adipokine production by adipose tissue a novel target for treating metabolic syndrome and its sequelae
báo cáo khoa học: "Gene-expression and network-based analysis reveals a novel role for hsa-mir-9 and drug control over the p38 network in Glioblastoma Multiforme progression" ppsx
... tumor and its matched normal sample across all patients Table 2: Glioblastoma drug targets Drug name Target Pathway Accutane RARA Map kinase inactivation of smrt co-repressor CCNU STMN4 Signaling ... mediated by p38-gamma and p38-delta pathway Celebrex COX2 Signaling mediated by p38-alpha and p38-beta pathway Cis Retinoic Acid RARA Map kinase inactivation of smrt co-repressor Sorafenib RAF1 ... signaling mediated by MAPKAP kinases Tamoxifen ESR1 Signaling mediated by p38-alpha and p38-beta pathway Six out of the 69 drugs in The Cancer Genome Atlas (TCGA) clinical dataset that targets...
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A novel sec7 domain containing protein BIG3 and its role in regulated secretory pathway
... CCC AGC CGG AAG AAG-3’ and 5’-CGC GTC GAC CAC AAT GAT GTC ATA GAC-3’ and digested with BamHI-SalI and ligated to C-terminal of EcoRI-BamHI fragment in pUC19 The full length of BIG3 at EcoRI-SalI ... pair: 5’-GCC GAA TTC CCA GAT GCT AAA GAA G-3’ and 5’-TAT GTC GAC AGG CCT GAG AGA TCC A- 3’ The PCR product was digested by EcoRI-SalI and ligated into pET-41b(+) vector His-BIG1Sec7 was generated ... sorting machinery Two major sorting machineries, ‘Sorting by entry’ and ‘Sorting by retention’, have been suggested (Arvan and Castle, 1998; Arvan and Halban, 2004; Kuliawat and Arvan, 1994) Each...
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Development of a novel immersed boundary lattice boltzmann method and its applications
... extended to simulate the 2D and 3D moving boundary flow problems (Udaykumar et al 2001; Marella et al 2005) and solidification problems (Udaykumar and Mao, 2002; Yang and Udaykumar, 2005) 1.2.2 ... most popular boundary conforming method is perhaps the arbitrary Lagrangian-Eulerian (ALE) approach (Hirt et al 1974; Hu et al 2001; Anderson et al 2004; Chew et al 2006) In many applications, ... restoring force at the boundary Chapter Introduction point 1.2.2.3 Advantages and disadvantages of IBM The major advantage of IBM is its simplicity and easy implementation This is attributed...
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THE STUDY OF a NOVEL MIXED LINEAGE LEUKEMIA 5 ISOFORM AND ITS ASSOCIATION WITH HUMAN PAPILLOMAVIRUS 16 18 RELATED HUMAN CERVICAL CANCERS
... GTGTTGGTAAAGGTAGGCTAGC MLL5β Forward GAAAACCCAGAGTGCCCTGTTCTA Reverse CAATATACGCGAGACTAGTCTT GAPDH Forward GTGAAGGTCGGAGTCAACG Reverse TGAGGTCAATGAAGGGGTC HPV16E6 Forward CTGCAATGTTTCAGGACCCA Reverse ... GACAAGAGCATAGTGATCCCA MLL5β M5b_NotI.rev AAGGAAAAAAGCGGCCGCCAATATACGCGA GACTAGTCTT GFPMLL5β M5b_SalI .for ACGCGTCGACATGAGCATAGTGATCCCATTG M5b_BamHI.rev CGCGGATCCCAATATACGCGAGACTAGTCTT Primers used for ... CATCTGACATATTTTCCCGCTTCCGGCGTTGT AGTAGCAC 36 GFP- M5_Y35 8A. for AGAGGGAAGTTTATG MLL5β‐ SET mut ATTTGCCTCCTGATGCACTTATCATTGAAGCC M5_Y35 8A. rev CATAAACTTCCCTCTGGCTTCAATGATAAGTG CATCAGGAGGCAAAT...
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Báo cáo y học: "Asthma is a risk factor for acute chest syndrome and cerebral vascular accidents in children with sickle cell disease" ppt
... hypoxemia, and a new infiltrate on chest x-ray that required hospitalization and a transfusion of packed red blood cells A cerebral vascular accident diagnosis was based on the new onset of an acute ... intermittent asthma, each with mild persistent and moderate persistent asthma, and with severe persistent asthma No patient had Page of (page number not for citation purposes) Clinical and Molecular Allergy ... supported an asthma diagnosis Most patients with asthma are not cared for by asthma specialists and frequently the diagnosis is made on clinical grounds without formal pulmonary function testing Additionally,...
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Development of bordetella pertussis as a live vehicles for heterologous antigens delivery, and its application as a universal influenza a vaccine
... of mucosal routes have been considered for vaccination purposes, including the oral, nasal, rectal and vaginal routes By far oral and intranasal vaccinations have been the most commonly and extensively ... hemagglutinin (HA) and neuraminidase (NA) However, HA and NA can undergo mutations through antigenic drift and shift, the vaccine formulations need to be changed on a yearly basis in order to match ... ADP Adenosine diphosphate AMs Alveolar macrophages Amp Ampicillin APS Ammonium persulphate APC Antigen-presenting cell BALFs Broncho-alveolar lavages fluids BALT Bronchial-associated lymphoid tissue...
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Domestic Wastewater Reclamation Coupled with Biofuel/Biomass Production Based on Microalgae: A Novel Wastewater Treatment Process in the Future
... Carbon Capture and Storage (CCS) Organic flocculants Primary Flocculation settlement tank and filtration CO2 Wetland plants Microalgae cultivation and reclamation Wastewater Artificial wetland ... the wastewater treatment and biofuel/biomass production In the novel process, the primary settlement tank units, anaerobic fermentation, artificial wetland and disinfection all have relatively ... be applied By separating microalgal cells from the wastewater, clean water with low content of organics and inorganic nutrients could be obtained, and also the microalgal biomass could be harvested...
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Báo cáo khoa học: Alpha 1-antichymotrypsin/SerpinA3 is a novel target of orphan nuclear receptor Nur77 potx
... CCTCCAAAAAGCACACAGA-3¢ for St-182 and St-93/ -182, 5¢-AGAAATTATCATCTTTTCCAGTCCGAGA-3¢ for St-93 and St-93/-182, and 5¢-TGGTCTTGAACTCCT CGTGATCTGCCCA-3¢ for Lst-595 pcDNA3.1-Nur77 expression plasmid ... 5¢-GACTCGCAGACAATGATGG TC-3¢ and 5¢-GCAAACTCATCATGGGCACC-3¢ The results were normalized with b-actin, for which the primers were 5¢-ATGGTGGGAATGGGTCAGAAG-3¢ and 5¢-CA CGCAGCTCATTGTAGAAGG-3¢ Another ... pcDNA3.1-GST-Nur77 plasmid pSilencer-shNur77 was prepared by overlapping strategy with primers 5¢-gacGGATCCgcagtccagccatgctccttt caagagaaggagcatg-3¢ (with BamHI), 5¢-cggAAGCTTtATC GATccaaaaaacagtccagccatgctccttctcttg-3¢...
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Báo cáo hóa học: "Exhaustive expansion: A novel technique for analyzing complex data generated by higherorder polychromatic flow cytometry experiments" pot
... 18 Tateishi-Yuyama E, Matsubara H, Murohara T, Ikeda U, Shintani S, Masaki H, Amano K, Kishimoto Y, Yoshimoto K, Akashi H, Shimada K, Iwasaka T, Imaizumi T: Therapeutic angiogenesis for patients ... JCS, LW, AR, BZ, and EBW analyzed and interpreted the data JCS and EBW wrote the manuscript All authors have read and approved the final manuscript Competing interests JCS is Founder and President ... data analysis as suggested by the data itself and the underlying science For example, while we used a statistical test to quantify peaks in the melanoma study, we could have defined peaks based...
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Báo cáo toán học: " A novel method for crystalline silicon solar cells with low contact resistance and antireflection coating by an oxidized Mg layer" ppt
... resistance To calculate the contact resistance, Mg was evaporated on the n-Si wafer, and the Ag paste was printed on the Si wafer for reference The contact resistances of Mg/Si and Ag/Si were measured ... followed by an n+ layer formed by POCl3 doping Doping was carried out at 810°C for min, and the resulting sheet resistance was 100 /sq A phosphorous silicate glass layer was removed and rinsed with a ... ohmic contact with an n+ region, a new material can be inserted between Ag and Si to form low barrier height (ΦB) and thus to reduce the contact resistance Among various materials, Mg metal is selected...
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Báo cáo y học: "SHROOM3 is a novel candidate for heterotaxy identified by whole exome sequencing" pptx
... TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCAAGCAGGTTGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCGAGCAGGTTGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC t p.G60V ... Gorilla gorilla Pongo pygmaeus Macaca mulatta Callithrix jacchus TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC ... manuscript SL and TS evaluated and interpreted SNP microarray and aCGH data All authors read and approved the final manuscript for publication Acknowledgments We thank the heterotaxy patients and families...
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báo cáo khoa học: " A novel method for efficient and abundant production of Phytophthora brassicae zoospores on Brussels sprout leaf discs" pot
... oleracea var gemmifera) and rutabaga (swedes) (Brassica napus var napobrassica) [6,7] P brassicae is mostly associated with post-harvest damage that limits the marketability of cabbage heads and can ... Netherlands The Netherlands Brassica rapa subsp.pekinensis Brassica oleracea var alba Brassica oleracea var.gemmifera Brassica rapa subsp.pekinensis Brassica oleracea var.gemmifera 2.9 0.1 4.9 0.4 ... Hyaloperonospora arabidopsidis, Albugo candida and two Phytophthora species, P cinnamoni and P brassicae [1,11-13] The best studied Phytophthora species, i.e P infestans and P sojae, are incapable...
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Báo cáo y học: "A novel method for purifying bluetongue virus with high purity by co-immunoprecipitation with agarose protein A" ppsx
... of each plate were cultured as the control group The two plates were placed at 37°C with 5% CO2 and CPE was observed everyday for days And TCID50 was calculated using Karber formula Purification ... first purification of the antibodies was precipitation by saturated (NH4)2SO4 The sediment was resolved in 0.9% NaCl solution and was dialyzed by PBS at 4°C and the dialysis buffer was changed every ... was perfectly shown in picture A Picture B was photographed by film and the virions were marketed by arrows In picture B, an uncoated BTV virion was observed and was marked by arrow Biological...
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Báo cáo sinh học: " Genetic and metabolic aspects of androstenone and skatole deposition in pig adipose tissue: A review" ppt
... androstadienol sulfate hydroxysteroid sulfotransferase HO 5,16-androstadien-3β-ol O 4,16-androstadien-3-one Final products of androstenone sulfonation 5α-androsten-3β-ol (β-androstenol) SRD 5A 3βHSD ... SRD 5A 3βHSD 3α-androstenol sulfate hydroxysteroid sulfotransferase 3β-androstenol sulfate HO 5α-androsten-3α-ol (α-androstenol) hydroxy-androstenone sulfate 3αHSD O androstenone hydroxy-androstenone ... Erratum O O CYP1 1A HO 3βHSD HO O progesterone pregnenolone cholesterol CYP21 andien-β synthetase (CYB5, CYP17…) 11-deoxycorticosterone 11- 4,16-androstadien-3-ene 4,16-androstadien- 3βHSD androstadienol...
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Báo cáo sinh học: "Genetic and metabolic aspects of androstenone and skatole deposition in pig adipose tissue: A review (Open Access publication)" potx
... for boar taint: skatole and androstenone and their correlations with sexual maturation., Acta Vet Scand 48 (Suppl 1) S9 (2006) 22–23 [46] Tambyrajah W.S., Doran E., Wood J.D., McGivan J.D., The ... role in catalysing the first step of skatole degradation and a defective hepatic skatole metabolism will lead to skatole accumulation in fat Low skatole levels in fat have been associated with ... discussed androstenone and skatole metabolisms as equivalent processes It is important to recall that metabolization of skatole is necessary to eliminate xenobiotic substrates whereas storage of androstenone...
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Báo cáo y học: "Creation and disruption of protein features by alternative splicing a novel mechanism to modulate function" docx
... tract binding protein by alternative splicing leading to nonsense-mediated decay Mol Cell 2004, 13:91-100 Garcia-Blanco MA, Baraniak AP, Lasda EL: Alternative splicing in disease and therapy Nat ... paper Additional data file is a table listing the TM domains that are encoded by two exons Additional data file contains the number of ESTs/RefSeqs and information about the tissues or libraries ... second TM domain In general, any EST-based approach is hampered by the bias of publicly available EST databases towards cancer-related tissues or cell lines that may exhibit aberrant splicing...
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Tài liệu BÁO CÁO " LIPID PRODUCTION FROM MICROALGAE AS A PROMISING CANDIDATE FOR BIODIESEL PRODUCTION " ppt
... per unit area of land, compared to terrestrial oilseed crops Microalgae are very efficient biomass capable of taking a waste (zero energy) form of carbon (CO2) and converting it into a high density ... Materials and Methods Materials A microalgal strain of C vulgaris was kindly provided by Prof Hong-Nong Chou of The Institute of Fisheries Science, National Taiwan University, Taiwan All solvents and ... 48 MAKARA, TEKNOLOGI, VOL 13, NO 1, APRIL 2009: 47-51 energy crops [6-7] Microalgae systems also use far less water than traditional oilseed crops For these reasons, microalgae are capable of...
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Tài liệu BÁO CÁO " LIPID PRODUCTION FROM MICROALGAE AS A PROMISING CANDIDATE FOR BIODIESEL PRODUCTION " docx
... per unit area of land, compared to terrestrial oilseed crops Microalgae are very efficient biomass capable of taking a waste (zero energy) form of carbon (CO2) and converting it into a high density ... Materials and Methods Materials A microalgal strain of C vulgaris was kindly provided by Prof Hong-Nong Chou of The Institute of Fisheries Science, National Taiwan University, Taiwan All solvents and ... 48 MAKARA, TEKNOLOGI, VOL 13, NO 1, APRIL 2009: 47-51 energy crops [6-7] Microalgae systems also use far less water than traditional oilseed crops For these reasons, microalgae are capable of...
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Báo cáo khoa học: Characterization of the rice carotenoid cleavage dioxygenase 1 reveals a novel route for geranial biosynthesis ppt
... Journal compilation ª 2008 FEBS No claim to original German government works 743 A novel route for geranial formation A Ilg et al to the peak area of the internal standard, which was quantified at ... localization and induction by highlight Mol Microbiol 69, 231–244 Prado-Cabrero A, Estrada AF, Al-Babili S & Avalos J (2007) Identification and biochemical characterization of a novel carotenoid oxygenase: ... medium for 30 For HPLC analyses, cells were harvested after h, and carotenoids were extracted and processed as described above Analytical methods For HPLC analyses, a Waters system equipped with a...
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Báo cáo khoa học: The human pyridoxal kinase, a plausible target for ginkgotoxin from Ginkgo biloba docx
... treatment for (a) and 60 (b) with alkaline phosphase (Merck, Darmstadt, Germany; 100 U) at 37°C, as analyzed by HPLC Influence of ginkgotoxin on human pyridoxal kinase This material is available as part ... DL, WagnerMcPherson CB, Evans GA & Tobin AJ (1992) Two human glutamate decarboxylases, 65- kDa and 67- kDa GAD, are each encoded by a single gene Proc Natl Acad Sci USA 89, 2115–2119 10 Nitsch ... PKH leads inter alia to a decreased availability of PLP for GAD, which catalyses the formation of c-aminobutyric acid, the most potent inhibitory neurotransmitter in the mammalian brain Decreased...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25