analysis of exhaled breath condensate potential implications for diagnosis and therapy of lung diseases
Báo cáo y học: "κ The roles of the classical and alternative nuclear factor-κB pathways: potential implications for autoimmunity and rheumatoid arthritis" ppsx
... advantages and disadvantages of anti-inflammatory and anti-rheumatic NF-κB inhibitors, and the effects (in animal models of RA and other autoimmune diseases) of genetically inactivated NF-κB subunits and ... needed for B-cell maturation and for protection of otherwise negatively selected B cells It is also needed for plasma cell differentiation and survival, and it is these cells that are responsible for ... producers of IL-17 We then discuss the biologic effects of Th17 and IL-17 in the context of RA, and the direct Page of 14 (page number not for citation purposes) Arthritis Research & Therapy Vol...
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báo cáo hóa học: " Method optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography-electrospray ionization tandem mass spectrometry" doc
... Validation of leukotriene B4 measurements in exhaled breath condensate Inflamm Res 2003, 52:69-73 Mutlu GM, Garey KW, Robbins RA, Danziger LH, Rubinstein I: Collection and analysis of exhaled breath condensate ... for each compound are listed in Table and were performed with continuous flow injections of standard solutions of all analytes with a Page of (page number not for citation purposes) Journal of ... labelled standard [2H4] LTB4 was used for the correction of leucotriene response values, whereas [2H4] PGE2 was used for prostaglandins and 8-isoprostane For quantification, the peak area ratio of prostaglandins...
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Báo cáo y học: "Effects of salbutamol on exhaled breath condensate biomarkers in acute lung injury: prospective analysis" pps
... Measurement of exhaled breath condensate pH: implications for pathophysiology and monitoring of inflammatory airway diseases In New Perspectives in Monitoring Lung Inflammation Analysis of Exhaled Breath ... P, van Rensen EL, Rubinstein I, Silkoff P, ATS/ERS Task Force on Exhaled Breath Condensate, et al.: Exhaled breath condensate: methodological recommendations and unresolved questions Eur Respir ... Page of (page number not for citation purposes) Critical Care Vol 12 No Roca et al Table Exhaled breath condensate biomarkers before and after salbutamol administration Salbutamol P value Before...
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Báo cáo sinh học: "A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases" docx
... data analysis and drafted the results of the manuscript HK and GL participated in the design of the study and carried out the statistical analysis JH and AK participated in the identification of ... individual autoAb and total PSA separately while providing the simplicity and cost-effectiveness of a multiplex assay that requires less sample and handling time of quantifying or more autoAb and PSA simultaneously ... more and more studies have shown the significance of circulating autoAb in serving cancer detection, diagnosis, prognosis, and other areas [12-14], sensitive and cost-effective detection of autoAb...
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báo cáo hóa học:" A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases" ppt
... data analysis and drafted the results of the manuscript HK and GL participated in the design of the study and carried out the statistical analysis JH and AK participated in the identification of ... individual autoAb and total PSA separately while providing the simplicity and cost-effectiveness of a multiplex assay that requires less sample and handling time of quantifying or more autoAb and PSA simultaneously ... more and more studies have shown the significance of circulating autoAb in serving cancer detection, diagnosis, prognosis, and other areas [12-14], sensitive and cost-effective detection of autoAb...
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Báo cáo y học: "Effect of allergen-specific immunotherapy with purified Alt a1 on AMP responsiveness, exhaled nitric oxide and exhaled breath condensate pH: a randomized double blind study" ppsx
... responsiveness index; ENO = exhaled nitric oxide; FEV1= forced expiratory volume in second; FVC = forced vital capacity; EBC = exhaled breath condensate Lung function Exhaled breath condensate pH In both ... Respiratory Society: ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide Am J Respir Crit Care ... article as: Prieto et al.: Effect of allergen-specific immunotherapy with purified Alt a1 on AMP responsiveness, exhaled nitric oxide and exhaled breath condensate pH: a randomized double blind study...
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Báo cáo y học: "A quantitative evaluation of gross versus histologic neuroma formation in a rabbit forelimb amputation model: potential implications for the operative treatment and study of neuromas" ppt
... specific for the needs of this model; XD performed critical macroscopic and microscopic analysis of the histologic specimens; and TK and GD participated in the design and coordination of the model ... evaluation of gross versus histologic neuroma formation in a rabbit forelimb amputation model: potential implications for the operative treatment and study of neuromas Journal of Brachial Plexus and ... grouped according to nerve (median, radial, and ulnar nerves), and an analysis of variance (ANOVA) with Bonferroni post-test analysis was performed for each of the three following histomorphometric...
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Báo cáo y học: "Eotaxin-1 in exhaled breath condensate of stable and unstable asthma patients" pdf
... questions concerning the lack of standardization for both the collection and analysis of EBC, the repeatability of measurements, and the effect of many factors on concentrations of EBC markers, are still ... each stage of the life cycle of eosinophil, and therefore plays a very important role in the development of allergic reaction This chemokine is responsible for the release of progenitors of eosinophils ... pathophysiology and evaluation of new strategies for the treatment of asthma - especially for the assessment of inflammatory mediators related to the bronchial epithelium [7] However, the analysis of EBC...
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Báo cáo y học: " Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers" potx
... the EBC pH measurements, in order to ensure consistency of results Exhaled Breath condensate collection and pH measurement Exhaled breath condensate (EBC) was collected using a commercially available ... recruitment of patients and study measurements KK, AIP and MM performed the statistical analysis AIP and KK drafted the manuscript KIG, MA, SP and SL were involved in revising the manuscript for important ... Identification of acid reflux cough using serial assays of exhaled breath condensate pH Cough 2006, 2:3 doi:10.1186/1465-9921-12-67 Cite this article as: Papaioannou et al.: Exhaled breath condensate...
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Báo cáo y học: " Comparison of exhaled breath condensate pH using two commercially available devices in healthy controls, asthma and COPD patients" pptx
... Eighties [1,2] The use of EBC collection and analysis has several advantages: It is non-invasive, easy to use, allows repeated sampling, and is suitable for analysis of children and patients with ... any of the study groups, except for one mild form of hyperventilation on the ECoScreen in the HC group After collection, 200 μl of each sample was immediately removed for pH analysis Effect of ... obtain a wide range of pH values and to address methodological questions in relevant patient groups Our results on the performance of the RTube and ECoScreen for pH analysis of EBC in healthy controls...
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Báo cáo y học: " Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced " pps
... rate to 85% of the maximum predicted for the age of each patient [15] Basic spirometric parameters were recorded before, and immediately after, the exercise test, and 1, 5, 10, 15, 20, and 60 minutes ... temperature of collection was around 0°C [10,16] Exhaled breath collections were performed before, 10, 30, 60 minutes, and 24 hours after the exercise challenge test Patients were instructed to breathe ... performed to clarify the possible role of ET1 in the pathogenesis of EIB, particular in the inflammatory basis of this condition and the remodeling of the airways We show that, as a result of...
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Báo cáo y học: "No effect of omeprazole on pH of exhaled breath condensate in cough associated with gastro-oesophageal reflux" pdf
... (40 mg/day x 14d) Figure and after in exhaled treatment pH valuesomeprazolebreath condensate in patients before pH values in exhaled breath condensate in patients before and after omeprazole treatment ... changes in pH of the exhaled breath condensate We conclude that these measurements not reflect the clinical response Additionally, omeprazole does not change the pH of exhaled breath condensate, ... subject coughed times or more The concentration of capsaicin causing coughs or more (C5) was recorded Exhaled breath condensate collection Exhaled breath condensate (EBC) was obtained non-invasively...
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Báo cáo y học: " Identification of acid reflux cough using serial assays of exhaled breath condensate pH" pot
... by means of an zation) before and after and after a water control standardiRepeated exhaled breath condensate pH (after gas(Figure 1B) Repeated exhaled breath condensate pH (after gas standardization) ... University of Virginia and all subjects provided informed consent Collection of exhaled breath condensate Individual EBC samples were collected without nose clips during minutes of relaxed breathing ... Resolver Percentage of subjects 100% Positive EBC pH Profile Negative EBC pH Profile Figure Multi-sample EBC pH profiles of controls and patients Multi-sample EBC pH profiles of controls and patients...
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Báo cáo y học: "Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages" pot
... Figure conformers Modular3flexibility for each protein of the dataset of proteins with Modular flexibility for each protein of the dataset of proteins with conformers (a) Averages of normalized ... each other, and, therefore, exhibiting a certain degree of homotropic cooperativity [32] Binding of one androstenedion (Andro2) induces conformational changes in the active site and increases ... intervals of modularity The bars represent the percentage of functional modules for each interval of modularity The number of functional modules for each range of modularity is indicated at the top of...
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Rural and Micro Finance Regulation in Ghana: Implications for Development and Performance of the Industry ppt
... Rural and Micro Finance Regulation in Ghana: Implications for Development and Performance of the Industry By William F Steel & David O Andah June 2003 Foreword his country study is one of three ... Annex 1: Microfinance Legislation in Uganda and Ethiopia 40 Annex 2: Evolution of Legal Framework for RMFIs 43 Annex 3: Summary of Laws and Regulations for RMFIs and Businesses ... Ghana: Implications for Development and Performance of the Industry William F Steel and David O Andah I Background A Introduction The purpose of this paper is to assess how the policy, le gal and...
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Báo cáo hóa học: "Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy" pdf
... pfu/cell of Ad5-CMV-GFP vector D) FACS analysis profile of different PDAC cell lines after days of Adeno5-CMV-GFP infection (13.6 pfu/cell) E) Luminescence analysis for the permissivity of MxA+ and ... 2,5% FBS), at 1,200 rpm for minutes at +4° C and fixed with 4% paraformaldehyde Cyto-fluorimetric analysis was performed using FACS Canto cytofluorimeter and the FACS Diva software (Becton Dickinson, ... Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA 5Department of Surgery, University of Verona Medical School, Verona, Italy Page 10 of 11 Authors’...
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Báo cáo y học: " Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during different phases of T cell responses: implications for arthritis and autoimmune disease" pot
... regulator of CTLA-4 function and dissociates from CTLA-4 upon ligand binding The ligands are the dimeric CD80 and the monomeric CD86 Binding of CD80 to the divalent CTLA-4 leads to the formation of ... due to different kinetics of expression on different cell types The crystal structures and an analysis of the binding affinities and kinetics of CTLA-4 with its ligands suggest that CD86 monomers ... a good marker for identifying Treg cells viable for the autologous cell therapy of chronic inflammations Polymorphisms of CTLA-4 in rheumatoid arthritis (RA) and other autoimmune diseases 50 The...
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Báo cáo y học: "The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases" pot
... CS: Differential expression of Fas and Fas ligand in acute and chronic graftversus-host disease: up-regulation of Fas and Fas ligand requires CD8+ T cell activation and IFN-gamma production J ... with SLE since production of IL-2 and the active form of TGF-β is decreased [53] Figure The role of transforming growth factor-β (TGF-β) in the differentiation pathway of CD4+ regulatory T cells ... appear to be crucial for the prevention of spontaneous autoimmune diseases, they have been called ‘professional’ suppressor cells [5,8] In general, the properties of rodent and human CD4+ CD25+...
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Báo cáo y học: "Uses, traditional management, perception of variation and preferences in ackee (Blighia sapida K.D. Koenig) fruit traits in Benin: implications for domestication and conservatio" pptx
... to the Guinean forests of West Africa The fleshy arils of the ripened fruits are edible Seeds and capsules of the fruits are used for soap-making and for fishing, and all parts of the tree have ... and mulching were very important for the Batombu, Otamari and Natemba The result of the principal component analysis (PCA) performed on the indigenous knowledge, the perception of variation and ... their land for its utility as medicine and myth; use of the dried, boiled or fried aril; favour the use of the soap and as repellent; they perceived variation in fruit size and shape, seed size and...
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Báo cáo y học: "Folklore and traditional ecological knowledge of geckos in Southern Portugal: implications for conservation and scienc" doc
... consists of 28 species of reptiles and 17 species of amphibians [42] that exhibit a wide variety of shapes, colors, behaviors and lifestyles, The distribution of Iberian herpetofauna is profoundly ... TEK and folklore play a beneficial role in nature conservation, such as the importance of taboos and social norms for the conservation of species and habitats [5-9], the importance of folklore and ... source of southern Portuguese gecko folklore and TEK, as well as their possible impact on future scientific studies of geckos and their conservation Page of Natural and Cultural History of Geckos and...
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