX, ciprofloxacin and nitrofurantoin, ... 54 randomized to Ciprofloxacin lost to follow-up 51 randomized to Nitrofurantoin lost to followup and scheduled for surgery ;surgeon request different treatment 146 analyzed for outcome and adverse ... that patients with culture negative cystitis are more sensitive to the impact of cystitis symptoms on their QOL compared to those with positive urine cultures That is to say that while their urine...

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Báo cáo sinh học: " Research Article A Contourlet-Based Image Watermarking Scheme with High Resistance to Removal and Geometrical Attacks" pptx

Ngày tải lên : 21/06/2014, 16:20

... watermark into the 1st and the 4th subband, and thus we could embed 34 KB of data into the host image without degrading its perceptual quality Embedding the watermark in other subbands with lower ... noise, and geometrical distortion On the other hand, the watermark at low-frequency subbands of an image is sensitive to other image processing algorithms such as histogram equalization and cropping ... scaling, and histogram equalization We compared the robustness of the proposed method with other contourlet methods under cropping, Gaussian noise, and rotation attacks Compared to the DWT-based and...

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Báo cáo toán học: "Positive cones and $L^p$-spaces associated with a von Neumann algebra " pptx

Ngày tải lên : 05/08/2014, 10:20

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Báo cáo lâm nghiệp: " Crown architecture and leaf habit are associated with intrinsically diﬀerent light-harvesting eﬃciencies in Quercus seedlings from contrasting environments" ppt

Ngày tải lên : 07/08/2014, 16:20

... node within the crown, the internode and petiole angles and azimuths, the angle and azimuth of the leaf surface normal, and the azimuth of the midrib were recorded with a compassprotractor Leaf, ... according to their functional and structural crown architectures, and this arrangement was consistent with their environmental conditions Similar ordinations have been found according to traits ... of full sunlight), leading to ca 25 mol photon m−2 day−1 of photosynthetically active radiation during clear spring days Seedlings were arranged randomly according to their species in the tunnel...

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Báo cáo khoa học: "Carbonic anhydrase XII expression is associated with histologic grade of cervical cancer and superior radiotherapy outcome" ppsx

Ngày tải lên : 09/08/2014, 09:20

... discovered that CA12 expression was strongly associated with histologic grades of the cervical cancer As CA12 and histologic grade were significantly associated with each other, we then examined whether ... structure and molecular functions which relate to CA12 in gene ontology analysis CA12, histological grade, and survival outcomes Positive CA12 expression was marginally associated with superior ... cervical cancer: correlation with clinicopathological characteristics The new combined category of CA12 expression and histological grade is significantly associated with survival outcomes Total...

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Báo cáo khoa học: "Combined low initial DNA damage and high radiation-induced apoptosis confers clinical resistance to long-term toxicity in breast cancer patients treated with high-dose radiotherapy" pdf

Ngày tải lên : 09/08/2014, 09:20

... into account the initial DNA damage and radiation-induced apoptosis levels, and introduces new data which may help to understand and define the complex mechanisms behind the normal tissue toxicity ... Almodovar JM: Early and late skin reactions to radiotherapy for breast cancer and their correlation with radiation-induced DNA damage in lymphocytes Breast Cancer Res 2005, 7:R690-698 Bourton EC, Plowman ... radiosensitivity of cancer patients and radiation-induced apoptosis in PBLs [41,42] The lack of uniformity in experimental design helps to understand these differences Thus, the cells used in the assay (total...

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Báo cáo y học: "Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level" doc

Ngày tải lên : 09/08/2014, 22:23

... diluted to 10 nM From one to seven indexed libraries were combined together into one pool, denatured with NaOH, and then 2.3 pM of each pool was loaded into one lane of an Ilumina GA flow cell and ... centrifuged to separate plasma from blood cells and plasma was withdrawn and stored in 1-ml aliquots at -80°C prior to plasma lipid extraction For each sample, 0.5 ml plasma was added to a glass ... deuterated standards for AEA and 2-AG together with calculation of the other EC metabolites was based on a ratio to the deuterated standards and was performed on an Agilent 6410 liquid chromatography...

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Caffeine and a selective adenosine A2A receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice pot

Ngày tải lên : 10/08/2014, 05:21

... England) The intensity of the band was quantified with a densitometric analysis (GS-800 Calibrated Densitometer, Bio-Rad), and calculated as the optical density × area of band Page of 10 on day and ... caffeine interacts with the nigrostriatal dopaminergic pathway to modulate its motor-stimulating effect The anatomical and functional interactions between the adenosine and dopamine receptors in the ... × 1.0 mm, I.D., Tokyo, Japan), a CMA-160 On-line injector (CMA/Microdialysis, Stockholm, Sweden), a microbore LC system with a dual potentiostat amperometric detector BAS-4C and the MF-1020 electrode...

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Báo cáo khoa hoc:" Functional polymorphisms in the promoter regions of MMP2 and MMP3 are not associated with melanoma progression" potx

Ngày tải lên : 11/08/2014, 08:21

... expressed in melanocytes and their overexpression has been linked to tumor development, progression and metastasis [2-5] Certain MMPs are associated with generalized growth and expansion of the cell ... history, moles and freckling pattern, nevus density, hair and eye color, propensity to sunburn and ability to tan after sun exposure The information on hair color, eye color and propensity to ... statistical analysis and contributed to the materials and methods section; DC, AH and AH contributed with subject accrual and discussions; KB contributed with pathology review; BR and CS participated...

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Báo cáo y học: "Rho iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation" ppt

Ngày tải lên : 11/08/2014, 08:22

... ERK1/2, p38 and JNK in RAW 264.7 cells (Fig 1B) Next, RAW cells were transfected with either NF-κB or CRE firefly luciferase construct, treated without or with RIAA (1, and 10 μg/ml), and followed ... inflammatory signaling pathways in RAW 264.7 cells Effect of1 Effect of RIAA on LPS-induced inflammatory signaling pathways in RAW 264.7 cells (A) Cells were incubated for h with RIAA (0, 10 and ... of soluble receptor activator of NF-κB-ligand (sRANKL) was added After days, medium and all reagents were replaced and incubation was continued for more days Cells were washed with ice cold PBS,...

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báo cáo khoa học: "A consensus linkage map for molecular markers and Quantitative Trait Loci associated with economically important traits in melon (Cucumis melo L.)" pptx

Ngày tải lên : 11/08/2014, 11:21

... carotenoid accumulation and flesh color co-localized with carotenoid-related genes: CMCRTR and BOH_1 in LG VI and CMBCYC and LYCB in LG VIII (Figures and 4), and as such become candidate genes for ... framework map and markers were located subsequently to their respective bins from the IRTA to the framework map Trait and QTL definition Traits and QTL were selected from 17 published works and unpublished ... markers to customize mapping and molecular breeding applications, such as fine mapping, the development of novel genetic stocks (e.g., nearly isogenic lines and inbred backcross lines), MAS, and...

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báo cáo khoa học: " ABO blood group and other genetic variants associated with pancreatic cancer" ppt

Ngày tải lên : 11/08/2014, 12:20

... GWAS to derive ABO genotypes (OO, AO, AA, AB, BO and BB) and ABO sero types (A, B, AB and O) and then examined the association of these two measures with pancreatic cancer risk [13] Patients with ... cancer were compared with controls without pancreatic cancer and matched for year of birth, gender, race/ethnicity and source of DNA, and four of the cohorts were matched for smoking status and ... 1q32.1 and 5p15.33 associated with an increased risk of pancreatic cancer The locus on 13q22.1 was associated with SNP rs9543325, in a non-genic region between the transcription factor genes KLF5 and...

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Báo cáo y học: " Sociodemographic and occupational risk factors associated with the development of different burnout types: the cross-sectional University of Zaragoza study" docx

Ngày tải lên : 11/08/2014, 15:22

... feel for their work and by their desire for change These people have lost their objectivity with respect to their natural right to experience needs for personal development and to try to pursue ... insufficient motivation and, given their talents and/ or skills, have to cope with monotonous and unstimulating conditions that fail to provide the necessary satisfaction Workers with “worn-out” burnout ... dimensions Subjects had to indicate the degree of agreement with each of the statements presented according to a Likert-type scale with response options, scored from (totally agree) to (totally disagree)...

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Báo cáo y học: "Seropositivity is associated with insulin resistance in patients with early inflammatory polyarthritis: results from the Norfolk" pot

Ngày tải lên : 12/08/2014, 18:20

... insulin resistance with other autoantibodies RA and its related conditions overlap with other autoimmune conditions and affects many organs It is possible that the same triggers to autoimmune RF and ... (IP) and is particularly associated with seropositive disease [1-4] Insulin resistance (IR) is known to be increased in patients with established RA [5,6] and has been shown to be a risk factor ... patients with inflammatory polyarthritis (IP) especially in seropositive disease In established RA, insulin resistance (IR) is increased and associated with CVD We investigated factors associated with...

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